Title: Mission San Luis Obispo de Tolosa in Downtown San Luis Obispo | Expedia.co.uk [Mission San Luis Obispo de Tolosa Hotels](https://expedia.co.uk/Mission-San-Luis-Obispo-De-Tolosa-Hotels.0-l6089181-0.Travel-Guide-Filter-Hotels)[Mission San Luis Obispo de Tolosa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-San-Luis-Obispo-De-Tolosa.d6089181.Car-Hire-Guide)[Downtown San Luis Obispo Holidays](https://expedia.co.uk/Downtown-San-Luis-Obispo.d553248635976479118.Holidays-City-Breaks) # Mission San Luis Obispo de Tolosa ![Mission San Luis Obispo de Tolosa is a Spanish mission founded in 1772 by Father Junípero Serra in the present-day city of San Luis Obispo, California. ](https://images.trvl-media.com/place/6046822/fc0b89de-5e14-4bc9-b104-a70a7c22c771.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mission San Luis Obispo de Tolosa is a Spanish mission founded in 1772 by Father Junípero Serra in the present-day city of San Luis Obispo, California. ](https://images.trvl-media.com/place/6046822/fc0b89de-5e14-4bc9-b104-a70a7c22c771.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Front entrance to the chapel of the Mission. ](https://images.trvl-media.com/place/6046822/0793bdd6-6447-4a7f-a40d-e100c546b141.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Celebrating Dia De Los Muertos. 11/1/14](https://images.trvl-media.com/place/6046822/7a016559-8c84-48c0-8b0f-8c49b6d770dd.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Front doors of the Mission. ](https://images.trvl-media.com/place/6046822/1f42e561-8db1-4dde-8917-2975becc8c13.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Mission San Luis Obispo de Tolosa Activities --- --- ### Popular places to visit ![A very old Adobe house near the Mission. ](https://images.trvl-media.com/place/6046822/a68ae6af-fd4c-4bf9-8761-aaa9bd132807.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Mission Plaza You can learn about the history of San Luis Obispo with a stop at Mission Plaza. Discover the acclaimed theatre scene in this family-friendly area or seek out the cycling trails. [](https://expedia.co.uk/Mission-Plaza-Downtown-San-Luis-Obispo.d553248621532640005.Attraction) ![The History Center of San Luis Obispo in California was built in 1905 as a Carnegie Library. , Shutterstock ID 220719421, Purchase Order: SP-1891 Wave 0, Client/Licensee:](https://images.trvl-media.com/place/553248621532640002/f1bbfb89-f562-4c40-8090-24d8ace1529c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### History Center of San Luis Obispo County You can spend an afternoon browsing the exhibits at History Center of San Luis Obispo County in San Luis Obispo. Stroll along the beautiful beaches or discover the beautiful sunsets in this family-friendly area. [](https://expedia.co.uk/History-Center-Of-San-Luis-Obispo-County-Downtown-San-Luis-Obispo.d553248621532640002.Attraction) ![B8ABM1 Ah Louis Store Chinese Historical Landmark Downtown San Luis Obispo California](https://images.trvl-media.com/place/553248635118923142/8e431b5d-5e9c-4a20-8486-0e558ac79846.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ah Louis Store You can spend an afternoon browsing the exhibits at Ah Louis Store during your trip to San Luis Obispo. Discover the area's top-notch restaurants and its acclaimed art galleries. [](https://expedia.co.uk/Ah-Louis-Store-Downtown-San-Luis-Obispo.d553248635118923142.Attraction) ![San Luis Obispo which includes outdoor art](https://images.trvl-media.com/place/553248621532640000/edf5f46b-54f5-4a1f-8526-5e34304d7b53.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Bubblegum Alley 3.5/5(7 reviews) Colorful pieces of chewed gum, some of which have been turned into art pieces, decorate the walls of this narrow lane. [](https://expedia.co.uk/Bubblegum-Alley-Downtown-San-Luis-Obispo.d553248621532640000.Attraction) ![BG04CA San Luis Obispo Children's Museum, San Luis Obispo, California, United States of America](https://images.trvl-media.com/place/553248621532640003/58e038bc-2dac-475f-abe0-c344a2a128f1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Luis Obispo Children's Museum Enjoy a trip to San Luis Obispo Children's Museum and popular activities such as cycling in San Luis Obispo. Wander through the beautiful beaches and seaside in this family-friendly area. [](https://expedia.co.uk/San-Luis-Obispo-Childrens-Museum-Downtown-San-Luis-Obispo.d553248621532640003.Attraction) ![SanLuisObispo_SanLuisObispoCountyLibrary_553248621555611788_01](https://images.trvl-media.com/place/553248621555611788/4e3fbeed-6fda-4ef8-8253-d99f7ba83011.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Luis Obispo County Library After visiting San Luis Obispo County Library, make a plan to see the other sights and activities in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [](https://expedia.co.uk/San-Luis-Obispo-County-Library-Downtown-San-Luis-Obispo.d553248621555611788.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Mission San Luis Obispo de Tolosa [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=2026-02-11&endDate=2026-02-12)[11 Feb - 12 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=2026-02-11&endDate=2026-02-12) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=2026-02-12&endDate=2026-02-13)[12 Feb - 13 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=2026-02-12&endDate=2026-02-13) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6089181&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) ![Quality Suites Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Quality Suites Downtown San Luis Obispo 1631 Monterey St San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![Madonna Inn](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Madonna Inn 100 Madonna Road San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown 1845 Monterey St. San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Hotel San Luis Obispo](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel San Luis Obispo 877 Palm Street San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) ![Garden Street Inn, A Kirkwood Collection Hotel](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/0fb1832a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Garden Street Inn, A Kirkwood Collection Hotel 1212 Garden St San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Garden-Street-Inn.h25838284.Hotel-Information) ![Avenue Inn Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/ec6a1c5f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Avenue Inn Downtown San Luis Obispo 345 Marsh St San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information) ![HOTEL CERRO, Autograph Collection](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/18ffa136_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL CERRO, Autograph Collection 1125 Garden St San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Granada Hotel & Bistro](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/780d8f20_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Granada Hotel & Bistro 1126 Morro St. San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Granada-Hotel-Bistro.h5531224.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Apple Farm 2015 Monterey St San Luis Obispo CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) [See all 1,095 properties in Mission San Luis Obispo de Tolosa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6089181) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.