Title: TOP Jeffersonville - Clarksville Spa Hotels for 2025 - Spas in Jeffersonville - Clarksville, IN | Expedia.co.uk [Jeffersonville - Clarksville Travel Guide](https://expedia.co.uk/Jeffersonville-Clarksville.dx6059638)[Hotels in Jeffersonville - Clarksville](https://expedia.co.uk/Jeffersonville-Clarksville-Hotels.d6059638.Travel-Guide-Hotels)[Holiday Rentals in Jeffersonville - Clarksville](https://expedia.co.uk/Jeffersonville-Clarksville-Holiday-Rentals.d6059638.Travel-Guide-HolidayRentals)[Flights to Jeffersonville - Clarksville](https://expedia.co.uk/Cheap-Flights-To-Jeffersonville-Clarksville.d6059638.Travel-Guide-Flights)[Jeffersonville - Clarksville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Jeffersonville-Clarksville.d6059638.Car-Hire-Guide)[Jeffersonville - Clarksville Holidays](https://expedia.co.uk/Jeffersonville-Clarksville.d6059638.Holidays-City-Breaks) ![View of Louisville from the Falls of the Ohio at Golden Hour. #BVSblue](https://images.trvl-media.com/place/3108/df34b2a2-a0fe-4fea-b211-931e06d4c702.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Eric O # Find Spa Hotels in Jeffersonville - Clarksville, IN - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Jeffersonville - Clarksville Spa Hotels Tonight [30 Nov - 1 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-11-30&endDate=2025-12-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Dec - 2 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-12-01&endDate=2025-12-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Jeffersonville - Clarksville Spa Hotels ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/a36c57b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination Elizabeth 8.2/10 Very good (1020) "Easy parking, Very friendly/helpful staff, easy check in/out, Nice casino, Good food options" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie £75 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham Downtown Louisville 9.0/10 Wonderful (3821) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tia £83 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/a0c5fbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/97b4a308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/1f90bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reserve on Main Downtown Louisville 10/10 Exceptional (1) "Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) georgios £153 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.2/10 Wonderful (1005) " Loved our stay, would definitely plan to come back if we are ever in the area again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica £163 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/95d9177a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/437bf0ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/1e2d6baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/c7cb5a92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Park Bed & Breakfast Old Louisville 9.4/10 Exceptional (56) "The room was beautiful, breakfast was delicious and the park across the street was lovely. I especially enjoyed having coffee on the back veranda." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cher £106 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information) ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/w5757h3840x3y0-b0a2f211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e108d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel Downtown Louisville 9.2/10 Wonderful (1704) "Wonderful property and staff. Would love to stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hanna £177 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/9cc68008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Apartment, 1 King Bed with Sofa bed, Kitchenette, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/46f16aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/f227b8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Multiple Beds, Kitchenette, Garden View | Living area | 42-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pillow and Paddock B&B La Grange 10/10 Exceptional (51) "This has been our second time staying here and we will continue to come back. Beautiful home, amazing breakfasts, and wonderful hosts, not much else we could ask for. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel £250 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-14&endDate=2025-12-15®ionId=6059638&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6059638) ## Top Jeffersonville - Clarksville Hotel Reviews ![Courtyard by Marriott Louisville Airport](https://images.trvl-media.com/lodging/1000000/880000/874400/874388/9148c40a_y.jpg) ### Courtyard by Marriott Louisville Airport 10/10 Excellent "Staff was really nice and informative " [](https://expedia.co.uk/Louisville-Hotels-Courtyard-By-Marriott-Louisville-Airport.h874388.Hotel-Information) ![Drury Inn & Suites Louisville East](https://images.trvl-media.com/lodging/1000000/800000/793000/792962/d2587f53_y.jpg) ### Drury Inn & Suites Louisville East 10/10 Excellent "all great" [](https://expedia.co.uk/Louisville-Hotels-Drury-Inn-Suites-Louisville-East.h792962.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "great staff" [](https://expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ## Explore a world of travel with Expedia - 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[Madison Holidays](https://www.expedia.co.uk/Madison.d6059636.Holidays-City-Breaks) - [Salem Holidays](https://www.expedia.co.uk/Salem.d177544.Holidays-City-Breaks) - [Scottsburg Holidays](https://www.expedia.co.uk/Scottsburg.d6725.Holidays-City-Breaks) - [Car hire in Budget Tillypark 10](https://www.expedia.co.uk/Budget-at-Tillypark-10-Nuernberg-DEU.v7184.Car-Rental-Guide-Location) - [Car hire Jeffersonville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Jeffersonville.d8031.Car-Hire-Guide) - [Car hire Sellersburg](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Sellersburg.d6542.Car-Hire-Guide) - [National Car Rental Rental Cars in New Amsterdam](https://www.expedia.co.uk/National-Car-Rental-Car-Rentals-In-New-Amsterdam.d553248634998737085-c42.Car-Rental-Guide-Suppliers) - [Austin Holiday Rentals](https://www.expedia.co.uk/Austin-Holiday-Rentals.d75646.Travel-Guide-HolidayRentals) - [Madison Holiday Rentals](https://www.expedia.co.uk/Madison-Holiday-Rentals.d6059636.Travel-Guide-HolidayRentals) - [Things to do in Jeffersonville](https://www.expedia.co.uk/Things-To-Do-In-Jeffersonville.d8031.Travel-Guide-Activities) - [Book Spa Hotels in Jeffersonville - Clarksville on Expedia.com](https://www.expedia.com/Jeffersonville-Clarksville-Hotels-Spa-Hotel.0-0-d6059638-tSpaHotel.Travel-Guide-Filter-Hotels)