Mesotopos Holidays from £500

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to £335 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Packages with flights are ATOL protected

Your Mesotopos Holiday

History, cuisine, art and more … It's all waiting for you with a Mesotopos holiday package. And with the ability to customise your city getaway, you know it'll be one that's tough to forget. Every trip to Mesotopos needs a well-thought-out itinerary. Fill yours with major attractions such as Naturist Beach, Ágios Panteleímon and Podarás. Browse Expedia's wide range of travel options and start planning your ultimate holiday to Mesotopos now.

Top Mesotopos Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat

5 out of 5
Save 100% on your flight
per person
9 Sept - 16 Sept
found 1 day ago
Return flight included
Athens (ATH) to Mytilene (MJT)
9/10 Wonderful! (33 reviews)
Great property with lovely views and friendly staff. Only issue is that the upper floors of some buildings are not handicapped accessible and you will have to carry luggage’s up the stairs. To avoid stay on one of the main buildings

Reviewed on 2 Aug 2024

The Loriet

The Loriet

4 out of 5
Save 100% on your flight
per person
9 Sept - 16 Sept
found 1 day ago
Return flight included
Athens (ATH) to Mytilene (MJT)
8.2/10 Very Good! (67 reviews)
Overall, a beautiful hotel - I was very pleased with my stay. The hotel is clean and well-kept and the staff is very courteous, and helpful. I will stay again without hesitation when Im back to Mytilene.

Reviewed on 12 Jul 2025

Aeolian Village Beach Resort

Aeolian Village Beach Resort

4 out of 5
Save 100% on your flight
per person
27 Sept - 4 Oct
found 1 day ago
Return flight included
London (LGW) to Mytilene (MJT)
9/10 Wonderful! (23 reviews)
Hotel has the Best sea/beach in the area. Turnover doesnt meet the expectation. Dinner was good, breakfast product quality was poor. 1.5 hour drive from the ferry. But overall it was a nice stay for us

Reviewed on 27 Jul 2025

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

4 out of 5
per person
9 Sept - 16 Sept
found 1 day ago
Return flight included
Athens (ATH) to Mytilene (MJT)
9.6/10 Exceptional! (149 reviews)
Hotel’s location is great. There are a lot of food/drinks options within minutes. It is located in a very lively part of the town, yet secluded for a quiet stay. The breakfast was also very good.

Reviewed on 13 Jul 2025

Elysion Hotel

Elysion Hotel

5 out of 5
per person
9 Sept - 16 Sept
found 1 day ago
Return flight included
Athens (ATH) to Mytilene (MJT)
9.2/10 Wonderful! (42 reviews)
Directly across from some great beaches, close to airport (never heard noise from the planes), 5 minute drive to center of Mytilene. The hotel is very clean, well-kept and everyone is very pleasant. It’s a great accommodation for Mytilene. We’ll definitely be going back.

Reviewed on 13 Aug 2023

Mesotopos Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Population
770
Max Temp Winter
13ºC
Max Temp Summer
27ºC
Top Sights
Skala Kallonis Beach, Natural History Museum of the Lesvos Petrified Forest and Naturist Beach

Top hotels in Mesotopos

Delfinia Hotel & Bungalows

Delfinia Hotel & Bungalows

Molyvos, Mythimna, North Aegean Islands, Lesvos
The price is £114 per night from 10 Aug to 11 Aug
£114
10 Aug - 11 Aug
includes taxes & fees
7.6/10 Good! (102 reviews)
"The stay was amazing. We had an issue with our next accommodation and the staff at the Delfinia let us book another night. One bummer was that the pool was broken the two nights we were there but it looked like a great place to hang out if it was working. It was apparently up and running the day ..."

Reviewed on 15 May 2025

Delfinia Hotel & Bungalows
Aeolian Village Beach Resort

Aeolian Village Beach Resort

4 out of 5
Aeolian Village, Skala Eresos, Lesvos, Lesvos
The price is £139 per night from 27 Aug to 28 Aug
£139
27 Aug - 28 Aug
includes taxes & fees
8.8/10 Excellent! (23 reviews)
Beautiful place to stay
"2 night stay. Lovely breakfast. Lots of choice. Pool enormous. Never felt overcrowded."

Reviewed on 18 Aug 2024

Aeolian Village Beach Resort
Omega Rooms Anaxos

Omega Rooms Anaxos

Main Road, Anaxos, Lesvos, Lesvos Island
8.2/10 Very Good! (14 reviews)
"Πολύ παλιές εγκαταστάσεις που έχουν χρόνια να συντηρηθούν και είναι μέσα στην μούχλα. Το βράδυ κλείναμε τις πόρτες διότι δεν είχαν σιτες και υπήρχαν κουνούπια. Το δωμάτιο μύριζε από την αποχέτευση πολύ άσχημα και δεν τολμουσαμε να ανοίξουμε τις πόρτες γιατί θα μας έτρωγαν τα κουνούπια. Δεν το προτείνω ..."

Reviewed on 6 Sep 2019

Get rates
Omega Rooms Anaxos
See all 134 properties in Mesotopos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Mesotopos travel package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in Mesotopos from just £500. And the more you bundle, the more you save. The holiday of your dreams has never been more affordable.
If I'm not able to travel, can I cancel my Mesotopos travel package?
You can. We realise life happens, so we're here to help if you have to make changes to your Mesotopos travel package. It may be possible to change or cancel your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to Mesotopos?
Book everything in one place with our Mesotopos travel packages. You'll find deals on flights, hotels and more that'll keep your budget happy and your adventurous side busy. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, there are endless opportunities to mix and match as you want.
Does Expedia offer Book Now, Pay Later Mesotopos holidays?
Your bank balance shouldn't stop you from escaping on holiday, so Expedia has worked out a solution to help. Now that we've formed a partnership with online lender Klarna, it's easier than ever to book a fantastic getaway without using up all your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your break. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's easy monthly instalment plans. If paying bite-sized amounts each month works for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay off your holiday in multiple transactions.
  • Low deposit holidays: Clicking on the "book now" button is easier with this option. Put down a small deposit on your booking and then start working on your travel plans.

Where should I stay in Mesotopos?
With so much to explore in Mesotopos, we suggest you book a hotel close to its attractions. Chroúsos, Vatrachiá and Podarás are some top ones to put on your itinerary.
What are the top hotels in Mesotopos?
Get your escape off to an excellent start by reserving a room at Theofilos Paradise Boutique Hotel. It's one of most popular properties in Mesotopos. Another cosy option is Sappho Hotel.
How far in advance should I book my Mesotopos holiday?
It all depends on the airline, but it's usually possible to browse through international airfares on Expedia up to 12 months in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper seat only weeks before departure dates.
What does an Expedia Mesotopos travel package include?
Hotels, flights and a cool set of wheels for all your fun road trip adventures. Simply pick and choose your preferred bundle and gain access to great discounts. Once you've made your booking, add on a few experiences and tours and watch your savings grow. When it comes to planning your Mesotopos break, you're the one in control!
What should I know before booking a Mesotopos travel package?
Our prices are always low. However, you'll enjoy even better deals when you book your flights, hotels and car rentals together. With an Expedia travel package, you'll get transparent pricing and a great range of choice.
Can I choose my airline with a Mesotopos Expedia travel package?
Yes, you're in charge. We offer more than 550 partner airlines across the globe, so you can design your Mesotopos escape according to your budget and needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.