Santa Ana Holidays from £323

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to £335 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Packages with flights are ATOL protected

Your Santa Ana Holiday

Our Santa Ana holiday packages give you countless opportunities to enjoy new sights, sounds and flavours. And with all the finer details worked out, you can kick back and enjoy your city adventure without a worry in the world. Make your trip to Santa Ana even more enjoyable by including some sightseeing. Termas de Federacion, Termas Federacion Water Park and Libertad Plaza are some of the most popular attractions worth exploring. Stop daydreaming and start adventuring. Browse the multitude of options on Expedia today and put your Santa Ana holiday plans into gear!

Top Santa Ana Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Smart Guesthouse

Smart Guesthouse

3 out of 5
Rome City Centre
per person
15 Sept - 19 Sept
found 13 hours ago
Return flight included
London (LGW) to Rome (FCO)
9.4/10 Exceptional! (56 reviews)
Good enough for my need. This is not a full service hotel. The bathroom and room are clean and updated, but way too small. Again, the room size is not a big deal because we only use it to sleep.

Reviewed on 14 Aug 2025

Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
per person
26 Oct - 2 Nov
found 1 day ago
Return flight included
London (LCY) to Rome (FCO)
9.6/10 Exceptional! (283 reviews)
Nice room, nice hotel, pretty garden.

Reviewed on 7 Aug 2025

Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
per person
26 Oct - 2 Nov
found 1 day ago
Return flight included
London (LCY) to Rome (FCO)
9.2/10 Wonderful! (549 reviews)
Everything was amazing!! The workers were so sweet and helpful and truly made our stay. The room was extremely quiet for such a busy area. Check in and check out was easy and the room comes with free espresso! We loved everything about our stay and would definitely recommend.

Reviewed on 4 Aug 2025

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
per person
27 Oct - 2 Nov
found 1 day ago
Return direct flight included
London (LCY) to Rome (FCO)
9.4/10 Exceptional! (218 reviews)
Great place to stay, if back in Roma will stay there again!

Reviewed on 1 Aug 2025

The Retreat Collection at 1 Hotel & Homes South Beach

The Retreat Collection at 1 Hotel & Homes South Beach

5 out of 5
South Beach
per person
15 Sept - 22 Sept
found 1 day ago
Return flight included
London (LHR) to Miami (MIA)
8/10 Very Good! (1 review)

Santa Ana Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
2,100
Max Temp Winter
18ºC
Max Temp Summer
32ºC
Top Sights
Termas de Federacion, Termas de Chajarí and Termas Federacion Water Park

Top hotels in Santa Ana

Hotel y Spa Termas del Este

Hotel y Spa Termas del Este

3 out of 5
Presidente Raúl alfonsín 877, Federacion
Fully refundableReserve now, pay when you stay
Muy buena experiencia
"Muy buena experiencia. El hotel no es un lujo, pero es muy comodo, limpio y la atención de la gente excelente."

Reviewed on 25 Nov 2019

Get rates
Hotel y Spa Termas del Este
Totoras Apart Federacion

Totoras Apart Federacion

2.5 out of 5
Ñandubay (ex Hermanas Betancourt) 2610, Federacion, Entre Rios
"Buena estadia para unos dias .todo muy limpio a pesar de que estan aun terminando dptos.tal vez deben cuidar más los horarios de descanso del turista con los ruidos de la obra . Pocos utensilios de cocina si se quiere cocinar ahi mismo.Pero tranquilo y suficiente"

Reviewed on 8 Mar 2023

Get rates
Totoras Apart Federacion
Hotel La Bahia

Hotel La Bahia

2.5 out of 5
San Lorenzo 553, Federacion, Entre Rios (province)
Get rates
Hotel La Bahia
See all 24 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Ana travel package cost?
The cheapest Santa Ana travel package is £323, so your dream escape can become a reality — without burning a hole in your pocket. Combine flights, hotels, car rentals and more to create a package that suits you.
If I'm not able to travel, can I cancel my Santa Ana travel package?
Plans can change in the blink of an eye, so yes, you can. You may be able to cancel or alter your Santa Ana travel package at no cost within 24 hours of booking. For older bookings, you can still cancel or make changes, but your car rental company, hotel or airline may charge a fee. Need more information? Check out our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to Santa Ana?
Combine your bookings with Expedia to save big on your next big adventure. With over 550 partner airlines and 1,000,000 hotels across the globe, your Santa Ana holiday package can be customized exactly to suit your budget. With all that extra money, why not include some awesome tours and activities? It's an easy way to unlock even more discounts. That dream holiday to Santa Ana is much closer than you thought!
Does Expedia offer Book Now, Pay Later Santa Ana holidays?
Expedia has joined forces with online lender Klarna to make booking your next break easier on your hip pocket. Paying in instalments means you can spread the costs of your next adventure, leaving you with more money to play with while you're away. Klarna has several payment plans to pick from, so you're sure to find something that suits your budget. Check out these flexible payment options:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's monthly instalment plans. If making bite-sized repayments each month works for you, choose this option during the checkout process.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your trip across multiple transactions.
  • Low deposit holidays: When you come across an unbeatable deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you get what you want.

What are the top hotels in Santa Ana?
Gran Hotel Paraná and Mayim Hotel Termal & Spa are among the most sought-after properties in Santa Ana. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Ana holiday?
Your best bet is to book early. Airlines usually release flights nearly 12 months ahead of departure, and this is an excellent opportunity to score some of the lowest prices. Boss just told you to take some holiday time next week? That's alright! Expedia are never short of fantastic deals to send you off on the getaway of your dreams, at a price you can afford.
What does an Expedia Santa Ana travel package include?
With Expedia, you can select a combination of car rentals, hotels and flights to build your perfect Santa Ana travel package. Once you've made your booking, you can add on fun stuff like activities and tours. Don't forget — the more you bundle, the more you stand to save!
What should I know before booking a Santa Ana travel package?
You can save a tidy sum by combining your hotels, flights and rental cars. Once you've made your booking, add on fun stuff like day tours or experiences. Your next unforgettable adventure is only a few clicks away.
Can I choose my airline with a Santa Ana Expedia travel package?
You can, and with more than 550 airlines to choose from globally, you have plenty of choice. Have a look through the available options and find out which airline suits your needs and budget.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.