Title: TOP Jeffersonville - Clarksville Spa Hotels for 2026 - Spas in Jeffersonville - Clarksville, IN | Expedia.co.uk [Jeffersonville - Clarksville Travel Guide](https://expedia.co.uk/Jeffersonville-Clarksville.dx6059638)[Hotels in Jeffersonville - Clarksville](https://expedia.co.uk/Jeffersonville-Clarksville-Hotels.d6059638.Travel-Guide-Hotels)[Holiday Rentals in Jeffersonville - Clarksville](https://expedia.co.uk/Jeffersonville-Clarksville-Holiday-Rentals.d6059638.Travel-Guide-HolidayRentals)[Flights to Jeffersonville - Clarksville](https://expedia.co.uk/Cheap-Flights-To-Jeffersonville-Clarksville.d6059638.Travel-Guide-Flights)[Jeffersonville - Clarksville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Jeffersonville-Clarksville.d6059638.Car-Hire-Guide)[Jeffersonville - Clarksville Holidays](https://expedia.co.uk/Jeffersonville-Clarksville.d6059638.Holidays-City-Breaks) ![View of Louisville from the Falls of the Ohio at Golden Hour. #BVSblue](https://images.trvl-media.com/place/3108/df34b2a2-a0fe-4fea-b211-931e06d4c702.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Eric O ![](https://images.trvl-media.com/place/3108/df34b2a2-a0fe-4fea-b211-931e06d4c702.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Jeffersonville - Clarksville Spa Hotels Tonight [14 Jan - 15 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2026-01-14&endDate=2026-01-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [15 Jan - 16 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2026-01-15&endDate=2026-01-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Jeffersonville - Clarksville hotels with a spa ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/506c167d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination [](https://www.expedia.co.uk/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) Elizabeth 8.2/10 Very good (1,004 reviews) "Rooms were spacious and clean. Bathroom spacious and clean. Liked the proximity to the casino" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaime £87 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,000 reviews) "Excellent place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anatole £120 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/e725185b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Non Smoking (East Twr, Waterview, 2 Queens, 1 King) | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/38ee770d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (3,977 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos £118 includes taxes & fees 28 Jan - 29 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,760 reviews) "Beautiful, spacious hotel. Spotless room, kind and helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gizella £146 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eec2d0c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reserve on Main [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) Downtown Louisville 10/10 Exceptional (1 review) "Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) georgios £179 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/95d9177a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/787112cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/94b6bd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/1e2d6baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Park Bed & Breakfast [](https://www.expedia.co.uk/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information) Old Louisville 9.2/10 Wonderful (59 reviews) "Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £109 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/40c412dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Multiple Beds, Pets allowed, Garden View | Living area | 42-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/82066f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/e77d0e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pillow and Paddock B&B [](https://www.expedia.co.uk/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) La Grange 10/10 Exceptional (52 reviews) "Courteous staff and the room was outstanding. It was our second stay at the inn. Everything is first class. We highly recommend it." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fran £284 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29®ionId=6059638&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Jeffersonville - Clarksville Hotel Reviews ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Iconic hotel in the heart of Louisville. Walkable and convenient." [](https://expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "All of the staff was very friendly " [](https://expedia.co.uk/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information) ![Caesars Southern Indiana - A Caesars Rewards Destination](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc_y.jpg) ### Caesars Southern Indiana - A Caesars Rewards Destination 10/10 Excellent "Bra had good selection. plenty of variety for slots and lots of tables available " [](https://expedia.co.uk/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Austin Hotels ](https://www.expedia.co.uk/Austin-Hotels.d75646.Travel-Guide-Hotels) - 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