A baseball stadium filled with spectators during a game.

Search Business Hotels in Mississippi Gulf Coast

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Mississippi Gulf Coast Business Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Mississippi Gulf Coast business-friendly hotels

A pool area with blue umbrellas, lounge chairs, and palm trees.
A spa room with reclining chairs, large windows, and a view of a pool area.
A restaurant interior with round tables, green upholstered seating, and hanging pendant lights.
A bar area with a central bar counter, multiple screens displaying sports, and yellow bar stools.

1. Beau Rivage

Beau Rivage
Downtown Biloxi
United States
Lazell
£127
includes taxes & fees
25 Oct - 26 Oct
Beau Rivage
A modern spa interior with a prominent sign for 'pure THE PALACE SPA'.
A lobby with a large illuminated letter 'P' on the wall, a reception desk, a staircase, and a patterned carpet.
A large, two-story building with a stone facade, a central entrance with steps, and a symmetrical design.
A modern hotel with a large pool area, outdoor seating, and a covered pavilion.

2. Palace Casino Resort

Palace Casino Resort
Biloxi
United States
andrew
£62
includes taxes & fees
1 Nov - 2 Nov
Palace Casino Resort
A resort pool area with lounge chairs, palm trees, and a bar.
A hotel room with a large bed, a desk with a tray of amenities, a TV, and a balcony with a view of the sea.
A casino with multiple gaming tables and slot machines.
A hotel room with two beds, a desk with a TV, a seating area, and a view of the sea.

3. Golden Nugget Biloxi

Golden Nugget Biloxi
Downtown Biloxi
United States
Raymond
£50
includes taxes & fees
26 Oct - 27 Oct
Golden Nugget Biloxi
A miniature golf course with a volcano-themed obstacle, palm trees, and a parking structure in the background.
A restaurant with black and white patterned flooring, white and black striped chairs, and a large tree with hanging lights.
A multi-story hotel with a distinctive curved facade, named "Scarlet Pearl," featuring a modern architectural design and surrounded by palm trees.
A modern bar area with a variety of seating options, including tables and chairs, and a large illuminated display wall.

4. Scarlet Pearl Casino Resort

Scarlet Pearl Casino Resort
D'Iberville
United States
Paul
£63
includes taxes & fees
28 Oct - 29 Oct
Scarlet Pearl Casino Resort
A bathroom with a bathtub, a window with a view of the sea, and a beige tiled wall.
A modern lobby with a curved reception desk, large hanging lamps, and a neon sign indicating the address.
A lobby with a central staircase, a chandelier, and a reception desk.
A high-rise hotel with a prominent 'IP' sign, surrounded by palm trees and a busy street with light trails.

5. IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi
Biloxi
United States
Kimberly
£71
includes taxes & fees
1 Nov - 2 Nov
IP Casino Resort Spa - Biloxi
A spacious lobby with a bar area, seating arrangements, and large windows offering views.
A modern restaurant with wooden accents, a bar area, and a gift shop.
A pool area with multiple water slides and a rock formation.
A balcony with wicker furniture overlooking a marina with boats and a distant shoreline.

6. Margaritaville Resort Biloxi

Margaritaville Resort Biloxi
Downtown Biloxi
United States
Michaela
£84
includes taxes & fees
25 Oct - 26 Oct
Margaritaville Resort Biloxi
A reception area with a glass door entrance, a wall-mounted digital display, and a counter with a blue backlit panel.
A hotel room with striped armchairs, a small table, a TV mounted on a wooden cabinet, and a refrigerator in the background.
A modern hotel lobby with a reception desk, seating areas, and a large TV screen.
A gym with dumbbells, a bench press, and a large mirror.

7. Best Western Plus D'Iberville

Best Western Plus D'Iberville
D'Iberville
United States
Kristina
£57
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus D'Iberville
A pool area with lounge chairs and towels, a fence, palm trees, and a lighthouse in the background.
A dining table set with multiple wine glasses, a bowl, and cutlery, with a cityscape photo on the wall behind.
A hotel reception desk with a marble wall, a logo, and a door in the background.
Two white chairs, a glass table, and a martini glass with a drink.

8. The Markham Hotel

The Markham Hotel
Gulfport
United States
Ashleigh
£88
includes taxes & fees
18 Oct - 19 Oct
The Markham Hotel
A classic white building with columns and black shutters, a vintage car parked in front, and well-maintained greenery.
A hotel reception area with a wooden reception desk, a large 'H' sign, and a bar in the background.
A modern interior with a white sofa, a decorative vase, and a large window with blinds.
A grand piano in a spacious room with patterned carpet, elegant chairs, and hanging light fixtures.

