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2 Oct - 4 Oct
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9 Oct - 11 Oct

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Our top choices for Penrose hotels

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

1. The West End

The West End
2.0 star property
Central West End, 2.6 mi from Penrose
8.6 out of 10, Excellent, (657 reviews)
"Very clean room and really good customer service"
United States
Sergio
The price is £82
includes taxes & fees
5 Oct - 6 Oct
The West End
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

2. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 4 mi from Penrose
9.4 out of 10, Exceptional, (1,000 reviews)
"This was an excellent location and the front desk staff made great recommendations for places to eat and things to do."
United States
Jennifer
The price is £123
includes taxes & fees
6 Oct - 7 Oct
Hampton Inn & Suites St. Louis at Forest Park
An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

3. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 3 mi from Penrose
8.6 out of 10, Excellent, (1,011 reviews)
"Lovely location and amazing room"
United States
Jacob
The price is £100
includes taxes & fees
5 Oct - 6 Oct
Aloft by Marriott St Louis Central West End
A rooftop restaurant with round tables, chairs, and a view of the city.

4. Moonrise Hotel

Moonrise Hotel
4.0 star property
3.6 mi from Penrose
9.0 out of 10, Wonderful, (2,031 reviews)
"Great location, clean rooms, and friendly staff. We will definitely stay again."
United States
Nicole
The price is £118
includes taxes & fees
4 Oct - 5 Oct
Moonrise Hotel
A hotel room with two beds, a chair, a desk, and a large window.

5. Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 4.9 mi from Penrose
7.4 out of 10, Good, (1,651 reviews)
"Comfortable bed and room. Friendly staff. Convenient location."
United States
Janice
The price is £72
includes taxes & fees
29 Oct - 30 Oct
Forest Park Hotel by MDR
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

6. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
2.7 mi from Penrose
8.8 out of 10, Excellent, (1,169 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is £105
includes taxes & fees
5 Oct - 6 Oct
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

7. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 2.7 mi from Penrose
8.8 out of 10, Excellent, (1,006 reviews)
"Room was clean and staff were friendly!"
United States
Lydia
The price is £129
includes taxes & fees
4 Oct - 5 Oct
Hotel Indigo St Louis - Central West End by IHG
The Clayton Plaza Hotel sign with a stone wall and plants in front.

8. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
5.7 mi from Penrose
8.8 out of 10, Excellent, (3,436 reviews)
"Great place to stay."
United States
Sivakumar
The price is £81
includes taxes & fees
11 Oct - 12 Oct
Clayton Plaza Hotel & Extended Stay
An indoor swimming pool with a glass ceiling, surrounded by potted plants and a tiled wall with a geometric pattern.

9. Casino Queen Hotel

Casino Queen Hotel
3.0 star property
5 mi from Penrose
7.8 out of 10, Good, (2,191 reviews)
"Nice stay"
United States
Shawna
The price is £65
includes taxes & fees
1 Oct - 2 Oct
Casino Queen Hotel
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

10. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 4.1 mi from Penrose
9.0 out of 10, Wonderful, (1,023 reviews)
"Great location"
United States
Kristy
The price is £87
includes taxes & fees
28 Oct - 29 Oct
Courtyard by Marriott St. Louis Downtown/Convention Center
A snack kiosk with a variety of packaged foods and beverages, a cash register, and a sign reading 'The Shop.'

11. Hilton Garden Inn St. Louis Airport

Hilton Garden Inn St. Louis Airport
3.0 star property
5.3 mi from Penrose
8.4 out of 10, Very good, (1,002 reviews)
"was just ok - could have been cleaner. front desk was nice but the room needed a deep clean."
United States
Antoinette
The price is £118
includes taxes & fees
8 Oct - 9 Oct
Hilton Garden Inn St. Louis Airport
A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

12. Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 4.4 mi from Penrose
8.2 out of 10, Very good, (411 reviews)
"Loved the breakfast."
United States
Daevontae
The price is £92
includes taxes & fees
29 Oct - 30 Oct
Comfort Inn & Suites Saint Louis Lafayette Square
An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

13. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 3.6 mi from Penrose
8.8 out of 10, Excellent, (2,215 reviews)
"The pool and food and rooms were nice"
United States
Michael
The price is £103
includes taxes & fees
5 Oct - 6 Oct
Pear Tree Inn St. Louis Near Union Station
A lobby with a reception desk, seating area, and a bicycle in the background.

14. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
5 mi from Penrose
9.4 out of 10, Exceptional, (1,017 reviews)
"Great place to stay"
United States
Robert
The price is £131
includes taxes & fees
11 Oct - 12 Oct
Drury Inn & Suites St. Louis Forest Park
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

15. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 3.4 mi from Penrose
8.6 out of 10, Excellent, (1,001 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is £137
includes taxes & fees
4 Oct - 5 Oct
Home2 Suites by Hilton St. Louis/Forest Park
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

16. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 2.7 mi from Penrose
9.2 out of 10, Wonderful, (1,014 reviews)
"Loved the location and everything about this place. Will definitely stay again"
United States
Tosha
The price is £182
includes taxes & fees
4 Oct - 5 Oct
The Royal Sonesta Chase Park Plaza St. Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

17. The Cheshire

The Cheshire
4.0 star property
4.8 mi from Penrose
8.8 out of 10, Excellent, (1,012 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is £133
includes taxes & fees
18 Oct - 19 Oct
The Cheshire
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

18. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 3.6 mi from Penrose
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice hotel, great staff. Directly across the street from Energizer/City Park. Parking is $25/night and well worth it."
United States
James
The price is £112
includes taxes & fees
26 Oct - 27 Oct
Fairfield Inn & Suites by Marriott St. Louis Downtown
A rooftop terrace with wicker furniture, offering a city view.

19. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 4.6 mi from Penrose
9.6 out of 10, Exceptional, (3,786 reviews)
"Excellent stay"
United States
Salvatore
The price is £119
includes taxes & fees
5 Oct - 6 Oct
Drury Plaza Hotel St. Louis at the Arch
An outdoor patio with a fire pit, seating, and a building in the background.

20. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
6.1 mi from Penrose
9.4 out of 10, Exceptional, (904 reviews)
"Clean comfortable room and mattress."
United States
Aaron
The price is £109
includes taxes & fees
11 Oct - 12 Oct
Courtyard by Marriott St. Louis Brentwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Penrose

Find the best Penrose areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A fountain in front of a red brick building with green roofs and white trim.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Penrose Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Breakfast was amazing. Great!"
Michael 10-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis Union Station

Frequently asked questions

What's it like in Penrose?
Travellers are sure to enjoy a stay in St. Louis's Penrose neighbourhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.
If I need to cancel my hotel reservation in Penrose, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Penrose.
What is there to do around this St. Louis neighbourhood?
Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.