Title: TOP San Luis Obispo Wine Country Spa Hotels for 2026 - Spas in San Luis Obispo Wine Country, CA | Expedia.co.uk [San Luis Obispo Wine Country Travel Guide](https://expedia.co.uk/San-Luis-Obispo-Wine-Country.dx553248621593965865)[Hotels in San Luis Obispo Wine Country](https://expedia.co.uk/San-Luis-Obispo-Wine-Country-Hotels.d553248621593965865.Travel-Guide-Hotels)[Holiday Rentals in San Luis Obispo Wine Country](https://expedia.co.uk/San-Luis-Obispo-Wine-Country-Holiday-Rentals.d553248621593965865.Travel-Guide-HolidayRentals)[Flights to San Luis Obispo Wine Country](https://expedia.co.uk/Cheap-Flights-To-San-Luis-Obispo-Wine-Country.d553248621593965865.Travel-Guide-Flights)[San Luis Obispo Wine Country Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo-Wine-Country.d553248621593965865.Car-Hire-Guide)[San Luis Obispo Wine Country Holidays](https://expedia.co.uk/San-Luis-Obispo-Wine-Country.d553248621593965865.Holidays-City-Breaks) ![#Hiking along the coast of Avila Beach in California. While hiking in this area, BEWARE, because on your left from this spot, is the Nude Beach. Yup, it's the only nude beach that I know of that still exist in California. P.s. It was an accidental find for us, and no, we didn't go. #Waterlust #WeekendGetaway](https://images.trvl-media.com/place/11911/da9298a6-d014-4db2-a780-5eb15f4e4aae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Anthony Hilario # Find Spa Hotels in San Luis Obispo Wine Country, CA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Luis Obispo Wine Country Spa Hotels Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2026-01-11&endDate=2026-01-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2026-01-12&endDate=2026-01-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for San Luis Obispo Wine Country hotels with a spa ![Staircase](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/6f4e12c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Queen Beds | Egyptian cotton sheets, premium bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/a1ad61d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/eb1d5a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/a9f0fa5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila Village Inn [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) Avila Beach 9.2/10 Wonderful (1,002 reviews) "I loved the place - it was classy and homey at the same time. It had a trail leading to the town from the hotel, so charming! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina £107 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) ![Caveman | Bathroom | Shower, hair dryer, bathrobes, towels](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/29ce234c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Madonna Suite | Bathroom | Shower, hair dryer, bathrobes, towels](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/a4e68773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/eaa8a221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) San Luis Obispo 9.2/10 Wonderful (1,346 reviews) "Breakfast & views were amazing! Loved this place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nick £140 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/124000000/123090000/123081300/123081208/5b747aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/124000000/123090000/123081300/123081208/54e56419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/124000000/123090000/123081300/123081208/b701c7d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/124000000/123090000/123081300/123081208/10fd8f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dolphin Bay Resort & Spa [](https://www.expedia.co.uk/Pismo-Beach-Hotels-Dolphin-Bay-Resort-Spa.h123081208.Hotel-Information) Pismo Beach £357 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Pismo-Beach-Hotels-Dolphin-Bay-Resort-Spa.h123081208.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/8a3ff3f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/e0c265d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/94f85976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) Downtown San Luis Obispo 9.2/10 Wonderful (472 reviews) "Staff is horrible and I was charged by Expedia and also the hotel and they’re refusing to refund me " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Demeishia £226 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/1386e090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/74e3dfcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Owners Suite | Living area | 47-inch plasma TV with satellite channels, TV, fireplace](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/86271dbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila La Fonda Hotel [](https://www.expedia.co.uk/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) Avila Beach 9.6/10 Exceptional (1,004 reviews) "From the moment at check-in staff was awesome and the accommodations were great. Great quiet little cali beach town. La Fonda is the right place to stay. One block from the beach as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff £149 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/088fc1a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/3f29ecb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Morro Suite | Living area | 55-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/bdb8f309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Downtown San Luis Obispo 9.4/10 Exceptional (568 reviews) "Great space, friendly staff and good restaurants - we thoroughly enjoyed ourselves. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) michelle £296 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) ![Exclusive Suite, Private Bathroom (PREMIER CALIFORNIA KING - Bay View) | Soundproofing, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/e10d36bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/95bde690.