Mesimeri Holidays from £426

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Your Mesimeri Holiday

The vibrant city of Mesimeri is calling your name. Discover its hot spots and hidden treasures with a Mesimeri holiday package that's custom made for you. During your trip to Mesimeri, take all the time you need for sightseeing. A popular place to start is Monastery of St. John Theologian. Expedia can help you escape your routine. Tailor your holiday to Mesimeri to suit your style of travel, whatever that may be!

Top Mesimeri Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
ONOMA Hotel

ONOMA Hotel

Vardaris
£426
per person
12 Dec - 17 Dec
found 10 hours ago
Return direct flight included
Manchester (MAN) to Thessaloniki (SKG)
9.4/10 Exceptional! (193 reviews)
The Modernist Thessaloniki

The Modernist Thessaloniki

Thessaloniki City Centre
£467
per person
12 Dec - 17 Dec
found 10 hours ago
Return direct flight included
Manchester (MAN) to Thessaloniki (SKG)
9.8/10 Exceptional! (647 reviews)
ON Residence

ON Residence

Thessaloniki City Centre
£500
per person
12 Dec - 17 Dec
found 10 hours ago
Return direct flight included
Manchester (MAN) to Thessaloniki (SKG)
9.8/10 Exceptional! (214 reviews)
Really one of the best hotels I've ever stayed in.

Reviewed on 30 Sept 2026

The Excelsior Small Luxury Hotels of the World

The Excelsior Small Luxury Hotels of the World

Thessaloniki City Centre
£451
per person
12 Dec - 17 Dec
found 10 hours ago
Return direct flight included
Manchester (MAN) to Thessaloniki (SKG)
9.6/10 Exceptional! (449 reviews)
Booked a suite for 4 nights. This is a Small Luxury Hotel so expectations are high and they should be. Enjoyed our stay and were pleased but with some disappointments. The hotel is in a great location. Parking is difficult but this is Europe and a European city so we expect this and were given options by the doorman/bellman who was most helpful. Check-in was warm and welcoming along with helpful. Any contact with reception prior to arrival was replied to and dinner reservations made for us. This is not a purpose built hotel but a retrofit. Therefore there are quirks. The suite was comfortable but the bathroom for a suite in #15 is small. Maybe this shouldn’t be categorized as a suite but a large room with a small bathroom. Given the large windows the room is dark, natural light is non existent in the bathroom and the lighting in both bathroom and room is quite poor. The bed is very comfortable but … when our linens were changed we experienced cigarette smoke smelling linens. Very very unpleasant. The A/C worked well along with wifi. Yes, the water was hot. In the shower we had the setting on cold to make it comfortable. An unusual problem for sure. Complimentary bottle of wine was appreciated along with bottled water daily. Goodies at reception a nice treat. Breakfast was good with a small buffet and menu for cooked to order. Maybe not an extensive buffet but the cooked to order items were nice to have.

Reviewed on 23 Sept 2026

September Hotel Thessaloniki

September Hotel Thessaloniki

£516
per person
12 Dec - 17 Dec
found 10 hours ago
Return direct flight included
Manchester (MAN) to Thessaloniki (SKG)
9.4/10 Exceptional! (104 reviews)

Mesimeri Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Closest Airport
Macedonia Airport (SKG)
Max Temp Winter
10ºC
Max Temp Summer
32ºC
Top Sights
Waterland, Thessaloniki Science Centre & Technology Museum and Thessaloniki Science Centre and Technology Museum

Top hotels in Mesimeri

NYX Hotel Thessaloniki

NYX Hotel Thessaloniki

1 Tsimiski Thessaloniki
Fully refundableReserve now, pay when you stay
£98
2 Nov - 3 Nov
includes taxes & fees
9.4/10 Exceptional! (101 reviews)
"Great location. Right in the center of town and walking distance from the old harbor, Aristotle square, food and shopping. Rooms are small but well equipped. A bit tight for a couple with luggage but manageable. Nice breakfast. No parking. Hotel offers valet parking for 30 EUR per night which is ..."

