Title: TOP San Luis Obispo Wine Country Spa Hotels for 2025 - Spas in San Luis Obispo Wine Country, CA | Expedia.co.uk [San Luis Obispo Wine Country Travel Guide](https://expedia.co.uk/San-Luis-Obispo-Wine-Country.dx553248621593965865)[Hotels in San Luis Obispo Wine Country](https://expedia.co.uk/San-Luis-Obispo-Wine-Country-Hotels.d553248621593965865.Travel-Guide-Hotels)[Holiday Rentals in San Luis Obispo Wine Country](https://expedia.co.uk/San-Luis-Obispo-Wine-Country-Holiday-Rentals.d553248621593965865.Travel-Guide-HolidayRentals)[Flights to San Luis Obispo Wine Country](https://expedia.co.uk/Cheap-Flights-To-San-Luis-Obispo-Wine-Country.d553248621593965865.Travel-Guide-Flights)[San Luis Obispo Wine Country Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo-Wine-Country.d553248621593965865.Car-Hire-Guide)[San Luis Obispo Wine Country Holidays](https://expedia.co.uk/San-Luis-Obispo-Wine-Country.d553248621593965865.Holidays-City-Breaks) ![San Luis Obispo](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/202000/202822-San-Luis-Obispo.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in San Luis Obispo Wine Country, CA ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Luis Obispo Wine Country Spa Hotels Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-10-10&endDate=2025-10-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-10-11&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top San Luis Obispo Wine Country Spa Hotels ![Caveman | Bathroom | Shower, hair dryer, bathrobes, towels](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/29ce234c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/5a091377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/d6246a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/01a54722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn San Luis Obispo 9.2/10 Wonderful (1268) "such a cool hotel loved the decor and the restaurant is so cool and food was good" £137 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Double Room (Great Room) | Room amenity](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/5728603e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/cd3bd54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Room, 1 King Bed (Spa Room) | Library](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/2d3891c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila La Fonda Hotel Avila Beach 9.6/10 Exceptional (1002) "Very nice hotel. Great for and rest and relaxation kind of vacation" £153 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/18ffa136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/786b3840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/dd32277b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection Downtown San Luis Obispo 9.2/10 Wonderful (460) "We had a great stay" £198 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/f3abfe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Paseo King Room | 1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/0c2ec67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/088fc1a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/88590a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo Downtown San Luis Obispo 9.6/10 Exceptional (530) "Great location. " £279 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/09f8fafa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/af3dfd64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room, 2 Queen Beds | Exterior](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/6a62dfc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/811c4b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Pines Resort Los Osos 8.2/10 Very good (404) "All around an amazing place to stay." £131 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Sea-Pines-Resort.h1839838.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/9e66f2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/3e5ffcce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/4e72b30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection Arroyo Grande 9.6/10 Exceptional (1006) "Great location" £124 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/46c8343c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/57423573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, 1 King Bed, Non Smoking, Ocean View | 1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/8e1a2a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/10b1b07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayucos Sunset Inn B&B Cayucos 9.8/10 Exceptional (190) "Great place to stay" £148 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) ![At Last ADA Compliant | 1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/869d446f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![At Last ADA Compliant | Terrace/patio](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/3062deb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/4a105f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Country Roads | 1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/12da2465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Geneseo Inn Paso Robles 10/10 Exceptional (67) "Relaxing and quiet with beautiful rooms and views. The staff was very helpful." £296 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-GENESEO-INN.h53975592.