Title: Hotels in Santa María Centro - Best Santa María Centro Hotels from £69 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa María Centro](https://expedia.co.uk/Santa-Maria-Centro-Holiday-Rentals.d553248635923647958.Travel-Guide-HolidayRentals)[Santa María Centro Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Centro.d553248635923647958.Car-Hire-Guide)[Santa María Centro Holidays](https://expedia.co.uk/Santa-Maria-Centro.d553248635923647958.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [21 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2026-02-21&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Feb - 23 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635923647958&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa María Centro hotels ![Exterior detail](https://images.trvl-media.com/lodging/127000000/126530000/126529800/126529772/813bf13a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi](https://images.trvl-media.com/lodging/127000000/126530000/126529800/126529772/w837h581x0y0-1c486fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom](https://images.trvl-media.com/lodging/127000000/126530000/126529800/126529772/bb49c35c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Triple Room | Spa](https://images.trvl-media.com/lodging/127000000/126530000/126529800/126529772/fbd8c644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### PARRA HOTEL AND SUITES [](https://www.expedia.co.uk/Rafaela-Hotels-PARRA-HOTEL-AND-SUITES.h126529772.Hotel-Information) Rafaela £94 22 Feb - 23 Feb [](https://www.expedia.co.uk/Rafaela-Hotels-PARRA-HOTEL-AND-SUITES.h126529772.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/eae29abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/w3248h3120x0y0-30cfe3d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/25391e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/7c52245d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amerian Rafaela Hotel [](https://www.expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) Rafaela 9.0/10 Wonderful (47 reviews) "Nice hotel and staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix £69 16 Mar - 17 Mar [](https://www.expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-07&endDate=2026-03-08®ionId=553248635923647958&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_553248635923647958) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels) ## Top Santa María Centro Hotel Reviews ![Amerian Rafaela Hotel](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/5de82f5d_y.jpg) ### Amerian Rafaela Hotel 6/10 Okay "The shower box is leaking water to outside. The vent installed in the toilette is very noisy. The outlet frame located on the wall at the desk area is lose and was falling when used. Cleaning was good. " [](https://expedia.co.uk/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) ## More cheap stays in Santa María Centro ![Parra Hotel& Suites](https://images.trvl-media.com/lodging/16000000/15470000/15462700/15462633/460a619a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Parra Hotel& Suites BV. SANTA FE 554,Rafaela, Santa Fe, Argentina Rafaela Santa Fe Province [Get rates](https://expedia.co.uk/Hotel-Search?startDate=07%2F03%2F2026&endDate=08%2F03%2F2026&selected=15462633&PinnedHotelID=15462633&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.co.uk/Rafaela-Hotels-Parra-Hotel-Suites.h15462633.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa María Centro? > This central area is the heart of Santa María Centro and is very convenient for visitors. It's characterised by its tree-lined streets, historic buildings, and a good selection of shops, eateries, and services. Plaza San Martín is a key landmark, a large, well-maintained park that often hosts local events and provides a pleasant green space in the city centre. Avenida General San Martín, a main thoroughfare, runs through this district and is where you'll find many of the city's businesses and hotels. > > > Couples will find this central location ideal for a relaxing and enjoyable stay. You'll be within easy walking distance of quality restaurants, local cafes, and boutique shops, superb for an evening stroll. The proximity to Plaza San Martín also offers a pleasant spot for a quiet afternoon. > > > For solo travellers, staying in the centre offers convenience and ease of access to the city's amenities. You can easily navigate on foot to explore local attractions, and there are public transport options available if you wish to venture further afield. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa María Centro hotel booking with Expedia? ### How much is the nightly rate at a Santa María Centro hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Angélica Hotels ](https://www.expedia.co.uk/Angelica-Hotels.d553248635924012085.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Barrio Fisherton ](https://www.expedia.co.uk/Barrio-Fisherton-Rosario-Hotels-Gay-Friendly-Hotel.0-n553248635964996940-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bauer y Sigel Hotels ](https://www.expedia.co.uk/Bauer-Y-Sigel-Hotels.d553248635924011523.Travel-Guide-Hotels) - [Cabal Hotels ](https://www.expedia.co.uk/Cabal-Hotels.d553248635924011938.Travel-Guide-Hotels) - [Campo Piaggio Hotels ](https://www.expedia.co.uk/Campo-Piaggio-Hotels.d553248635923281277.Travel-Guide-Hotels) - 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