Title: Hotels in Santa María Centro - Best Santa María Centro Hotels from £47 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa María Centro](https://expedia.co.uk/Santa-Maria-Centro-Holiday-Rentals.d553248635923647958.Travel-Guide-HolidayRentals)[Santa María Centro Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Centro.d553248635923647958.Car-Hire-Guide)[Santa María Centro Holidays](https://expedia.co.uk/Santa-Maria-Centro.d553248635923647958.Holidays-City-Breaks) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa María Centro from £47 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [5 Oct - 6 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Oct - 7 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santa María Centro hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/5de82f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/eae29abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/a4b200bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/e3286d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amerian Rafaela Hotel Rafaela 9.0/10 Wonderful (42) "Nice hotel and staff." £47 19 Oct - 20 Oct [](https://www.expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=553248635923647958&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels) ## Top Santa María Centro Hotel Reviews ![Amerian Rafaela Hotel](//images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/5de82f5d_y.jpg) ### Amerian Rafaela Hotel 8/10 Good "La habitación impecable, limpia, cama cómoda. Pero la pileta estaba sucia, al ser una piscina pequeña no les llevaría más de 10 minutos tenerla en condiciones. En su reemplazo use el jacuzzi exterior pero no funcionaban los jets. El Gym muy pobre también. Por el resto todo Ok." [](https://expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) ## More cheap stays in Santa María Centro ![Parra Hotel& Suites](https://images.trvl-media.com/lodging/16000000/15470000/15462700/15462633/460a619a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Parra Hotel& Suites BV. SANTA FE 554,Rafaela, Santa Fe, Argentina, Rafaela, Santa Fe Province [Get rates](https://expedia.co.uk/Hotel-Search?startDate=19%2F10%2F2025&endDate=20%2F10%2F2025&selected=15462633&PinnedHotelID=15462633&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.co.uk/Rafaela-Hotels-Parra-Hotel-Suites.h15462633.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Hotels Near Santa María Centro, Santa Fe Province - [Rafaela Hotels](https://expedia.co.uk/Rafaela-Hotels.d3000007210.Travel-Guide-Hotels) - [San Carlos Centro Hotels](https://expedia.co.uk/San-Carlos-Centro-Hotels.d553248635924012076.Travel-Guide-Hotels) - [Esperanza Hotels](https://expedia.co.uk/Esperanza-Hotels.d553248635923647959.Travel-Guide-Hotels) - [San Martín de las Escobas Hotels](https://expedia.co.uk/San-Martin-De-Las-Escobas-Hotels.d553248635924012097.Travel-Guide-Hotels) - [Humboldt Hotels](https://expedia.co.uk/Humboldt-Hotels.d553248635924011618.Travel-Guide-Hotels) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)