Title: Melrose Travel Guide: Best of Melrose, Florida Travel 2026 | Expedia.co.uk [Hotels in Melrose](https://expedia.co.uk/Melrose-Hotels.d3000431362.Travel-Guide-Hotels)[Holiday Rentals in Melrose](https://expedia.co.uk/Melrose-Holiday-Rentals.d3000431362.Travel-Guide-HolidayRentals)[Melrose Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Melrose.d3000431362.Car-Hire-Guide)[Melrose Holidays](https://expedia.co.uk/Melrose.d3000431362.Holidays-City-Breaks) # Melrose Travel Guide ## Tourist Guide ![Melrose](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Melrose Things to do - Top hotels in Melrose - Top Holiday Rentals in Melrose ![3 Bedroom House on Private Scenic Lake Mable](https://images.trvl-media.com/lodging/94000000/93160000/93156100/93156079/w906h683x59y0-4020ce62_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 3 Bedroom House on Private Scenic Lake Mable Melrose FL Stay at this holiday home in Melrose. Enjoy free Wi-Fi, a garden and laundry facilities. Popular attraction Santa Fe Lake is located nearby. 9.8/10 Exceptional! (13 reviews) Amenities were fine. Reviewed on 25 Feb 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=11%2F04%2F2026&endDate=12%2F04%2F2026&selected=93156079&PinnedHotelID=93156079&HadPinnedHotel=true®ionId=3000431362) [](https://expedia.co.uk/Hotel-Search?startDate=11%2F04%2F2026&endDate=12%2F04%2F2026&selected=93156079&PinnedHotelID=93156079&HadPinnedHotel=true®ionId=3000431362) ![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOM Hotel Gainesville, SureStay Collection by Best Western 3905 Sw 43Rd St Gainesville FL £72 5 Apr - 6 Apr includes taxes & fees Stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ... 8.4/10 Very Good! (1,860 reviews) Staff belligerent after just one mild criticism. Someone also entered my room & left it OPEN, no less, with “respect privacy” sign on the door. No clear delineation between lobby & breakfasting area for people with dogs. Bathroom super-functional, beds & pillows comfortable. Reviewed on 27 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=200755&PinnedHotelID=200755&HadPinnedHotel=true®ionId=3000431362) ![Country Inn & Suites by Radisson, Gainesville, FL](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Country Inn & Suites by Radisson, Gainesville, FL 4015 Sw 43rd St Gainesville FL £80 30 Mar - 31 Mar includes taxes & fees Stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ... 9.2/10 Wonderful! (1,737 reviews) It's always served me well. I stay here for the Florida Gators football game. Great place and good breakfast. Reviewed on 27 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=30%2F03%2F2026&endDate=31%2F03%2F2026&selected=1289043&PinnedHotelID=1289043&HadPinnedHotel=true®ionId=3000431362) [See all 855 properties in Melrose](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=29%2F03%2F2026&endDate=30%2F03%2F2026®ionId=3000431362) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![House in Melrose on Lake Sante Fe](https://images.trvl-media.com/lodging/101000000/100030000/100023700/100023634/e28101ba_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### House in Melrose on Lake Sante Fe Melrose FL Stay at this holiday home in Melrose. Enjoy a garden, laundry facilities and patios. Popular attraction Santa Fe Lake is located nearby. 10/10 Exceptional! (13 reviews) Beautiful quiet property on the lake and great for families. Reviewed on 10 Mar 2026 [](https://expedia.co.uk/Melrose-Hotels-House-In-Melrose-On-Lake-Sante-Fe.h100023634.Hotel-Information) ![3 Bedroom House on Private Scenic Lake Mable](https://images.trvl-media.com/lodging/94000000/93160000/93156100/93156079/w906h683x59y0-4020ce62_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 3 Bedroom House on Private Scenic Lake Mable Melrose FL Stay at this holiday home in Melrose. Enjoy free Wi-Fi, a garden and laundry facilities. Popular attraction Santa Fe Lake is located nearby. 9.8/10 Exceptional! (13 reviews) Amenities were fine. Reviewed on 25 Feb 2026 [](https://expedia.co.uk/Melrose-Hotels-3-Bedroom-House-On-Private-Scenic-Lake-Mable.h93156079.Hotel-Information) ![Lakefront Nature Escape! Cabin in Keystone Heights](https://images.trvl-media.com/lodging/37000000/36040000/36032300/36032293/2a2a6cc8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lakefront Nature Escape! Cabin in Keystone Heights Keystone Heights FL Stay at this cabin in Melrose. Enjoy patios, cable/satellite TV service and an in-room coffee maker. Popular attraction Santa Fe Lake is located nearby. 9.6/10 Exceptional! (48 reviews) Great stay Stay was great perfect location, beautiful view of the lake Reviewed on 16 Mar 2025 [](https://expedia.co.uk/Melrose-Hotels-Keystone-Heights-Lakefront-Cabin-Fire-Pit.h36032293.Hotel-Information) [See all properties in Melrose](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000431362&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Melrose hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431362&startDate=2026-03-28&endDate=2026-03-29)[28 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431362&startDate=2026-03-28&endDate=2026-03-29) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431362&startDate=2026-03-29&endDate=2026-03-30)[29 Mar - 30 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431362&startDate=2026-03-29&endDate=2026-03-30) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431362&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431362&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) ### Popular places to visit #### Single Vision Inc. Meet the animals who call Single Vision Inc. home during your trip to Melrose. While you're in the area, wander around the parks. [](https://expedia.co.uk/Single-Vision-Inc-Melrose.d553248621532654075.Attraction) ## Cities near Melrose ![Aerial View of Florida Lakes](https://images.trvl-media.com/place/6351663/3b2bf0e0-b7c8-4f5f-a972-a77a1a6bdb0c.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Keystone Heights - Cities near Melrose - Places of interest [Keystone Heights](https://expedia.co.uk/Keystone-Heights.dx6351663)[Earleton](https://expedia.co.uk/Earleton.dx3000345210) - [Shands at the University of Florida ](https://expedia.co.uk/Shands-At-The-University-Of-Florida-Gainesville.d6187967.Attraction) - [San Felasco Hammock Preserve State Park ](https://expedia.co.uk/San-Felasco-Hammock-Preserve-State-Park-Florida.d6128058.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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