A large building with a dome and columns, surrounded by trees and a grassy area.

Find Spa Hotels in Jeffersonville - Clarksville, IN

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Jeffersonville - Clarksville Spa Hotels

Tonight
10 Oct - 11 Oct
Tomorrow
11 Oct - 12 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Jeffersonville - Clarksville hotels with a spa

A restaurant with round tables, chairs, chandeliers, and a bar area.
A hot tub with a pool, indoor seating area, and a view of the pool.
A spacious lobby with a geometric chandelier, a reception desk, and a red accent wall.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.

1. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
£66
includes taxes & fees
9 Nov - 10 Nov
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A modern hotel room with a large window, a sofa, a red armchair, and a small table.

2. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
£129
includes taxes & fees
25 Oct - 26 Oct
Galt House Hotel Trademark Collection by Wyndham
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A steam fountain in a brick alleyway.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A modern bathroom with a shower, a sink, and a large mirror.

3. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness centre in city centre Louisville.
£139
includes taxes & fees
8 Nov - 9 Nov
21c Museum Hotel Louisville
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern interior with a fireplace, bookshelves, and seating areas.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

4. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
£226
includes taxes & fees
30 Oct - 31 Oct
Omni Louisville Hotel
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A living room with a sofa, coffee table, and a television mounted on the wall.
A cozy room with a wooden wall, a sofa, and a dining table.
A modern bathroom with a shower, a vanity with a sink, and a toilet. There are wooden shelves and a vase with flowers on the vanity.

5. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cosy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
£276
includes taxes & fees
16 Oct - 17 Oct
Pillow and Paddock B&B
View all properties

Choose what matters most at spa hotels in Jeffersonville - Clarksville

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Jeffersonville - Clarksville Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"The staff was very friendly and acknowledged us at the front desk and while walking through the hotel. Breakfast was cooked to order and hot. Very friendly dining room staff. Bedroom and bathroom were clean and very nicely organized and decorated."
Thomas 2-night trip
Posted 6 hours ago
Galt House Hotel Trademark Collection by Wyndham

Explore a world of travel with Expedia