Title: The Best Hotels Closest to Oklahoma Frontier Drugstore Museum in Guthrie - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Guthrie](https://expedia.co.uk/Guthrie-Holiday-Rentals.d7494.Travel-Guide-HolidayRentals)[Flights to Guthrie](https://expedia.co.uk/Cheap-Flights-To-Guthrie.d7494.Travel-Guide-Flights)[Oklahoma Frontier Drugstore Museum Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Oklahoma-Frontier-Drugstore-Museum.d928407067723894784.Car-Hire-Guide)[Oklahoma Frontier Drugstore Museum Holidays](https://expedia.co.uk/Oklahoma-Frontier-Drugstore-Museum-Guthrie.d928407067723894784.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=928407067723894784&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Feb - 13 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=928407067723894784&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=928407067723894784&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=928407067723894784&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Oklahoma Frontier Drugstore Museum hotels ![Front of property](https://images.trvl-media.com/lodging/24000000/23590000/23584500/23584426/329be6a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/24000000/23590000/23584500/23584426/aed6218d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/24000000/23590000/23584500/23584426/179e96fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/24000000/23590000/23584500/23584426/a6e9b734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dominion Gardens and Hotel [](https://www.expedia.co.uk/Guthrie-Hotels-Dominion-House.h23584426.Hotel-Information) 0.7 mi from Oklahoma Frontier Drugstore Museum 9.6/10 Exceptional (504 reviews) "staff is great! rooms are beyond spectacular@!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) leikasha £83 includes taxes & fees 20 Feb - 21 Feb [](https://www.expedia.co.uk/Guthrie-Hotels-Dominion-House.h23584426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/f3debf7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/137448b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | In-room safe, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/b0d56169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/763ab2db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Guthrie North Edmond by IHG [](https://www.expedia.co.uk/Guthrie-Hotels-Holiday-Inn-Express-Suites-Guthrie.h2858839.Hotel-Information) 1.6 mi from Oklahoma Frontier Drugstore Museum 8.4/10 Very good (1,000 reviews) "Nice stay for the price range! Good breakfast, friendly staff, clean room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chad £64 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Guthrie-Hotels-Holiday-Inn-Express-Suites-Guthrie.h2858839.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/a23aae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/07de5c99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/5210b1c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/a4b740d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Guthrie [](https://www.expedia.co.uk/Guthrie-Hotels-Hampton-Inn-Suites-Guthrie.h15703100.Hotel-Information) 1.8 mi from Oklahoma Frontier Drugstore Museum 8.4/10 Very good (998 reviews) "hotel is clean and very convenient access." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £69 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Guthrie-Hotels-Hampton-Inn-Suites-Guthrie.h15703100.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11570000/11567200/11567154/36be61b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Premium bedding, pillow-top beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11570000/11567200/11567154/559c6415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11570000/11567200/11567154/500fb81f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/12000000/11570000/11567200/11567154/3261b210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Guthrie [](https://www.expedia.co.uk/Guthrie-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Guthrie.h11567154.Hotel-Information) 1.8 mi from Oklahoma Frontier Drugstore Museum 8.2/10 Very good (978 reviews) "great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Landynne £64 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Guthrie-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Guthrie.h11567154.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/2697d94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/4d2eac88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/932451bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/973b15eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Territorial Inn - Guthrie [](https://www.expedia.co.uk/Guthrie-Hotels-Territorial-Inn-Guthrie.h12615.Hotel-Information) 1.8 mi from Oklahoma Frontier Drugstore Museum 8.2/10 Very good (802 reviews) "Clean rooms, staff was incredibly nice and breakfast was delicious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dwight [](https://www.expedia.co.uk/Guthrie-Hotels-Territorial-Inn-Guthrie.h12615.