Default HTG hotel image

Find hotels in Lyon, MS from £65

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Lyon hotels

A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.

1. Hampton Inn Clarksdale

Hampton Inn Clarksdale
2.5 star property
Clarksdale
8.4 out of 10, Very good, (420 reviews)
"Was perfect for our stay."
United States
Tami
The price is £106
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn Clarksdale
A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.

2. Travelers Hotel

Travelers Hotel
2.5 star property
Clarksdale
9.8 out of 10, Exceptional, (325 reviews)
"Friendly, helpful staff and set in a great location. Loved the shared kitchen and all its amenities. Would definitely stay here again."
United States
Suzanne
The price is £116
includes taxes & fees
8 Nov - 9 Nov
Travelers Hotel
A lobby with a chandelier, seating area, and a reception desk.

3. Quality Inn Clarksdale

Quality Inn Clarksdale
2.5 star property
Clarksdale
7.2 out of 10, Good, (799 reviews)
"The staff was top notch, way to go ladies!"
United States
Blu
The price is £68
includes taxes & fees
25 Nov - 26 Nov
Quality Inn Clarksdale
A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.

4. Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
2.5 star property
Clarksdale
6.0 out of 10, (438 reviews)
"Big mistake to stay here"
United States
Dave
The price is £65
includes taxes & fees
1 Nov - 2 Nov
Americas Best Value Inn & Suites Clarksdale
A wooden shelf with a Road Atlas, travel guides, a camera, and wine glasses.

5. Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel
2.0 star property
Clarksdale
9.6 out of 10, Exceptional, (112 reviews)
"Communication was excellent and the location is perfect."
United States
Jacqueline
The price is £98
includes taxes & fees
1 Nov - 2 Nov
Auberge Clarksdale Blues Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Lyon

A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.

Hampton Inn Clarksdale

2.5 star property
Clarksdale
View
A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.

Travelers Hotel

2.5 star property
Clarksdale
View
A lobby with a chandelier, seating area, and a reception desk.

Quality Inn Clarksdale

2.5 star property
Clarksdale
View
A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.

Americas Best Value Inn & Suites Clarksdale

2.5 star property
Clarksdale
View
A wooden shelf with a Road Atlas, travel guides, a camera, and wine glasses.

Auberge Clarksdale Blues Hostel

2.0 star property
Clarksdale
View
8.4
Very good
420 reviews
9.8
Exceptional
325 reviews
7.2
Good
799 reviews
6.0
438 reviews
9.6
Exceptional
112 reviews
The price is £106
includes taxes & fees
8 Nov - 9 Nov
The price is £116
includes taxes & fees
8 Nov - 9 Nov
The price is £68
includes taxes & fees
25 Nov - 26 Nov
The price is £65
includes taxes & fees
1 Nov - 2 Nov
The price is £98
includes taxes & fees
1 Nov - 2 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • No WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • No Parking
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Lyon Hotel Reviews

Travelers Hotel

Travelers Hotel

10/10 Excellent
"Know Lots of steps to upstairs rooms….request first floor if hauling luggage up long flight of stairs is not your thing. Great common area with kitchen availability."
karen 1-night trip
Posted 4 hours ago
Travelers Hotel

More cheap stays in Lyon

Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS
The price is £65 per night from 2 Nov to 3 Nov
£65
2 Nov - 3 Nov
includes taxes & fees

Frequently asked questions

What is the best area to stay in Lyon?
The best area to stay in Lyon, Mississippi, is near the intersection of Highway 61 and Highway 322, particularly around the few accommodations available in the town itself.

This area is the most convenient for visitors as it's where you'll find the limited lodging options and easy access to the main roads. Lyon is a very small town, so the "best" area is essentially the most central and accessible part.

For solo travellers or couples passing through, staying directly in Lyon offers a practical stop.
When is the best time to go to Lyon?
The best time to visit Lyon, Mississippi, is during the spring (April to May) and autumn (September to October) months.

These periods offer pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the area comfortably. You'll find it's a great time for outdoor activities without the intense heat of summer or the cooler temperatures of winter.

Spring brings blooming flora and a generally uplifting atmosphere, great for those who enjoy strolls and appreciating natural beauty.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lyon.
How much is the nightly rate at a Lyon hotel?
Prices for hotels in Lyon often vary, but you can find a great deal from £65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia