£25 Cheap Flights to Santiago

Popular airlines to Santiago

  • LATAM Airlines Group

    LATAM Airlines Group

  • Sky Airlines

    Sky Airlines

  • B & H Airlines

    B & H Airlines

  • Avianca

    Avianca

  • Delta

    Delta

  • American Airlines

    American Airlines

  • Aeromexico

    Aeromexico

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Cheap round-trip flights to Santiago

Prices were available within the past 7 days and start at £25 for one-way flights and £49 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Sun, 4 Jan - Mon, 2 Feb
PEM
Puerto Maldonado
CUZ
Cusco
£49 Return, found 2 days ago
£49
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, 4 Jan from Puerto Maldonado to Cusco, returning Mon, 2 Feb, priced at £49 found 2 days ago
LATAM Airlines Group
Sun, 2 Nov - Fri, 28 Nov
PEM
Puerto Maldonado
CUZ
Cusco
£51 Return, found 3 days ago
£51
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 2 Nov from Puerto Maldonado to Cusco, returning Fri, 28 Nov, priced at £51 found 3 days ago
LATAM Airlines Group
Sun, 2 Nov - Fri, 28 Nov
PEM
Puerto Maldonado
CUZ
Cusco
£54 Return, found 3 days ago
£54
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 2 Nov from Puerto Maldonado to Cusco, returning Fri, 28 Nov, priced at £54 found 3 days ago
LATAM Airlines Group
Sun, 2 Nov - Fri, 28 Nov
PEM
Puerto Maldonado
CUZ
Cusco
£55 Return, found 3 days ago
£55
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 2 Nov from Puerto Maldonado to Cusco, returning Fri, 28 Nov, priced at £55 found 3 days ago
LATAM Airlines Group
Sun, 4 Jan - Mon, 2 Feb
PEM
Puerto Maldonado
CUZ
Cusco
£60 Return, found 2 days ago
£60
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, 4 Jan from Puerto Maldonado to Cusco, returning Mon, 2 Feb, priced at £60 found 2 days ago
LATAM Airlines Group
Sun, 2 Nov - Fri, 28 Nov
PEM
Puerto Maldonado
CUZ
Cusco
£62 Return, found 3 days ago
£62
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 2 Nov from Puerto Maldonado to Cusco, returning Fri, 28 Nov, priced at £62 found 3 days ago
SKY AIRLINE
Sun, 4 Jan - Mon, 2 Feb
PEM
Puerto Maldonado
CUZ
Cusco
£71 Return, found 2 days ago
£71
Return
found 2 days ago
Select SKY AIRLINE flight, departing Sun, 4 Jan from Puerto Maldonado to Cusco, returning Mon, 2 Feb, priced at £71 found 2 days ago
avianca
Fri, 1 May - Thu, 7 May
SJO
San José
CUZ
Cusco
£287 Return, found 1 day ago
£287
Return
found 1 day ago
Select avianca flight, departing Fri, 1 May from San José to Cusco, returning Thu, 7 May, priced at £287 found 1 day ago
Sky Airline Peru
Wed, 1 Oct - Mon, 6 Oct
MIA
Miami
CUZ
Cusco
£330 Return, found 14 hours ago
£330
Return
found 14 hours ago
Select Sky Airline Peru flight, departing Wed, 1 Oct from Miami to Cusco, returning Mon, 6 Oct, priced at £330 found 14 hours ago
Aerolineas Argentinas
Mon, 1 Dec - Sat, 6 Dec
AEP
Buenos Aires
CUZ
Cusco
£390 Return, found 3 days ago
£390
Return
found 3 days ago
Select Aerolineas Argentinas flight, departing Mon, 1 Dec from Buenos Aires to Cusco, returning Sat, 6 Dec, priced at £390 found 3 days ago

Top tips for booking flights to Santiago from UK

Get ready to fly to Santiago

Prepare your luggage and book your flights to Santiago with Expedia. We offer a seamless flight booking experience, with a wide range of Santiago plane tickets to choose from. If you need help finding some of the best deals for cheap flights to Santiago in 2025, we are always available to assist you. Book your flights to Santiago today and let the adventure begin!

Find the best tickets to Santiago

To find some of the best tickets to Santiago in 2025, use Expedia's powerful search engine to compare dates and the different departure and arrival airports for your trip. Whether you're after direct flights to Santiago or last-minute flights to Santiago, you can filter and sort your search results, making it easy to find the ideal flight to Santiago.

Airlines fly to Santiago

There are 20 different airlines that fly to Santiago including some of the most trusted names in the business. To book flights to Santiago with your favourite airline, take a look at Expedia's flight listings and try out different dates to find some of the best Santiago plane tickets.

Find the cheapest flights to Santiago

By booking early you may find some of the best deals for Santiago flights from the UK, including Santiago direct flights. You can usually find affordable and cheap flights to Santiago, whether one-way from £25 or round-trip from £49, with Expedia if you book your trip far enough in advance.

Find the best airports for cheap flights to Santiago

Try searching for different Santiago airports with Expedia to find some of the cheapest flights to Santiago. Flights from Puerto Maldonado (PEM) to Cusco (CUZ) usually have the lowest price from £25.

Why book your flights to Santiago with Expedia

Expedia offers great deals on Santiago air fares from £25 to cater to every budget. Not only is Expedia one of the top platforms to book flights to Santiago from the UK, it is also your one-stop shop for booking hotels, car rentals, and more.

 

*Prices and availability are subject to change. Additional terms apply.

Santiago Flights Information

Airlines serving
LATAM Airlines Group, SKY AIRLINE, avianca, Sky Airline Peru, Aerolineas Argentinas
Roundtrip price
from £49

Frequently asked questions

How do I find cheap flights to Santiago that have flexible change policies?
By using our helpful "No change fee" filter, that's how. Simply enter your dates and other details, click the "Search" button, then tick the checkbox directly below the "Flexible change policies" subheading (top left-hand side of your screen). Expedia makes it a snap to find affordable, flexible flights to Santiago.
How can I find cheap tickets to Santiago?
You'll always walk away with an epic deal with Expedia, but our "flexible dates" search function makes it even easier. Enter your preferred travel date, then check the flexible dates box above to compare prices for nearby days. £49 was the cheapest price for a flight to Santiago in the last seven days.
How much is a flight to Santiago?
In the last seven days, round-trip airfares to Santiago sold for as low as £49 and peaked at £679. For one-way trips departing from Puerto Maldonado (PEM), the lowest price during this time was only £25.
When is the cheapest time to fly to Santiago?
Leave for Santiago early in the week and you'll usually be rewarded with lower-priced fares. Tuesday is known for being the cheapest day to jet off, followed closely by Monday. If you're hoping to avoid the priciest flights, stay away from Saturdays.
How much is a plane ticket to Santiago?
Fares ranged from £49 to £679 over the last seven days. When you're ready to book, we'll be ready to help you secure a fabulous deal to Santiago.
What months are the cheapest to book a flight to Santiago?
To snap up a low-cost flight to Santiago, try to book during February when ticket prices are at their cheapest. What time of year is expensive? In the USA, it's December.

Trending flights to Santiago

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Tue, 3 Feb - Tue, 10 Feb
MAN
Manchester
CUZ
Cusco
£679 Return, found 5 days ago
£679
Return
found 5 days ago
Select Iberia flight, departing Tue, 3 Feb from Manchester to Cusco, returning Tue, 10 Feb, priced at £679 found 5 days ago
*Available to Expedia members.