Title: Full-size Isla Popa Car Hire | Expedia.co.uk ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Full-size Car Hire Companies in Isla Popa [Become a member for free](https://expedia.co.uk/member-price?rfrr=TG.CM) and get more than just a booking discount. Members also earn points towards their next trip. Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more. Enjoy maximum flexibility with penalty-free cancellation on most car rentals. ## Find Cheap Full-size Car Deals for Isla Popa \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car hire in Isla Popa [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Isla%20Popa,%20Bocas%20del%20Toro%20Province,%20Panama&dpln=6144989&date1=22/09/2025&date2=24/09/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22fullsize%22]) ## Fullsize Car Hire Information | Car type: | Fullsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | - Experience new places with Expedia ### Find Popular Airports close to Isla Popa - [Car hire at Tocumen Intl. Airport (PTY)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Tocumen-Intl.d5854288.Car-Hire-Guide) ### Find Other Car Classes in Isla Popa - [Mini car hire in Isla Popa](https://expedia.co.uk/Mini-Car-Rentals-In-Isla-Popa.d6144989-tMini.Car-Rental-Guide-Class) - [Economy car hire in Isla Popa](https://expedia.co.uk/Economy-Car-Rentals-In-Isla-Popa.d6144989-tEconomy.Car-Rental-Guide-Class) - [Compact car hire in Isla Popa](https://expedia.co.uk/Compact-Car-Rentals-In-Isla-Popa.d6144989-tCompact.Car-Rental-Guide-Class) - [Midsize car hire in Isla Popa](https://expedia.co.uk/Midsize-Car-Rentals-In-Isla-Popa.d6144989-tMidsize.Car-Rental-Guide-Class) - [Standard car hire in Isla Popa](https://expedia.co.uk/Standard-Car-Rentals-In-Isla-Popa.d6144989-tStandard.Car-Rental-Guide-Class) - [Premium car hire in Isla Popa](https://expedia.co.uk/Premium-Car-Rentals-In-Isla-Popa.d6144989-tPremium.Car-Rental-Guide-Class) - [Luxury car hire in Isla Popa](https://expedia.co.uk/Luxury-Car-Rentals-In-Isla-Popa.d6144989-tLuxury.Car-Rental-Guide-Class) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)