Title: Midsize Isla Canas Car Hire | Expedia.co.uk ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Hire Companies in Isla Canas [Become a member for free](https://expedia.co.uk/member-price?rfrr=TG.CM) and get more than just a booking discount. Members also earn points towards their next trip. Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more. Enjoy maximum flexibility with penalty-free cancellation on most car rentals. ## Find Cheap Midsize Car Deals for Isla Canas \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car hire in Isla Canas [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Isla%20Canas,%20Los%20Santos,%20Panama&dpln=6286066&date1=22/09/2025&date2=24/09/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ## Midsize Car Hire Information | Car type: | Midsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | - Experience new places with Expedia ### Find Popular Airports close to Isla Canas - [Car hire at Tocumen Intl. Airport (PTY)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Tocumen-Intl.d5854288.Car-Hire-Guide) ### Find Other Car Classes in Isla Canas - [Mini car hire in Isla Canas](https://expedia.co.uk/Mini-Car-Rentals-In-Isla-Canas.d6286066-tMini.Car-Rental-Guide-Class) - [Economy car hire in Isla Canas](https://expedia.co.uk/Economy-Car-Rentals-In-Isla-Canas.d6286066-tEconomy.Car-Rental-Guide-Class) - [Compact car hire in Isla Canas](https://expedia.co.uk/Compact-Car-Rentals-In-Isla-Canas.d6286066-tCompact.Car-Rental-Guide-Class) - [Standard car hire in Isla Canas](https://expedia.co.uk/Standard-Car-Rentals-In-Isla-Canas.d6286066-tStandard.Car-Rental-Guide-Class) - [Fullsize car hire in Isla Canas](https://expedia.co.uk/Fullsize-Car-Rentals-In-Isla-Canas.d6286066-tFullsize.Car-Rental-Guide-Class) - [Premium car hire in Isla Canas](https://expedia.co.uk/Premium-Car-Rentals-In-Isla-Canas.d6286066-tPremium.Car-Rental-Guide-Class) - [Luxury car hire in Isla Canas](https://expedia.co.uk/Luxury-Car-Rentals-In-Isla-Canas.d6286066-tLuxury.Car-Rental-Guide-Class) - [Convertible car hire in Isla Canas](https://expedia.co.uk/Convertible-Car-Rentals-In-Isla-Canas.d6286066-tConvertible.Car-Rental-Guide-Class) - [Minivan car hire in Isla Canas](https://expedia.co.uk/Minivan-Car-Rentals-In-Isla-Canas.d6286066-tMinivan.Car-Rental-Guide-Class) - [Van car hire in Isla Canas](https://expedia.co.uk/Van-Car-Rentals-In-Isla-Canas.d6286066-tVan.Car-Rental-Guide-Class) - [SUV car hire in Isla Canas](https://expedia.co.uk/SUV-Car-Rentals-In-Isla-Canas.d6286066-tSUV.Car-Rental-Guide-Class) - [Pickup car hire in Isla Canas](https://expedia.co.uk/Pickup-Car-Rentals-In-Isla-Canas.d6286066-tPickup.Car-Rental-Guide-Class) - [Sportscar car hire in Isla Canas](https://expedia.co.uk/Sportscar-Car-Rentals-In-Isla-Canas.d6286066-tSportscar.Car-Rental-Guide-Class) ### Expedia's Latest Trends Hotels - [İçmeler All-Inclusive Hotels](https://expedia.co.uk/Icmeler-Hotels-All-Inclusive-Hotel.0-0-d6054857-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Park Regis by Prince Singapore](https://expedia.co.uk/Singapore-Hotels-Park-Regis.h4018160.Hotel-Information) - [Lotte Hotel