Title: Museum of Science and Technology in Downtown Syracuse | Expedia.co.uk [Museum of Science and Technology Hotels](https://expedia.co.uk/Museum-Of-Science-And-Technology-Hotels.0-l6066115-0.Travel-Guide-Filter-Hotels)[Museum of Science and Technology Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Museum-Of-Science-And-Technology.d6066115.Car-Hire-Guide)[Downtown Syracuse Holidays](https://expedia.co.uk/Downtown-Syracuse.d6056151.Holidays-City-Breaks) # Museum of Science and Technology ![Museum of Science and Technology](https://images.trvl-media.com/place/6066115/8d7f046d-e03a-45aa-9f55-5446be962cfe.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Museum of Science and Technology](https://images.trvl-media.com/place/6066115/9d8db6a5-964b-41b1-9519-cd35b0f7e509.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Museum of Science and Technology](https://images.trvl-media.com/place/6066115/1195655d-4bf8-41bb-b065-5cf1d0802122.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Museum of Science and Technology](https://images.trvl-media.com/place/6066115/982b9623-cd0c-4f72-a9d9-6e8ad25d7574.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Museum of Science and Technology](https://images.trvl-media.com/place/6066115/c558df89-f629-408e-8713-7b13e854060f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Museum of Science and Technology Activities --- --- #### Kids and adults will love this Syracuse museum, featuring an IMAX theatre, interactive exhibits and possibly the world’s largest collection of toothpick sculptures. It’s not uncommon to see adults having even more fun than kids at Syracuse’s Museum of Science and Technology, often referred to as MOST. Dinosaur bones are only the beginning, as the museum offers countless opportunities to learn and play. Visit this huge castle-like building that dominates Armory Square. It is the perfect family destination on one of Syracuse’s frosty winter days. Shoot up into the sky in the realistic flight simulator that will make you feel like a flying ace or shoot hoops in the virtual reality basketball exhibit. If it is open, don’t miss the Rothschild Apothecary Shop, a recreation of a turn-of-the-century pharmacy staffed by friendly and knowledgeable volunteers. Try to guess which now-illegal drugs were prescribed for what maladies a hundred years ago. Walk through the enormous replica of a beating heart. Be awed by the Guinness World Record-holding toothpick display, where a local Syracuse man has built models of the world’s tallest buildings out of nothing but toothpicks and glue, all at 1/164 size. Watch a movie at a domed IMAX theater, where films displaying the beauty of nature are projected. Study the stars during one of the planetarium shows. Help your kids burn off some energy and learn about basic physics in the museum’s enormous Science Playhouse, which features a climbing wall and giant foam pieces for kids to use as building blocks. Relax by bringing picnic food and having a snack as your kids teach you about all they’ve learned. The MOST is located in Armory Square in central Syracuse. Catch the shuttle bus from Syracuse University’s campus or drive to the square in 20 minutes from the Syracuse Airport. Free parking is available in an adjacent lot and metered street parking is close by. The museum is open from Wednesday to Sunday from mid-morning to late afternoon and is open late on the second Thursday of every month. There is an admission fee, with extra charges for the planetarium and the IMAX theater. ### Popular places to visit ![Armory Square](https://images.trvl-media.com/place/6163997/e86714a7-2c4f-4613-885b-ec3748e247f2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Armory Square 4/5(1 review) Home to Syracuse’s highest concentration of bars and restaurants, this lively city square is the perfect place for a night out in Central New York. [](https://expedia.co.uk/Armory-Square-Downtown-Syracuse.d6163997.Attraction) ![Landmark Theatre](https://images.trvl-media.com/place/6127035/78dc55ff-4986-4d3e-8ec9-6d6f5a1e0d2f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Landmark Theatre See Broadway musicals, comedy or rock shows at this beautiful and supposedly haunted 1920s venue just off Syracuse’s Armory Square. [](https://expedia.co.uk/Landmark-Theatre-Downtown-Syracuse.d6127035.Attraction) ![Clinton Square](https://images.trvl-media.com/place/6066123/fdb9e53e-f458-4c14-902f-a97b1ad9ffbd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Clinton Square Nestled in the heart of Syracuse’s downtown, this historic plaza is known for its civic mindedness, hosting countless festivals and a community ice skating rink. [](https://expedia.co.uk/Clinton-Square-Downtown-Syracuse.d6066123.Attraction) ![Everson Museum of Art](https://images.trvl-media.com/place/6066113/c0ae83a4-e1da-46c5-8754-0153f3b26089.