Reviewed on 22 Sept 2026

NYX Hotel Thessaloniki
The Met Hotel, a member of Design Hotels

The Met Hotel, a member of Design Hotels

48, 26th October Street Thessaloniki Central Macedonia
Fully refundableReserve now, pay when you stay
£161
28 Oct - 29 Oct
includes taxes & fees
9.2/10 Wonderful! (920 reviews)
"Amazing hotel!"

Reviewed on 28 Sept 2026

The Met Hotel, a member of Design Hotels
City Hotel Thessaloniki

City Hotel Thessaloniki

11 Komninon Street Thessaloniki Central Macedonia
£99
19 Oct - 20 Oct
includes taxes & fees
City Hotel Thessaloniki
See all 1,609 properties in Mesimeri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mesimeri attractions

Alpha Lavender

Enjoy an outing to Alpha Lavender during your stay in Mesimeri.
See properties

What to do in Mesimeri

Thessaloniki: Full-Day Bus Trip to Meteora

Thessaloniki: Full-Day Bus Trip to Meteora

£48
per adult
94% of travellers recommend
Thessaloniki: Full-Day Bus Trip to Meteora
Thessaloniki: Vergina and Pella Day Trip

Thessaloniki: Vergina and Pella Day Trip

£42
per adult
90% of travellers recommend
Thessaloniki: Vergina and Pella Day Trip
Kavala and Philippi Full Day Tour with Swim from Thessaloniki

Kavala and Philippi Full Day Tour with Swim from Thessaloniki

£34
per adult
100% of travellers recommend
Kavala and Philippi Full Day Tour with Swim from Thessaloniki
See all activities in Mesimeri

Frequently asked questions

How much does a Mesimeri travel package cost?
We make it simple to travel the world, with Mesimeri travel packages starting from just £426. You'll have the flexibility to bundle your favourite airlines, hotels and car rental. For the ultimate escape, why not add a couple of activities and tours to your itinerary?
If I'm not able to travel, can I cancel my Mesimeri travel package?
Plans can change in a flash, so yes, you can. You may be able to cancel or change your Mesimeri travel package at no cost within 24 hours of booking. For bookings older than that, you can still make the necessary changes, but your airline, hotel or car rental company may impose a charge. Looking for more information? Have a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to Mesimeri?
One of the simplest ways to save dollars (and time) is to combine your bookings with Expedia. Flights, hotels, activities and rental cars — we've got them all covered. Pick and choose a combination that suits your style and see your savings grow. Of course, a package deal is never one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotel options worldwide, which lets you customize your Mesimeri getaway.
Does Expedia offer Book Now, Pay Later Mesimeri holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has worked out a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a terrific getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your break. Consider one of these flexible payment options:
  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: Like the idea of paying for your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: When you want to grab an unbeatable deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you lock in your escape.
What are the top hotels in Mesimeri?
If it's your first visit to Mesimeri, book a room at Avalon Airport Hotel Thessaloniki or Hyatt Regency Thessaloniki. Both will make you feel at home and are popular options with many travellers.
How far in advance should I book my Mesimeri holiday?
Reward yourself with the biggest variety at the lowest prices by booking your Mesimeri adventure nice and early. Airlines generally publish flight tickets anywhere up to a year prior to departure, so secure your spot as soon as you can. That being said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream holiday!
What does an Expedia Mesimeri travel package include?
Much of that is up to you. You can choose from a range of Mesimeri packages, such as a flight, hotel and rental car. You can also book a flight and a hotel, or a flight and a rental car. Once you've made your booking, you can add the fun stuff like experiences and activities. Whatever your Mesimeri escape looks like, get ready to save!
What should I know before booking a Mesimeri travel package?
Whether it's relaxation or adventure you're chasing, a Mesimeri travel package lets you organise your escape your way. Plus, you'll score great discounts when you combine your accommodation with your rental car and flights. The more you bundle, the bigger the savings!
Can I choose my airline with a Mesimeri Expedia travel package?
Yes — that's the beauty of an Expedia travel package. You're in control. We have access to more than 550 airline partners all over the world, so you have loads of choice when putting together your Mesimeri getaway.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.