Title: Top Hotels in Santa María Department - Compare Santa María Department Hotels | Expedia.co.uk [Holiday Rentals in Santa María Department](https://expedia.co.uk/Destinations-In-Santa-Maria-Department.d553248635975751146.Holiday-Rental-Destinations)[Santa María Department Car Hire](https://expedia.co.uk/Destinations-In-Santa-Maria-Department.d553248635975751146.Car-Hire-Destinations)[Santa María Department Holidays](https://expedia.co.uk/Santa-Maria-Department.d553248635975751146.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best Santa María Department Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975751146&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975751146&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975751146&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975751146&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa María Department hotels ![Restaurant](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/67626ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/ab3d4d9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, towels, soap, shampoo](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/7a040ec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/a3abdf5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Altos de Amaicha [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-Hotel-Boutique-Altos-De-Amaicha.h113962887.Hotel-Information) Amaicha Del Valle [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-Hotel-Boutique-Altos-De-Amaicha.h113962887.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/a8c893d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/11188a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/43d9e583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Internet, bed sheets](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/c74fb133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabaña Achalay 1 – Refugio en Santa María [](https://www.expedia.co.uk/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342849.Hotel-Information) Santa María [](https://www.expedia.co.uk/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342849.Hotel-Information) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/735a6640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/81a9b037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/8bf5aa3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/f77407d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eco Glamping Amaicha del Valle [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-Eco-Glamping-Amaicha-Del-Valle.h95733324.Hotel-Information) Amaicha del Valle £135 22 Jan - 23 Jan 2026 [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-Eco-Glamping-Amaicha-Del-Valle.h95733324.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/bc02d8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/e17f651f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/7528be11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/1f617373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Esmeralda: the star accommodation in Amaicha del Valle [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-La-Esmeralda-The-Star-Accommodation-In-Amaicha-Del-Valle.h116221596.Hotel-Information) Amaicha del Valle [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-La-Esmeralda-The-Star-Accommodation-In-Amaicha-Del-Valle.h116221596.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/5dd5d6b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/4fd5b67a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/832c81a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/eaf6dd15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabaña Achalay 1 – Refugio en Santa María [](https://www.expedia.co.uk/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342882.Hotel-Information) Santa María [](https://www.expedia.co.uk/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342882.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/6486b328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/7c51ec70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/5e8a57d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/8e1e52ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cerco del Trigo. Total peace [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-Vrbo-Property.h116221625.Hotel-Information) Amaicha del Valle [](https://www.expedia.co.uk/Amaicha-Del-Valle-Hotels-Vrbo-Property.h116221625.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08®ionId=553248635975751146&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Maria-Department.d553248635975751146.Hotel-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Maria-Department.d553248635975751146.Hotel-Destinations) ## Top Santa María Department Hotel Reviews ![Patios de Cafayate - Wine Hotel & Restaurant](https://images.trvl-media.com/lodging/2000000/1330000/1322200/1322111/b4b3fdad_y.jpg) ### Patios de Cafayate - Wine Hotel & Restaurant 10/10 Excellent "Fabulous in all respects" [](https://expedia.co.uk/Cafayate-Hotels-Patios-De-Cafayate-Wine-Hotel.h1322111.Hotel-Information) ![Piattelli Wine Resort](https://images.trvl-media.com/lodging/85000000/84400000/84390700/84390617/636f7b9c_y.jpg) ### Piattelli Wine Resort 10/10 Excellent "We booked one night here last minute as part of our honeymoon trip through Argentina - and wow, did we wish we stayed longer. Grounds are pristine, staff are super friendly and knowledgeable about the wine and area of Cafayate. In our short time, we were able to enjoy a wine and chocolate