The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis - 2026 Updated Prices

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Our top choices for James S. McDonnell Prologue Room hotels

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

1. Wingate by Wyndham St. Louis Airport

1.6 mi from James S. McDonnell Prologue Room

Mary

£83

includes taxes & fees

28 Sept - 29 Sept

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

2. Pear Tree Inn St. Louis Airport

1.6 mi from James S. McDonnell Prologue Room

Monica

£80

includes taxes & fees

4 Oct - 5 Oct

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A pool area with two hot tubs, seating, and a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

3. Drury Inn & Suites St. Louis Airport

1.3 mi from James S. McDonnell Prologue Room

Hope

£102

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

4. Hyatt Select St. Louis Airport

1.2 mi from James S. McDonnell Prologue Room

Maxine

£102

includes taxes & fees

8 Oct - 9 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A snack vending machine with various snack options.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

5. Hampton Inn By Hilton St Louis Airport

1.2 mi from James S. McDonnell Prologue Room

Leia

£116

includes taxes & fees

8 Oct - 9 Oct

A buffet with fruits, pastries, and beverages.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

6. Renaissance St. Louis Airport Hotel

Berkeley, 1.2 mi from James S. McDonnell Prologue Room

Anthony

£104

includes taxes & fees

4 Oct - 5 Oct

A breakfast buffet with labeled sections for fruit and cereal.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A Holiday Inn Express & Suites building with a covered entrance, a truck with the hotel branding, and a clear sky.

7. Holiday Inn Express & Suites St Louis Airport by IHG

1.2 mi from James S. McDonnell Prologue Room

Keneace

£113

includes taxes & fees

25 Oct - 26 Oct

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A modern lobby with seating areas, a reception desk, and a bar area.

8. Marriott St. Louis Airport

1.5 mi from James S. McDonnell Prologue Room

Chris

£134

includes taxes & fees

2 Oct - 3 Oct

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

9. DoubleTree by Hilton St. Louis Airport

1.3 mi from James S. McDonnell Prologue Room

Samone

£101

includes taxes & fees

2 Oct - 3 Oct

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

10. Hilton St. Louis Airport

1.2 mi from James S. McDonnell Prologue Room

raymond

£123

includes taxes & fees

3 Oct - 4 Oct

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

11. Quality Inn Florissant - St Louis

1.9 mi from James S. McDonnell Prologue Room

Sharonda

£60

includes taxes & fees

18 Oct - 19 Oct

A parking lot with multiple cars, a building with a green and beige facade, and a sign for Home Towne Studios.

A hotel entrance with a covered waiting area, a parking lot, and a building with multiple windows and a green exterior.

A compact kitchenette with a sink, stove, microwave, and a white refrigerator.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

1.8 mi from James S. McDonnell Prologue Room

Kimberly

£65

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bed, bedside tables, a heater, and a view of the city.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A multi-story brick building with a central entrance, parking lot, and designated handicapped parking spaces.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

13. Welcome Suites Hazelwood

1.9 mi from James S. McDonnell Prologue Room

Arutyun

£69

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A spacious lobby with a patterned tile floor, a staircase, and seating areas.

14. Quality Inn Saint Louis Airport

1.2 mi from James S. McDonnell Prologue Room

Gordon

£55

includes taxes & fees

4 Oct - 5 Oct

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

A gym with treadmills, stationary bikes, and a weight machine.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

15. Drury Plaza Hotel St. Louis St. Charles

8 mi from James S. McDonnell Prologue Room

Robert

£119

includes taxes & fees

12 Oct - 13 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

A spa bath with a sign indicating a capacity of 8 persons.

16. Drury Plaza Hotel St. Louis Brentwood

8.4 mi from James S. McDonnell Prologue Room

Janell

£122

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A snack and treat display with various products, including chips and beverages, in a store setting.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

17. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 9 mi from James S. McDonnell Prologue Room

Jennifer

£123

includes taxes & fees

4 Oct - 5 Oct

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

A hotel room with two beds, a desk, and a chair.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

18. The Knight Center at Washington University

7.1 mi from James S. McDonnell Prologue Room

Kenney

£147

includes taxes & fees

28 Sept - 29 Sept

An outdoor patio with a fire pit, seating, and a building in the background.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

19. Courtyard by Marriott St. Louis Brentwood

8.4 mi from James S. McDonnell Prologue Room

Aaron

£105

includes taxes & fees

4 Oct - 5 Oct

A rooftop terrace with a fire feature, outdoor seating, and a city view.

A modern lounge area with a fireplace, a flat-screen TV, and a dining area with chairs and tables.

A modern bar area with round tables and blue chairs, a wooden bar counter, and a television mounted on the wall.

A hotel with a modern brick facade, large windows, and a well-lit entrance.

20. Residence Inn By Marriott St. Louis Clayton

Clayton, 6.8 mi from James S. McDonnell Prologue Room

Donna

£154

includes taxes & fees

2 Oct - 3 Oct

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,718 reviews	View
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,268 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,425 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,005 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 227 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Nice clean stay."

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"Very nice staff"

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Excellent stay"

Wingate by Wyndham St. Louis Airport

10/10 Excellent

"Perfect spot for flying out the next morning"

Hyatt Select St. Louis Airport

10/10 Excellent

"The checkin was fast and efficient. The room was clean. The beds were comfortable and clean. The hotel is in an excellent location to the airport and car rental. The shuttle schedule is great for early flights."

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Staff was great! Would come back to stay."

Holiday Inn Express & Suites St Louis Airport by IHG

10/10 Excellent

"Every thing was perfect. The staff was VERY attentive, rooms were very comfortable, the bed was the most comfortable and the breakfast was more than enough. Absolutely would stay here again."

Hilton St. Louis Airport

10/10 Excellent

"Service"

Delightful 2-bedroom house with AC in Berkeley Iconixx Getaway STL

10/10 Excellent

"Great host! She made it very easy for me to check in and check out. Quiet neighborhood, and comfortable home! "

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Blacks in Flight Mural

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you take a trip to Payne-Gentry Historical House. Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine during your travels in Florissant. Experience the great live music and acclaimed theatre scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time studying the exhibits at St. Louis Car Museum during your travels in Overland. Experience the acclaimed theatre scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time exploring the galleries in St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theatre scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your stay in St. Louis. Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I be able to find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodation options a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best options available near James S. McDonnell Prologue Room.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're out exploring.

Search Hotels Near James S. McDonnell Prologue Room, St. Louis

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Wingate by Wyndham St. Louis Airport

2. Pear Tree Inn St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Hyatt Select St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Renaissance St. Louis Airport Hotel

7. Holiday Inn Express & Suites St Louis Airport by IHG

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Hampton Inn & Suites St. Louis at Forest Park

18. The Knight Center at Washington University

19. Courtyard by Marriott St. Louis Brentwood

20. Residence Inn By Marriott St. Louis Clayton

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Drury Inn & Suites St. Louis Airport

Hampton Inn By Hilton St Louis Airport

Pear Tree Inn St. Louis Airport

Wingate by Wyndham St. Louis Airport

Hyatt Select St. Louis Airport

Renaissance St. Louis Airport Hotel

Holiday Inn Express & Suites St Louis Airport by IHG

Hilton St. Louis Airport

Delightful 2-bedroom house with AC in Berkeley Iconixx Getaway STL

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions