Title: Hotels in Lyon, MS - Best Lyon Hotels from £62 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Lyon](https://expedia.co.uk/Lyon-Holiday-Rentals.d553248634998705303.Travel-Guide-HolidayRentals)[Lyon Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lyon.d553248634998705303.Car-Hire-Guide)[Lyon Holidays](https://expedia.co.uk/Lyon.d553248634998705303.Holidays-City-Breaks) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Lyon, MS from £62 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Lyon Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Lyon%2C+Mississippi%2C+United+States+of+America®ionId=553248634998705303&latLong=34.217887%2C-90.542043&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&amenities=PETS) ## Check prices for these dates Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634998705303&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634998705303&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634998705303&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634998705303&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Lyon hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Smoking | Desk, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/2606ec8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/3c683cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Smoking | Room amenity](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/09f42bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites Clarksdale Clarksdale 5.8/10 (390) "Everything was straight " £62 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/20bde9f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/55faa465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/de175126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Clarksdale Clarksdale 8.2/10 Very good (323) "We would stay there again." £106 includes taxes & fees 29 Oct - 30 Oct [](https://www.expedia.co.uk/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/cc59a6f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/7467caab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/2680ddf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/f4c15177.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelers Hotel Clarksdale 9.8/10 Exceptional (273) "Though a bit different, there was a great artsy feel to the hotel. " £121 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/82cb9926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/3e64df31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/94efd5b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Single Room | Memory-foam beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/fe1d9487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Auberge Clarksdale Blues Hostel Clarksdale 9.6/10 Exceptional (85) "great stay!" [](https://www.expedia.co.uk/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/e98cafb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/d6d31cff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/94b5934f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Clarksdale 7.2/10 Good (694) "Quiet and comfortable " £65 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=553248634998705303&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLyon-Hotels.d553248634998705303.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLyon-Hotels.d553248634998705303.Travel-Guide-Hotels) ## Top Lyon Hotel Reviews ![Hampton Inn Clarksdale](//images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08_y.jpg) ### Hampton Inn Clarksdale 10/10 Excellent "The staff was so pleasant and friendly The entire visit was very nice " [](https://expedia.co.uk/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) ![Travelers Hotel](//images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/cc59a6f5_y.jpg) ### Travelers Hotel 10/10 Excellent "Solid room, good service, great location. It was a relatively new hotel as if sept 2025 so some of the amenities were still being rolled out." [](https://expedia.co.uk/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information) ![Americas Best Value Inn & Suites Clarksdale](//images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8_y.jpg) ### Americas Best Value Inn & Suites Clarksdale 10/10 Excellent "Everything was straight " [](https://expedia.co.uk/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) ![Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale](//images.trvl-media.com/lodging/114000000/113250000/113243700/113243634/467c648a_y.jpg) ### Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale 10/10 Excellent "Was the perfect stay. Very nice accommodations. " [](https://expedia.co.uk/Clarksdale-Hotels-Charming-2-Bedroom-House-In-Lovely-Clarksdale-With-WiFi.h113243634.Hotel-Information) ![Auberge Clarksdale Blues Hostel](//images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/82cb9926_y.jpg) ### Auberge Clarksdale Blues Hostel 10/10 Excellent "I stay here every time I visit Clarkesdale. The bedscare clean and comfortable, rooms spacious and ckean, even a fan to use! I have never stayed in a hostel where the bathrooms are this ckean. They supply shampoo, deodorant, all you need." [](https://expedia.co.uk/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information) ![Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS](//images.trvl-media.com/lodging/102000000/101150000/101144900/101144826/12bbff96_y.jpg) ### Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS 10/10 Excellent "Jess the manager was great. Very quick to respond and help. The house was very clean and smelled amazing. We will be back!" [](https://expedia.co.uk/Clarksdale-Hotels-Get-To-BLUES-In-At-Rustys-Roost.h101144826.Hotel-Information) ## More cheap stays in Lyon ![Quality Inn](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 