Santa Cruz Holidays

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Your Santa Cruz Holiday

Santa Cruz is calling! Whatever type of escape you have in mind, you can see and experience more of this neighbourhood with a Santa Cruz holiday package. Begin your trip to Santa Cruz by checking out nearby attractions such as Pantanal Shopping, Shopping 3 Americas and UFMT Zoo. Don't just imagine it — turn it into reality! Lock in your perfect Santa Cruz holiday with Expedia and experience travel your way.

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
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Centro Político Administrativo

Parks and riverfront are just a few things travellers like about Centro Político Administrativo. A stop by Massairo Okamura Park is also recommended if you've got time to explore the area.

Find hotels in Centro Político Administrativo

Top hotels in Santa Cruz

Amazon Aeroporto Hotel

Amazon Aeroporto Hotel

3 out of 5
Avenida Governador Joao Ponce de Arruda Varzea Grande Mato Grosso
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Amazon Aeroporto Hotel
Delmond Hotel

Delmond Hotel

4 out of 5
Av. Andre Antonio Maggi, 1980 Cuiabá MT
Fully refundableReserve now, pay when you stay
The price is £49 per night from 5 Jun to 6 Jun
£49
5 Jun - 6 Jun
includes taxes & fees
9.2/10 Wonderful! (841 reviews)
"A decade of excellence, though rooms could use a refresh I have been staying at the Delmond for over ten years, and the service remains consistently excellent. The staff is wonderful, the valet service is seamless, and the overall experience is always high-quality. Room is clean and nice. The amenities ..."

Reviewed on 28 Feb 2026

Delmond Hotel
HITS PANTANAL HOTEL AEROPORTO

HITS PANTANAL HOTEL AEROPORTO

3.5 out of 5
Av. Arthur Bernardes, nº 251 Varzea Grande Mato Grosso
Fully refundableReserve now, pay when you stay
The price is £43 per night from 7 Jun to 8 Jun
£43
7 Jun - 8 Jun
includes taxes & fees
HITS PANTANAL HOTEL AEROPORTO
See all 121 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Cruz travel package cost?
We make it easy to travel the world, with Santa Cruz packages starting from just . You'll have the flexibility to bundle your preferred hotels, airlines and car rental. For the ultimate getaway, why not add a few experiences and tours to your travel itinerary?
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Because we understand life is full of surprises, the answer is yes. For more information, check out our Customer Service Portal. But generally speaking, if you've booked your Santa Cruz travel package in the last 24 hours, you may be able to cancel or change it for no charge. Your hotel, airline or car rental company may charge a fee if you made your booking a while ago.
How do I get a cheap travel package to Santa Cruz?
Bundle, bundle, bundle. Hotels, flights and rental cars — combine whatever you need into a Santa Cruz travel package and save. Score even more discounts when you add extras such as tours or experiences to your booking. But that's not the only good part. You have the freedom to tailor your trip your way. We offer more than 550 partner airlines and 1,000,000 hotel options across the world, so that everyone has an opportunity to travel and fulfil those holiday fantasies.
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Yes. Expedia has joined forces with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply pick the payment plan that suits best during the checkout process and take away the stress of budgeting for your next trip. Remember to bundle your accommodation, flights and car hire with Expedia to get the biggest bang for your holiday buck. Browse our flexible payment options below:

  • Pay monthly holidays: Jet off on that dream holiday sooner with Klarna's easy monthly instalment plans. If paying small amounts each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: If you want to pay for your escape across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than all of it upfront) makes it easier to hit that "book now" button, opt for a low deposit holiday payment plan with Klarna.

Where should I stay in Santa Cruz?
If you're eager to be in the middle of the action, stay somewhere close to Arena Pantanal. Many happy campers book a hotel around this awesome attraction.
What are the top hotels in Santa Cruz?
Hotel Gran Odara and Hotel Deville Prime Cuiabá are two of the most popular hotels in Santa Cruz. Why not take a look at the amenities and facilities at each and then decide?
How far in advance should I book my Santa Cruz holiday?
While prices fluctuate, we generally recommend booking your holiday as soon as possible. Most international fares become available on Expedia up to 12 months in advance. If you're booking last minute, you might still be lucky. Discount prices to Santa Cruz sometimes occur just weeks before departure.
What does an Expedia Santa Cruz travel package include?
Car rentals, hotels and flights — we bring you the very best bargains. All you'll have to do is select your favourite combination. Once you've made your booking, you can add on the exciting stuff like activities and tours. Our travel packages make it easy to put together an exciting Santa Cruz getaway.
What should I know before booking a Santa Cruz travel package?
Booking all the parts of your trip together is a smart way to save. Combine your airfares, rental cars and hotels into a convenient little package. But you're not limited to hotels. Expedia features all sorts of properties, including holiday rentals like oceanfront condos and city apartments. You've got choices galore!
Can I choose my airline with a Santa Cruz Expedia travel package?
With a travel package, you're in control. Whether you want to fly to Santa Cruz in economy or first class, simply pick from the available airline options. Expedia has access to more than 550 partner airlines around the world.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.