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/9a1236fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/284a90f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | In-room safe, iron/ironing board, cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/af398b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/58934206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Guthrie - Edmond North [](https://www.expedia.co.uk/Guthrie-Hotels-Sleep-Inn-Suites-Guthrie-Edmond-North.h440999.Hotel-Information) 1.8 mi from Oklahoma Frontier Drugstore Museum 7.8/10 Good (123 reviews) "Clean rooms, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £61 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/Guthrie-Hotels-Sleep-Inn-Suites-Guthrie-Edmond-North.h440999.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/ba7d0a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow | Private kitchen | Microwave](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/8534b4d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | Living area](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/w2502h1876x0y0-867df7b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | Living area](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/5a3e32b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Judge's Chambers [](https://www.expedia.co.uk/Guthrie-Hotels-The-Judges-Chambers.h112158721.Hotel-Information) 0.8 mi from Oklahoma Frontier Drugstore Museum 10/10 Exceptional (2 reviews) "We had a wonderful experience. The home is beautiful. We were there at Christmas time and it was beautifully decorated. Breakfast and coffee were delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelli £142 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/Guthrie-Hotels-The-Judges-Chambers.h112158721.Hotel-Information) ![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/a23af9a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/4d3a5abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/42a965ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/71505c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Interstate Motel Guthrie [](https://www.expedia.co.uk/Guthrie-Hotels-Interstate-Motel-Guthrie.h2499358.Hotel-Information) 1.5 mi from Oklahoma Frontier Drugstore Museum 6.0/10 (130 reviews) "The staff was so nice and the toom was comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Briana £54 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/Guthrie-Hotels-Interstate-Motel-Guthrie.h2499358.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27®ionId=928407067723894784&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Oklahoma Frontier Drugstore Museum | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Front of property](https://images.trvl-media.com/lodging/24000000/23590000/23584500/23584426/329be6a7.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Dominion Gardens and Hotel | 2.5 star property | 9.6Exceptional504 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/f3debf7c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Guthrie North Edmond by IHG | 2.5 star property | 8.4Very good1,000 reviews | View | | | | | | | ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/a23aae85.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Guthrie | 2.5 star property | 8.4Very good998 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/12000000/11570000/11567200/11567154/36be61b3.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Quinta Inn & Suites by Wyndham Guthrie | 3.0 star property | 8.2Very good978 reviews | View | | | | | | | ![Children’s play area – indoor](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/w866h647x0y0-8af0d428.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Territorial Inn - Guthrie | 2.5 star property | 8.2Very good802 reviews | View | | | | | | ## Top Oklahoma Frontier Drugstore Museum Hotel Reviews ![Hilton Garden Inn Oklahoma City North Quail Springs](https://images.trvl-media.com/lodging/3000000/2230000/2221400/2221373/2c5566c2_y.jpg) ### Hilton Garden Inn Oklahoma City North Quail Springs 10/10 Excellent "This hotel is a great , clean place to stay . And it is in a great location so it’s easy to grab the food of your choice. I would stay there again for sure. Very satisfied " [](https://expedia.co.uk/Oklahoma-City-Hotels-Hilton-Garden-Inn-Oklahoma-City-NorthQuail-Springs.h2221373.Hotel-Information) ![Stratford House Inns - Edmond](https://images.trvl-media.com/lodging/11000000/10540000/10539300/10539202/2b834415_y.jpg) ### Stratford House Inns - Edmond 10/10 Excellent " Check in was fast and easy. Friendly front desk attendant. Room was clean and shower had great water pressure." [](https://expedia.co.uk/Oklahoma-City-Hotels-Stratford-House-Inns-Edmond.h10539202.Hotel-Information) ![Garner Hotel Oklahoma City - Quail Springs by IHG](https://images.trvl-media.com/lodging/2000000/1710000/1709300/1709214/16a807cb_y.jpg) ### Garner Hotel Oklahoma City - Quail Springs by IHG 10/10 Excellent "The room was very comfortable and the staff kept the breakfast area very clean. The front staff was friendly " [](https://expedia.co.uk/Oklahoma-City-Hotels-Garner-Oklahoma-City-Quail-Springs.h1709214.