Title: Guadalupe District Travel Guide: Best of Guadalupe District, Santa Fe Travel 2026 | Expedia.co.uk [Hotels in Guadalupe District](https://expedia.co.uk/Guadalupe-District-Hotels.d553248635976481064.Travel-Guide-Hotels)[Flights to Santa Fe](https://expedia.co.uk/Cheap-Flights-To-Santa-Fe.d180028.Travel-Guide-Flights)[Things to do in Santa Fe](https://expedia.co.uk/Things-To-Do-In-Santa-Fe.d180028.Travel-Guide-Activities)[Guadalupe District Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Guadalupe-District.d553248635976481064.Car-Hire-Guide)[Guadalupe District Holidays](https://expedia.co.uk/Guadalupe-District.d553248635976481064.Holidays-City-Breaks) # Guadalupe District Travel Guide ## Santa Fe ![A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.](https://images.trvl-media.com/place/180028/cb561ed4-94b9-475c-a214-9227252293c1.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.](https://images.trvl-media.com/place/180028/cb561ed4-94b9-475c-a214-9227252293c1.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The church with a moonlit backdrop. #GoldenHour](https://images.trvl-media.com/place/180028/98adf7eb-b4ae-4580-89d7-f4be938f6dcf.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The Santa Fe Railyard is social place in the center of town where you can grab a bite to eat, access bike and walking trails, and on the weekends explore a great farmer's market. #newmexico #santafe](https://images.trvl-media.com/place/180028/6272b939-8c52-4e2a-8d2c-5af7c3cc8e86.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![This is a purely residential area with nothing to offer but great people and amazing Old Santa Fe architecture. It's one of those "only locals know" streets. #CeliaLuzPhotography #BW #architecture #SantaFe #NewMexico #statue #streetart #local #travel #angel ](https://images.trvl-media.com/place/180028/b922d07a-d348-4dfb-9018-d2b8b4f6a7e0.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Guadalupe District Things to do Hotels Where to stay [Santa Fe travel guide](https://expedia.co.uk/Santa-Fe.dx180028) --- ### Popular places to visit ![The Santa Fe Railyard is social place in the center of town where you can grab a bite to eat, access bike and walking trails, and on the weekends explore a great farmer's market. #newmexico #santafe](https://images.trvl-media.com/place/180028/6272b939-8c52-4e2a-8d2c-5af7c3cc8e86.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Railyard During your visit to Santa Fe, you can do some window-shopping at Santa Fe Railyard. Experience the lively festivals and fascinating museums in this romantic area. [](https://expedia.co.uk/Santa-Fe-Railyard-Downtown-Santa-Fe.d553248621533119226.Attraction) ![Santa Fe Plaza which includes heritage architecture, a church or cathedral and street scenes](https://images.trvl-media.com/place/6128782/d6aea3b0-b1ae-4f32-b83f-5a705dcfc3a0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Plaza Home to many landmarks in the heart of the city, this spacious square evokes echoes of the Spanish colonial era with its markets, bandstand and live music. [](https://expedia.co.uk/Santa-Fe-Plaza-Downtown-Santa-Fe.d6128782.Attraction) ![Loretto Chapel showing a church or cathedral](https://images.trvl-media.com/place/502844/7b32c123-0148-4e2e-bb93-62ffcb0886fa.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Loretto Chapel A mysterious spiral staircase with no known origin is the highlight of this former church that now acts as a wedding chapel and museum. [](https://expedia.co.uk/Loretto-Chapel-Downtown-Santa-Fe.d502844.Attraction) ![A peak inside Meow Wolf. Love this place!](https://images.trvl-media.com/place/180028/f96100b6-583d-4452-9af0-e211cc9403ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Meow Wolf You can spend an afternoon studying the exhibits at Meow Wolf during your trip to Santa Fe. Visit the stunning cathedral and shops in this walkable area. [](https://expedia.co.uk/Meow-Wolf-Southside.d553248633953854365.Attraction) ![View of Jemez Mountains from Santa Fe, NM](https://images.trvl-media.com/place/553248621555875014/27fd96a4-3acc-4cf4-9f12-ad53549db70c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ski Santa Fe Hit the slopes at Ski Santa Fe during your trip to Santa Fe. Discover the top-notch restaurants and acclaimed art galleries in this walkable area. [](https://expedia.co.uk/Ski-Santa-Fe-Santa-Fe.d553248621555875014.Attraction) ![Canyon Road showing street scenes](https://images.trvl-media.com/place/6177623/ff96860f-00ca-4167-8244-2ee9f032bfb6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Canyon Road This charming road was once lined with typical adobe residences. Now art galleries, studios, restaurants and boutiques make it the most exclusive part of town. [](https://expedia.co.uk/Canyon-Road-Santa-Fe.d6177623.Attraction) ### Things to do ![Meow Wolf's House of Eternal Return](https://mediaim.expedia.com/localexpert/48942009/c6b32558-401d-44d6-a7f3-b0f650676a21.