818 South State Street, Clarksdale, MS £65 19 Oct - 20 Oct includes taxes & fees 7.2/10 Good! (693 reviews) [](https://expedia.co.uk/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information) ![Hampton Inn Clarksdale](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Clarksdale 15000 New Africa Rd, Clarksdale, MS £106 29 Oct - 30 Oct includes taxes & fees 8/10 Very Good! (320 reviews) [](https://expedia.co.uk/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) ![Americas Best Value Inn & Suites Clarksdale](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Americas Best Value Inn & Suites Clarksdale 350 South State Street, Clarksdale, MS £62 13 Oct - 14 Oct includes taxes & fees 5.8/10 (390 reviews) [](https://expedia.co.uk/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) ![Travelers Hotel](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/cc59a6f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Travelers Hotel 212 3rd St, Clarksdale, MS £121 2 Nov - 3 Nov includes taxes & fees 9.6/10 Exceptional! (273 reviews) [](https://expedia.co.uk/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information) ![Auberge Clarksdale Blues Hostel](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/82cb9926_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Auberge Clarksdale Blues Hostel 164 Delta Ave, Clarksdale, MS [Get rates](https://expedia.co.uk/Hotel-Search?startDate=26%2F10%2F2025&endDate=27%2F10%2F2025&selected=38924451&PinnedHotelID=38924451&HadPinnedHotel=true®ionId=553248634998705303) 9.6/10 Exceptional! (85 reviews) [](https://expedia.co.uk/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information) ![High Cotton Condos](https://images.trvl-media.com/lodging/8000000/7380000/7374500/7374432/7583d1b4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### High Cotton Condos 249 Delta Ave, Clarksdale, MS [Get rates](https://expedia.co.uk/Hotel-Search?startDate=26%2F10%2F2025&endDate=27%2F10%2F2025&selected=7374432&PinnedHotelID=7374432&HadPinnedHotel=true®ionId=553248634998705303) [](https://expedia.co.uk/Clarksdale-Hotels-High-Cotton-Condos.h7374432.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in Lyon? > [Quality Inn](https://www.expedia.co.uk/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information), located 3.2 mi (5.2 km) from the heart of Lyon, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are [Hampton Inn Clarksdale](https://www.expedia.co.uk/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) and [Americas Best Value Inn & Suites Clarksdale](https://www.expedia.co.uk/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248634998705303), or [vacation rentals in Lyon](https://www.expedia.co.uk/Lyon-Holiday-Rentals.d553248634998705303.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Lyon has to offer? > [The Sunflower Penthouse on the River in Clarksdale](https://www.expedia.co.uk/Clarksdale-Hotels-The-Sunflower-Penthouse-On-The-River-In-Clarksdale.h87715200.Hotel-Information): This holiday home rental outside of Lyon is located on a river, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. Make the most of books in this rental home to help you unwind. See all [vacation rentals in Lyon](https://www.expedia.co.uk/Lyon-Holiday-Rentals.d553248634998705303.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Lyon, will I receive a refund? > Yes! Most hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248634998705303&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Lyon. ### What is staying in Lyon like? > Travellers to Lyon will find plenty to explore and enjoy. There are 34 hotels and other accommodation options in the surrounding area. Find out more about [Lyon](https://www.expedia.co.uk/Lyon.dx553248634998705303). ### What should I do while I'm visiting Lyon? > Places to visit in the wider area include [Hambone Art Gallery](https://www.expedia.co.uk/Hambone-Art-Gallery-Clarksdale.d553248621561877046.Attraction), [Delta Blues Museum](https://www.expedia.co.uk/Delta-Blues-Museum-Clarksdale.d6263361.Attraction) and [Rock N' Roll & Blues Heritage Museum](https://www.expedia.co.uk/Rock-N-Roll-Blues-Heritage-Museum-Clarksdale.d553248621533115347.Attraction). You'll also find [Carnegie Public Library](https://www.expedia.co.uk/Carnegie-Public-Library-Clarksdale.d553248621586103761.Attraction) and [Ground Zero Blues Club](https://www.expedia.co.uk/Ground-Zero-Blues-Club-Clarksdale.d950930516842983424.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Lyon guide](https://www.expedia.co.uk/Lyon.dx553248634998705303). ### What's the weather like in Lyon? > The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 8°C. 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Tunica](https://www.expedia.co.uk/Goldcar-Keyn-Go-Car-Rentals-In-Robinsonville-Tunica.d6048540-c1044.Car-Rental-Guide-Suppliers) - [Island Car Rentals Rental Cars in Robinsonville - Tunica](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Robinsonville-Tunica.d6048540-c1132.Car-Rental-Guide-Suppliers) - [Ok Mobility Rental Cars in Robinsonville - Tunica](https://www.expedia.co.uk/OK-Mobility-Car-Rentals-In-Robinsonville-Tunica.d6048540-c1057.Car-Rental-Guide-Suppliers) - [Ss Travels Rental Cars in Robinsonville - Tunica](https://www.expedia.co.uk/SS-Travels-Car-Rentals-In-Robinsonville-Tunica.d6048540-c1112.Car-Rental-Guide-Suppliers) - [Car hire in Sixt Freilassing, Mnchener Str. 53](https://www.expedia.co.uk/Sixt-at-Freilassing.v55209.Car-Rental-Guide-Location) - [Courtland Holiday Rentals](https://www.expedia.co.uk/Courtland-Holiday-Rentals.d553248635975870279.Travel-Guide-HolidayRentals) - [Duncan Holiday Rentals](https://www.expedia.co.uk/Duncan-Holiday-Rentals.d553248635149961086.Travel-Guide-HolidayRentals) - 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