A sunset over a calm lake with red autumn leaves on the right.

Search Holiday Homes in Poplar Bluff

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
2 Oct - 4 Oct
In two months
13 Nov - 15 Nov
In three months
11 Dec - 13 Dec
In four months
8 Jan - 10 Jan

Our top choices for Poplar Bluff holiday homes

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

1. 40-Acre Poplar Bluff Nature Lovers Paradise!

40-Acre Poplar Bluff Nature Lovers Paradise!
Poplar Bluff
9.4 out of 10, Exceptional, (34 reviews)
"It was perfect for our family "
United States
Elsie C.
The price is £219
includes taxes & fees
7 Oct - 8 Oct
40-Acre Poplar Bluff Nature Lovers Paradise!
A house with a front porch decorated with hay bales, a scarecrow, and pumpkins.

2. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
8.8 out of 10, Excellent, (15 reviews)
"House was great. Will definitely be back."
United States
Anonymous traveller
The price is £216
includes taxes & fees
20 Sept - 21 Sept
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

3. Cozy 2-bedroom house in welcoming Poplar Bluff

Cozy 2-bedroom house in welcoming Poplar Bluff
Poplar Bluff
6.8 out of 10, (3 reviews)
"This property suited our needs just fine for an overnight stay on the way to Louisville."
United States
Carrie H.
The price is £151
includes taxes & fees
16 Sept - 17 Sept
Cozy 2-bedroom house in welcoming Poplar Bluff
A modern kitchen with white cabinets, stainless steel appliances, a central island with stools, and a hanging pendant light.

4. Poplar Bluff pet friendly comfort and convenience

Poplar Bluff pet friendly comfort and convenience
Poplar Bluff
The price is £457
includes taxes & fees
16 Sept - 17 Sept
Poplar Bluff pet friendly comfort and convenience
A campfire surrounded by benches in a wooded park area.

5. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
10.0 out of 10, Exceptional, (1 review)
"Very cozy"
United States
Shea E.
The price is £172
includes taxes & fees
16 Sept - 17 Sept
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
A wooden deck with steps leading to a house, surrounded by trees.

6. Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (100 reviews)
"Gorgeous property, wonderful hosts. Would love to visit again "
United States
Anonymous traveller
The price is £100
includes taxes & fees
16 Sept - 17 Sept
Get Away Acres 1/2 mile off highway 60 extra sanitized
A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

7. Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
The price is £189
includes taxes & fees
16 Sept - 17 Sept
Hunting / Fishing Cabin at Lake Wappapello
A cozy living room with two leather sofas, a stone wall, wooden ceiling, and a large sliding glass door leading to an outdoor deck.

8. Doc's Cottage - A-Frame in Piggott, AR

Doc's Cottage - A-Frame in Piggott, AR
Piggott
10.0 out of 10, Exceptional, (15 reviews)
"A comfortable place to visit in my home town and catch up with local family members."
United States
Mary C.
The price is £183
includes taxes & fees
22 Sept - 23 Sept
Doc's Cottage - A-Frame in Piggott, AR
A two-story house with a front porch, a covered entryway, and a small garden with white flowers.

9. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
8.0 out of 10, Very good, (36 reviews)
"This was very convenient for our group - thank you!"
United States
Kathryn T.
The price is £160
includes taxes & fees
21 Sept - 22 Sept
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
A modern kitchen with white cabinets, a marble island, and stainless steel appliances.

10. Scotty's sunny spot

Scotty's sunny spot
Doniphan
10.0 out of 10, Exceptional, (12 reviews)
"Beautiful home, comfortable, and convenient to everything"
United States
Mickey S.
The price is £299
includes taxes & fees
16 Sept - 17 Sept
Scotty's sunny spot
A modern kitchen with stainless steel appliances, wooden cabinets, and a white countertop.

11. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
The price is £122
includes taxes & fees
16 Sept - 17 Sept
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
A modern kitchen with a central island, bar stools, stainless steel appliances, and wooden flooring.

12. The Morning Glory - Country Cottage

The Morning Glory - Country Cottage
Piggott
10.0 out of 10, Exceptional, (9 reviews)
"House was clean and had everything we needed for a comfortable stay!"
United States
Justin C.
The price is £192
includes taxes & fees
16 Sept - 17 Sept
The Morning Glory - Country Cottage
A wooden dock extending over a calm pond, with a white lounge chair and a blue watercraft on the dock.

13. Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing

Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing
Grandin
10.0 out of 10, Exceptional, (23 reviews)
"The lodge was a wonderful place for the ten adults and two small children in our family to gather and spend a long weekend! We had everything we needed in the lodge. "
United States
Mitchell W.
The price is £527
includes taxes & fees
16 Sept - 17 Sept
Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Poplar Bluff Hotel Reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"Nice"
Carol 3-night trip
Posted 7 days ago
Motel 6 Poplar Bluff, MO

Find out more about Poplar Bluff

Poplar Bluff Holiday Homes information

Number of reviews
236
Accommodation
41 Holiday Homes
Lowest Price
£100
Highest Price
£527