Either it's because of the amount of competition nearby, or maybe because the trains run in front of the hotel, but the fact of the matter is, I was shocked at how new and clean and overall excellent this hotel is for the price. The staff at the front desk both at night and in the morning were incredibly accommodating and helpful. The room is huge by European standards, and immaculately clean. The bathroom is large is well, and even the shower is big enough to turn around in, which is uncommon in French hotels in my experience. The room had a kettle with instant coffee and tea, and the cable for the TV had some English channels, such as BBC world. All of the fixtures in the halls and in the rooms looked new, and to be perfectly honest, in Canada, a hotel this nice would have cost twice as much, maybe more.
The tracks for the TGV and the intercity trains do run directly in front of the hotel, but I did not find that they disturbed my sleep. I don't know if the trains run 24 hours a day, but it wasn't a problem with the windows closed.
Hotel Kyriad is located less than a block away from Gare de Nice. Lots of nice restaurants in the area.
There was plenty of linen in the washroom, a big wardrobe for clothes in the sleeping area with a safe inside if you need to store your valuables, and fast reliable Wi-Fi. I have spent almost a week in France now on this trip, and so far Hotel Kyriad has been my best hotel experience yet.