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Meow Wolf's House of Eternal Return £31 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/meow-wolfs-house-of-eternal-return.a48942009.activity-details) ![Santa Fe: Meow Wolf's House of Eternal Return Ticket](https://mediaim.expedia.com/localexpert/49038609/547e1cc9-1244-4985-97f2-f18394799fcd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe: Meow Wolf The House of Eternal Return Ticket £29 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/santa-fe-meow-wolf-the-house-of-eternal-return-ticket.a49038609.activity-details) ![Santa Fe Self-Guided Walking Audio Tour](https://mediaim.expedia.com/localexpert/47267764/87247edb-6778-4e6e-b528-d86905e14034.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Self-Guided App-Based Walking Audio Tour £11 per traveller **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/santa-fe-self-guided-app-based-walking-audio-tour.a47267764.activity-details) ![Make Your Own Stained Glass Honeycomb](https://mediaim.expedia.com/localexpert/47648896/0d1171aa-223b-4d69-904d-97f46916a7a5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Make Your Own Stained Glass Honeycomb £74 per adult [](https://expedia.co.uk/things-to-do/make-your-own-stained-glass-honeycomb.a47648896.activity-details) ![Santa Fe Revisited](https://mediaim.expedia.com/localexpert/2896714/2cbe1b50-aeac-4e36-8a58-facd7a93acdb.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe Revisited £60 per adult **90%** of travellers recommend [](https://expedia.co.uk/things-to-do/santa-fe-revisited.a2896714.activity-details) ![Tumbleroot Brewery and Distillery Tour and Tasting](https://mediaim.expedia.com/localexpert/5276907/3470e18c-233c-44a4-843b-b6ba2acac370.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tumbleroot Brewery and Distillery Tour and Tasting £13 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/tumbleroot-brewery-and-distillery-tour-and-tasting.a5276907.activity-details) [See all activities in Santa Fe](https://expedia.co.uk/Things-To-Do-In-Santa-Fe.d180028.Travel-Guide-Activities) --- ## Top hotels in Guadalupe District ![Guadalupe Inn](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/fcb94873_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Guadalupe Inn 604 Agua Fria St. Santa Fe NM £78 9 Feb - 10 Feb includes taxes & fees Stay at this hotel in Santa Fe. Enjoy free Wi-Fi, parking (surcharge) and a business centre. Our guests praise the helpful staff in their reviews. Popular attractions ... 9/10 Wonderful! (1,000 reviews) So well located, such hospitality, and such a good price, how could it be so? It was. Thank you for a comfortable room, breakfast and your welcome. Reviewed on 2 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=8806154&PinnedHotelID=8806154&HadPinnedHotel=true®ionId=553248635976481064) ![Perfect downtown location in historic district- 9.5 walk score! Historic home.](https://images.trvl-media.com/lodging/35000000/34120000/34111700/34111637/01a0bf6a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Perfect downtown location in historic district- 9.5 walk score! Historic home. Santa Fe NM Stay at this family-friendly holiday home in Santa Fe. Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Santa Fe Plaza and Santa Fe River ... 9.8/10 Exceptional! (105 reviews) We just loved this place! Totally authentic. Totally centric, yet on a totally quiet residential block. Super comfortable, great kitchen, cozy working fireplace. Outdoor space in front for dining al fresco and in back for BBQ/relaxing. Host is awesome. This is now our new go-to spot in Santa Fe! Reviewed on 17 Jan 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=34111637&PinnedHotelID=34111637&HadPinnedHotel=true®ionId=553248635976481064) [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=34111637&PinnedHotelID=34111637&HadPinnedHotel=true®ionId=553248635976481064) ![La Fonda on the Plaza](https://images.trvl-media.com/lodging/1000000/10000/6700/6690/17bd5948_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Fonda on the Plaza 100 E San Francisco St Santa Fe NM £190 8 Mar - 9 Mar includes taxes & fees Stay at this historic hotel in Santa Fe. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in their ... 9.2/10 Wonderful! (1,094 reviews) The room was lovely, very clean had everything we needed. Every staff member we interacted with was welcoming, helpful, and under standing. We will definitely be back! Reviewed on 1 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=6690&PinnedHotelID=6690&HadPinnedHotel=true®ionId=553248635976481064) ![The Sage Hotel](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/95e1e199_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Sage Hotel 725 Cerrillos Rd Santa Fe NM £58 11 Feb - 12 Feb includes taxes & fees Stay at this business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service and a 24-hour fitness centre. Our guests praise the breakfast and the restaurant ... 7.8/10 Good! (2,203 reviews) Love th location and the breakfast is always great ! Reviewed on 6 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=11%2F02%2F2026&endDate=12%2F02%2F2026&selected=26295&PinnedHotelID=26295&HadPinnedHotel=true®ionId=553248635976481064) ![Inn and Spa at Loretto](https://images.trvl-media.com/lodging/1000000/30000/26300/26264/b1f202d6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Inn and Spa at Loretto 211 Old Santa Fe Trail Santa Fe NM £196 22 Feb - 23 Feb includes taxes & fees Stay at this business-friendly hotel in Santa Fe. Enjoy breakfast (surcharge), a fitness centre and on-site spa services. Our guests praise the restaurant and ... 