tasting (trust me, this is worth it), gin and vodka tasting, a lovely dinner at Aura, a fire in the upstairs terrace fireplace, massage, and an incredible breakfast spread." [](https://expedia.co.uk/Cafayate-Hotels-Piattelli-Wine-Resort.h84390617.Hotel-Information) ![HOTEL PLAZA CAFAYATE](https://images.trvl-media.com/lodging/112000000/111210000/111207700/111207630/0814b150_y.jpg) ### HOTEL PLAZA CAFAYATE 10/10 Excellent "Very quaint and perfect location " [](https://expedia.co.uk/Cafayate-Hotels-HOTEL-PLAZA-CAFAYATE.h111207630.Hotel-Information) ![Buena Vid by Chadel Management](https://images.trvl-media.com/lodging/102000000/101930000/101920100/101920087/0c5f512f_y.jpg) ### Buena Vid by Chadel Management 10/10 Excellent "Very nice place spacious room and have a kitchenand supplies. Location is very good. Close to town and easy to parking. Everything is wonderful." [](https://expedia.co.uk/Cafayate-Hotels-Buena-Vid-By-Chadel-Management.h101920087.Hotel-Information) ![El Porvenir Wine Lodge](https://images.trvl-media.com/lodging/104000000/103570000/103566700/103566671/26248c90_y.jpg) ### El Porvenir Wine Lodge 10/10 Excellent "Beautiful and quiet spot but still within walking distance of the square. Couldn't ask for a better view. And the food in their restaurant was terrific. " [](https://expedia.co.uk/Cafayate-Hotels-El-Porvenir-Wine-Lodge.h103566671.Hotel-Information) ![VIEJA POSADA HOTEL HISTORICO](https://images.trvl-media.com/lodging/93000000/92400000/92391900/92391824/ce692ac3_y.jpg) ### VIEJA POSADA HOTEL HISTORICO 8/10 Good "Charmante auberge. Petite chambre et salle de bain mais les espaces communs sont accueillants et authentiques. Nous avons qu’une nuit." [](https://expedia.co.uk/Cafayate-Hotels-VIEJA-POSADA-HOTEL-HISTORICO.h92391824.Hotel-Information) ![Villa Vicuña Hotel Boutique Cafayate](https://images.trvl-media.com/lodging/13000000/12710000/12701700/12701655/6a816f69_y.jpg) ### Villa Vicuña Hotel Boutique Cafayate 10/10 Excellent "After staying at the sister-hotel in Salta, we knew this Cafayate hotel would be lovely. This courtyard and dining areas were delightful, and the room was clean, sizeable and comfortable. We enjoyed the breakfast and appreciated the responsiveness of the reception staff. Particularly, we were grateful for the staff's flexibility finding us a room for an extra night when a road closure elsewhere in Salta Province resulted in our need to extend our stay for a day." [](https://expedia.co.uk/Cafayate-Hotels-Villa-Vicuna-Hotel-Boutique-Cafayate.h12701655.Hotel-Information) ![Hotel Asturias](https://images.trvl-media.com/lodging/4000000/3490000/3489200/3489185/dde0c73a_y.jpg) ### Hotel Asturias 8/10 Good "Hotel has nice facade and in good location just off the main plaza. Deluxe double room was spacious, albeit a little old and plain and in need of some redecoration. Good air con. Mini fridge but no kettle. Need to ask to borrow hairdryer at reception. Breakfast was usual Argentine buffet fare with option of cooked to order eggs. On site parking. Small pool with loungers that even had cushions. Small, poor gym which was very hot. Spa - got a one hour massage for 20,000 pesos. Hotel did a bag of laundry for us for around 15,000 pesos (approx 10 pieces underwear, 4 shorts and 8 T shirts) which i thought was a reasonable price for a hotel. Staff try to be helpful but only speak Spanish. Overall a good option for a few nights even if a little pricey for a 3 star." [](https://expedia.co.uk/Cafayate-Hotels-Hotel-Asturias.h3489185.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Santa María Department - [Santa Maria Hotels ](https://expedia.co.uk/Santa-Maria-Hotels.d6348211.Travel-Guide-Hotels) - [Loro Huasi Hotels ](https://expedia.co.uk/Loro-Huasi-Hotels.d553248635924012675.Travel-Guide-Hotels) - [San José Hotels ](https://expedia.co.uk/San-Jose-Hotels.d553248635924012031.Travel-Guide-Hotels) - [Fuerte Quemado Hotels ](https://expedia.co.uk/Fuerte-Quemado-Hotels.d553248635924012235.Travel-Guide-Hotels) ### Explore more hotels - [Patios de Cafayate - Wine Hotel & Restaurant ](https://expedia.co.uk/Cafayate-Hotels-Patios-De-Cafayate-Wine-Hotel.h1322111.Hotel-Information) - [Piattelli Wine Resort ](https://expedia.co.uk/Cafayate-Hotels-Piattelli-Wine-Resort.h84390617.Hotel-Information) - [El Porvenir Wine Lodge ](https://expedia.co.uk/Cafayate-Hotels-El-Porvenir-Wine-Lodge.h103566671.Hotel-Information) - [HOTEL PLAZA CAFAYATE ](https://expedia.co.uk/Cafayate-Hotels-HOTEL-PLAZA-CAFAYATE.h111207630.Hotel-Information) - [Hotel Cafayate ](https://expedia.co.uk/Cafayate-Hotels-Hotel-Cafayate.h117152667.Hotel-Information) - [Buena Vid by Chadel Management ](https://expedia.co.uk/Cafayate-Hotels-Buena-Vid-By-Chadel-Management.h101920087.Hotel-Information) - [VIEJA POSADA HOTEL HISTORICO ](https://expedia.co.uk/Cafayate-Hotels-VIEJA-POSADA-HOTEL-HISTORICO.h92391824.Hotel-Information) - [Villa Vicuña Hotel Boutique Cafayate ](https://expedia.co.uk/Cafayate-Hotels-Villa-Vicuna-Hotel-Boutique-Cafayate.h12701655.Hotel-Information) - [Hotel Asturias ](https://expedia.co.uk/Cafayate-Hotels-Hotel-Asturias.h3489185.Hotel-Information) [See a list of all hotels in Santa María Department](https://expedia.co.uk/All-Santa-Maria-Department-Hotels.d553248635975751146.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Santa María Department on Expedia.com.ar ](https://www.expedia.com.ar/Destinos-En-Departamento-Santa-Maria.d553248635975751146.Destinos-con-Hoteles) ### Expedia's Latest Trends Hotels - 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