Mesotopos Holidays from £474

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Your Mesotopos Holiday

History, cuisine, art and more … It's all waiting for you with a Mesotopos holiday package. And with the ability to customise your city getaway, you know it'll be one that's tough to forget. Every trip to Mesotopos needs a well-thought-out itinerary. Fill yours with major attractions such as Naturist Beach, Ágios Panteleímon and Podarás. Browse Expedia's wide range of travel options and start planning your ultimate holiday to Mesotopos now.

Top Mesotopos Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Delfinia

Hotel Delfinia

3 out of 5
Save 100% on your flight
Price was £743, price is now £474 per person
£474
per person
8 Sept - 15 Sept
found 1 day ago
Return direct flight included
Birmingham (BHX) to Mytilene (MJT)
7.6/10 Good! (115 reviews)

Aeolian Village Beach Resort

Aeolian Village Beach Resort

4 out of 5
Price was £918, price is now £702 per person
£702
per person
21 Sept - 27 Sept
found 1 day ago
Return direct flight included
Bristol (BRS) to Mytilene (MJT)
9/10 Wonderful! (25 reviews)
A lovely place to stay! The hotel rooms were super modern, aircon worked well, small fridge, hairdryer, shower was good, bed was comfy, balcony was nice! The staff were amazing too, masseuse did an excellent massage for my partners back! Pool was really nice, always a life guard on duty, plenty of sun loungers too so no fighting over them. Breakfast was excellent, brilliant choice and all the staff had smiles on their faces, definitely going to come back next year!

Reviewed on 25 May 2026

Mesotopos Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Population
770
Max Temp Winter
13ºC
Max Temp Summer
27ºC
Top Sights
Skala Kallonis Beach, Natural History Museum of the Lesvos Petrified Forest and Naturist Beach

Top hotels in Mesotopos

Aeolian Village Beach Resort

Aeolian Village Beach Resort

4 out of 5
Aeolian Village, Skala Eresos Lesvos Lesvos
8.8/10 Excellent! (26 reviews)
"A lovely place to stay! The hotel rooms were super modern, aircon worked well, small fridge, hairdryer, shower was good, bed was comfy, balcony was nice! The staff were amazing too, masseuse did an excellent massage for my partners back! Pool was really nice, always a life guard on duty, plenty of ..."

Reviewed on 25 May 2026

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Aeolian Village Beach Resort
Aegeon Hotel

Aegeon Hotel

3 out of 5
Skala Kallonis Lesvos
8.8/10 Excellent! (29 reviews)
"Nice Staff and bartender. Good concept in the middle of rural. Next to seaside. Best value for money."

Reviewed on 6 Sept 2024

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Aegeon Hotel
Clara Hotel

Clara Hotel

3 out of 5
Avlaki Petras Lesvos Lesvos Island
7.8/10 Good! (18 reviews)
Great hotel to stay in Petra! A++
"Great place to stay in Petra, great service, great location, great experience!"

Reviewed on 16 Aug 2024

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Clara Hotel
See all 153 properties in Mesotopos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Mesotopos travel package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in Mesotopos from just £474. And the more you bundle, the more you save. The holiday of your dreams has never been more affordable.
If I'm not able to travel, can I cancel my Mesotopos travel package?
You can. We realise life happens, so we're here to help if you have to make changes to your Mesotopos travel package. It may be possible to change or cancel your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to Mesotopos?
Book everything in one place with our Mesotopos travel packages. You'll find deals on flights, hotels and more that'll keep your budget happy and your adventurous side busy. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, there are endless opportunities to mix and match as you want.
Does Expedia offer Book Now, Pay Later Mesotopos holidays?
Your bank balance shouldn't stop you from escaping on holiday, so Expedia has worked out a solution to help. Now that we've formed a partnership with online lender Klarna, it's easier than ever to book a fantastic getaway without using up all your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your break. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's easy monthly instalment plans. If paying bite-sized amounts each month works for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay off your holiday in multiple transactions.
  • Low deposit holidays: Clicking on the "book now" button is easier with this option. Put down a small deposit on your booking and then start working on your travel plans.

Where should I stay in Mesotopos?
With so much to explore in Mesotopos, we suggest you book a hotel close to its attractions. Chroúsos, Vatrachiá and Podarás are some top ones to put on your itinerary.
What are the top hotels in Mesotopos?
Get your escape off to an excellent start by reserving a room at Theofilos Paradise Boutique Hotel. It's one of most popular properties in Mesotopos. Another cosy option is Sappho Hotel.
How far in advance should I book my Mesotopos holiday?
It all depends on the airline, but it's usually possible to browse through international airfares on Expedia up to 12 months in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper seat only weeks before departure dates.
What does an Expedia Mesotopos travel package include?
Hotels, flights and a cool set of wheels for all your fun road trip adventures. Simply pick and choose your preferred bundle and gain access to great discounts. Once you've made your booking, add on a few experiences and tours and watch your savings grow. When it comes to planning your Mesotopos break, you're the one in control!
What should I know before booking a Mesotopos travel package?
Our prices are always low. However, you'll enjoy even better deals when you book your flights, hotels and car rentals together. With an Expedia travel package, you'll get transparent pricing and a great range of choice.
Can I choose my airline with a Mesotopos Expedia travel package?
Yes, you're in charge. We offer more than 550 partner airlines across the globe, so you can design your Mesotopos escape according to your budget and needs.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.