Title: Hotels in Santa María Centro - Best Santa María Centro Hotels from £49 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa María Centro](https://expedia.co.uk/Santa-Maria-Centro-Holiday-Rentals.d553248635923647958.Travel-Guide-HolidayRentals)[Santa María Centro Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Centro.d553248635923647958.Car-Hire-Guide)[Santa María Centro Holidays](https://expedia.co.uk/Santa-Maria-Centro.d553248635923647958.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa María Centro from £49 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [21 Nov - 22 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-11-22&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santa María Centro hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/5de82f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/a4b200bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/eae29abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/e3286d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amerian Rafaela Hotel Rafaela 8.8/10 Excellent (43) "Nice hotel and staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix £49 21 Dec - 22 Dec [](https://www.expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-05&endDate=2025-12-06®ionId=553248635923647958&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248635923647958) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels) ## Top Santa María Centro Hotel Reviews ![Amerian Rafaela Hotel](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/5de82f5d_y.jpg) ### Amerian Rafaela Hotel 8/10 Good "La habitación impecable, limpia, cama cómoda. Pero la pileta estaba sucia, al ser una piscina pequeña no les llevaría más de 10 minutos tenerla en condiciones. En su reemplazo use el jacuzzi exterior pero no funcionaban los jets. El Gym muy pobre también. Por el resto todo Ok." [](https://expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) ## More cheap stays in Santa María Centro ![Parra Hotel& Suites](https://images.trvl-media.com/lodging/16000000/15470000/15462700/15462633/460a619a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Parra Hotel& Suites BV. SANTA FE 554,Rafaela, Santa Fe, Argentina Rafaela Santa Fe Province [Get rates](https://expedia.co.uk/Hotel-Search?startDate=05%2F12%2F2025&endDate=06%2F12%2F2025&selected=15462633&PinnedHotelID=15462633&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.co.uk/Rafaela-Hotels-Parra-Hotel-Suites.h15462633.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in Santa María Centro? > Located 21.4 mi (34.4 km) from the heart of Santa María Centro, [Amerian Rafaela Hotel](https://www.expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are [Parra Hotel& Suites](https://www.expedia.co.uk/Rafaela-Hotels-Parra-Hotel-Suites.h15462633.Hotel-Information) and [Hotel Toscano](https://www.expedia.co.uk/Rafaela-Hotels-Hotel-Toscano.h118000033.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958), or [vacation rentals in Santa María Centro](https://www.expedia.co.uk/Santa-Maria-Centro-Holiday-Rentals.d553248635923647958.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Santa María Centro, will I receive a refund? > Yes! The majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santa María Centro. ### What is staying in Santa María Centro like? > Visitors will definitely enjoy all that Santa María Centro has to offer. There are 4 hotels and other accommodation options in the surrounding area. Find out more about [Santa María Centro](https://www.expedia.co.uk/Santa-Maria-Centro.dx553248635923647958). ### What's the seasonal weather in Santa María Centro? > The hottest months are usually January and December, with an average temperature of 25°C, while the coldest months are July and June, with an average of 14°C. Average annual precipitation for Santa María Centro is 1161 mm. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Angélica Hotels](https://www.expedia.co.uk/Angelica-Hotels.d553248635924012085.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Barrio Fisherton](https://www.expedia.co.uk/Barrio-Fisherton-Rosario-Hotels-Gay-Friendly-Hotel.0-n553248635964996940-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bauer y Sigel Hotels](https://www.expedia.co.uk/Bauer-Y-Sigel-Hotels.d553248635924011523.Travel-Guide-Hotels) - [Cabal Hotels](https://www.expedia.co.uk/Cabal-Hotels.d553248635924011938.Travel-Guide-Hotels) - [Campo Piaggio Hotels](https://www.expedia.co.uk/Campo-Piaggio-Hotels.d553248635923281277.Travel-Guide-Hotels) - [Carlos Pellegrini Hotels](https://www.expedia.co.uk/Carlos-Pellegrini-Hotels.d553248635924012162.Travel-Guide-Hotels) - [Colonia Aldao Hotels](https://www.expedia.co.uk/Colonia-Aldao-Hotels.d553248635924011620.Travel-Guide-Hotels) - 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[Rosario Central Stadium](https://www.expedia.co.uk/Rosario-Central-Stadium-Rosario.d553248621563217270.Attraction) - [Rosario-Victoria Bridge](https://www.expedia.co.uk/Rosario-Victoria-Bridge-Granadero-Baigorria.d553248621532463752.Attraction) - [Visit San Lorenzo](https://www.expedia.co.uk/San-Lorenzo.dx6358759) - [Visit Santa Fe Province](https://www.expedia.co.uk/Santa-Fe-Province.dx6232320) - [Santa Fe Holidays](https://www.expedia.co.uk/Santa-Fe.d3131.Holidays-City-Breaks) - [Sunchales Holidays](https://www.expedia.co.uk/Sunchales.d3000378958.Holidays-City-Breaks) - [Car hire Las Palmeras](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Las-Palmeras.d3000425968.Car-Hire-Guide) - [Car hire Portugalete](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Portugalete.d553248635924012434.Car-Hire-Guide) - [Car hire San José](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Jose.d553248635924011913.Car-Hire-Guide) - [Car hire near Santa Fe Province](https://www.expedia.co.uk/Destinations-In-Santa-Fe-Province.d6232320.Car-Hire-Destinations) - [El Trébol Holiday Rentals](https://www.expedia.co.uk/El-Trebol-Holiday-Rentals.d553248635924011658.Travel-Guide-HolidayRentals) - [Santa Fe Holiday Rentals](https://www.expedia.co.uk/Santa-Fe-Holiday-Rentals.d3131.Travel-Guide-HolidayRentals) - [Book Hotels in Santa María Centro on Expedia.com.ar](https://www.expedia.com.ar/Santa-Maria-Centro-Hoteles.d553248635923647958.Guia-de-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)