Madre de Dios Region Holidays

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Your Madre de Dios Region Holiday

Choose one of our holiday packages to Madre de Dios Region and wander wherever your adventurous spirit leads you. If that includes Tambopata, the hiking and nature are just the start of the things you can look forward to in this exciting city. The easiest way to plan your trip to Madre de Dios Region is to start with its leading cities, which include Tambopata, Puerto Maldonado and Las Piedras. Whether you plan to travel on a shoestring or in the lap of luxury, Expedia are here to help you customise your next Madre de Dios Region holiday.

Top destinations in Madre de Dios Region

A river winding through a dense forest under a cloudy sky.
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Tambopata

Tambopata
A calm river with wooden docks and lush greenery in the background.
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Manu

Manu

Where to stay in Madre de Dios Region

Find the best Madre de Dios Region areas for the activities you enjoy most.

Chapajal

While Chapajal isn't home to many top sights, Puerto Maldonado Plaza de Armas and Puerto Maldonado Obelisk are some notable places to visit nearby.

Madre de Dios Region Essential Information

Language
Spanish
Currency
Peruvian sols
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Padre Aldamiz Intl. Airport (PEM)
Top Sights
Tambopata National Reserve, Sandoval Lake and Manu National Park

Top hotels in Madre de Dios Region

IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo Tambopata Madre de Dios
The price is £147 per night from 1 Nov to 2 Nov
£147
1 Nov - 2 Nov
9.2/10 Wonderful! (25 reviews)
"We had the best stay! We booked the airport transfers, tours, and all meals, and everything exceeded our expectations. The food was incredible, and the rooms were comfortable, clean, and had wonderful AC—a true relief after a day of exploring! All of the staff were so helpful, welcoming, and courteous. ..."

Reviewed on 13 Oct 2026

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Tambopata Edosikiana Ecolodge

Tambopata Edosikiana Ecolodge

3 out of 5
Av. Aeropuerto S/N Comunidad Infierno Tambopata Tambopata Madre de Dios
2/10 (1 review)
"Staff was helpful Otherwise nothing was amazing. Room was not too clean, food was okayish, no choice was given."

Reviewed on 15 Jun 2026

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Tambopata Edosikiana Ecolodge
Inkaterra Reserva Amazonica

Inkaterra Reserva Amazonica

4 out of 5
Madre De Dios River Km. 15 Las Piedras Madre de Dios
9.4/10 Exceptional! (54 reviews)
"Only remark is to enable electricity in the rooms during the day without interruption for fan and charging phones (solar panel with batteries for example). It was very hot and hard to rest in the room"

Reviewed on 19 Jul 2026

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Inkaterra Reserva Amazonica
See all 60 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Family Friendly Holidays

Frequently asked questions

How much does a Madre de Dios Region travel package cost?
Customize your Madre de Dios Region travel package from an affordable . Pick from any combination of rental cars, flights and hotels to craft the trip of your dreams. Be sure to add on a few experiences or activities!
If I'm not able to travel, can I cancel my Madre de Dios Region travel package?
Because we understand life can be unpredictable, the answer is yes. For more information, check out our Customer Service Portal. But generally speaking, if you've booked your Madre de Dios Region travel package in the last 24 hours, you may be able to cancel or change it with no penalties. Your hotel, airline or car rental company may charge a fee if you made your booking a while ago.
How do I get a cheap travel package to Madre de Dios Region?
You'll save a pile of money if you bundle your flights, car rentals and hotels into a Madre de Dios Region travel package. Sometimes cheap means fewer choices. But that's not the case with Expedia. We offer over 550 air carriers and 1,000,000 properties all over the world, so you'll always have plenty of options to choose from. Want to save even more? Add some exciting activities to your package deal and unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
Does Expedia offer Book Now, Pay Later Madre de Dios Region holidays?
Your bank balance shouldn't stop you from going on holiday, so Expedia has worked out a solution to help. Thanks to our partnership with online lender Klarna, it's easier than ever to book a terrific getaway without eating away at your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna offers just that! Paying in easy monthly instalments will make your getaway dreams come true.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay for your holiday in multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, choose a low deposit holiday payment plan with Klarna.

What are the top hotels in Madre de Dios Region?
Hotel Pueblo Verde and Sotupa Eco House know how to make their guests feel welcome in Tambopata. If you also plan to get to Las Piedras, have a look at Hotel Pueblo Verde and Sotupa Eco House. Both are top picks with travellers.
How far in advance should I book my Madre de Dios Region holiday?
While prices fluctuate, we generally advise booking your seats as soon as possible. Many international airfares can be found on Expedia up to 12 months in advance. If circumstances have left you booking late, you may still get lucky. Cheap journeys to Madre de Dios Region sometimes emerge only weeks before departure.
What does an Expedia Madre de Dios Region travel package include?
You can select from a combination of rental cars, flights and hotels. Once you've made your booking, you can add the fun stuff like experiences and tours. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to putting together your dream Madre de Dios Region trip.
What should I know before booking a Madre de Dios Region travel package?
Design deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save precious cash just by combining your bookings. Whether you're heading away on a ski adventure or kicking back on a warm beach, your ideal holiday is only clicks away.
Can I choose my airline with a Madre de Dios Region Expedia travel package?
Yes, the choice is yours. We offer more than 550 partner airlines globally, so you can design your Madre de Dios Region trip according to your budget and travel needs.

Stay near popular Madre de Dios Region attractions

Puerto Maldonado Plaza de Armas

8.2/10 (22 reviews)
You can find out about the history of Puerto Maldonado with a trip to Puerto Maldonado Plaza de Armas. Wander the riverfront and forests while you're in the area.
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What to do in Madre de Dios Region

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

£416
per adult
Puerto Maldonado: 4-Day Tambopata Rainforest Tour
Puerto Maldonado : Trip to Yacumama Lake + sunset

Puerto Maldonado: Trip to Yacumama Lake + sunset

£27
per adult
Puerto Maldonado: Trip to Yacumama Lake + sunset
Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing

Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing

£71
per adult
100% of travellers recommend
Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing
See all activities in Madre de Dios Region

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.