Title: South America Safari Hotels, : South America Hotel Guide | Expedia.co.uk [South America Travel Guide](https://expedia.co.uk/South-America.dx6023117)[South America Hotels](https://expedia.co.uk/Destinations-In-South-America.d6023117.Hotel-Destinations)[Holiday Rentals in South America](https://expedia.co.uk/Destinations-In-South-America.d6023117.Holiday-Rental-Destinations)[South America Flights](https://expedia.co.uk/Destinations-In-South-America.d6023117.Flight-Destinations)[South America Car Hire](https://expedia.co.uk/Destinations-In-South-America.d6023117.Car-Hire-Destinations)[South America Holidays](https://expedia.co.uk/South-America.d6023117.Holidays-City-Breaks) ![Cusco featuring a ruin, heritage architecture and a house](https://images.trvl-media.com/place/941/8118e1a4-6ad8-49e0-b1b9-dbc505b8c6d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/941/8118e1a4-6ad8-49e0-b1b9-dbc505b8c6d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South America Safari Hotels Tonight [10 Feb - 11 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South America hotels with on-site safari ![Standard Single Room | Water view](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/c138cc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/7188dc19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/6c584756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/5000000/4480000/4478500/4478459/9eb5534e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazon Tupana Jungle Lodge [](https://www.expedia.co.uk/Careiro-Hotels-Amazon-Tupana-Jungle-Lodge.h4478459.Hotel-Information) Careiro 9.4/10 Exceptional (19 reviews) "I like this hotel a lot I had fun and met a lot of new and friendly people including the staff. All staff was very friendly and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldo [](https://www.expedia.co.uk/Careiro-Hotels-Amazon-Tupana-Jungle-Lodge.h4478459.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/97191226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/ae54fce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/49d342c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/15000000/15000000/14992500/14992440/a9c65e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tulipanes Apart de Mar [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Los-Tulipanes-Apart-De-Mar.h14992440.Hotel-Information) Puerto Madryn 9.4/10 Exceptional (8 reviews) "Very helpful staff, cozy room, easy walk to beach and restaurants. Breakfast good but selection limited to beads,fruit, juice, kefir, and cereal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Los-Tulipanes-Apart-De-Mar.h14992440.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/be26125c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/e77418ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shared Dormitory, Mixed Dorm, Shared Bathroom (6 people) | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/a7035cfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6120000/6116900/6116802/420af2a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Pueblo Hostel [](https://www.expedia.co.uk/Mendoza-Hotels-Casa-Pueblo-Hostel.h6116802.Hotel-Information) Mendoza 8.0/10 Very good (11 reviews) "Great owners! Spent two days in a family atmosphere. Fortaleza is the champion ;)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Mendoza-Hotels-Casa-Pueblo-Hostel.h6116802.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1075x0y0-ee802024.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1075x0y0-b1ac081f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1076x0y0-99ca0e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/15000000/14890000/14883000/14882964/w1616h1076x0y0-b04af008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Curassow Amazon Lodge [](https://www.expedia.co.uk/Fernando-Lores-Hotels-Curassow-Amazon-Lodge.h14882964.Hotel-Information) Fernando Lores 10/10 Exceptional (1 review) "I am a biologist and I loved the experience at this lodge. The rooms were comfortable with quality sheets and towels changed daily. The food is excellent and prepared from local jungle resources. The guide spoke good English and was very knowledgeable about the local flora and fauna of which we saw lots. We were picked up at the airport and dropped off there afterwards. This company under Leon is very well organised. The lodge is located 3 hours by boat from Iquitos and has no internet and... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Elenab [](https://www.expedia.co.uk/Fernando-Lores-Hotels-Curassow-Amazon-Lodge.h14882964.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/7676c3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/576c14d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/e1e551d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/6000000/5430000/5426800/5426745/b0d3aef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Millaray [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Millaray.h5426745.Hotel-Information) Providencia 7.8/10 Good (15 reviews) "Reserva via telefonica y cuando llegue no estaba mi cupo ni tampoco se esmeraron en buscar solucion, quede sin hospedaje hasta buscar un nuevo hotel. Pesimo servicio." ![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg) andres [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Millaray.h5426745.Hotel-Information) ![Breakfast, lunch, dinner served; Regional cuisine ](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/4492a725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/65c3a867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/d24115ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16650000/16642600/16642518/b2337e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Isamar Galapagos Beachfront [](https://www.expedia.co.uk/Puerto-Villamil-Hotels-Isamar-Hotel.h16642518.Hotel-Information) Puerto Villamil 9.0/10 Wonderful (60 reviews) "Staff were very nice and helpful. Located on a beautiful beach. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann [](https://www.expedia.co.uk/Puerto-Villamil-Hotels-Isamar-Hotel.h16642518.Hotel-Information) ![Standard Quadruple Room | Premium bedding, pillow-top beds, blackout curtains, rollaway beds](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/75ecb5e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/fff9a37c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/0f500513.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9410000/9404800/9404761/b256fdc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nuevo Hotel Misiones [](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Nuevo-Hotel-Misiones.h9404761.Hotel-Information) Puerto Iguazú 6.6/10 (49 reviews) "Foi muito bom, otima localizacao" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) ana carolina [](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Nuevo-Hotel-Misiones.h9404761.Hotel-Information) ![Room, Ocean View | Premium bedding, minibar, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/6c0094e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fishing](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/9fe11b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Beachside | Terrace/patio](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/0372817c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach towels, snorkelling](https://images.trvl-media.com/lodging/19000000/18350000/18346100/18346042/f118dc8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### RAYENTRAY OCEANO [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Oceano-Patagonia-Wild-Coast-Residence.h18346042.Hotel-Information) Puerto Pirámides 8.4/10 Very good (70 reviews) "Staff was helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas £104 12 Feb - 13 Feb [](https://www.expedia.co.uk/Puerto-Madryn-Hotels-Oceano-Patagonia-Wild-Coast-Residence.h18346042.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25®ionId=6023117&adults=2&recreation_group_explore=safari_on_site&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Safari-Hotel.0-0-d6023117-tsafarihotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Safari-Hotel.0-0-d6023117-tsafarihotel.Hotel-Filter-Destinations) ## Top South America Hotel Reviews ![Lennox Hotel Buenos Aires](https://images.trvl-media.com/lodging/5000000/4190000/4182700/4182634/ffb5b7b3_y.jpg) ### Lennox Hotel Buenos Aires 10/10 Excellent "Staff was very nice. Room was perfect for me. They offered to change my room quickly once, but I told them thanks but no thanks. About 5 minute to a more street. About a 7 minute walk to a place called “The Temple Club”. If you have time definitely go there! Different tickets for live performances and so many restaurants to choose from too. It’s lively and people dress nice too. This hotel is on the famous street called guitar street. I would go back to this hotel. " [](https://expedia.co.uk/Buenos-Aires-Hotels-Lennox-Hotel-Buenos-Aires.h4182634.Hotel-Information) ![NH Buenos Aires Tango](https://images.trvl-media.com/lodging/4000000/3310000/3307900/3307803/4c66c3b9_y.jpg) ### NH Buenos Aires Tango 10/10 Excellent "Great room with a nice view and balcony " [](https://expedia.co.uk/Buenos-Aires-Hotels-NH-Buenos-Aires-Tango.h3307803.Hotel-Information) ![Hilton Buenos Aires](https://images.trvl-media.com/lodging/1000000/550000/547000/546934/d51890e8_y.jpg) ### Hilton Buenos Aires 10/10 Excellent "Great location, spacious room, very clean" [](https://expedia.co.uk/Buenos-Aires-Hotels-Hilton-Buenos-Aires.h546934.Hotel-Information) ![Melia Paulista](https://images.trvl-media.com/lodging/2000000/1070000/1062900/1062869/a90ff2a9_y.jpg) ### Melia Paulista 10/10 Excellent "The hotel is a great place to experience the Times Square like atmosphere of Avenida Paulista. Everything is within walking distance from the hotel and the staff are very friendly and helpful. Rooms and everything like pool & spa are spotless. I definitely recommend this hotel to anyone travelling to Sao Paulo I would certainly return anytime. Jason, Victoria, BC, Canada " [](https://expedia.co.uk/Sao-Paulo-Hotels-Melia-Paulista.h1062869.Hotel-Information) ![Libertador Hotel](https://images.trvl-media.com/lodging/1000000/10000/9300/9291/d48bbed6_y.jpg) ### Libertador Hotel 10/10 Excellent "Hotel was fantastic. Great staff, super friendly and everything was clean. The rooftop pool was amazing. Check in and check out take way longer than they should... there should be an express checkout so you don't wait 20 minutes behind people checking in to leave a key and confirm you didn't drink anything in the fridge." [](https://expedia.co.uk/Buenos-Aires-Hotels-Libertador-Hotel.h9291.Hotel-Information) ![InterContinental São Paulo by IHG](https://images.trvl-media.com/lodging/1000000/200000/198400/198375/242e7b38_y.jpg) ### InterContinental São Paulo by IHG 10/10 Excellent "Excelentes acomodações, tudo funcionando e limpo. O café da manhã é algo que precisa ser mencionado e elogiado, fartura na quantidade e qualidade dos itens oferecidos. O atendimento dos garçons também deve ser destacado, Raimundo nos atendeu de forma cordial, intencional e rápida. Aos domingos, uma igreja presbiteriana funciona no local, o que é ótimo pra quem está em trânsito aos domingos. " [](https://expedia.co.uk/Sao-Paulo-Hotels-InterContinental-Sao-Paulo.h198375.Hotel-Information) ![Amérian Buenos Aires](https://images.trvl-media.com/lodging/1000000/430000/428400/428308/aa690b11_y.jpg) ### Amérian Buenos Aires 10/10 Excellent "Quarto estava sem cadeira na mesa de trabalho. Não havia travesseiro extras disponíveis (apenas 2). Banheira sem condições de uso por faltar tampa na drenagem. Argumentaram ser uma medida ecológica. Muito estranho. " [](https://expedia.co.uk/Buenos-Aires-Hotels-Amerian-Buenos-Aires-Park-Hotel.h428308.Hotel-Information) ![Regal Pacific Buenos Aires](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246568/a11bbed3_y.jpg) ### Regal Pacific Buenos Aires 10/10 Excellent "The staff are very courteous and experienced. Breakfast was excellent. The clean swimming pool was a bonus." [](https://expedia.co.uk/Buenos-Aires-Hotels-Regal-Pacific-Buenos-Aires.h1246568.Hotel-Information) ![Almacruz Hotel y Centro de Convenciones](https://images.trvl-media.com/lodging/1000000/10000/1500/1496/b4c00de4_y.jpg) ### Almacruz Hotel y Centro de Convenciones 10/10 Excellent "Room was very spacious and great aircon. Staff were lovely and we enjoyed our time immensely by the pool on the sun. Great breakfast as well. Maybe a bit on the dates side and the gym was tiny with only the treadmill working." [](https://expedia.co.uk/Santiago-Hotels-Almacruz-Hotel-Y-Centro-De-Convenciones.h1496.Hotel-Information)