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy](https://images.trvl-media.com/lodging/1000000/170000/165600/165560/7d2f000e_y.jpg) ### La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy 10/10 Excellent "Perfect" [](https://expedia.co.uk/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oklahoma-City-NW-Expwy.h165560.Hotel-Information) ![Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK](https://images.trvl-media.com/lodging/4000000/3630000/3626800/3626795/e37b306f_y.jpg) ### Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK 10/10 Excellent "The food was great! The staff was nice!" [](https://expedia.co.uk/Oklahoma-City-Hotels-Country-Inn-Suites-By-Radisson.h3626795.Hotel-Information) ![Holiday Inn Stillwater - University West by IHG](https://images.trvl-media.com/lodging/3000000/2210000/2206400/2206327/58558d62_y.jpg) ### Holiday Inn Stillwater - University West by IHG 10/10 Excellent "Staff was accommodating " [](https://expedia.co.uk/Stillwater-Hotels-Holiday-Inn-Stillwater-University-West.h2206327.Hotel-Information) ![Holiday Inn Express & Suites Oklahoma City North by IHG](https://images.trvl-media.com/lodging/6000000/5450000/5447800/5447724/47cae5a7_y.jpg) ### Holiday Inn Express & Suites Oklahoma City North by IHG 10/10 Excellent "Very clean, nicely laid out room. Love the chaise lounge. Staff friendly, upbeat." [](https://expedia.co.uk/Oklahoma-City-Hotels-Holiday-Inn-Express-Suites-Oklahoma-City-North.h5447724.Hotel-Information) ![Aloft Oklahoma City Quail Springs](https://images.trvl-media.com/lodging/71000000/70900000/70890200/70890140/4ef8fb0c_y.jpg) ### Aloft Oklahoma City Quail Springs 10/10 Excellent "Nice room, basic but very clean. Staff was friendly and helpful. I needed an early check in due to having a procedure and while I wasn’t able to get anyone to assist me beforehand when I reached out, they thankfully were able to accommodate me the day of. " [](https://expedia.co.uk/Oklahoma-City-Hotels-Aloft-Oklahoma-City-Quail-Springs.h70890140.Hotel-Information) ![avid hotel Oklahoma City - Quail Springs by IHG](https://images.trvl-media.com/lodging/25000000/24370000/24362600/24362586/4af615bc_y.jpg) ### avid hotel Oklahoma City - Quail Springs by IHG 10/10 Excellent "Excellent location " [](https://expedia.co.uk/Oklahoma-City-Hotels-Avid-Hotels-Oklahoma-City-Quail-Springs.h24362586.Hotel-Information) ## Hotels near other Oklahoma Frontier Drugstore Museum attractions ### Guthrie City Hall Guthrie City Hall is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Discover the area's festivals and temples. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407306482556928) ### Guthrie Historic District Learn about the local history of Guthrie when you spend time at Guthrie Historic District. Experience the area's festivals and live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407280928755712) ### Honor Park Honor Park is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Experience the area's festivals and live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928406884900487168) ### Pollard Theatre 3.9/5 (17 reviews) Enjoy a show at Pollard Theatre, a popular theatre in Guthrie. Experience the area's festivals and live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532647465) ### Guthrie Public Library Guthrie Public Library is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Experience the area's festivals and live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407343996403712) ### Guthrie Depot You can learn about the history of Guthrie with a visit to Guthrie Depot. Experience the area's festivals and live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950511771809034240) ### Jelsma Stadium Catch an event at Jelsma Stadium during your trip to Guthrie. Discover the area's festivals and temples. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407100934393856) ### Oklahoma Territorial Museum and Carnegie Library 4.1/5 (30 reviews) You can browse the exhibits at Oklahoma Territorial Museum and Carnegie Library, a museum with a storied past, during your travels to Guthrie. Experience the area's festivals and live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532647464) ## Frequently asked questions ### What's the area like around Oklahoma Frontier Drugstore Museum? ### What's the best place to stay near Oklahoma Frontier Drugstore Museum? ### How many hotels will I be able to find close to Oklahoma Frontier Drugstore Museum? ### If I need to cancel the hotel reservation for my stay near Oklahoma Frontier Drugstore Museum, will I receive a refund? ### What can I see and do near Oklahoma Frontier Drugstore Museum?