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Check prices for these dates

Next weekend
29 Aug - 31 Aug
In two weeks
5 Sept - 7 Sept
In one month
19 Sept - 21 Sept
In two months
17 Oct - 19 Oct

Browse Select Pine Island Holiday Homes

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Exterior

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

10.0 out of 10, Exceptional, (8)
"House was exactly as described, very clean, quiet and cozy. Was perfect for my short stay visiting family. Would absolutely stay again. "
The price is £177
includes taxes & fees
22 Aug - 23 Aug
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
Fridge, microwave, oven, stovetop

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

2.0 star property
10.0 out of 10, Exceptional, (5)
"This is a very nice, clean, & well appointed property with wonderful access to Mayo & anything else you need to access in Rochester. Julie & her husband are also very responsive and attentive to making sure guests are extremely well taken care of - I’ve stayed at many vacation / VRBO homes & this one is a 10 of 10 !!!"
The price is £307
includes taxes & fees
3 Sept - 4 Sept
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Interior

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

9.0 out of 10, Wonderful, (15)
"Overall a good stay. The property was clean and mostly updated, but the home was very old. The foundation was slanted so much that items would roll off the table quickly and you could feel the slant when walking through the house."
The price is £208
includes taxes & fees
30 Aug - 31 Aug
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
1 mile to Mayo 2 step entry Brave Covered By Faith
Smart TV, DVD player, books, video library

1 mile to Mayo 2 step entry Brave Covered By Faith

2.0 star property
10.0 out of 10, Exceptional, (9)
"This was a PERFECT place to stay if you're going to the Mayo!Jessica is very easy to work with and incredibly responsive!"
The price is £199
includes taxes & fees
7 Sept - 8 Sept
1 mile to Mayo 2 step entry Brave Covered By Faith
The Cozy Hideaway - 5-Minute Drive to Mayo Clinic
Fridge, microwave, oven, stovetop

The Cozy Hideaway - 5-Minute Drive to Mayo Clinic

The price is £180
includes taxes & fees
22 Aug - 23 Aug
The Cozy Hideaway - 5-Minute Drive to Mayo Clinic
Close to Mayo & Shops, 1 step entry CoveredByFaith
Fridge, microwave, oven, stovetop

Close to Mayo & Shops, 1 step entry CoveredByFaith

9.8 out of 10, Exceptional, (11)
"Peaceful and relaxing, perfect vacation home. Excellent hosts!!!"
The price is £207
includes taxes & fees
24 Aug - 25 Aug
Close to Mayo & Shops, 1 step entry CoveredByFaith
Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets
Exterior

Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets

9.6 out of 10, Exceptional, (4)
"Very cute and well maintained. We would definitely stay again. "
Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Outdoor dining

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

9.6 out of 10, Exceptional, (18)
"Everything was excellent! Super happy"
The price is £249
includes taxes & fees
31 Aug - 1 Sept
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Elton Hills Park Quite 3-bedroom Spacious Home
Smart TV, books

Elton Hills Park Quite 3-bedroom Spacious Home

9.6 out of 10, Exceptional, (7)
"Clean little place with space for our family staying to visit our son at UMR. Would have liked there to be a large bowl for serving popcorn. "
The price is £264
includes taxes & fees
20 Sept - 21 Sept
Elton Hills Park Quite 3-bedroom Spacious Home
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Dining

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

The price is £160
includes taxes & fees
3 Sept - 4 Sept
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Terrace/patio

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

10.0 out of 10, Exceptional, (16)
"Very nice BnB! It's very cozy and welcoming..location is great! Will definitely be staying here again. Highly recommend this place!"
The price is £183
includes taxes & fees
21 Aug - 22 Aug
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Downtown rambler. 2 bed, 1 bath, office & fence.
Outdoor dining

Downtown rambler. 2 bed, 1 bath, office & fence.

8.0 out of 10, Very good, (5)
"This is a great house, we really like this part of town after staying here. property manager very responsive! We will stay here again!"
The price is £257
includes taxes & fees
1 Sept - 2 Sept
Downtown rambler. 2 bed, 1 bath, office & fence.
7 blks Mayo Gonda 8 blks St Marys 3 Bed Main Floor
Property grounds

7 blks Mayo Gonda 8 blks St Marys 3 Bed Main Floor

9.6 out of 10, Exceptional, (14)
" We were able to stay at the Harmony House a few blocks from the hospital. It worked well for us. Beds were very comfortable!"
The price is £210
includes taxes & fees
24 Aug - 25 Aug
7 blks Mayo Gonda 8 blks St Marys 3 Bed Main Floor
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
Property grounds

3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith

9.6 out of 10, Exceptional, (24)
"Good"
The price is £226
includes taxes & fees
1 Sept - 2 Sept
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
2 blks to St Marys 7 blks to Mayo Covered By Faith
Exterior

2 blks to St Marys 7 blks to Mayo Covered By Faith

9.2 out of 10, Wonderful, (18)
"Very clean, everything needed for a great stay."
The price is £249
includes taxes & fees
2 Sept - 3 Sept
2 blks to St Marys 7 blks to Mayo Covered By Faith
2 step entry 1 mile to Mayo CoveredByFaith Inspire
Fridge, microwave, oven, stovetop

2 step entry 1 mile to Mayo CoveredByFaith Inspire

The price is £202
includes taxes & fees
2 Sept - 3 Sept
2 step entry 1 mile to Mayo CoveredByFaith Inspire
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Interior

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

The price is £377
includes taxes & fees
22 Aug - 23 Aug
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pine Island Hotel Reviews

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent
"The property is south of city. Yet within minutes you can have food or shopping. From a simple security standpoint, anyone hanging around, or looking into vehicles, will be noticed."
Gerald 3-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S