Isle of Palms South Holidays

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Your Isle of Palms South Holiday

Your next big journey is just around the corner with a holiday package to Isle of Palms South. Entertainment, relaxation and nonstop good times — you're bound to find it in this neighbourhood. Begin your trip to Isle of Palms South by visiting nearby attractions such as Jacksonville Beach Pier, Adventure Landing and Oceanfront Park. Whatever your dream Isle of Palms South holiday may look like, you can make it a reality with Expedia.

Price found within the past 48 hours. Click for updated prices.
  • Desk, laptop workspace, blackout curtains, iron/ironing board
    Aug 12 - Aug 19

    Airport Motor Inn + Flight

    Northside
    7 nights
    2.5 star property
    7.8/10 - Good (210 reviews)
    "If you like ghetto living then this would be the place. My wife and daughter were feared and felt very uncomfortable. The smell should have been a red flag, except you cant smell it online. No shuttle to airport despite being only 1.5 miles from airport. On a scale of 1-10, they owe me points."
    Reviewed May 18, 2026
    Return • London (LHR) - Orlando (MCO)
    LHR - MCO • 1 stop MCO - LHR • 1 stop
    £788
    £706
    per traveller
    found 1 day ago
    Airport Motor Inn
  • Aug 12 - Aug 19

    Quality Inn Jacksonville South + Flight

    Southside
    7 nights
    2.5 star property
    6.8/10 - (925 reviews)
    "Friendly staff. Quick check-in. Clean room. Fare rate for what/where it is. Could be a little sketchy outside at times but no one bothers u. Just mind ur business, that's all. Lol my only slight issue would be the shower curtain rod was broken so had to be creative with holding the shower curtain up on both ends of the rod, but that's nothing... No reason to"
    Reviewed April 6, 2026
    Return • London (LHR) - Orlando (MCO)
    LHR - MCO • 1 stop MCO - LHR • 1 stop
    £771
    £741
    per traveller
    found 1 day ago
    Quality Inn Jacksonville South
  • Lobby
    Aug 12 - Aug 19

    Wyndham Garden Jacksonville + Flight

    Southside
    7 nights
    3.0 star property
    8.0/10 - Very good (1,879 reviews)
    "This was our 3rd stay at this hotel. Clean. Basic hotel. People slamming doors on our floor wasn't ideal. Outside could stand to be cleaned up. Otherwise, we would stay here again."
    Reviewed May 19, 2026
    Return • London (LHR) - Orlando (MCO)
    LHR - MCO • 1 stop MCO - LHR • 1 stop
    £755
    £755
    per traveller
    found 1 day ago
    Wyndham Garden Jacksonville

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms South
Fernandina Beach, Florida, USA Historic Downtown 1958

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Find hotels in Amelia City

Top hotels in Isle of Palms South

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
The price is £159 per night from 26 May to 27 May
£159
26 May - 27 May
includes taxes & fees
9/10 Wonderful! (3,968 reviews)
"Very close to pier. Lovely motel and staff. Will stay again"

Reviewed on 21 May 2026

Margaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is £154 per night from 25 May to 26 May
£154
25 May - 26 May
includes taxes & fees
9/10 Wonderful! (1,605 reviews)
"The room was adequate. Could really use an update/refresh. Really not a lot to see and do, or places to eat once you get to the property."

Reviewed on 19 May 2026

Hyatt Regency Jacksonville
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is £67 per night from 4 Jun to 5 Jun
£67
4 Jun - 5 Jun
includes taxes & fees
8/10 Very Good! (1,879 reviews)
"This was our 3rd stay at this hotel. Clean. Basic hotel. People slamming doors on our floor wasn't ideal. Outside could stand to be cleaned up. Otherwise, we would stay here again."