Hanoi](https://expedia.co.uk/Hanoi-Hotels-Lotte-Hotel-Hanoi.h8829295.Hotel-Information) - [The Eaton Oak](https://expedia.co.uk/St-Neots-Hotels-The-Eaton-Oak.h44795831.Hotel-Information) - [Novotel London Paddington](https://expedia.co.uk/London-Hotels-Novotel-London-Paddington.h2156327.Hotel-Information) - [Serviced Apartments Palma de Mallorca](https://expedia.co.uk/Palma-De-Mallorca-Apart-Hotels.d2829-aaApartHotels.Travel-Guide-Accommodation) - [Sol Nessebar Bay - All Inclusive](https://expedia.co.uk/Nessebar-Hotels-Sol-Nessebar-Bay-All-Inclusive.h1409491.Hotel-Information) - [Crete Golf Club Hotel](https://expedia.co.uk/Hersonissos-Hotels-Crete-Golf-Club-Hotel.h22748806.Hotel-Information) - [BelleVue Aquarius Aparthotel](https://expedia.co.uk/Tias-Hotels-BelleVue-Aquarius-Apartments.h904028.Hotel-Information) - [The Fence Gate Lodge](https://expedia.co.uk/Burnley-Hotels-The-Fence-Gate-Lodge.h20110122.Hotel-Information) - [Breathless Riviera Cancun Resort & Spa - Adults Only - All Inclusive](https://expedia.co.uk/Cancun-Hotels-Breathless-Riviera-Cancun-Resort-Spa-Adults-Only.h11868477.Hotel-Information) - [Inn at the Pier Pismo Beach, Curio Collection by Hilton](https://expedia.co.uk/San-Luis-Obispo-Hotels-Inn-At-The-Pier.h18675941.Hotel-Information) - [NH Boat Lagoon Phuket Resort](https://expedia.co.uk/Ko-Kaeo-Hotels-NH-Boat-Lagoon-Phuket-Resort.h1594143.Hotel-Information) - [Gamston Lock, Nottingham by Marston's Inns](https://expedia.co.uk/Nottingham-Hotels-The-Gamston-Lock-Lodge-By-Marstons-Inns.h33723742.Hotel-Information) Flights - [Loganair Exeter (EXT) to Edinburgh (EDI) flights](https://expedia.co.uk/lp/flight-routes/loganair-from-exeter-intl-to-edinburgh/lm/ext/edi) - [Flights to GOA](https://expedia.co.uk/Cheap-Flights-To-Sestri-Levante.d11087.Travel-Guide-Flights) - [LHR to AUR flights](https://expedia.co.uk/lp/flights/lhr/aur/london-to-aurillac) - [MAN to OSL flights](https://expedia.co.uk/lp/flights/man/osl/manchester-to-oslo) - [LHR to IST flights](https://expedia.co.uk/lp/flights/lhr/ist/london-to-istanbul) - [EBB to MBA flights](https://expedia.co.uk/lp/flights/ebb/mba/entebbe-to-mombasa) Cars - [Car rental in Rye](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Rye.d4769.Car-Hire-Guide) Activities - [Things to do in Lavris](https://expedia.co.uk/Things-To-Do-In-Lavris.d6125057.Travel-Guide-Activities) - [Things to do in Sorrento Coast](https://expedia.co.uk/Things-To-Do-In-Sorrento-Coast.d6059422.Travel-Guide-Activities) Packages - [Marbella Golf and Country Club](https://expedia.co.uk/Marbella-Golf-And-Country-Club-Marbella.d6259292.Attraction) - [Pearl Islands City Breaks](https://expedia.co.uk/Pearl-Islands.d553248623282268316.Holidays-City-Breaks) - [Greece City Breaks](https://expedia.co.uk/Greece.d67.Holidays-City-Breaks) - [Norway City Breaks](https://expedia.co.uk/Norway.d138.Holidays-City-Breaks) General - [Visit La Mata](https://expedia.co.uk/La-Mata.dx6250584) - [Visit Penton](https://expedia.co.uk/Penton.dx3000010215) - [Visit Retamar](https://expedia.co.uk/Almeria-Retamar.dx6048155) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](https://a.travel-assets.com/mad-service/qr-code/footer_qr/3_QR_FOOTER.png)