Puerto Santa Ana Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Puerto Santa Ana Holiday

With plenty of highlights as well as some hidden gems, this city is best experienced with a Puerto Santa Ana holiday package. Find somewhere to stay in Downtown Guayaquil, which is good for views, culture and history. Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Centre are just a few of the many attractions you'll want to see during your trip to Puerto Santa Ana. Whoever you're taking time off with and whatever you plan to spend, your ultimate Puerto Santa Ana holiday is just a few clicks away with Expedia.

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador
A statue of a soldier on a pedestal with a building in the background.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

Find hotels in Downtown Guayaquil
A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Find hotels in Kennedy
A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or Santa Ana Port.

Find hotels in Urdesa
A cityscape with a prominent skyscraper, a river, and a bridge.

Simón Bolívar

1 out of top 10 points of interest in this area

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

Find hotels in Simón Bolívar

Top hotels in Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N Guayaquil Guayas
£91
6 Sept - 7 Sept
9.2/10 Wonderful! (1,000 reviews)
"Muy bueno siempre"

Reviewed on 12 Aug 2026

Wyndham Guayaquil Puerto Santa Ana
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

Puerto Santa Ana Guayaquil Guayas
£62
14 Sept - 15 Sept
Luxury Suites Riverfront GYE
Modern 2 BR Apt on the 14th floor includes Parking

Modern 2 BR Apt on the 14th floor includes Parking

Guayaquil Guayas
Get rates
Modern 2 BR Apt on the 14th floor includes Parking
See all 448 properties in Puerto Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays
Golf Holidays
Golf Holidays
Luxury Holidays
Luxury Holidays
gay friendly holidays
LGBTQ+ Holidays
LGBTQ+ Holidays
Romantic Holidays
Romantic Holidays
Ski Holidays
Ski Holidays
Pet Friendly Holidays
Pet Friendly Holidays
Holiday in Month
Where to go when
Where to go when

Frequently asked questions

How much does a Puerto Santa Ana travel package cost?
Perhaps less than you imagined — from only , as a matter of fact! By bundling hotels, flights and car rentals into your own tailor-made travel package, your Puerto Santa Ana escape is just clicks away.
If I'm not able to travel, can I cancel my Puerto Santa Ana travel package?
Don't stress if you're rethinking your Puerto Santa Ana travel package — it's possible to cancel or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We understand life can sometimes throw you a curveball, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.
How do I get a cheap travel package to Puerto Santa Ana?
It's easy. Just bundle everything together. Flights, rental cars and hotels — combine whatever you need into a Puerto Santa Ana travel package to save a pile of cash. Score even more discounts when you include extras such as tours or experiences to your booking. But that's not the only good part. You have the flexibility to customize your trip your way. We offer over 550 airlines and 1,000,000 hotels across the globe, so that everyone has an opportunity to travel and live out those holiday dreams.
Does Expedia offer Book Now, Pay Later Puerto Santa Ana holidays?
Yes. Expedia has partnered with online lender Klarna to help you conveniently pay for your trip in instalments. Simply select the payment plan best suited to your needs during the checkout process and take the stress out of budgeting for your trip. Don't forget to bundle your flights, car hire and accommodation with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:
  • Pay monthly holidays: Klarna offers easy monthly payment plans that work for all budget sizes, so you can escape on that well-earned holiday now.
  • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Then select this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: When you see an unbeatable deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you secure your getaway.
Where should I stay in Puerto Santa Ana?
A getaway to Puerto Santa Ana wouldn't be complete without paying a visit to Malecon 2000, Mall del Sol Commercial Centre and Clock Tower. Spend your nights close to these popular attractions and make sightseeing easy.
What are the top hotels in Puerto Santa Ana?
Wyndham Guayaquil, Puerto Santa Ana and Oro Verde Guayaquil are two of the most well-known hotels in Puerto Santa Ana. Why not take a look at the facilities and rates at each and then make a decision?
How far in advance should I book my Puerto Santa Ana holiday?
Savvy travellers book early. Air carriers generally release flights up to a year in advance, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you need to take your holiday time next month? That's fine too — Expedia are never short on fantastic bargains to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Puerto Santa Ana travel package include?
It all boils down to what sort of escape you have in mind. Puerto Santa Ana holiday deals can include car rentals, flights and hotels. You can mix and match to find the travel package that suits your needs. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking a Puerto Santa Ana travel package?
When you book your hotels, flights and car rentals together, you'll be rewarded with great discounts. Whether you're organising a wilderness getaway in a cabin or would rather stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Puerto Santa Ana Expedia travel package?
With a travel package, you're the one in charge. Whether you're eager to fly to Puerto Santa Ana in economy or first class, simply pick from the available airline options. Expedia has access to more than 550 partner airlines globally.

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

£92
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Private city tour in Guayaquil - Iguana Park

Guayaquil Premium City Tour - Best Spots

£113
per adult
Guayaquil Premium City Tour - Best Spots
Guayaquil City Tour Including the Light House of Cerro Santa Ana

Guayaquil City Tour Including the Light House of Cerro Santa Ana

£105
per adult
Guayaquil City Tour Including the Light House of Cerro Santa Ana
See all activities in Guayaquil

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.