Title: Top Hotels in La Serena - Compare La Serena Hotels | Expedia.co.uk [Holiday Rentals in La Serena](https://expedia.co.uk/Destinations-In-La-Serena.d553248635942949504.Holiday-Rental-Destinations)[La Serena Car Hire](https://expedia.co.uk/Destinations-In-La-Serena.d553248635942949504.Car-Hire-Destinations)[La Serena Holidays](https://expedia.co.uk/La-Serena.d553248635942949504.Holidays-City-Breaks) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best La Serena Hotels ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Serena Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&lodging=APARTMENT) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=PETS) ## Check prices for these dates Tonight [2 Oct - 3 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-10-02&endDate=2025-10-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Oct - 4 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-10-03&endDate=2025-10-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels La Serena ![Dining](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/f98081e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/eba7c27d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/fa8d5d43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 4 Bedrooms | Living area | Flat-screen TV, fireplace](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/cc02632c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Rural Casas De Las Regatas Castuera [](https://www.expedia.co.uk/Castuera-Hotels-Casa-Rural-Casas-De-Las-Regatas.h26825966.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/80f356ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/9bc2e881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/df9ca377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/d146d46e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Palomeque Rural House Sancti Spiritus 10/10 Exceptional (1) "En general todo ha sido sobresaliente" £145 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sancti-Spiritus-Hotels-Vrbo-Property.h75990503.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17®ionId=553248635942949504&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-La-Serena.d553248635942949504.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-La-Serena.d553248635942949504.Hotel-Destinations) ## Top La Serena Hotel Reviews ![Lantigua Casa Rural](//images.trvl-media.com/lodging/20000000/19570000/19565600/19565533/621f7b9d_y.jpg) ### Lantigua Casa Rural 10/10 Excellent " “Una estancia maravillosa. La casa es muy acogedora, perfectamente cuidada y con un ambiente tranquilo. La habitación estaba impecable y muy cómoda. El desayuno fue delicioso y preparado con mucho cariño. Los anfitriones son encantadores, siempre atentos y dispuestos a ayudar. Sin duda, un lugar para volver y recomendar.”" [](https://expedia.co.uk/Hinojosa-Del-Duque-Hotels-Lantigua-Casa-Rural.h19565533.Hotel-Information) ![Hotel Rural La Sinforosa](//images.trvl-media.com/lodging/25000000/24320000/24315800/24315721/aa5f39cc_y.jpg) ### Hotel Rural La Sinforosa 10/10 Excellent "Nice atmosphere, smiling and helpful staff. Excellent experience. Recommended." [](https://expedia.co.uk/Alange-Hotels-Hotel-Rural-La-Sinforosa.h24315721.Hotel-Information) ![Hotel Varinia Serena - Balneario de Alange](//images.trvl-media.com/lodging/23000000/22230000/22224800/22224741/512f16d8_y.jpg) ### Hotel Varinia Serena - Balneario de Alange 6/10 Okay "Good place." [](https://expedia.co.uk/Alange-Hotels-Hotel-Varinia-Serena-Balneario-De-Alange.h22224741.Hotel-Information) ![Hospedium Hotel Cortijo Santa Cruz](//images.trvl-media.com/lodging/4000000/3490000/3486800/3486729/43696b66_y.jpg) ### Hospedium Hotel Cortijo Santa Cruz 10/10 Excellent "Beautiful hotel, with its own style, it has a 360 beautiful view and has everything you would need. It is worth to drive and extra kilometer!" [](https://expedia.co.uk/Villanueva-De-La-Serena-Hotels-Hospedium-Hotel-Cortijo-Santa-Cruz.h3486729.Hotel-Information) ![Hotel Sol](//images.trvl-media.com/lodging/47000000/46950000/46940400/46940390/0eb9a638_y.jpg) ### Hotel Sol 2/10 Terrible "I canceled the booking. Hotel was closed when we arrived. I have to spend the night in the car with my 98 year father and two sisters. I want a refund. " [](https://expedia.co.uk/Penarroya-Pueblonuevo-Hotels-HOTEL-SOL.h46940390.Hotel-Information) ![Casa Rural la Pajarona](//images.trvl-media.com/lodging/24000000/23020000/23014500/23014486/06125595_y.jpg) ### Casa Rural la Pajarona 8/10 Good "The hotel itself is fantastic with its patio garden, wonderful sun terrace and lovely rooms but the owners were away for our stay so we had no bar or restaurant, and the swimming pool was covered over. We were let in and told we had to find our own food in the village which is harder than it sounds on a Sunday in Spain. We did find a little shop where we could buy some snacks and cans of drink for the afternoon and we were able to get an evening meal at the only bar which was open and serving later on but that's not the hassle which is welcome after a long day's travel. Had we known there would be no bar or food in the hotel we would not have booked at this time but could only go by what was shown in the Hotels app." [](https://expedia.co.uk/Siruela-Hotels-Casa-Rural-La-Pajarona.h23014486.Hotel-Information) ![Hospedium Hotel Triana](//images.trvl-media.com/lodging/23000000/22510000/22509300/22509266/a383bff6_y.jpg) ### Hospedium Hotel Triana 8/10 Good " Limpio, cómodo y accesible. " [](https://expedia.co.uk/Miajadas-Hotels-Hospedium-Hotel-Triana.h22509266.