The Best Hotels Closest to Lake Issaqueena in Central - 2026 Updated Prices

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Our top choices for Lake Issaqueena hotels

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A lobby with seating areas, a reception desk, and a patterned wall.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

1. Best Western Plus Clemson Hotel & Conference Center

4.2 mi from Lake Issaqueena

Julio

£83

includes taxes & fees

31 Aug - 1 Sept

A modern kitchen with a microwave, coffee maker, and bar stools.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent sign, well-maintained landscaping, and a clear view of the entrance.

A hotel lobby with a reception desk, a large tiger mural, a TV, and a seating area with a blue sofa.

A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

2. Comfort Inn & Suites Clemson - University Area

4.1 mi from Lake Issaqueena

Anita

£86

includes taxes & fees

20 Sept - 21 Sept

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

A modern lobby with a reception desk, seating area, and a vending machine.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

3. Fairfield Inn & Suites Seneca Clemson Univ Area

6.6 mi from Lake Issaqueena

Ronald

£97

includes taxes & fees

6 Sept - 7 Sept

A cabin with a large window, surrounded by trees.

A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

4. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

9.8 mi from Lake Issaqueena

Nirumol

£107

includes taxes & fees

2 Sept - 3 Sept

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A reception area with a counter, chairs, and a patterned rug.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

5. Hampton Inn & Suites Seneca-Clemson Area

5.3 mi from Lake Issaqueena

Georgina

£96

includes taxes & fees

3 Sept - 4 Sept

6. Holiday Inn Express & Suites Clemson by IHG

4.4 mi from Lake Issaqueena

Angela

£90

includes taxes & fees

7 Sept - 8 Sept

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A hotel room with two beds, a desk, a television, and a clock on the wall.

7. Inn @ Clemson

4.1 mi from Lake Issaqueena

Terry

£63

includes taxes & fees

29 Aug - 30 Aug

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

8. Best Western Seneca-Clemson

6 mi from Lake Issaqueena

Michelle

£82

includes taxes & fees

31 Aug - 1 Sept

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A hotel lobby with a long corridor, seating areas, and a reception desk.

A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

A brick building with a sign reading "The Inn at Patrick Square".

9. The Inn at Patrick Square

5.7 mi from Lake Issaqueena

Beatriz

£122

includes taxes & fees

30 Aug - 31 Aug

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

10. Quality Inn Seneca US-123

8.4 mi from Lake Issaqueena

Anthony

£66

includes taxes & fees

6 Sept - 7 Sept

A modern bar area with a menu board, bar stools, and a countertop with various items.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

A modern dining area with a bar, bar stools, and a patterned rug.

11. Courtyard Marriott Clemson

4.5 mi from Lake Issaqueena

Gargi

£103

includes taxes & fees

8 Sept - 9 Sept

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

A reception desk with a vase of flowers, framed pictures, and a printer.

A gazebo with a tiled roof and a surrounding gravel area.

12. Days Inn by Wyndham Clemson

4.4 mi from Lake Issaqueena

David

£65

includes taxes & fees

31 Aug - 1 Sept

A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

A modern kitchen with white cabinets, a large TV, wooden flooring, and a dining area with a bench and coffee table.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

13. Carolina Camp Cedar

12.6 mi from Lake Issaqueena

Katlynn

£195

includes taxes & fees

31 Aug - 1 Sept

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

A swimming pool with lounge chairs and a fence, surrounded by trees.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

14. Days Inn by Wyndham Seneca / Clemson Area

7.9 mi from Lake Issaqueena

John

£66

includes taxes & fees

30 Aug - 31 Aug

A modern kitchen area with a bar counter and seating.

A modern bar area with high stools and a poolside view.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

A vending area with snacks and beverages, including chips and soda.

15. Hampton Inn Clemson-University Area

3.4 mi from Lake Issaqueena

DOUGLAS

£86

includes taxes & fees

6 Sept - 7 Sept

A kitchen with a coffee maker, microwave, and refrigerator.

A red brick building with a white porch and columns, a door, and windows.

A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.

A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.

16. Rodeway Inn & Suites Walhalla

11 mi from Lake Issaqueena

michael

£63

includes taxes & fees

27 Sept - 28 Sept

A green RV parked in a forest with a picnic table and a covered area.

A rectangular swimming pool with a tiled deck, surrounded by lounge chairs and umbrellas, and a covered seating area.

A living room with a fireplace, sofa, television, and ceiling fan.

A covered outdoor seating area with a table and chairs, large windows, and a wooden lattice fence.

17. The Point At Lake Hartwell

12.3 mi from Lake Issaqueena

Douglas

£95

includes taxes & fees

28 Sept - 29 Sept

A hotel lobby with a reception desk, seating area, and a view of the street outside.

A modern kitchen with wooden cabinets, a built-in dishwasher, a large window with a view of the outside, and a flat-screen TV mounted on the wall.

A reception area with a desk, two chairs, a large water dispenser, and a painting on the wall.

A compact bathroom with a white sink, a mirror, a black refrigerator, and a towel rack with wooden hangers.

18. Econo Lodge Clemson - University Area

4.7 mi from Lake Issaqueena

Khaled

£67

includes taxes & fees

4 Sept - 5 Sept

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Compare popular hotels close to Lake Issaqueena

Property	Property class	Guest rating
Best Western Plus Clemson Hotel & Conference Center	8.0 Very good 1,004 reviews	View
Comfort Inn & Suites Clemson - University Area	8.4 Very good 1,002 reviews	View
Fairfield Inn & Suites Seneca Clemson Univ Area	9.4 Exceptional 264 reviews	View
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy	9.8 Exceptional 101 reviews	View
Hampton Inn & Suites Seneca-Clemson Area	9.2 Wonderful 738 reviews	View

Top Lake Issaqueena Hotel Reviews

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Great hotel. Beautiful, fresh decor. Loved the rooftop and the 3rd floor bar area and terrace. Right in the middle of all the action. A great place to stay if you are touring/visiting Clemson University."

Inn @ Clemson

10/10 Excellent

"It’s"

Clemson Barndominium -close to University and lakes

10/10 Excellent

"The 'barndominium' had everything we needed. It was cozy, clean, and close to Clemson University. It was so nice to rest comfortably before moving my student in to his dorm. I hope to stay again in the future."

Best Western Plus Clemson Hotel & Conference Center

8/10 Good

"The front desk woman was super sweet and welcoming. The hotel itself has a lot of character and is pretty cool, although it could definitely use some updating. Our room had a musty smell, and the bathroom floors—especially in the corners—could use a deeper cleaning. Overall, we just needed an affordable place to sleep for one night while visiting Clemson for a tour, and for around $100, it did the job. Not fancy, but perfectly fine for a quick overnight stay."

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"room was clean and modern, very nice"

Wraparound Porch Downtime, Memorial Stadium 5 Mi

10/10 Excellent

"Great property - it felt homey - like staying at a good friends house. Traveled as family including children - college age and a toddler. Everyone had room and peaceful spaces to themselves. Convenient to get to Clemson and also surrounding outdoor activites. Would look forward to booking again."

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

10/10 Excellent

"The location was ideal for Clemson move-in and the condo was very roomy for our family. A great place to stay! Caden was an excellent host!"

Hampton Inn Clemson-University Area

8/10 Good

"The hotel rooms need updating, but the hotel is clean, the breakfast is good, and the staff is very friendly."

NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football

10/10 Excellent

"Very clean, lots of space, and great lakefront access! The puzzle and game collection is also impressive. Would stay here again!"

Other attractions near Lake Issaqueena

Larry W. Abernathy Waterfront Park

8.6/10 (58 reviews)

Larry W. Abernathy Waterfront Park is just one of the places to see in Clemson, so why not enjoy the other things to explore during your travels? Experience the area's theatre scene or attend a football match.

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Littlejohn Coliseum

9.4/10 (141 reviews)

Catch an event at Littlejohn Coliseum during your trip to Clemson. Amble around the area's lakeside or attend a football match.

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Sloan Tennis Center

Catch an event at Sloan Tennis Center during your trip to Clemson. You can attend a football match while in the area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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Clemson Area African American Museum

You can spend time exploring the galleries in Clemson Area African American Museum in Clemson. You can attend a football match while in the area.

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Wyndham Plaza

You can search for that perfect souvenir at Wyndham Plaza during your stay in Seneca. Stroll along the lakeside or attend a sporting event in this family-friendly area.

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World of Energy

You can spend an afternoon browsing the exhibits at World of Energy in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.

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Frequently asked questions

What's the area like around Lake Issaqueena?

Lake Issaqueena is located in Central. You'll find 208 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Lake Issaqueena?

Lakeside Lodge Clemson is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. It's located 3.5 mi (5.6 km) from Lake Issaqueena. Other good choices within 5 miles include Best Western Plus Clemson Hotel & Conference Center and Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!.

How many hotels will I find close to Lake Issaqueena?

Expedia has 208 hotels and other accommodation options a few miles from Lake Issaqueena.

If I need to cancel the hotel reservation for my stay near Lake Issaqueena, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the top deals on offer near Lake Issaqueena.

What can I see and do near Lake Issaqueena?

You'll want to browse the exhibits at Fort Hill and Clemson Area African American Museum. Explore nature at Keowee Reservoir and Larry W. Abernathy Waterfront Park. If you've got some time to explore the area around Lake Issaqueena, you may want to make a stop by Littlejohn Coliseum, Memorial Stadium and Sloan Tennis Center.

Search Hotels Near Lake Issaqueena, Central

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Lake Issaqueena hotels

1. Best Western Plus Clemson Hotel & Conference Center

2. Comfort Inn & Suites Clemson - University Area

3. Fairfield Inn & Suites Seneca Clemson Univ Area

4. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

5. Hampton Inn & Suites Seneca-Clemson Area

6. Holiday Inn Express & Suites Clemson by IHG

7. Inn @ Clemson

8. Best Western Seneca-Clemson

9. The Inn at Patrick Square

10. Quality Inn Seneca US-123

11. Courtyard Marriott Clemson

12. Days Inn by Wyndham Clemson

13. Carolina Camp Cedar

14. Days Inn by Wyndham Seneca / Clemson Area

15. Hampton Inn Clemson-University Area

16. Rodeway Inn & Suites Walhalla

17. The Point At Lake Hartwell

18. Econo Lodge Clemson - University Area

Compare popular hotels close to Lake Issaqueena

Top Lake Issaqueena Hotel Reviews

The Shepherd Hotel Downtown Clemson

Inn @ Clemson

Clemson Barndominium -close to University and lakes

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Wraparound Porch Downtime, Memorial Stadium 5 Mi

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Hampton Inn Clemson-University Area

NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football

Other attractions near Lake Issaqueena

Larry W. Abernathy Waterfront Park

Littlejohn Coliseum

Sloan Tennis Center

Memorial Stadium

Clemson Area African American Museum

Wyndham Plaza

World of Energy

Frequently asked questions