9/10 Wonderful! (1,001 reviews) What a perfect location! I arrived later than planned and the staff was accommodating and kind. My only wish is that I would have been able to stay longer to enjoy the shops on the property that were closed before my late arrival and early checkout. Reviewed on 4 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=26264&PinnedHotelID=26264&HadPinnedHotel=true®ionId=553248635976481064) ![Drury Plaza Hotel in Santa Fe](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/8f424b4a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel in Santa Fe 828 Paseo de Peralta Santa Fe NM £119 16 Feb - 17 Feb includes taxes & fees Stay at this business-friendly hotel in Santa Fe. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the pool in their reviews. ... 9.4/10 Exceptional! (1,446 reviews) Clean and friendly Great location Good breakfast and happy hour Reviewed on 29 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=16%2F02%2F2026&endDate=17%2F02%2F2026&selected=8199136&PinnedHotelID=8199136&HadPinnedHotel=true®ionId=553248635976481064) [See all 1,670 properties in Guadalupe District](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=09%2F02%2F2026&endDate=10%2F02%2F2026®ionId=553248635976481064) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Guadalupe District hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976481064&startDate=2026-02-08&endDate=2026-02-09)[8 Feb - 9 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976481064&startDate=2026-02-08&endDate=2026-02-09) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976481064&startDate=2026-02-09&endDate=2026-02-10)[9 Feb - 10 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976481064&startDate=2026-02-09&endDate=2026-02-10) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976481064&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976481064&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) --- ### Other neighbourhoods around Guadalupe District ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### West Manhattan West Manhattan might not have many top sights, but Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe are two attractions nearby that you can check out. [](https://expedia.co.uk/Santa-Fe-West-Manhattan.dx553248635976481940) ![A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.](https://images.trvl-media.com/place/180028/cb561ed4-94b9-475c-a214-9227252293c1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Railyard Arts District Art galleries, shopping and spas highlight some of the noteworthy features of Railyard Arts District. Make a stop by Santa Fe Railyard or Santa Fe Farmers Market while you're exploring the neighbourhood. [](https://expedia.co.uk/Santa-Fe-Railyard-Arts-District.dx553248635939577675) ![New Mexico Museum of Art which includes a statue or sculpture and art](https://images.trvl-media.com/place/6064361/7bca942a-dc8a-4a99-b9a7-195e612b2504.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Santa Fe 4.5/5(14 area reviews) Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops and acclaimed art galleries. You might also want to make some time to see Santuario De Nuestra Senora de Guadalupe or Lensic Performing Arts Center while you're exploring the neighbourhood. [](https://expedia.co.uk/Santa-Fe-Downtown-Santa-Fe.dx6054959) ![Delicious vegan and vegetarian options for breakfast and lunch. I had the vegan skillet with green chili and cucumber water #santafe #eats #summer #weekendgetaway](https://images.trvl-media.com/place/180028/2711c99d-30a1-4e3d-b4a0-af40a6e55326.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### West Guadaloupe While West Guadaloupe may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Harrell House of Natural Oddities and Bug Museum and Santuario De Nuestra Senora de Guadalupe. [](https://expedia.co.uk/Santa-Fe-West-Guadaloupe.dx896318469184905216) ![My favorite juice/smoothie/breakfast place in Santa Fe. They also sell general goods and offer lunch. #places #eat #generalgoods #store #goods #flowers #coffee #restaurants #santafe #travel #breakfast #lunch #smoothies #juices #healthy ](https://images.trvl-media.com/place/180028/6726c3ed-7823-41f9-be95-cbeefcf6de11.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Don Diego If you're spending some time in Don Diego, Santa Fe Climbing Gym and Santa Fe Symphony Orchestra and Chorus are top sights worth seeing. [](https://expedia.co.uk/Santa-Fe-Don-Diego.dx896312882680238080) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Casa Solana When in Casa Solana, you can plan a visit to Harrell House of Natural Oddities and Bug Museum and Santuario De Nuestra Senora de Guadalupe, some noteworthy sights in the nearby area. [](https://expedia.co.uk/Santa-Fe-Casa-Solana.dx896325372455632896) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Guadalupe District Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app