9. White House Hotel

White House Hotel
Biloxi
Australia
Jodie
£91
includes taxes & fees
21 Oct - 22 Oct
White House Hotel
A pool with clear blue water, palm trees, and a beach view.
A dining area with tables and chairs, large windows with a view of the beach and traffic lights, and pendant lights.
A beach with clear shallow waters leading to a sandy shore.
A hotel reception area with a view of the beach, a desk with a computer, and a sign for HP Holiday Inn Express.

10. Holiday Inn Express Gulfport Beach by IHG

Holiday Inn Express Gulfport Beach by IHG
Gulfport
United States
MIRANDA
£100
includes taxes & fees
12 Oct - 13 Oct
Holiday Inn Express Gulfport Beach by IHG
View all properties

Top Mississippi Gulf Coast Hotel Reviews

Margaritaville Resort Biloxi

Margaritaville Resort Biloxi

10/10 Excellent
"Everyone was so nice and helpful! The head security guard Big Mike, was amazing!! I knew I could leave my antique car in the parking garage and he would watch over it! He was so friendly and personable. He made sure to always speak to me."
Elizabeth 6-night trip
Posted less than an hour ago
Margaritaville Resort Biloxi
Golden Nugget Biloxi

Golden Nugget Biloxi

10/10 Excellent
"Great stay. Clean rooms. Mattress a little hard but ok. Shower head was pretty terrible though. Other than that really pleased. Lilly’s restaurant was fantastic. Bubba Gump was solid. Saltgrass right across the street was great. They need more nightly entertainment which would be a nice addition."
Steven 5-night trip
Posted 1 hour ago
Golden Nugget Biloxi
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

10/10 Excellent
"The room was spacious, clean, and beautifully decorated…highly recommend IP for accommodations and activities on site"
Misty 1-night trip
Posted 2 hours ago
IP Casino Resort Spa - Biloxi
Motel 6 Biloxi, MS - Beach

Motel 6 Biloxi, MS - Beach

8/10 Good
"As far as cleanliness the house, the house is clean the room very well kept The view of the beach was wonderful. We had three wonderful days of good weather. Great weather helpful staff. What bothered me the most was there was no coffee pot in the rooms so that you could make your own cup of coffee and they stop serving it after breakfast because they said management had told them not to make no more after 10 o’clock in the morning and not to make it to 6 AM. They didn’t even have instant coffee, where you can heat the water in the microwave. If you don’t wanna put coffee.pots in the rooms at least make coffee at least a half a pot every two hours would not kill management. It’s all about the money. That’s all it is anymore. Get the comfortableness of your travelers where they may want to rest and just have a cup of coffee at night during watching TV that’s my favorite habit. That’s why I travel I like being in a different place tasting different coffees. I was very disappointed this time I stayed in this hotel, same hotel in Biloxi and they’ve always had a coffee pot. They used put two little pods of coffee in the room. If you wanted more, you could go down to the front desk and they would give you one ."
Debra 3-night trip
Posted 2 hours ago
Motel 6 Biloxi, MS - Beach
Hard Rock Hotel & Casino Biloxi

Hard Rock Hotel & Casino Biloxi

10/10 Excellent
"We needed handicap accommodation and they did a great job room 721 awesome"
Susan 3-night trip
Posted 5 hours ago
Hard Rock Hotel & Casino Biloxi
Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination

Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent
"Was great"
SHANNON 4-night trip
Posted 11 hours ago
Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination
Beau Rivage

Beau Rivage

8/10 Good
"Property was nice but the upgrade was not that impressive. Made the mistake and got room service and was very expensive and food was terrible. $80 for 2 sandwiches, lesson learned"
Angel 2-night trip
Posted 16 hours ago
Beau Rivage
South Beach Biloxi Hotel & Suites

South Beach Biloxi Hotel & Suites

10/10 Excellent
"Very very very friendly staff I love everything about it I will be back"
Terrilyn 3-night trip
Posted 11 days ago
South Beach Biloxi Hotel & Suites

Frequently asked questions

How much do business hotels in Mississippi Gulf Coast cost?
Prices for business hotels in Mississippi Gulf Coast range between £50 and £127 per night. No matter your budget, Expedia can help you locate the right place to complete the job. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Mississippi Gulf Coast?
Choose from 109 business hotels in Mississippi Gulf Coast. When your job takes you on the road, Expedia will help you secure the ideal space with the amenities you're looking for.
Why book your business hotel in Mississippi Gulf Coast with Expedia?
At Expedia, our job is to help you land an amazing stay at the right price. From upmarket, corporate-friendly getaways to affordable motels filled with all the amenities you need, you'll have your next work trip booked in just a few clicks.
How can I find cheap business hotels in Mississippi Gulf Coast?
When work takes you to Mississippi Gulf Coast, our "business friendly" filter will help you find a suitable hotel. From dependable WiFi to meeting rooms and workspaces, they come with the amenities you need for a comfortable and productive stay. Another tip? Refine your search by your preferred star rating and budget to see the most affordable stays.

Explore a world of travel with Expedia