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Everson Museum of Art 4/5(1 review) Brutalist architecture, American art and one of the world’s finest ceramics collections come together at this small but mighty museum in Syracuse’s downtown. [](https://expedia.co.uk/Everson-Museum-Of-Art-Downtown-Syracuse.d6066113.Attraction) #### La Casita Cultural Center Enjoy an outing to La Casita Cultural Center during your stay in Syracuse. [](https://expedia.co.uk/La-Casita-Cultural-Center-Westside.d1001621828711858176.Attraction) #### Salt City Market You can find the perfect gifts to bring home at Salt City Market during your visit to Syracuse. While you're here, you can savour the top-notch restaurants. [](https://expedia.co.uk/Salt-City-Market-Downtown-Syracuse.d940906553513840640.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Museum of Science and Technology [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6066115&startDate=2026-03-28&endDate=2026-03-29)[28 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6066115&startDate=2026-03-28&endDate=2026-03-29) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6066115&startDate=2026-03-29&endDate=2026-03-30)[29 Mar - 30 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6066115&startDate=2026-03-29&endDate=2026-03-30) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6066115&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6066115&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) ![The Parkview Hotel](https://images.trvl-media.com/lodging/2000000/1200000/1191300/1191281/2779d7be_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Parkview Hotel 713 E Genesee St Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-The-Parkview-Hotel.h1191281.Hotel-Information) ![Marriott Syracuse Downtown](https://images.trvl-media.com/lodging/1000000/30000/22500/22422/0093350a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Syracuse Downtown 100 East Onondaga Street Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Marriott-Syracuse-Downtown.h22422.Hotel-Information) ![Best Western Syracuse Downtown Hotel and Suites](https://images.trvl-media.com/lodging/1000000/610000/607200/607148/eb462978_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Syracuse Downtown Hotel and Suites 416 S Clinton St Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Jefferson-Clinton-Suites.h607148.Hotel-Information) ![Embassy Suites by Hilton Syracuse Destiny USA](https://images.trvl-media.com/lodging/20000000/19190000/19187200/19187159/d2efdae0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Embassy Suites by Hilton Syracuse Destiny USA 311-371 Hiawatha Blvd. Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Embassy-Suites-By-Hilton-Syracuse-Destiny-USA.h19187159.Hotel-Information) ![Super 8 by Wyndham Liverpool/Syracuse North Airport](https://images.trvl-media.com/lodging/1000000/70000/66700/66620/e7e09b33_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Super 8 by Wyndham Liverpool/Syracuse North Airport 421 7th North Street Liverpool NY [](https://expedia.co.uk/Syracuse-Hotels-Super-8-By-Wyndham-LiverpoolSyracuse-North-Airport.h66620.Hotel-Information) ![Clarion Pointe Downtown](https://images.trvl-media.com/lodging/1000000/10000/600/600/fd1bdf4e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clarion Pointe Downtown 454 James Street Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Quality-Inn-Suites-Downtown.h600.Hotel-Information) ![Courtyard Syracuse Downtown At Armory Square](https://images.trvl-media.com/lodging/6000000/5960000/5952900/5952824/08986023_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard Syracuse Downtown At Armory Square 300 West Fayette Street Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Courtyard-Syracuse-Downtown-At-Armory-Square.h5952824.Hotel-Information) ![Aloft Syracuse Inner Harbor](https://images.trvl-media.com/lodging/16000000/15140000/15136700/15136686/4714dab7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aloft Syracuse Inner Harbor 310 West Kirkpatrick Street Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Aloft-Syracuse-Inner-Harbor.h15136686.Hotel-Information) ![Residence Inn by Marriott Syracuse Downtown at Armory Square](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963284/435bb8dd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residence Inn by Marriott Syracuse Downtown at Armory Square 300 West Fayette Street Syracuse NY [](https://expedia.co.uk/Syracuse-Hotels-Residence-Inn-By-Marriott-Syracuse-Downtown-At-Armory-Square.h5963284.Hotel-Information) [See all 1,023 properties in Museum of Science and Technology](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6066115) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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