The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis - 2026 Updated Prices

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

1. Pear Tree Inn St. Louis Airport

1.6 mi from James S. McDonnell Prologue Room

Murphy

£80

includes taxes & fees

4 Oct - 5 Oct

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A pool area with two hot tubs, seating, and a view of the outdoors.

2. Drury Inn & Suites St. Louis Airport

1.3 mi from James S. McDonnell Prologue Room

Lakeshia

£102

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A modern lobby with blue seating, a reception desk, and large windows.

3. Hyatt Select St. Louis Airport

1.2 mi from James S. McDonnell Prologue Room

Maxine

£102

includes taxes & fees

8 Oct - 9 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

A snack vending machine with various snack options.

4. Hampton Inn By Hilton St Louis Airport

1.2 mi from James S. McDonnell Prologue Room

Leia

£116

includes taxes & fees

8 Oct - 9 Oct

A buffet with fruits, pastries, and beverages.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

5. Renaissance St. Louis Airport Hotel

Berkeley, 1.2 mi from James S. McDonnell Prologue Room

Anthony

£104

includes taxes & fees

4 Oct - 5 Oct

A breakfast buffet with labeled sections for fruit and cereal.

A gym with treadmills, stationary bikes, and a mirrored wall.

A Holiday Inn Express & Suites building with a covered entrance, a truck with the hotel branding, and a clear sky.

A coffee station with two coffee machines and a variety of coffee pods and cups.

6. Holiday Inn Express & Suites St Louis Airport by IHG

1.2 mi from James S. McDonnell Prologue Room

Keneace

£113

includes taxes & fees

25 Oct - 26 Oct

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

7. Marriott St. Louis Airport

1.5 mi from James S. McDonnell Prologue Room

Chris

£134

includes taxes & fees

3 Oct - 4 Oct

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

8. DoubleTree by Hilton St. Louis Airport

1.3 mi from James S. McDonnell Prologue Room

Samone

£101

includes taxes & fees

2 Oct - 3 Oct

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

9. Hilton St. Louis Airport

1.2 mi from James S. McDonnell Prologue Room

raymond

£123

includes taxes & fees

3 Oct - 4 Oct

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

10. Quality Inn Florissant - St Louis

1.9 mi from James S. McDonnell Prologue Room

Sharonda

£60

includes taxes & fees

19 Oct - 20 Oct

A parking lot with multiple cars, a building with a green and beige facade, and a sign for Home Towne Studios.

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A compact kitchenette with a sink, stove, microwave, and a white refrigerator.

11. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

1.8 mi from James S. McDonnell Prologue Room

Kimberly

£65

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bed, bedside tables, a heater, and a view of the city.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

A multi-story brick building with a central entrance, parking lot, and designated handicapped parking spaces.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

12. Welcome Suites Hazelwood

1.9 mi from James S. McDonnell Prologue Room

Arutyun

£69

includes taxes & fees

29 Sept - 30 Sept

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

13. Quality Inn Saint Louis Airport

1.2 mi from James S. McDonnell Prologue Room

Gordon

£55

includes taxes & fees

4 Oct - 5 Oct

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

A gym with treadmills, stationary bikes, and a weight machine.

14. Drury Plaza Hotel St. Louis St. Charles

8 mi from James S. McDonnell Prologue Room

Robert

£119

includes taxes & fees

12 Oct - 13 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

15. Drury Plaza Hotel St. Louis Brentwood

8.4 mi from James S. McDonnell Prologue Room

Janell

£122

includes taxes & fees

4 Oct - 5 Oct

A brick building with a sign reading "Country Inn & Suites."

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

16. Country Inn & Suites by Radisson, St. Charles Historic District

7.7 mi from James S. McDonnell Prologue Room

Roseanna

£122

includes taxes & fees

12 Oct - 13 Oct

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

17. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 9 mi from James S. McDonnell Prologue Room

Jennifer

£123

includes taxes & fees

4 Oct - 5 Oct

A courtyard with outdoor seating, a central fountain, and a view of a tower.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

18. The Knight Center at Washington University

7.1 mi from James S. McDonnell Prologue Room

Kenney

£147

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a fire pit, seating, and a building in the background.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

19. Courtyard by Marriott St. Louis Brentwood

8.4 mi from James S. McDonnell Prologue Room

Aaron

£105

includes taxes & fees

4 Oct - 5 Oct

A rooftop restaurant with round tables, chairs, and a view of the city.

A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.

A modern lobby with a staircase, seating area, and wall-mounted artwork.

A modern lobby with a staircase, seating area, and an exit sign.

20. Moonrise Hotel

7 mi from James S. McDonnell Prologue Room

Nicole

£119

includes taxes & fees

11 Oct - 12 Oct

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,270 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,427 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,007 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 227 reviews	View
Renaissance St. Louis Airport Hotel	8.4 Very good 1,188 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"Very nice staff"

Wingate by Wyndham St. Louis Airport

10/10 Excellent

"Perfect spot for flying out the next morning"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Staff was great! Would come back to stay."

Holiday Inn Express & Suites St Louis Airport by IHG

10/10 Excellent

"Every thing was perfect. The staff was VERY attentive, rooms were very comfortable, the bed was the most comfortable and the breakfast was more than enough. Absolutely would stay here again."

Hilton St. Louis Airport

10/10 Excellent

"Service"

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I be able to find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodation options a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best options available near James S. McDonnell Prologue Room.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're out exploring.

Search Hotels Near James S. McDonnell Prologue Room, St. Louis

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Drury Inn & Suites St. Louis Airport

3. Hyatt Select St. Louis Airport

4. Hampton Inn By Hilton St Louis Airport

5. Renaissance St. Louis Airport Hotel

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Marriott St. Louis Airport

8. DoubleTree by Hilton St. Louis Airport

9. Hilton St. Louis Airport

10. Quality Inn Florissant - St Louis

11. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

12. Welcome Suites Hazelwood

13. Quality Inn Saint Louis Airport

14. Drury Plaza Hotel St. Louis St. Charles

15. Drury Plaza Hotel St. Louis Brentwood

16. Country Inn & Suites by Radisson, St. Charles Historic District

17. Hampton Inn & Suites St. Louis at Forest Park

18. The Knight Center at Washington University

19. Courtyard by Marriott St. Louis Brentwood

20. Moonrise Hotel

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Hampton Inn By Hilton St Louis Airport

Wingate by Wyndham St. Louis Airport

Renaissance St. Louis Airport Hotel

Holiday Inn Express & Suites St Louis Airport by IHG

Hilton St. Louis Airport

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions