Title: Santa Cruz Tlaxcala Travel Guide: Best of Santa Cruz Tlaxcala, Tlaxcala Travel 2026 | Expedia.co.uk [Hotels in Santa Cruz Tlaxcala](https://expedia.co.uk/Santa-Cruz-Tlaxcala-Hotels.d553248635640693398.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz Tlaxcala](https://expedia.co.uk/Santa-Cruz-Tlaxcala-Holiday-Rentals.d553248635640693398.Travel-Guide-HolidayRentals)[Santa Cruz Tlaxcala Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Tlaxcala.d553248635640693398.Car-Hire-Guide)[Santa Cruz Tlaxcala Holidays](https://expedia.co.uk/Santa-Cruz-Tlaxcala.d553248635640693398.Holidays-City-Breaks) # Santa Cruz Tlaxcala Travel Guide ## Tourist Guide ## Visit Santa Cruz Tlaxcala - Top hotels in Santa Cruz Tlaxcala - Top Holiday Rentals in Santa Cruz Tlaxcala ![Centro Vacacional IMSS La Trinidad](https://images.trvl-media.com/lodging/127000000/126470000/126469000/126468986/7c77a424_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Centro Vacacional IMSS La Trinidad s/n Del Trabajo Santa Cruz Tlaxcala TLAX £61 9 Apr - 10 Apr includes taxes & fees Stay at this hotel in Santa Cruz Tlaxcala. Enjoy free Wi-Fi, free parking and 3 outdoor pools. Popular attraction Basilica of Ocotlan is located nearby. 2/10 (1 review) El lugar muy bonito, pero las camas terribles y el personal de limpieza terrible Reviewed on 29 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F04%2F2026&endDate=10%2F04%2F2026&selected=126468986&PinnedHotelID=126468986&HadPinnedHotel=true®ionId=553248635640693398) ![Fiesta Inn Parque Puebla](https://images.trvl-media.com/lodging/34000000/34000000/33994500/33994459/0597c8fd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fiesta Inn Parque Puebla Calzada Ignacio Zaragoza, Número 410 Puebla PUE £72 2 Apr - 3 Apr includes taxes & fees Stay at this business-friendly hotel in Puebla. Enjoy breakfast (surcharge), 24-hour room service and a fitness centre. Our guests praise the helpful staff in ... 9.4/10 Exceptional! (858 reviews) Shops nearby, really convenient. Reviewed on 8 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=33994459&PinnedHotelID=33994459&HadPinnedHotel=true®ionId=553248635640693398) ![Holiday Inn Puebla Finsa by IHG](https://images.trvl-media.com/lodging/2000000/1690000/1683700/1683674/e5759a88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Puebla Finsa by IHG Lateral Mexico - Puebla: 7719 Puebla PUE £57 11 Apr - 12 Apr includes taxes & fees Stay at this spa hotel in Puebla. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular attractions ... 9.2/10 Wonderful! (856 reviews) COLD “Hot Tub” - the pool was actually warmer! It was very disappointing since it was the main reason I booked it. Arrived after 12 hour day of driving. Booking came with two free drinks, but we were charged for them. They took them off the bill, but c’mon… Hotel and room were nice, with secure ... Reviewed on 11 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=11%2F04%2F2026&endDate=12%2F04%2F2026&selected=1683674&PinnedHotelID=1683674&HadPinnedHotel=true®ionId=553248635640693398) [See all 225 properties in Santa Cruz Tlaxcala](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=02%2F04%2F2026&endDate=03%2F04%2F2026®ionId=553248635640693398) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Pietro Santo](https://images.trvl-media.com/lodging/85000000/84030000/84020700/84020693/603237c8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pietro Santo Sta Isa Tetlahuaca Km2 San Miguel Xoxtla Santeagueda TLAX Stay at this apartment in Tetlatlahuca. Enjoy free Wi-Fi and a 24-hour front desk. Popular attractions Outlet Puebla Premier and Cacaxtla are located ... [](https://expedia.co.uk/Santeagueda-Hotels-Pietro-Santo.h84020693.Hotel-Information) ![Departamento Romulus](https://images.trvl-media.com/lodging/114000000/113450000/113445600/113445546/c98aaf86_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Departamento Romulus German Blanca Val'Quirico Centro Val'Quirico TLAX Stay at this apartment in Tetlatlahuca. Enjoy free Wi-Fi. Popular attractions Outlet Puebla Premier and Cacaxtla are located nearby. 10/10 Exceptional! (3 reviews) El departamento está muy cómodo y bonito Reviewed on 17 Mar 2026 [](https://expedia.co.uk/Tetlatlahuca-Hotels-Departamento-Romulus.h113445546.Hotel-Information) ![Loft Pienza 6](https://images.trvl-media.com/lodging/113000000/112790000/112786600/112786557/c801faef_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Loft Pienza 6 Val'Quirico Centro, Val'Quirico Val'Quirico TLAX Stay at this apartment in Tetlatlahuca. Enjoy free Wi-Fi and concierge services. Popular attractions Outlet Puebla Premier and Cacaxtla are located nearby. [](https://expedia.co.uk/Tetlatlahuca-Hotels-Loft-Pienza-6.h112786557.Hotel-Information) [See all properties in Santa Cruz Tlaxcala](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635640693398&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Cruz Tlaxcala hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=2026-04-01&endDate=2026-04-02)[1 Apr - 2 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=2026-04-01&endDate=2026-04-02) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=2026-04-02&endDate=2026-04-03)[2 Apr - 3 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=2026-04-02&endDate=2026-04-03) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026)[10 Apr - 12 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640693398&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026) ## Cities near Santa Cruz Tlaxcala ![Group of mexican escaramuza girls with mexican dresses and sombrero riding horses in a line formation](https://images.trvl-media.com/place/6023383/8e0e298a-aadf-4759-8526-83b723f73835.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Apizaco ![Tlaxcala](https://images.trvl-media.com/place/6345209/585eac43-b1ac-45c1-842f-4029642fef07.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Tlaxcala - Cities near Santa Cruz Tlaxcala - Places of interest [Apizaco](https://expedia.co.uk/Apizaco.dx6023383)[Tlaxcala](https://expedia.co.uk/Tlaxcala.dx6345209)[Contla de Juan Cuamatzi](https://expedia.co.uk/Contla-De-Juan-Cuamatzi.dx553248635640657594) - [Fort Loreto ](https://expedia.co.uk/Fort-Loreto-Puebla-Historic-Center.d6302150.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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