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Check prices for these dates

Tonight
15 Sept - 16 Sept
Tomorrow
16 Sept - 17 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

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Our top choices for Lyon hotels

A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.
A window with the text "TRAVELERS HOTEL" and a reflection of a bar area with stools and a counter.
A dining area with a table and four chairs, a potted plant, and a lamp.
A spacious lobby with a green door, a beige sofa, a wooden coffee table, and a large window offering a view of the outside.

1. Travelers Hotel

Travelers Hotel
Clarksdale
United States
Carl
£117
includes taxes & fees
20 Sept - 21 Sept
Travelers Hotel
A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.
A Hampton Inn with a modern beige facade, a flag, and a covered entrance.
A rectangular swimming pool with a blue interior, surrounded by a brick border and a metal railing.
A reception desk with a wooden finish, a framed welcome sign, and a lamp.

2. Hampton Inn Clarksdale

Hampton Inn Clarksdale
Clarksdale
United States
Judy
£108
includes taxes & fees
23 Sept - 24 Sept
Hampton Inn Clarksdale
A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.
A compact black refrigerator with a microwave on top, a small wooden table, and a potted plant.
A dining area with a table, chairs, a television, a cabinet, and a floral centerpiece.
A hotel room with two beds, a desk with a computer, a chair, a television, and two lamps.

3. Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
Clarksdale
United States
Darren
£64
includes taxes & fees
16 Sept - 17 Sept
Americas Best Value Inn & Suites Clarksdale
A lobby with seating, a reception desk, a plant, and a painting on the wall.
A hotel room with a bed, a sofa, a small table, and a window with curtains.
A hotel room with a bed, bedside tables, a desk, and a chair.
A lobby with two armchairs, a round ottoman, a small table with two lamps, and a framed artwork on the wall.

4. Quality Inn Clarksdale

Quality Inn Clarksdale
Clarksdale
United States
Blu
£64
includes taxes & fees
8 Oct - 9 Oct
Quality Inn Clarksdale
A bar area with wooden bar stools and shelves with bottles and glasses.
A shower area with three white shower curtains tied to a central rod, beige tiled walls, and a tiled floor.
A hallway with a white wall, wooden floor, a sofa, a lamp, and a rug.
A bar area with two leather barstools, a brick wall, a wooden cabinet with glassware, and a brick oven.

5. Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel
Clarksdale
United States
Rydell
£89
includes taxes & fees
16 Sept - 17 Sept
Auberge Clarksdale Blues Hostel
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Top Lyon Hotel Reviews

Hampton Inn Clarksdale

Hampton Inn Clarksdale

10/10 Excellent
"Breakfast was very good."
Maurice 1-night trip
Posted 7 days ago
Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

10/10 Excellent
"Stayed to attend Reds Fest. Great location, not far from the MLK Park, Reds, and Ground Zero. Lobby and rooms clean, common kitchen accessible for guest. Check in is all automated, so no front desk. Owner very nice person"
Curtis 1-night trip
Posted 8 days ago
Travelers Hotel
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

10/10 Excellent
"Very clean, very nice and comfortable, very pet friendly, washer and dryer worked well, host was very attentive, and property is very close to everything in clarksdale!!Very pleased!!"
STEPHANIE P. 3-night trip
Posted 2 weeks ago
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS
Sunset Log Cabin

Sunset Log Cabin

10/10 Excellent
"Libby is a very professional and responsive host. The place was perfect for my needs, allowed my dog, easy to get to town, yet also a bit on outskirts so not surrounded by hustle and bustle. Pleasant, rustic vibe, relaxing, and would definitely stay again."
Matt S. 2-night trip
Posted 3 weeks ago
Sunset Log Cabin
Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

10/10 Excellent
"My go to place to stay when I visit Clarksdale. Has everything you need. Very quiet street and close to everything downtown."
KENNETH M. 5-night trip
Posted 1 month ago
Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

10/10 Excellent
"There was a total of 15 of us, Siblings with our children. We had a great time with thoroughly enjoyed the pool and all the laughter just hanging out playing games and eating meals together. A great place for a lot of people."
Marietta M. 2-night trip
Posted 1 month ago
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

10/10 Excellent
"My first time in a hostel and was sort of dreading it, but it was lovely. Shared bathroom was more like a locker room. Great location to walk everywhere."
Shelly 2-night trip
Posted 1 month ago
Auberge Clarksdale Blues Hostel
Only a mile from historic downtown Clarksdale!

Only a mile from historic downtown Clarksdale!

10/10 Excellent
"Great spot. Excellent host"
Todd G. 2-night trip
Posted 2 months ago
Only a mile from historic downtown Clarksdale!
Cottage on riverbank one mile from Clarksdale in gated community

Cottage on riverbank one mile from Clarksdale in gated community

10/10 Excellent
"The property was very clean, comfortable and check in was so easy, the hospitality was amazing, we really enjoyed ourselves and will be visiting again!!!"
Bridget I. 3-night trip
Posted 2 months ago
Cottage on riverbank one mile from Clarksdale in gated community

More cheap stays in Lyon

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
£64
8 Oct - 9 Oct
includes taxes & fees
Quality Inn Clarksdale
Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS
£64
16 Sept - 17 Sept
includes taxes & fees
6/10 (432 reviews)
Americas Best Value Inn & Suites Clarksdale
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

164 Delta Ave Clarksdale MS
£89
16 Sept - 17 Sept
includes taxes & fees
9.6/10 Exceptional! (110 reviews)
Auberge Clarksdale Blues Hostel
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
£108
23 Sept - 24 Sept
includes taxes & fees
8.2/10 Very good! (406 reviews)
Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
£117
20 Sept - 21 Sept
includes taxes & fees
9.8/10 Exceptional! (318 reviews)
Travelers Hotel
High Cotton Condos

High Cotton Condos

249 Delta Ave Clarksdale MS
Get rates
8.8/10 Excellent! (6 reviews)
High Cotton Condos

Frequently asked questions

What is the best area to stay in Lyon?
The best area to stay in Lyon, Mississippi, is near the intersection of Highway 61 and Highway 322, particularly around the few accommodations available in the town itself.This area is the most convenient for visitors as it's where you'll find the limited lodging options and easy access to the main roads. Lyon is a very small town, so the "best" area is essentially the most central and accessible part.For solo travellers or couples passing through, staying directly in Lyon offers a practical stop.
When is the best time to go to Lyon?
The best time to visit Lyon, Mississippi, is during the spring (April to May) and autumn (September to October) months.These periods offer pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the area comfortably. You'll find it's a great time for outdoor activities without the intense heat of summer or the cooler temperatures of winter.Spring brings blooming flora and a generally uplifting atmosphere, great for those who enjoy strolls and appreciating natural beauty.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lyon.
How much is the nightly rate at a Lyon hotel?
Prices for hotels in Lyon often vary, but you can find a great deal from £64 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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