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Recommended hotels in Rochester

1. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,006 reviews)
"Great stay."
Canada
Robert Blaise
The price is £96
includes taxes & fees
27 Nov - 28 Nov
Hyatt House Rochester/Mayo Clinic Area

2. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,004 reviews)
"This was a nice hotel with a great location. There were several bars and restaurants within walking distance."
United States
Kathleen
The price is £89
includes taxes & fees
14 Nov - 15 Nov
Hotel Indigo Rochester – Mayo Clinic Area by IHG

3. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,002 reviews)
"Nice location, easy access and good breakfast."
United States
Rick
The price is £71
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express Rochester South - Mayo Area by IHG

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (1,013 reviews)
"Very nice, well kept, comfy beds, nice staff"
United States
Ashley
The price is £105
includes taxes & fees
27 Nov - 28 Nov
EVEN Hotel Rochester - Mayo Clinic Area by IHG

5. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,005 reviews)
"Clean room great facilities."
United States
Mark
The price is £84
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn & Suites Rochester-North

6. Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very good, (2,407 reviews)
"We love the pool and hot tub!"
United States
Kathryn
The price is £119
includes taxes & fees
26 Nov - 27 Nov
Kahler Grand Hotel

7. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very good, (1,603 reviews)
"Was a quick and comfortable stay."
United States
Tammy
The price is £63
includes taxes & fees
6 Dec - 7 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic

8. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (1,009 reviews)
"This was a very nice place to stay. It felt cozy, warm.... walking distance to a Perkins. Loved it."
United States
Lorraine
The price is £58
includes taxes & fees
4 Dec - 5 Dec
Econo Lodge Mayo Clinic Area

9. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (656 reviews)
"Clean rooms, great staff, convenient location."
United States
Jennifer
The price is £146
includes taxes & fees
27 Nov - 28 Nov
Hilton Rochester Mayo Clinic Area

10. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,009 reviews)
"Great place to stay."
United States
LeeAnn
The price is £65
includes taxes & fees
11 Dec - 12 Dec
Comfort Inn & Suites Rochester South Mayo Clinic

11. Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
Rochester
9.0 out of 10, Wonderful, (727 reviews)
"Just a pleasant hotel a few hours from NYC"
United States
Christopher
The price is £67
includes taxes & fees
6 Dec - 7 Dec
Sleep Inn & Suites West-Near Medical Center

12. Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
3.0 star property
Rochester
8.8 out of 10, Excellent, (669 reviews)
"The room was very clean and the beds were comfortable. Breakfast was good with lots of options."
United States
Tammy
The price is £71
includes taxes & fees
11 Dec - 12 Dec
Comfort Inn & Suites West - Medical Center

13. Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (607 reviews)
"Clean room Staff very accommodating Hot coffee and breakfast."
United States
Stanton
The price is £58
includes taxes & fees
22 Nov - 23 Nov
Spark by Hilton Rochester South

14. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (1,002 reviews)
"Clean room, very nice staff and nice atmosphere."
United States
howard
The price is £96
includes taxes & fees
29 Nov - 30 Nov
Home2 Suites by Hilton Rochester Mayo Clinic Area

15. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.6 out of 10, Excellent, (850 reviews)
"The staff was super helpful and friendly. My room felt quite clean. The continental breakfast was above average. Really no complaints and I would stay again."
United States
Laura
The price is £87
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

16. Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.2 out of 10, Very good, (1,718 reviews)
"very good place!"
United States
Li
The price is £117
includes taxes & fees
10 Dec - 11 Dec
Kahler Inn and Suites - Mayo Clinic Area

17. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1,018 reviews)
"Beautiful place to stay"
United States
Deanna
The price is £98
includes taxes & fees
14 Nov - 15 Nov
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

18. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (753 reviews)
"The staff was extremely helpful making for a comfortable stay."
United States
Brien
The price is £96
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

19. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (563 reviews)
"Love love this hotel! Perfect for patients at Mayo and family"
United States
Amanda
The price is £92
includes taxes & fees
25 Nov - 26 Nov
Staybridge Suites Rochester - Mayo Clinic Area by IHG

20. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (576 reviews)
"Excellent service, room was great and the lobby area is great for hanging out in the evenings!"
Canada
Cory
The price is £118
includes taxes & fees
14 Nov - 15 Nov
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Rochester and related destinations

Home to the world-famous Mayo Clinic, this city offers surprising cultural richness with its vibrant city centre art scene and Plummer Building tours. Explore the peaceful Quarry Hill Nature Centre trails in morning hours, then sample local craft beers at one of the breweries along Historic 3rd Street.

A cityscape at dusk with a river reflecting lights, modern buildings, and a bridge.