Puerto Santa Ana Holidays from £1,313

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Your Puerto Santa Ana Holiday

With plenty of highlights as well as some hidden gems, this city is best experienced with a Puerto Santa Ana holiday package. Find somewhere to stay in Downtown Guayaquil, which is good for views, culture and history. Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Centre are just a few of the many attractions you'll want to see during your trip to Puerto Santa Ana. Whoever you're taking time off with and whatever you plan to spend, your ultimate Puerto Santa Ana holiday is just a few clicks away with Expedia.

Price found within the past 48 hours. Click for updated prices.
Hotel Presidente Internacional

Hotel Presidente Internacional

3.5 out of 5
Downtown Guayaquil
Price was £1,405, price is now £1,313 per person
£1,313
per person
11 Jul - 17 Jul
found 1 day ago
Return flight included
Manchester (MAN) to Guayaquil (GYE)
6.4/10 (31 reviews)
Nos gustó mucho limpio

Reviewed on 24 Feb 2026

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5
Las Peñas
Price was £2,618, price is now £2,004 per person
£2,004
per person
11 Jul - 17 Jul
found 1 day ago
Return flight included
Manchester (MAN) to Guayaquil (GYE)
10/10 Exceptional! (3 reviews)
The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work.

Reviewed on 25 Oct 2025

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana
Price was £1,514, price is now £1,414 per person
£1,414
per person
11 Jul - 17 Jul
found 1 day ago
Return flight included
Manchester (MAN) to Guayaquil (GYE)
9.4/10 Exceptional! (106 reviews)
Amazing stay. The apartment is beautiful, comfortable, and feels truly luxurious. .The location made everything even better. There’s a great market, pharmacy, and excellent restaurants just steps away. It made the whole stay very convenient, and I didn’t need to go anywhere else. Highly recommend.

Reviewed on 16 Apr 2026

Hotel Marcelius

Hotel Marcelius

3.5 out of 5
Kennedy
Price was £1,474, price is now £1,388 per person
£1,388
per person
11 Jul - 17 Jul
found 1 day ago
Return flight included
Manchester (MAN) to Guayaquil (GYE)
8.2/10 Very Good! (237 reviews)
AC kept the room cool but it was a little noisy. Nice big bathroom but water flow in the shower was very low.

Reviewed on 11 Apr 2026

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil

5 out of 5
Kennedy
Price was £1,524, price is now £1,439 per person
£1,439
per person
11 Jul - 17 Jul
found 1 day ago
Return flight included
Manchester (MAN) to Guayaquil (GYE)
9.2/10 Wonderful! (678 reviews)
La comodidad de las habitaciones , y la isonaracionnde las mismas hacen de este hotel ser muy recomendable, además del desayuno muy completo y la amabilidad del staff en todo momento.

Reviewed on 18 Apr 2026

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador

Top hotels in Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is £75 per night from 2 May to 3 May
£75
2 May - 3 May
9.2/10 Wonderful! (1,004 reviews)
Clean room

Reviewed on 20 Apr 2026

Wyndham Guayaquil Puerto Santa Ana
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana Guayaquil Guayas
The price is £69 per night from 1 May to 2 May
£69
1 May - 2 May
9.4/10 Exceptional! (107 reviews)
Amazing stay. The apartment is beautiful, comfortable, and feels truly luxurious. .The location made everything even better. There’s a great market, pharmacy, and excellent restaurants just steps away. It made the whole stay very convenient, and I didn’t need to go anywhere else. Highly ...

Reviewed on 16 Apr 2026

Luxury Suites Riverfront GYE
River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye

3 out of 5
Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is £55 per night from 8 May to 9 May
£55
8 May - 9 May
8.8/10 Excellent! (51 reviews)
Beautiful apartment suite very safe close ally restaurant next a 24 pharmacy ac worked perfectly fine pool was beautiful and refreshing

Reviewed on 23 Apr 2026

River View suites Puerto Santa Ana gye
See all 432 properties in Puerto Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Puerto Santa Ana travel package cost?
Perhaps less than you imagined — from only £1,313, as a matter of fact! By bundling hotels, flights and car rentals into your own tailor-made travel package, your Puerto Santa Ana escape is just clicks away.
If I'm not able to travel, can I cancel my Puerto Santa Ana travel package?
Don't stress if you're rethinking your Puerto Santa Ana travel package — it's possible to cancel or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We understand life can sometimes throw you a curveball, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.
How do I get a cheap travel package to Puerto Santa Ana?
It's easy. Just bundle everything together. Flights, rental cars and hotels — combine whatever you need into a Puerto Santa Ana travel package to save a pile of cash. Score even more discounts when you include extras such as tours or experiences to your booking. But that's not the only good part. You have the flexibility to customize your trip your way. We offer over 550 airlines and 1,000,000 hotels across the globe, so that everyone has an opportunity to travel and live out those holiday dreams.
Does Expedia offer Book Now, Pay Later Puerto Santa Ana holidays?
Yes. Expedia has partnered with online lender Klarna to help you conveniently pay for your trip in instalments. Simply select the payment plan best suited to your needs during the checkout process and take the stress out of budgeting for your trip. Don't forget to bundle your flights, car hire and accommodation with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: Klarna offers easy monthly payment plans that work for all budget sizes, so you can escape on that well-earned holiday now.
  • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Then select this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: When you see an unbeatable deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you secure your getaway.

Where should I stay in Puerto Santa Ana?
A getaway to Puerto Santa Ana wouldn't be complete without paying a visit to Malecon 2000, Mall del Sol Commercial Centre and Clock Tower. Spend your nights close to these popular attractions and make sightseeing easy.
What are the top hotels in Puerto Santa Ana?
Wyndham Guayaquil, Puerto Santa Ana and Oro Verde Guayaquil are two of the most well-known hotels in Puerto Santa Ana. Why not take a look at the facilities and rates at each and then make a decision?
How far in advance should I book my Puerto Santa Ana holiday?
Savvy travellers book early. Air carriers generally release flights up to a year in advance, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you need to take your holiday time next month? That's fine too — Expedia are never short on fantastic bargains to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Puerto Santa Ana travel package include?
It all boils down to what sort of escape you have in mind. Puerto Santa Ana holiday deals can include car rentals, flights and hotels. You can mix and match to find the travel package that suits your needs. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking a Puerto Santa Ana travel package?
When you book your hotels, flights and car rentals together, you'll be rewarded with great discounts. Whether you're organising a wilderness getaway in a cabin or would rather stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Puerto Santa Ana Expedia travel package?
With a travel package, you're the one in charge. Whether you're eager to fly to Puerto Santa Ana in economy or first class, simply pick from the available airline options. Expedia has access to more than 550 partner airlines globally.

Popular places to visit

Dr. Teodoro Maldonado Carbo Hospital

If Dr. Teodoro Maldonado Carbo Hospital is what brings you to town, hopefully you'll have a chance to explore more of Guayaquil.

Dr. Teodoro Maldonado Carbo Hospital

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

£89
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Best of Guayaquil - City Tour

Premium City Tour for Seniors - Guayaquil

£111
per adult
Premium City Tour for Seniors - Guayaquil
Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

£74
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
See all activities in Guayaquil

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.