Top Inns in Rochester in 2026

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Recommended hotels in Rochester

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

1. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Arlan

includes taxes & fees

27 Nov - 28 Nov

A spacious outdoor dining area with multiple tables and chairs, large windows, and a wooden ceiling structure.

2. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Kathleen

includes taxes & fees

28 Nov - 29 Nov

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

3. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Tammy

includes taxes & fees

7 Dec - 8 Dec

A modern indoor patio with a fire feature, seating, and large windows.

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

Ashley

includes taxes & fees

27 Nov - 28 Nov

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

5. Kahler Grand Hotel

Downtown Rochester

Kathryn

includes taxes & fees

26 Nov - 27 Nov

A Comfort Inn & Suites hotel with a modern design, featuring a prominent signage and a parking lot.

6. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

LeeAnn

includes taxes & fees

6 Dec - 7 Dec

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

7. Spark by Hilton Rochester South

Rochester

Stanton

includes taxes & fees

22 Nov - 23 Nov

A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

8. Hilton Rochester Mayo Clinic Area

Downtown Rochester

Jennifer

includes taxes & fees

27 Nov - 28 Nov

A modern hotel lobby with a reception desk, seating area, and a dining space.

9. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Rick

includes taxes & fees

14 Nov - 15 Nov

A modern dining area with high tables, chairs, and pendant lighting.

10. Hampton Inn & Suites Rochester-North

Rochester

Mark

includes taxes & fees

28 Nov - 29 Nov

A spacious lobby with a reception desk, sofas, and a coffee table.

11. Sleep Inn & Suites West-Near Medical Center

Rochester

Christopher

includes taxes & fees

28 Nov - 29 Nov

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

12. Comfort Inn & Suites West - Medical Center

Rochester

Tammy

includes taxes & fees

28 Nov - 29 Nov

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

13. Econo Lodge Mayo Clinic Area

Rochester

Lorraine

includes taxes & fees

4 Dec - 5 Dec

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

14. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

howard

includes taxes & fees

29 Nov - 30 Nov

A garden with a water feature, rocks, and yellow umbrellas.

15. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

Deanna

includes taxes & fees

13 Nov - 14 Nov

A modern living room with a fireplace, comfortable seating, and large windows.

16. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park

Sheri

includes taxes & fees

26 Nov - 27 Nov

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

17. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester

Richard

includes taxes & fees

13 Nov - 14 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

18. Quality Inn & Suites Mayo Clinic Area

Rochester

Mark

includes taxes & fees

28 Nov - 29 Nov

A Holiday Inn Express building with a covered entrance, outdoor seating area, and a well-lit facade.

19. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Kutzky Park

Laura

includes taxes & fees

14 Nov - 15 Nov

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

20. Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester

Li

includes taxes & fees

4 Dec - 5 Dec

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Top Rochester Hotel Reviews

Kahler Grand Hotel

10/10 Excellent

"The Kahlers had ties to the Mayos and the clinic going back a century. It is perfectly located on the skyway across the street and skyway from the clinic’s Gonda building, near Methodist hospital, and about four skyway blocks to the Civic Center. The subway walkways will also cover most of the Mayo complex It is not close to St Mary’s hospital, which is about a mile west near hwy 52. For drivers the worst feature is pricy - $34/night for valet parking, and $18-24(?)/night for city ramps. So price that in compared to motels with or hotels with free parking. Few if any. Are as convenient, but many have circulating shuttles, though not at night if you a medically unstable family member. The building may be pre-war. It’s in good shape. A basic room is of modest size,, with a comfortable bed, hotel services and room service - which counts for those there for seriously ill patients. The hotel restaurant has reasonable prices, and there are sandwich and taco shops downstairs."

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"We stayed for 2 nights going to the Mayo clinic. They offer a shuttle which is very nice even though we didn't use it. The hot tub was not hot so we didn't get to use it. The restaurant was very nice to have right there and we ate there several times. The room was decent. The beds were great. Breakfast wasn't great but ok. Coffee is terrible. Great location. There's things kinda all over the hotel that needed help and fixing. The staff was awesome. Pets are allowed and a little dog barked all morning so that was ridiculous. Otherwise we'd stay again and ask to not be by any pet rooms"

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"My one complaint is the lack of sufficient AC outlets near the beds. There was a single duplex outlet between the beds that had a lamp and an alarm clock plugged in. There was no way to plug in my CPAP machine without unplugging the clock. A simple solution would be to use a table lamp with additional AC outlets as I have seen in other hotels."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"The staff was friendly and helpful: The rooms are well appointed (good size refrigerator, coffee maker, silverware), clean and spacious. The bed and pillows were very comfortable! Breakfast was pretty average fare. The coffee is pretty cheap. Other than that, we loved everything about the hotel. We would stay here again when visiting the Mayo Clinic."

Holiday Inn Express Rochester South - Mayo Area by IHG

10/10 Excellent

"The first room we were given did not have a working AC unit nor a working landline phone to call the desk. (Walking down to talk to the gal at the desk was easy, I just found it humorous that I couldn’t call her from the room. The second room we were given was awesome! And breakfast was great (pancake machine, omelets, biscuits and gravy, etc) I would stay here again if we are in the area."

Find out more about Rochester

Rochester Inns information

Number of reviews	14,154
Accommodation	0 Inns
Lowest Price	£57
Highest Price	£145

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Recommended hotels in Rochester

1. Hyatt House Rochester/Mayo Clinic Area

2. Hotel Indigo Rochester – Mayo Clinic Area by IHG

3. AmericInn by Wyndham Rochester Near Mayo Clinic