Title: Full-size Barro Colorado Island Car Hire | Expedia.co.uk ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Full-size Car Hire Companies in Barro Colorado Island [Become a member for free](https://expedia.co.uk/member-price?rfrr=TG.CM) and get more than just a booking discount. Members also earn points towards their next trip. Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more. Enjoy maximum flexibility with penalty-free cancellation on most car rentals. ## Find Cheap Full-size Car Deals for Barro Colorado Island \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car hire in Barro Colorado Island [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Barro%20Colorado%20Island,%20Panam%C3%A1%20Oeste%20Province,%20Panama&dpln=6078515&date1=23/09/2025&date2=25/09/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22fullsize%22]) ## Fullsize Car Hire Information | Car type: | Fullsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | - Experience new places with Expedia ### Find Popular Airports close to Barro Colorado Island - [Car hire at Tocumen Intl. Airport (PTY)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Tocumen-Intl.d5854288.Car-Hire-Guide) - [Car hire at Panama Pacifico Intl. Airport (BLB)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-Pacifico-Intl.d553248633849093600.Car-Hire-Guide) ### Find Other Car Classes in Barro Colorado Island - [Mini car hire in Barro Colorado Island](https://expedia.co.uk/Mini-Car-Rentals-In-Barro-Colorado-Island.d6078515-tMini.Car-Rental-Guide-Class) - [Economy car hire in Barro Colorado Island](https://expedia.co.uk/Economy-Car-Rentals-In-Barro-Colorado-Island.d6078515-tEconomy.Car-Rental-Guide-Class) - [Compact car hire in Barro Colorado Island](https://expedia.co.uk/Compact-Car-Rentals-In-Barro-Colorado-Island.d6078515-tCompact.Car-Rental-Guide-Class) - [Midsize car hire in Barro Colorado Island](https://expedia.co.uk/Midsize-Car-Rentals-In-Barro-Colorado-Island.d6078515-tMidsize.Car-Rental-Guide-Class) - [Standard car hire in Barro Colorado Island](https://expedia.co.uk/Standard-Car-Rentals-In-Barro-Colorado-Island.d6078515-tStandard.Car-Rental-Guide-Class) - [Premium car hire in Barro Colorado Island](https://expedia.co.uk/Premium-Car-Rentals-In-Barro-Colorado-Island.d6078515-tPremium.Car-Rental-Guide-Class) - [Luxury car hire in Barro Colorado Island](https://expedia.co.uk/Luxury-Car-Rentals-In-Barro-Colorado-Island.d6078515-tLuxury.Car-Rental-Guide-Class) - [Convertible car hire in Barro Colorado Island](https://expedia.co.uk/Convertible-Car-Rentals-In-Barro-Colorado-Island.d6078515-tConvertible.Car-Rental-Guide-Class) - [Minivan car hire in Barro Colorado Island](https://expedia.co.uk/Minivan-Car-Rentals-In-Barro-Colorado-Island.d6078515-tMinivan.Car-Rental-Guide-Class) - [Van car hire in Barro Colorado Island](https://expedia.co.uk/Van-Car-Rentals-In-Barro-Colorado-Island.d6078515-tVan.Car-Rental-Guide-Class) - [SUV car hire in Barro Colorado Island](https://expedia.co.uk/SUV-Car-Rentals-In-Barro-Colorado-Island.d6078515-tSUV.Car-Rental-Guide-Class) - [Pickup car hire in Barro Colorado Island](https://expedia.co.uk/Pickup-Car-Rentals-In-Barro-Colorado-Island.d6078515-tPickup.Car-Rental-Guide-Class) - [Sportscar car hire in Barro Colorado Island](https://expedia.co.uk/Sportscar-Car-Rentals-In-Barro-Colorado-Island.d6078515-tSportscar.Car-Rental-Guide-Class) ### Expedia's Latest Trends Hotels - 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