Reviewed on 19 May 2026

Wyndham Garden Jacksonville
See all 3,120 properties in Isle of Palms South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
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Family Friendly Holidays

Frequently asked questions

How much does an Isle of Palms South travel package cost?
Custom build your Isle of Palms South package from as little as . Pick from any combination of rental cars, flights and hotels to put together the escape you've been dreaming about. Don't forget to add on some activities and experiences!
If I'm not able to travel, can I cancel my Isle of Palms South travel package?
Whether it's your flight or hotel, you can cancel or alter it. Locked in your Isle of Palms South travel package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may incur a charge from your hotel, airline or car rental company. For more information, look up our Customer Service Portal. We're here to help you each step of the way.
How do I get a cheap travel package to Isle of Palms South?
Our Isle of Palms South travel packages mean plenty of savings for the savvy globetrotter. For the best deal, simply combine your hotel, flights and extras (such as activities) into an affordable package. But bargain prices are only the start of your next epic adventure. When you book with Expedia, and you'll have over 550 air carriers and 1,000,000 properties across the globe to choose from. No matter your budget, there's a travel package here just for you.
Does Expedia offer Book Now, Pay Later Isle of Palms South holidays?
We sure do. Expedia has joined forces with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply select the payment plan that suits best during the checkout process and take the stress out of budgeting for your trip. Remember to bundle your flights, accommodation and car hire with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's monthly instalment plans. If paying just a small amount each month works for you, choose this option at checkout.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Then select this Book Now, Pay Later option from Klarna.
  • Low deposit holidays: When you stumble on an unbeatable deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you secure your getaway.

Where should I stay in Isle of Palms South?
A getaway to Isle of Palms South isn't complete without paying a visit to Adventure Landing, Jacksonville Beach Pier and Oceanfront Park. Stay near these sights and make sightseeing a breeze.
What are the top hotels in Isle of Palms South?
Get your escape off to a fantastic start by booking a room at Four Points by Sheraton Jacksonville Beachfront. It's one of most popular hotels in Isle of Palms South. Another option is Hampton Inn Jacksonville Beach/Oceanfront.
How far in advance should I book my Isle of Palms South holiday?
Travellers are usually able to look up international airfares on Expedia up to a year in advance of departure. Booking last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket just weeks before your journey.
What does an Expedia Isle of Palms South travel package include?
Choose from any combination of hotels, flights and rental cars. Once you've made your booking, you can add the fun stuff like experiences and tours. Want to pick your airfare class? That's also possible. The choice is all yours when it comes to arranging your perfect Isle of Palms South escape.
What should I know before booking an Isle of Palms South travel package?
An Expedia travel package can be customized for your circumstances and is an easy way to make your money go further. What you include is your call. Rental cars, hotels and flights — mix and match whatever combination suits your style.
Can I choose my airline with an Isle of Palms South Expedia travel package?
Yes, you sure can. Expedia has access to more than 550 partner airlines worldwide, so choose the carrier that best suits your travel needs.

Popular places to visit

Mayport Naval Station

Mayport Naval Station

Mayport Naval Station is just one of the places to see in Jacksonville, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's beautiful beaches or experience its acclaimed theatre scene.

Mayport Naval Station
EverBank Stadium

EverBank Stadium

5/5(1 review)

Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.

EverBank Stadium
Golf Course

TPC Sawgrass

4.5/5(5 reviews)

Enjoy a round of golf in Ponte Vedra Beach at TPC Sawgrass. Stroll along the area's seaside or experience its acclaimed theatre scene.

TPC Sawgrass

Things to do

CraigCat Boat Tour from Fernandina Beach

CraigCat Boat Tour from Fernandina Beach

£106
per adult
98% of travellers recommend
CraigCat Boat Tour from Fernandina Beach
St. Marys Murder, Mayhem, and Martinis Walking Tour

St. Marys Murder, Mayhem, and Martinis Walking Tour

£18
per adult
St. Marys Murder, Mayhem, and Martinis Walking Tour
Specters of the Spanish Moss: Jacksonville Ghost Tour

Specters of the Spanish Moss: Jacksonville Ghost Tour

£19
per adult
100% of travellers recommend
Specters of the Spanish Moss: Jacksonville Ghost Tour
See all activities in Jacksonville

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.