Title: The Best Hotels Closest to North Mississippi Medical Center in Tupelo - 2026 Updated Prices | Expedia.co.uk [Tupelo Travel Guide](https://expedia.co.uk/Tupelo.dx6058686)[Holiday Rentals in Tupelo](https://expedia.co.uk/Tupelo-Holiday-Rentals.d6058686.Travel-Guide-HolidayRentals)[Flights to Tupelo](https://expedia.co.uk/Cheap-Flights-To-Tupelo.d6058686.Travel-Guide-Flights)[North Mississippi Medical Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-North-Mississippi-Medical-Center.d6140198.Car-Hire-Guide)[North Mississippi Medical Center Holidays](https://expedia.co.uk/North-Mississippi-Medical-Center-Tupelo.d6140198.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [29 Mar - 30 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6140198&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [30 Mar - 31 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6140198&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6140198&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6140198&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for North Mississippi Medical Center hotels ![Restaurant](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/5e403676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/b4b35f75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/f1ef089d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Tupelo, a Wyndham Hotel [](https://www.expedia.co.uk/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) 1.3 mi from North Mississippi Medical Center 9.6/10 Exceptional (618 reviews) "Staff was so nice and gave an excellent place for dinner, called The Forklift. Highly recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £123 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/c2002907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/8d0dca5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/a0b90111.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hotel & Suites Tupelo North by IHG [](https://www.expedia.co.uk/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) 1.9 mi from North Mississippi Medical Center 9.2/10 Wonderful (1,005 reviews) "Room was great very nice hotel, restaurant fantastic!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hailie £102 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/99907b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/5607cbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/38bad4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/88bc3b11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) 1.4 mi from North Mississippi Medical Center 8.2/10 Very good (1,002 reviews) "Easy parking, tons of restaurants within walkable distance. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christal £90 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/71a98cb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/a0411a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/aaf1c148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/5808ace1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Tupelo North [](https://www.expedia.co.uk/Tupelo-Hotels-SureStay-Hotel-By-Best-Western-Tupelo-North.h3874642.Hotel-Information) 1.7 mi from North Mississippi Medical Center 7.4/10 Good (245 reviews) "Tub to work. Hold water. Stopper was messed up. Have free gifts baggies for the customers " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Belinda £48 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-SureStay-Hotel-By-Best-Western-Tupelo-North.h3874642.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/c1bb111f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/766133a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/05962f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/15b1a386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites Tupelo, MS - North [](https://www.expedia.co.uk/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) 1.9 mi from North Mississippi Medical Center 7.4/10 Good (556 reviews) "Clean and very reasonable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine £46 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) ![Individually furnished, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/db5ef9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/6f08dfa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/34eaa937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/7d82dd7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Tupelo, MS - Downtown [](https://www.expedia.co.uk/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) 1.8 mi from North Mississippi Medical Center 6.8/10 (286 reviews) "it is conveniently close to the interstate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet £48 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/4cab39f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/9a140bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/01226df3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/0a336343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottish Inns [](https://www.expedia.co.uk/Tupelo-Hotels-Scottish-Inns.h903414.Hotel-Information) 1.3 mi from North Mississippi Medical Center 5.6/10 (94 reviews) "Awesome beds and quite " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £49 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Scottish-Inns.h903414.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/15eb656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/5ba41635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/6030527c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/6902bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Tupelo by IHG [](https://www.expedia.co.uk/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) 2.6 mi from North Mississippi Medical Center 9.4/10 Exceptional (1,001 reviews) "I always stay here when visiting Tupelo, and have never had a bad experience. Staff is friendly, rooms are clean and breakfast is delicious! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martha £97 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/c0a90d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/4b9db4c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast ](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/ee19c8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/bdb9d441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Tupelo, Ms [](https://www.expedia.co.uk/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) 2.6 mi from North Mississippi Medical Center 9.4/10 Exceptional (399 reviews) "My entire stay was wonderful.. I will most definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LaJaysha £91 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/272130c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/33b16390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/70dd7cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) 2.3 mi from North Mississippi Medical Center 8.6/10 Excellent (1,002 reviews) "Family friendly and Pet friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandro £83 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/3e72a44d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/c42a976c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/06eb4d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) 2.2 mi from North Mississippi Medical Center 8.4/10 Very good (1,008 reviews) "Great Stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £55 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/50d63d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/ceef32e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/27a1c79d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/46ee23a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) 2.7 mi from North Mississippi Medical Center 9.2/10 Wonderful (693 reviews) "Hotel was very nice and clean. The breakfast was also better than most hotels. Enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) denise £85 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/974b178f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/adc59a10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/e152cdd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/de2d5184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Tupelo Central [](https://www.expedia.co.uk/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) 2.2 mi from North Mississippi Medical Center 8.2/10 Very good (1,000 reviews) "The hotel was close to the hospital. The staff was very accommodating and the rooms were very clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen £66 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/93da9926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/dcc3bdc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/14fa7bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/6e4e6119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Courtyard-By-Marriott-Tupelo.h42285.Hotel-Information) 2.4 mi from North Mississippi Medical Center 8.4/10 Very good (314 reviews) "Good experience, will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lamont £99 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Courtyard-By-Marriott-Tupelo.h42285.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/a4930614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/2660a6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/e630b24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/786994c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Tupelo Central [](https://www.expedia.co.uk/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) 2.5 mi from North Mississippi Medical Center 7.8/10 Good (549 reviews) "Great hot breakfasts with homemade eggs and potatoes " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £55 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) ![Presidential Studio Suite, 1 King Bed, Non Smoking, Pool View | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/db91ffba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 11:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/97b5a707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking, Pool View | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/w2999h2000x0y0-850de2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/f84f5240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) 2.6 mi from North Mississippi Medical Center 7.6/10 Good (1,003 reviews) "The rooms where clean and the staff was nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandi £55 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Standard Room, 2 Queen Beds | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/b694ac45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/2d49d2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/0a918b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/329e3e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Days-Inn-By-Wyndham-Tupelo.h23221.Hotel-Information) 2.3 mi from North Mississippi Medical Center 6.8/10 (369 reviews) "Great place to say everyone was friendly and very close to all the sites" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Piper £51 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Days-Inn-By-Wyndham-Tupelo.h23221.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/f27f3041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/53543e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/e355fdf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Tupelo Inn & Suites [](https://www.expedia.co.uk/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) 3.9 mi from North Mississippi Medical Center 8.8/10 Excellent (1,004 reviews) "I stay here quite often and I highly recommend. Great location! Walking distance to great food as well." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) terence £81 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/6524fbce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/c62b8d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/0cf1b94f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/cc405a28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Tupelo Barnes Crossing [](https://www.expedia.co.uk/Tupelo-Hotels-Econolodge-Tupelo.h539490.Hotel-Information) 4.3 mi from North Mississippi Medical Center 6.8/10 (395 reviews) "Clean rooms , friendly staff , quick check inn " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marshawn £51 includes taxes & fees 30 Apr - 1 May [](https://www.expedia.co.uk/Tupelo-Hotels-Econolodge-Tupelo.h539490.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/4908d4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/c64252d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/ebb3eb99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/46ec20f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Tupelo [](https://www.expedia.co.uk/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) 3.9 mi from North Mississippi Medical Center 8.4/10 Very good (1,007 reviews) "Room was clean staff was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald £81 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14®ionId=6140198&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to North Mississippi Medical Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Restaurant](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Tupelo, a Wyndham Hotel | 3.0 star property | 9.6Exceptional618 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Hotel & Suites Tupelo North by IHG | 3.0 star property | 9.2Wonderful1,005 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/99907b0c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hilton Garden Inn Tupelo | 3.0 star property | 8.2Very good1,002 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/71a98cb6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)SureStay Hotel by Best Western Tupelo North | 2.5 star property | 7.4Good245 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/c1bb111f.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Studio 6 Suites Tupelo, MS - North | 2.5 star property | 7.4Good556 reviews | View | | | | | | ## Top North Mississippi Medical Center Hotel Reviews ![Spark by Hilton Tupelo](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/4908d4cd_y.jpg) ### Spark by Hilton Tupelo 10/10 Excellent "Great hotel, close to interstate, very clean and easy!" [](https://expedia.co.uk/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) ![Quality Inn Tupelo Central](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/a4930614_y.jpg) ### Quality Inn Tupelo Central 8/10 Good "Breakfast good. Area okay. Some damage in the room." [](https://expedia.co.uk/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) ![Motel 6 Tupelo, MS - Downtown](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/db5ef9d5_y.jpg) ### Motel 6 Tupelo, MS - Downtown 8/10 Good "Great" [](https://expedia.co.uk/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) ![Red Roof Inn Tupelo](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5_y.jpg) ### Red Roof Inn Tupelo 10/10 Excellent "I enjoy red roof Inn because you get friendly, helpful staff and the rooms are always clean and spacious. It has a breakfast that starts early and their pet friendly. And just basically no hassles and amazing affordability in the location could not have been better." [](https://expedia.co.uk/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tupelo](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b_y.jpg) ### La Quinta Inn & Suites by Wyndham Tupelo 10/10 Excellent "Great " [](https://expedia.co.uk/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Holiday Inn Express Hotel & Suites Tupelo by IHG](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/15eb656f_y.jpg) ### Holiday Inn Express Hotel & Suites Tupelo by IHG 6/10 Okay "The breakfast was great. Parking was accessible and the staff was friendly. The room was very dusty over the headboards of the beds and the television. We stayed on the second floor and the ceiling was extremely creaky. Luckily we had some sound machines to diminish the noise. Other then that, the hotel was great. " [](https://expedia.co.uk/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Holiday Inn Hotel & Suites Tupelo North by IHG](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa_y.jpg) ### Holiday Inn Hotel & Suites Tupelo North by IHG 8/10 Good "Room was spacious but we found a roach under sofa bed " [](https://expedia.co.uk/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Baymont by Wyndham Tupelo](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/db91ffba_y.jpg) ### Baymont by Wyndham Tupelo 4/10 Poor "Our room was sweltering hot. When I told the front desk clerk that it was so uncomfortable she just said “oh, I’m sorry.” Lol Breakfast was far less options that other hotels of this caliber. Bath tub was less than clean. Bathroom floors in the corners looked like that hadn’t been cleaned in a decade. Solid disappointment with this hotel." [](https://expedia.co.uk/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Hotel Tupelo, a Wyndham Hotel](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e_y.jpg) ### Hotel Tupelo, a Wyndham Hotel 10/10 Excellent "Beautiful hotel! Gorgeous, artsy decor, huge room, warm and friendly staff. Great vibe. My only complaint at all was that there was no "grab and go" breakfast for us to grab while we were getting ready to go. Young lady at restaurant counter said they didn't have staff that morning to make the biscuits, which I thought was really strange for a Saturday. But she was so lovely and nice that I couldn't be upset about it. Anyway, I would definitely stay at Hotel Tupelo again!" [](https://expedia.co.uk/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) ## Hotels near other North Mississippi Medical Center attractions ### Tupelo Buffalo Park 4.0/5 (71 reviews) Why not see the exotic and native animals who live at Tupelo Buffalo Park during your trip to Tupelo? Visit the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655102) ### Tupelo National Battlefield 3.8/5 (66 reviews) Explore the great outdoors at Tupelo National Battlefield, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092633) ### BancorpSouth Arena 4.3/5 (151 reviews) Catch an event at BancorpSouth Arena during your trip to Tupelo. Visit the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092629) ### Rob Leake City Park Tennis Center Catch an event at Rob Leake City Park Tennis Center during your trip to Tupelo. Visit the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624716639272960) ### Ballard Park 4.2/5 (110 reviews) Explore the great outdoors at Ballard Park, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655097) ### Elvis Presley Center 4.2/5 (168 reviews) You can spend time exploring the galleries in Elvis Presley Center during your trip to Tupelo. Visit the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655101) ### Oren Dunn City Museum 3.7/5 (19 reviews) You can spend time browsing the exhibits at Oren Dunn City Museum during your travels in Tupelo. Visit the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655096) ### Elvis Presley Lake and Campground 4.1/5 (51 reviews) Explore the great outdoors at Elvis Presley Lake and Campground, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655103) ## Frequently asked questions ### What's the area like around North Mississippi Medical Center? ### What's the best place to stay close to North Mississippi Medical Center? ### How many hotels should I expect to find near North Mississippi Medical Center? ### If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund? ### What can I see and do near North Mississippi Medical Center?