Title: Puerto Santa Ana Holidays 2026 | Expedia.co.uk [Puerto Santa Ana Travel Guide](https://expedia.co.uk/Guayaquil-Puerto-Santa-Ana.dx6338310)[Hotels in Puerto Santa Ana](https://expedia.co.uk/Puerto-Santa-Ana-Guayaquil-Hotels.0-n6338310-0.Travel-Guide-Filter-Hotels)[Flights to Guayaquil](https://expedia.co.uk/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights)[Things to do in Guayaquil](https://expedia.co.uk/Things-To-Do-In-Guayaquil.d1414.Travel-Guide-Activities)[Puerto Santa Ana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Puerto-Santa-Ana.d6338310.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6338310/7d2e991e-9428-4fdb-b585-549f29a51fa9.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Puerto Santa Ana Holidays ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your Puerto Santa Ana Holiday With plenty of highlights as well as some hidden gems, this city is best experienced with a Puerto Santa Ana holiday package. Find somewhere to stay in Downtown Guayaquil, which is good for views, culture and history. [Malecon 2000](https://www.expedia.co.uk/Malecon-2000-Guayaquil.d6112432.Attraction), [Banco Pichincha Monumental Stadium](https://www.expedia.co.uk/Banco-Pichincha-Monumental-Stadium-Guayaquil.d6112418.Attraction) and [Mall del Sol Commercial Centre](https://www.expedia.co.uk/Mall-Del-Sol-Commercial-Center-Simon-Bolivar.d6160670.Attraction) are just a few of the many attractions you'll want to see during your trip to Puerto Santa Ana. Whoever you're taking time off with and whatever you plan to spend, your ultimate Puerto Santa Ana holiday is just a few clicks away with Expedia. ## Where to stay in Puerto Santa Ana Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. [Learn more about Puerto Santa Ana](https://expedia.co.uk/Guayaquil-Puerto-Santa-Ana.dx6338310) ![Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador](https://images.trvl-media.com/place/553248635976397513/63317c37-23f5-4437-8dce-9baf7ec279e3.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Ecuador Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out. [Find hotels in Ecuador](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248635976397513) ![Important monument here in Guayaquil ](https://images.trvl-media.com/place/6337570/ec818446-c148-43bd-834f-eee037c6cfc5.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Guayaquil Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town. [Find hotels in Downtown Guayaquil](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6337572) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Bolívar While Bolívar may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like George Capwell Stadium and Central Market. [Find hotels in Bolívar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=916425151487365120) ![Iguanas at Seminario Park](https://images.trvl-media.com/place/553248633981744847/d4310477-b1ec-4eb2-b80d-45aebf42e40d.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Urdesa Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall. [Find hotels in Urdesa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248633981744847) ![Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.](https://images.trvl-media.com/place/553248633981744623/4b429326-1b45-4f96-a199-253791852ff3.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Kennedy 1 out of top 10 points of interest in this area Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area. [Find hotels in Kennedy](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248633981744623) ## Top hotels in Puerto Santa Ana ![Wyndham Guayaquil Puerto Santa Ana](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham Guayaquil Puerto Santa Ana Calle Numa Pompilio Llona S N Guayaquil Guayas Fully refundableReserve now, pay when you stay £75 17 Feb - 18 Feb 9.2/10 Wonderful! (1,005 reviews) Staff was very friendly, food spectacular, and the infrastructure was amazing! Spa was a plus... Reviewed on 5 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=6312483&PinnedHotelID=6312483&HadPinnedHotel=true®ionId=6338310) ![Luxury Suites Riverfront GYE](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/42319f76_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Luxury Suites Riverfront GYE Puerto Santa Ana Guayaquil Guayas £82 19 Feb - 20 Feb 9.2/10 Wonderful! (104 reviews) La habitación estaba muy limpia excelente suite Reviewed on 25 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=32048032&PinnedHotelID=32048032&HadPinnedHotel=true®ionId=6338310) ![River View suites Puerto Santa Ana gye](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/b3ec1eca_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### River View suites Puerto Santa Ana gye Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas Fully refundableReserve now, pay when you stay £60 10 Feb - 11 Feb 8.6/10 Excellent! (46 reviews) Excellent Reviewed on 15 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=10%2F02%2F2026&endDate=11%2F02%2F2026&selected=22652575&PinnedHotelID=22652575&HadPinnedHotel=true®ionId=6338310) [See all 421 properties in Puerto Santa Ana](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=10%2F02%2F2026&endDate=11%2F02%2F2026®ionId=6338310) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Frequently asked questions ### How much does a Puerto Santa Ana travel package cost? ### If I'm not able to travel, can I cancel my Puerto Santa Ana travel package? ### How do I get a cheap travel package to Puerto Santa Ana? ### Does Expedia offer Book Now, Pay Later Puerto Santa Ana holidays? > - Pay monthly holidays: Klarna offers easy monthly payment plans that work for all budget sizes, so you can escape on that well-earned holiday now. > - Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Then select this Book Now, Pay Later option with Klarna. > - Low deposit holidays: When you see an unbeatable deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you secure your getaway. ### Where should I stay in Puerto Santa Ana? ### What are the top hotels in Puerto Santa Ana? ### How far in advance should I book my Puerto Santa Ana holiday? ### What does an Expedia Puerto Santa Ana travel package include? ### What should I know before booking a Puerto Santa Ana travel package? ### Can I choose my airline with a Puerto Santa Ana Expedia travel package? ### Popular places to visit #### Dr. Teodoro Maldonado Carbo Hospital If Dr. Teodoro Maldonado Carbo Hospital is what brings you to town, hopefully you'll have a chance to explore more of Guayaquil. [](https://expedia.co.uk/Dr-Teodoro-Maldonado-Carbo-Hospital-Guayaquil.d6331051.Attraction) ### Things to do ![Half Day Walking Tour of Guayaquil Pearl of the Pacific](https://mediaim.expedia.com/localexpert/44847268/e9f87071-a55f-439d-b9b9-b5b419c4838c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Half Day Walking Tour of Guayaquil Pearl of the Pacific £74 per adult [](https://expedia.co.uk/things-to-do/half-day-walking-tour-of-guayaquil-pearl-of-the-pacific.a44847268.activity-details) ![Making hot Chocolate!](https://mediaim.expedia.com/localexpert/1750558/510bf7ee-5365-4f56-b4a2-cb0eec4c6e29.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cocoa farm and Chocolate making! £115 per adult [](https://expedia.co.uk/things-to-do/cocoa-farm-and-chocolate-making.a1750558.activity-details) ![Santa Ana Hill](https://mediaim.expedia.com/localexpert/2388931/0a2d875f-ff49-4c4c-bfee-b451b136722b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Guayaquil City Tour Including the Light House of Cerro Santa Ana £104 per adult [](https://expedia.co.uk/things-to-do/guayaquil-city-tour-including-the-light-house-of-cerro-santa-ana.a2388931.activity-details) [See all activities in Guayaquil](https://expedia.co.uk/things-to-do/search?rid=6338310) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.