Title: South America Safari Hotels, : South America Hotel Guide | Expedia.co.uk [South America Travel Guide](https://expedia.co.uk/South-America.dx6023117)[South America Hotels](https://expedia.co.uk/Destinations-In-South-America.d6023117.Hotel-Destinations)[Holiday Rentals in South America](https://expedia.co.uk/Destinations-In-South-America.d6023117.Holiday-Rental-Destinations)[South America Flights](https://expedia.co.uk/Destinations-In-South-America.d6023117.Flight-Destinations)[South America Car Hire](https://expedia.co.uk/Destinations-In-South-America.d6023117.Car-Hire-Destinations)[South America Holidays](https://expedia.co.uk/South-America.d6023117.Holidays-City-Breaks) ![Cusco featuring a ruin, heritage architecture and a house](https://images.trvl-media.com/place/941/8118e1a4-6ad8-49e0-b1b9-dbc505b8c6d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Safari Hotels in South America - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South America Safari Hotels Tonight [25 Dec - 26 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Dec - 27 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South America hotels with on-site safari ![Standard Single Room | Water view](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/c138cc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/9eb5534e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/7188dc19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/f5261ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazon Tupana Jungle Lodge [](https://www.expedia.co.uk/Careiro-Hotels-Amazon-Tupana-Jungle-Lodge.h4478459.Hotel-Information) Careiro 9.4/10 Exceptional (18) "I like this hotel a lot I had fun and met a lot of new and friendly people including the staff. All staff was very friendly and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldo [](https://www.expedia.co.uk/Careiro-Hotels-Amazon-Tupana-Jungle-Lodge.h4478459.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/ae54fce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/c95869d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/a9c65e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/97191226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tulipanes Apart de Mar [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Los-Tulipanes-Apart-De-Mar.h14992440.Hotel-Information) Puerto Madryn 9.4/10 Exceptional (8) "Very helpful staff, cozy room, easy walk to beach and restaurants. Breakfast good but selection limited to beads,fruit, juice, kefir, and cereal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Los-Tulipanes-Apart-De-Mar.h14992440.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/e77418ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shared kitchen](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/c5c22c2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/420af2a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/7fe94b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Pueblo Hostel [](https://www.expedia.co.uk/Mendoza-Hotels-Casa-Pueblo-Hostel.h6116802.Hotel-Information) Mendoza 8.0/10 Very good (11) "Great owners! Spent two days in a family atmosphere. Fortaleza is the champion ;)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Mendoza-Hotels-Casa-Pueblo-Hostel.h6116802.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/2dd0bea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1076x0y0-b04af008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1076x0y0-99ca0e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1075x0y0-ee802024.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Curassow Amazon Lodge [](https://www.expedia.co.uk/Fernando-Lores-Hotels-Curassow-Amazon-Lodge.h14882964.Hotel-Information) Fernando Lores 10/10 Exceptional (1) "I am a biologist and I loved the experience at this lodge. The rooms were comfortable with quality sheets and towels changed daily. The food is excellent and prepared from local jungle resources. The guide spoke good English and was very knowledgeable about the local flora and fauna of which we saw lots. We were picked up at the airport and dropped off there afterwards. This company under Leon is very well organised. The lodge is located 3 hours by boat from Iquitos and has no internet and... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Elenab [](https://www.expedia.co.uk/Fernando-Lores-Hotels-Curassow-Amazon-Lodge.h14882964.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/d5d9289c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/04bd526c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/02dece49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/b0d3aef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Millaray [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Millaray.h5426745.Hotel-Information) Providencia 7.8/10 Good (15) "Reserva via telefonica y cuando llegue no estaba mi cupo ni tampoco se esmeraron en buscar solucion, quede sin hospedaje hasta buscar un nuevo hotel. Pesimo servicio." ![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg) andres [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Millaray.h5426745.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/138be8c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Regional cuisine ](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/b248044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Sea View | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/8d2ec907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Regional cuisine ](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/835e622c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Isamar Galapagos Beachfront [](https://www.expedia.co.uk/Puerto-Villamil-Hotels-Isamar-Hotel.h16642518.Hotel-Information) Puerto Villamil 9.0/10 Wonderful (60) "Relaxing room facing a deck with immediate access to the beach. Beach is clean and nice view. Helpful staff and free coffee always available." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suming [](https://www.expedia.co.uk/Puerto-Villamil-Hotels-Isamar-Hotel.h16642518.Hotel-Information) ![Standard Quadruple Room | Premium bedding, pillow-top beds, blackout curtains, rollaway beds](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/7859028f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/fff9a37c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/0f500513.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/b256fdc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nuevo Hotel Misiones [](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Nuevo-Hotel-Misiones.h9404761.Hotel-Information) Puerto Iguazú 6.6/10 (49) "Foi muito bom, otima localizacao" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) ana carolina [](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Nuevo-Hotel-Misiones.h9404761.Hotel-Information) ![Free continental breakfast ](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/56bcd02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/3c2b22ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Ocean View | Premium bedding, minibar, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/6c0094e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/dd1ed17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### RAYENTRAY OCEANO [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Oceano-Patagonia-Wild-Coast-Residence.h18346042.Hotel-Information) Puerto Pirámides 8.4/10 Very good (70) "Staff was helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas £112 27 Dec - 28 Dec [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Oceano-Patagonia-Wild-Coast-Residence.h18346042.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=6023117&adults=2&recreation_group_explore=safari_on_site&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Safari-Hotel.0-0-d6023117-tsafarihotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Safari-Hotel.0-0-d6023117-tsafarihotel.Hotel-Filter-Destinations) ## Top South America Hotel Reviews ![Almacruz Hotel y Centro de Convenciones](https://images.trvl-media.com/lodging/1000000/10000/1500/1496/b4c00de4_y.jpg) ### Almacruz Hotel y Centro de Convenciones 10/10 Excellent "The rooms were clean and the staff were very nice and helpful. The buffet breakfast was amazing and coffee was strong! Best of all, the location is central in downtown, walking distance to many landmarks. :)" [](https://expedia.co.uk/Santiago-Hotels-Almacruz-Hotel-Y-Centro-De-Convenciones.h1496.Hotel-Information) ![Regal Pacific Buenos Aires](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246568/a11bbed3_y.jpg) ### Regal Pacific Buenos Aires 10/10 Excellent "Very good" [](https://expedia.co.uk/Buenos-Aires-Hotels-Regal-Pacific-Buenos-Aires.h1246568.Hotel-Information) ![Melia Paulista](https://images.trvl-media.com/lodging/2000000/1070000/1062900/1062869/a90ff2a9_y.jpg) ### Melia Paulista 10/10 Excellent "Nice room. Pool area good but pool too hot, but better than being too cold so maybe not too much of a problem. Dry sauna was too cold, steam sauna was fantastic. Excellent location on Paulista Avenue. Good breakfast" [](https://expedia.co.uk/Sao-Paulo-Hotels-Melia-Paulista.h1062869.Hotel-Information) ![Libertador Hotel](https://images.trvl-media.com/lodging/1000000/10000/9300/9291/d48bbed6_y.jpg) ### Libertador Hotel 10/10 Excellent "Staff are very helpful. Breakfast is good. Like it. " [](https://expedia.co.uk/Buenos-Aires-Hotels-Libertador-Hotel.h9291.Hotel-Information) ![NH Buenos Aires Tango](https://images.trvl-media.com/lodging/4000000/3310000/3307900/3307803/4c66c3b9_y.jpg) ### NH Buenos Aires Tango 10/10 Excellent "Everything in the room. Ok. " [](https://expedia.co.uk/Buenos-Aires-Hotels-NH-Buenos-Aires-Tango.h3307803.Hotel-Information) ![Hilton Buenos Aires](https://images.trvl-media.com/lodging/1000000/550000/547000/546934/d51890e8_y.jpg) ### Hilton Buenos Aires 10/10 Excellent "A bit more understanding of English in an American hotel would be great, other than that everything was wonderful." [](https://expedia.co.uk/Buenos-Aires-Hotels-Hilton-Buenos-Aires.h546934.Hotel-Information) ![Windsor Asturias Hotel](https://images.trvl-media.com/lodging/2000000/1780000/1775600/1775573/0ca96436_y.jpg) ### Windsor Asturias Hotel 10/10 Excellent "The room was very comfortable, the staff was very corteus and helpful. Leonardo in the restaurant was extremely corteus and attend us with much care. Carla in the front desk was very helpful." [](https://expedia.co.uk/Rio-De-Janeiro-Hotels-Windsor-Asturias-Hotel.h1775573.Hotel-Information) ![Amérian Buenos Aires](https://images.trvl-media.com/lodging/1000000/430000/428400/428308/aa690b11_y.jpg) ### Amérian Buenos Aires 10/10 Excellent "It was clean and nice. Me and my brother enjoyed our stay. The staff was also very helpful and pleasant." [](https://expedia.co.uk/Buenos-Aires-Hotels-Amerian-Buenos-Aires-Park-Hotel.h428308.Hotel-Information) ![Rochester Classic](https://images.trvl-media.com/lodging/1000000/20000/16300/16239/25f2f467_y.jpg) ### Rochester Classic 10/10 Excellent "Mis padres estuvieron muy contentos con el servicio del hotel, el personal fue muy amable y colaborativo. " [](https://expedia.co.uk/Buenos-Aires-Hotels-Rochester-Classic.h16239.Hotel-Information)