What's it like in Penrose?

Travellers are sure to enjoy a stay in St. Louis's Penrose neighbourhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.

If I need to cancel my hotel reservation in Penrose, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Penrose.

What is there to do around this St. Louis neighbourhood?

Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.

The Best Hotels in Penrose, St. Louis - 2026 Updated Prices

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Our top choices for Penrose hotels

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

1. The West End

Central West End, 2.6 mi from Penrose

Adam

includes taxes & fees

16 Nov - 17 Nov

A snack kiosk with a variety of packaged foods and beverages, a cash register, and a sign reading 'The Shop.'

2. Hilton Garden Inn St. Louis Airport

5.3 mi from Penrose

Sorrell

includes taxes & fees

28 Nov - 29 Nov

A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

3. Tru By Hilton St. Louis Downtown

Downtown West, 3.9 mi from Penrose

Arthur

includes taxes & fees

11 Dec - 12 Dec

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

4. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4 mi from Penrose

Edmond

includes taxes & fees

22 Nov - 23 Nov

A rooftop restaurant with round tables, chairs, and a view of the city.

5. Moonrise Hotel

3.6 mi from Penrose

Rebecca

includes taxes & fees

16 Dec - 17 Dec

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

6. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 2.7 mi from Penrose

Sara

includes taxes & fees

22 Nov - 23 Nov

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

7. AC Hotel St. Louis Central West End

Central West End, 2.7 mi from Penrose

Janice

includes taxes & fees

19 Nov - 20 Nov

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

8. Hotel Indigo St Louis - Central West End by IHG

Central West End, 2.7 mi from Penrose

Gordon

includes taxes & fees

22 Nov - 23 Nov

A hotel room with two beds, a chair, a desk, and a large window.

9. Forest Park Hotel by MDR

The Hill, 4.9 mi from Penrose

Frantz

includes taxes & fees

16 Dec - 17 Dec

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

10. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

2.7 mi from Penrose

Stephanie

includes taxes & fees

22 Nov - 23 Nov

11. Drury Inn & Suites St. Louis Forest Park

5 mi from Penrose

Tammy

includes taxes & fees

22 Nov - 23 Nov

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

12. Comfort Inn & Suites Saint Louis Lafayette Square

The Gate, 4.4 mi from Penrose

Michelle

includes taxes & fees

6 Dec - 7 Dec

An outdoor patio area with seating, planters, and a grill.

13. Element by Marriott St. Louis Midtown

Midtown, 3 mi from Penrose

Julie

includes taxes & fees

22 Nov - 23 Nov

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

14. Pear Tree Inn St. Louis Near Union Station

Downtown West, 3.6 mi from Penrose

Samuwel

includes taxes & fees

22 Nov - 23 Nov

A hotel room with two beds, a desk, a chair, and a television.

15. Clayton Plaza Hotel & Extended Stay

5.7 mi from Penrose

Martha

includes taxes & fees

6 Dec - 7 Dec

An outdoor patio with a fire pit, seating, and a building in the background.

16. Courtyard by Marriott St. Louis Brentwood

6.1 mi from Penrose

Anna

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

17. DoubleTree by Hilton St. Louis Forest Park

Central West End, 3 mi from Penrose

Garland

includes taxes & fees

22 Nov - 23 Nov

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

18. The Cheshire

4.8 mi from Penrose

Matthew

includes taxes & fees

22 Nov - 23 Nov

An outdoor dining area with a glass table and chairs, a neon sign, and a city view.

19. Aloft by Marriott St Louis Central West End

Central West End, 3 mi from Penrose

Hulya

includes taxes & fees

16 Nov - 17 Nov

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

20. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 3.4 mi from Penrose

Ruth

includes taxes & fees

7 Dec - 8 Dec

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Compare popular hotels in Penrose

Property	Property class	Guest rating
Hampton Inn & Suites St. Louis at Forest Park	3.5 star property	9.4 Exceptional 1,000 reviews	View
Drury Plaza Hotel St. Louis Union Station	3.0 star property	9.4 Exceptional 1,625 reviews	View
Home2 Suites by Hilton St. Louis/Forest Park	3.0 star property	8.6 Excellent 1,001 reviews	View
Element by Marriott St. Louis Midtown	3.0 star property	8.8 Excellent 860 reviews	View
Drury Plaza Hotel St. Louis at the Arch	3.0 star property	9.6 Exceptional 3,841 reviews	View

Where to stay in Penrose

Find the best Penrose areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Penrose Hotel Reviews

Forest Park Hotel by MDR

10/10 Excellent

"Great"

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Staff was incredibly friendly in every interaction. Always asking if all was ok, if we’re having fun, did we do anything interesting that day. On weekends there’s a free Buffett dinner and bar drinks (5:30-7pm). Free daily breakfast was extensive. Very close to Gateway Arch, Busch Stadium and downtown parks. Convenient parking garage."

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Room had glitter in a large area near the window. So, I'm not sure how clean the floor was. It looked clean other than that. The bathroom and beds were clean. Staff was very friendly and helpful. Breakfast had a good selection and was good. Pool was like a sauna and enjoyable. It definitely needed cleaned. There was quite a bit of debris floating in it."

Search Hotels in Penrose, St. Louis

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Be picky

Check prices for these dates

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Property class

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Our top choices for Penrose hotels

1. The West End

2. Hilton Garden Inn St. Louis Airport

3. Tru By Hilton St. Louis Downtown

4. Hampton Inn & Suites St. Louis at Forest Park

5. Moonrise Hotel

6. The Royal Sonesta Chase Park Plaza St. Louis

7. AC Hotel St. Louis Central West End

8. Hotel Indigo St Louis - Central West End by IHG

9. Forest Park Hotel by MDR

10. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

11. Drury Inn & Suites St. Louis Forest Park

12. Comfort Inn & Suites Saint Louis Lafayette Square

13. Element by Marriott St. Louis Midtown

14. Pear Tree Inn St. Louis Near Union Station

15. Clayton Plaza Hotel & Extended Stay

16. Courtyard by Marriott St. Louis Brentwood

17. DoubleTree by Hilton St. Louis Forest Park

18. The Cheshire

19. Aloft by Marriott St Louis Central West End

20. Home2 Suites by Hilton St. Louis/Forest Park

Compare popular hotels in Penrose

Where to stay in Penrose

Downtown St. Louis

Clayton

St. Charles Historic District

Central West End

Creve Coeur

Top Penrose Hotel Reviews

Forest Park Hotel by MDR

Frequently asked questions