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/70d6de9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Double Room, Private Bathroom (DOUBLE BED - Town View) | Soundproofing, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/b334d90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn at Rose's Landing [](https://www.expedia.co.uk/Morro-Bay-Hotels-Inn-At-Roses-Landing.h116793728.Hotel-Information) Downtown Morro Bay 9.0/10 Wonderful (2 reviews) "Central location Easy parking Clean, newly remodeled room with extensive range of amenities available Staff was extremely friendly and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily £145 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Morro-Bay-Hotels-Inn-At-Roses-Landing.h116793728.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/dea8ddbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/9fba6166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/f7fb843a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) Arroyo Grande 9.6/10 Exceptional (1,001 reviews) "Very nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chritine £115 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Country Roads | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/3769566f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Country Roads | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/799153d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/cd7a3990.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Country Roads | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/12da2465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Geneseo Inn [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-GENESEO-INN.h53975592.Hotel-Information) Paso Robles 10/10 Exceptional (72 reviews) "Great staff, room is wonderful and comfortable, the property and views are amazing" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aleksander £247 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-GENESEO-INN.h53975592.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/d2bd3038.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/3dde3a99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, 1 King Bed, Non Smoking, Ocean View | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/8e1a2a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/10b1b07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayucos Sunset Inn B&B [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) Cayucos 9.8/10 Exceptional (199 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason £153 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26®ionId=553248621593965865&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top San Luis Obispo Wine Country Hotel Reviews ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Our stay was fantastic! We felt welcomed and enjoyed my husband’s birthday in this hotel. Kevin made sure we were comfortable and happy. Will be back! " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Hotel Calle Joaquin](https://images.trvl-media.com/lodging/1000000/900000/891200/891157/d2fc94ff_y.jpg) ### Hotel Calle Joaquin 10/10 Excellent "Excellent " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Rose-Garden-Inn-San-Luis-Obispo.h891157.Hotel-Information) ![Avila Lighthouse Suites](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379138/b29cd20f_y.jpg) ### Avila Lighthouse Suites 10/10 Excellent "We got to check in early, got a room upgraded and staff was very friendly and nice. Lobby was clean and inviting. " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Avila-Lighthouse-Suites.h1379138.Hotel-Information) ![Mission Inn San Luis Obispo](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/f50d5d30_y.jpg) ### Mission Inn San Luis Obispo 10/10 Excellent "Everything was great" [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Mission-Inn-San-Luis-Obispo.h123502.Hotel-Information) ![La Cuesta Inn, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg) ### La Cuesta Inn, BW Signature Collection 10/10 Excellent "Pleasant stay and friendly staff" [](https://expedia.co.uk/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "It was perfect. Cute place and room was great and roomy. Loved the fireplace and it was quiet and quaint. staff are great. Property is close to downtown. " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Sands Inn & Suites](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/b3e0f714_y.jpg) ### Sands Inn & Suites 10/10 Excellent "Great location to stay, will definitely stay again at this location next time " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Sands-Inn-Suites.h2202688.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "great stay, will go again" [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Madonna Inn](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "Beautiful clean room, courteous staff. Long pool hours" [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in San Luis Obispo ](https://www.expedia.co.uk/5Star-San-Luis-Obispo-Hotels.s50-0-d6046822.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Avila Beach ](https://www.expedia.co.uk/Avila-Beach-Hotels-Adults-Only-Resorts.0-0-d11911-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Diamond Resorts in Avila Beach ](https://www.expedia.co.uk/Avila-Beach-Hotels-Diamond-Resorts.0-0-d11911--bDiamondResorts.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Avila Beach ](https://www.expedia.co.uk/Avila-Beach-Hotels-Hotel-With-Free-Parking.0-0-d11911-thotelwithfreeparking.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Avila Beach ](https://www.expedia.co.uk/Avila-Beach-Hotels-Hotels-With-Pool.0-0-d11911-tHotelswithPool.Travel-Guide-Filter-Hotels) - 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