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=553248621593965865&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top San Luis Obispo Wine Country Hotel Reviews ![Inn at San Luis Obispo](//images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/582169ce_y.jpg) ### Inn at San Luis Obispo 10/10 Excellent "Welcoming " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Inn-At-San-Luis-Obispo.h12356430.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](//images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "Very nice " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Avila Lighthouse Suites](//images.trvl-media.com/lodging/2000000/1380000/1379200/1379138/b29cd20f_y.jpg) ### Avila Lighthouse Suites 10/10 Excellent "Overall it’s a great property to spend a weekend with family. " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Avila-Lighthouse-Suites.h1379138.Hotel-Information) ![Avila Village Inn](//images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/eb1d5a6d_y.jpg) ### Avila Village Inn 10/10 Excellent "Clean room, staff was very friendly. " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) ![Quality Suites Downtown San Luis Obispo](//images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "Nice " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![Madonna Inn](//images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "We stayed in the honeymoon suite and it was definitely worth it" [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Spyglass Inn](//images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f_y.jpg) ### Spyglass Inn 10/10 Excellent "Great location! Comfy beds and clean property! " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Apple Farm](//images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "The staff was very welcoming. The room was nicely furnished, the bed was comfortable and the bathroom clean. The only thing was the room was a little cramped. Other than that everything was great! We would definitely stay at the Apple Farm again." [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Sands Inn & Suites](//images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/b3e0f714_y.jpg) ### Sands Inn & Suites 10/10 Excellent "Why are you forcing me to write this? " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Sands-Inn-Suites.h2202688.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in San Luis Obispo](https://www.expedia.co.uk/5Star-San-Luis-Obispo-Hotels.s50-0-d6046822.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Avila Beach](https://www.expedia.co.uk/Avila-Beach-Hotels-Adults-Only-Resorts.0-0-d11911-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Diamond Resorts in Avila Beach](https://www.expedia.co.uk/Avila-Beach-Hotels-Diamond-Resorts.0-0-d11911--bDiamondResorts.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Avila Beach](https://www.expedia.co.uk/Avila-Beach-Hotels-Hotel-With-Free-Parking.0-0-d11911-thotelwithfreeparking.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Avila Beach](https://www.expedia.co.uk/Avila-Beach-Hotels-Hotels-With-Pool.0-0-d11911-tHotelswithPool.Travel-Guide-Filter-Hotels) - 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[Gay-Friendly Hotels in San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Gay-Friendly-Hotel.0-0-d6046822-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hotels-With-Indoor-Pools.0-0-d6046822-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Luxury Hotels in San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Luxury-Hotel.0-0-d6046822-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oyo Rooms Hotels in San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-OYO-Rooms.0-0-d6046822--bOYORooms.Travel-Guide-Filter-Hotels) - [Winery Hotels in San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Winery-Hotels.0-0-d6046822-tWineryHotels.Travel-Guide-Filter-Hotels) - [San Luis Obispo Hotels](https://www.expedia.co.uk/San-Luis-Obispo-Hotels.d6046822.Travel-Guide-Hotels) - [Motels in San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo-Motels.d6046822-aaMotels.Travel-Guide-Accommodation) - [Sunset Palisades Hotels](https://www.expedia.co.uk/Sunset-Palisades-Pismo-Beach-Hotels.0-n553248635976479350-0.Travel-Guide-Filter-Hotels) - [Flights to Avila Beach](https://www.expedia.co.uk/Cheap-Flights-To-Avila-Beach.d11911.Travel-Guide-Flights) - [Flights to San Luis Obispo](https://www.expedia.co.uk/Cheap-Flights-To-San-Luis-Obispo.d6046822.Travel-Guide-Flights) - [Flights from San Luis Obispo County Regional](https://www.expedia.co.uk/lp/airports/sbp/flights-from-san-luis-obispo-county-regional-airport) - [Delta Detroit (DTW) to San Luis Obispo (SBP) flights](https://www.expedia.co.uk/lp/flight-routes/delta-from-detroit-metropolitan-wayne-county-to-san-luis-obispo-county-regional/dl/dtw/sbp) - [Delta Minneapolis (MSP) to San Luis Obispo (SBP) flights](https://www.expedia.co.uk/lp/flight-routes/delta-from-minneapolis-st-paul-intl-to-san-luis-obispo-county-regional/dl/msp/sbp) - [Delta