Panama Holidays from £899

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    Save up to £335 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Packages with flights are ATOL protected

Top Panama Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
per person
20 Sept - 27 Sept
found 1 day ago
Return direct flight included
London (LHR) to St. Louis (STL)
8.4/10 Very Good! (2,036 reviews)
Very nice place to stay and great location

Reviewed on 18 Aug 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
12 Oct - 17 Oct
found 24 hours ago
Return direct flight included
London (LHR) to St. Louis (STL)
9.2/10 Wonderful! (1,558 reviews)
Extremely soft cloud like bed and very friendly service. Hotel was clean and area is across from the Wildwood police precinct.

Reviewed on 14 Aug 2025

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
12 Oct - 17 Oct
found 24 hours ago
Return direct flight included
London (LHR) to St. Louis (STL)
8.2/10 Very Good! (760 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on 26 Jul 2025

The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
per person
12 Oct - 17 Oct
found 24 hours ago
Return direct flight included
London (LHR) to St. Louis (STL)
9.4/10 Exceptional! (364 reviews)
Every thing was fine but I accidentally booked a king room instead of two queens for move in day and rather than provide us with a cot, they made us rent a completely different room for $400. The guy working told me it happens every year so I felt a bit fleeced.

Reviewed on 17 Aug 2025

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed

4 out of 5
Central West End
per person
12 Oct - 17 Oct
found 24 hours ago
Return direct flight included
London (LHR) to St. Louis (STL)
9.2/10 Wonderful! (9 reviews)
Overall, we loved the apartment. It was cute, beds were very comfortable.

Reviewed on 8 May 2025

Panama Essential Information

Language
English
Currency
U.S dollars
Max Temp Winter
4ºC
Max Temp Summer
27ºC

Top hotels in Panama

Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield

2.5 out of 5
1405 W Hudson Dr, Litchfield, IL
Fully refundableReserve now, pay when you stay
The price is £72 per night from 31 Aug to 1 Sept
£72
31 Aug - 1 Sept
includes taxes & fees
8.2/10 Very Good! (1,003 reviews)
"Very nice people"

Reviewed on 17 Aug 2025

Baymont by Wyndham Litchfield
Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton

2 out of 5
1527 Herman Rd, Staunton, IL
Fully refundableReserve now, pay when you stay
The price is £58 per night from 25 Aug to 26 Aug
£58
25 Aug - 26 Aug
includes taxes & fees
8.4/10 Very Good! (736 reviews)
"It was a great hotel at a great room rate. Would definitely stay again. Comfy beds!"

Reviewed on 11 Aug 2025

Super 8 by Wyndham Staunton
Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG

2.5 out of 5
4 Thunderbird Circle, Litchfield, IL
Fully refundable
The price is £98 per night from 5 Sept to 6 Sept
£98
5 Sept - 6 Sept
includes taxes & fees
9.4/10 Exceptional! (546 reviews)
"Excellent"

Reviewed on 8 Aug 2025

Holiday Inn Express & Suites Litchfield West by IHG
See all 35 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Panama travel package cost?
From as low as £899. Yes, you read that correctly. Our Panama packages are a simple way to make your dollar go further. Combine your favourite hotels, flights and rental car and explore this lively destination.
If I'm not able to travel, can I cancel my Panama travel package?
It's good to know that you can cancel your Panama booking if your plans have changed. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. You may be able to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.
How do I get a cheap travel package to Panama?
One of the simplest ways to save money (and time) is to bundle your bookings with Expedia. Flights, rental cars, hotels and activities — we've got them all covered. Pick and choose the combination that suits your style and watch your savings pile up. We know a package deal is never a one-size-fits-all. That's why Expedia offers over 550 partner airlines and 1,000,000 hotels around the globe, which lets you customize your Panama holiday.
Does Expedia offer Book Now, Pay Later Panama holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has come up with a solution to help. Thanks to our partnership with online lender Klarna, it's easier than ever to book an incredible getaway without using up all your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's manageable monthly instalment plans. If paying just a little each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your trip over multiple transactions.
  • Low deposit holidays: Clicking on the "book now" button is much easier with this payment plan. Simply put down a small deposit on your escape and then start packing your suitcase.

What are the top hotels in Panama?
Get your escape off to a flying start by reserving a room at Baymont by Wyndham Litchfield. It's one of most sought-after properties in Panama. Another cosy option is Holiday Inn Express & Suites Litchfield West, an IHG Hotel.
How far in advance should I book my Panama holiday?
It's difficult to pick the best time for airfares, but we usually say the earlier, the better. Most international flights on Expedia become available up to 12 months in advance. If you can't book early, don't fret. Low prices occasionally appear just weeks before departure dates.
What does an Expedia Panama travel package include?
Flights, rental cars and hotels — we've got them covered. With Expedia, you can create your Panama package the way you like it. All you have to do is work out just what you need. Once you've made your booking, you can add extras like activities and tours. The more you bundle, the more you save!
What should I know before booking a Panama travel package?
Whether it's adventure or relaxation you're chasing, a Panama travel package lets you plan your escape your way. Plus, you'll get access to great discounts when you combine your hotel with your rental car and flights. The more you bundle, the bigger the savings!
Can I choose my airline with a Panama Expedia travel package?
With a travel package, you're the boss. Whether you want to fly to Panama in economy or business class, simply pick from the available airline options. Expedia has access to more than 550 airline partners worldwide.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.