Phoenix (PHX) to San Luis Obispo (SBP) flights](https://www.expedia.co.uk/lp/flight-routes/delta-from-sky-harbor-intl-to-san-luis-obispo-county-regional/dl/phx/sbp) - [Flights from San Luis Obispo](https://www.expedia.co.uk/lp/flights/6046822/flights-from-san-luis-obispo) - [Flights from Aberdeen (ABZ) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/abz/sbp/aberdeen-to-san-luis-obispo) - [Flights from Birmingham (BHX) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/bhx/sbp/birmingham-to-san-luis-obispo) - [Flights from Basel (BSL) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/bsl/sbp/basel-to-san-luis-obispo) - [Flights from Burbank (BUR) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/bur/sbp/burbank-to-san-luis-obispo) - [Flights from Charleston (CHS) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/chs/sbp/charleston-to-san-luis-obispo) - [Flights from Washington (DCA) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/dca/sbp/washington-to-san-luis-obispo) - [Flights from Denver (DEN) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/den/sbp/denver-to-san-luis-obispo) - [Flights from Edinburgh (EDI) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/edi/sbp/edinburgh-to-san-luis-obispo) - [Flights from Fresno (FAT) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/fat/sbp/fresno-to-san-luis-obispo) - [Flights from Glasgow (GLA) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/gla/sbp/glasgow-to-san-luis-obispo) - [Flights from Houston (IAH) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/iah/sbp/houston-to-san-luis-obispo) - [Flights from New York (JFK) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/jfk/sbp/new-york-to-san-luis-obispo) - [Flights from Las Vegas (LAS) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/las/sbp/las-vegas-to-san-luis-obispo) - [Flights from Los Angeles (LAX) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/lax/sbp/los-angeles-to-san-luis-obispo) - [Flights from London (LCY) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/lcy/sbp/london-to-san-luis-obispo) - [Flights from London (LGW) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/lgw/sbp/london-to-san-luis-obispo) - [Flights from London (LHR) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/lhr/sbp/london-to-san-luis-obispo) - [Flights from Madrid (MAD) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/mad/sbp/madrid-to-san-luis-obispo) - [Flights from Manchester (MAN) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/man/sbp/manchester-to-san-luis-obispo) - [Flights from Massena (MSS) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/mss/sbp/massena-to-san-luis-obispo) - [Flights from Munich (MUC) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/muc/sbp/munich-to-san-luis-obispo) - [Flights from Portland (PDX) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/pdx/sbp/portland-to-san-luis-obispo) - [Flights from Phoenix (PHX) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/phx/sbp/phoenix-to-san-luis-obispo) - [Flights from Palm Springs (PSP) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/psp/sbp/palm-springs-to-san-luis-obispo) - [Flights from San Diego (SAN) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/san/sbp/san-diego-to-san-luis-obispo) - [Flights from Seattle (SEA) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/sea/sbp/seattle-to-san-luis-obispo) - [Flights from San Francisco (SFO) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/sfo/sbp/san-francisco-to-san-luis-obispo) - [Flights from Vancouver (YVR) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/yvr/sbp/vancouver-to-san-luis-obispo) - [Flights from Calgary (YYC) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/yyc/sbp/calgary-to-san-luis-obispo) - [Avila Beach Holidays](https://www.expedia.co.uk/Avila-Beach.d11911.Holidays-City-Breaks) - [Bubblegum Alley](https://www.expedia.co.uk/Bubblegum-Alley-Downtown-San-Luis-Obispo.d553248621532640000.Attraction) - [San Luis Obispo Holidays](https://www.expedia.co.uk/San-Luis-Obispo.d6046822.Holidays-City-Breaks) - [Visit San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo.dx6046822) - [Car hire near Desire Sweet Shoppe](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Desire-Sweet-Shoppe.d553248621532639988.Car-Hire-Guide) - [Rental cars San Luis Obispo County Regional airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo-County-Regional.d6031729.Car-Hire-Guide) - [Car hire San Luis Obispo](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo.d6046822.Car-Hire-Guide) - [San Luis Obispo Holiday Rentals](https://www.expedia.co.uk/San-Luis-Obispo-Holiday-Rentals.d6046822.Travel-Guide-HolidayRentals) - [Things to do in Avila Beach](https://www.expedia.co.uk/Things-To-Do-In-Avila-Beach.d11911.Travel-Guide-Activities) - [Things to do in San Luis Obispo](https://www.expedia.co.uk/Things-To-Do-In-San-Luis-Obispo.d6046822.Travel-Guide-Activities) - [Book Spa Hotels in San Luis Obispo Wine Country on Expedia.com](https://www.expedia.com/San-Luis-Obispo-Wine-Country-Hotels-Spa-Hotel.0-0-d553248621593965865-tSpaHotel.Travel-Guide-Filter-Hotels)