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in La Serena - [Cabeza del Buey Hotels](https://expedia.co.uk/Cabeza-Del-Buey-Hotels.d6357075.Travel-Guide-Hotels) - [Castuera Hotels](https://expedia.co.uk/Castuera-Hotels.d6357079.Travel-Guide-Hotels) - [Campanario Hotels](https://expedia.co.uk/Campanario-Hotels.d6357080.Travel-Guide-Hotels) - [Zalamea de la Serena Hotels](https://expedia.co.uk/Zalamea-De-La-Serena-Hotels.d3000389506.Travel-Guide-Hotels) - [Monterrubio de la Serena Hotels](https://expedia.co.uk/Monterrubio-De-La-Serena-Hotels.d553248633901378679.Travel-Guide-Hotels) - [La Coronada Hotels](https://expedia.co.uk/La-Coronada-Hotels.d553248633901348155.Travel-Guide-Hotels) - [Peñalsordo Hotels](https://expedia.co.uk/Penalsordo-Hotels.d553248633901344836.Travel-Guide-Hotels) - [Esparragosa de la Serena Hotels](https://expedia.co.uk/Esparragosa-De-La-Serena-Hotels.d553248633901370780.Travel-Guide-Hotels) - [Higuera de la Serena Hotels](https://expedia.co.uk/Higuera-De-La-Serena-Hotels.d6357144.Travel-Guide-Hotels) - [Magacela Hotels](https://expedia.co.uk/Magacela-Hotels.d6357083.Travel-Guide-Hotels) - [Benquerencia de la Serena Hotels](https://expedia.co.uk/Benquerencia-De-La-Serena-Hotels.d553248633901349609.Travel-Guide-Hotels) - [Malpartida de la Serena Hotels](https://expedia.co.uk/Malpartida-De-La-Serena-Hotels.d553248633901348048.Travel-Guide-Hotels) - [Quintana de la Serena Hotels](https://expedia.co.uk/Quintana-De-La-Serena-Hotels.d553248633901344591.Travel-Guide-Hotels) - [Zarza Capilla Hotels](https://expedia.co.uk/Zarza-Capilla-Hotels.d553248633901346812.Travel-Guide-Hotels) - [Valle de la Serena Hotels](https://expedia.co.uk/Valle-De-La-Serena-Hotels.d553248633901344764.Travel-Guide-Hotels) - [Capilla Hotels](https://expedia.co.uk/Capilla-Hotels.d553248633901348216.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Orellana Beach](https://expedia.co.uk/Orellana-Beach-Hotels.0-l553248626836817887-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Vegas Altas](https://expedia.co.uk/Don-Benito-Hotels-Vegas-Altas.h5089004.Hotel-Information) - [Gran Hotel Aqualange - Balneario de Alange](https://expedia.co.uk/Alange-Hotels-Gran-Hotel-Aqualange-Balneario-De-Alange.h11898892.Hotel-Information) - [Hotel Sol](https://expedia.co.uk/Penarroya-Pueblonuevo-Hotels-HOTEL-SOL.h46940390.Hotel-Information) - [Apartamentos Embalse de Orellana](https://expedia.co.uk/Orellana-La-Vieja-Hotels-Apartamentos-Embalse-De-Orellana.h30403593.Hotel-Information) - [Lantigua Casa Rural](https://expedia.co.uk/Hinojosa-Del-Duque-Hotels-Lantigua-Casa-Rural.h19565533.Hotel-Information) - [Hospedium Hotel Cortijo Santa Cruz](https://expedia.co.uk/Villanueva-De-La-Serena-Hotels-Hospedium-Hotel-Cortijo-Santa-Cruz.h3486729.Hotel-Information) - [Hotel Rural La Sinforosa](https://expedia.co.uk/Alange-Hotels-Hotel-Rural-La-Sinforosa.h24315721.Hotel-Information) - [Hotel Veracruz](https://expedia.co.uk/Don-Benito-Hotels-Hotel-Veracruz.h36065785.Hotel-Information) [See a list of all hotels in La Serena](https://expedia.co.uk/All-La-Serena-Hotels.d553248635942949504.Travel-Guide-City-All-Hotels) ### More ways to book - 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[Flights from Manchester to Minsk](https://expedia.co.uk/lp/flights/man/msq/manchester-to-minsk) - [Flights to Costa Tropical](https://expedia.co.uk/Destinations-In-Costa-Tropical.d3000692293.Flight-Destinations) - [Flights to Swansea](https://expedia.co.uk/Cheap-Flights-To-Swansea.d9958.Travel-Guide-Flights) Cars - [Convertible Car Hire in California](https://expedia.co.uk/Convertible-Car-Rentals-In-California.d206-tConvertible.Car-Rental-Destination-Class) Activities - [Things to do in La Marina Alta](https://expedia.co.uk/Things-To-Do-In-La-Marina-Alta.d553248625840561592.Travel-Guide-Activities) - [Things to do in Villeneuve-Loubet](https://expedia.co.uk/Things-To-Do-In-Villeneuve-Loubet.d5868.Travel-Guide-Activities) Packages - [Cathedral of Milan](https://expedia.co.uk/Cathedral-Of-Milan-Milan-Centre.d501802.Attraction) - [Plaza Mayor](https://expedia.co.uk/Plaza-Mayor-Madrid-Centro.d508457.Attraction) - [La Marina Alta Holidays](https://expedia.co.uk/La-Marina-Alta.d553248625840561592.Holidays-City-Breaks) - [Scheveningen Beach](https://expedia.co.uk/Scheveningen-Beach-Scheveningen.d6064231.Attraction) - [Malacca Holidays](https://expedia.co.uk/Malacca.d6131368.Holidays-City-Breaks) - [Costa Tropical Holidays](https://expedia.co.uk/Costa-Tropical.d3000692293.Holidays-City-Breaks) General - [Visit La Marina Alta](https://expedia.co.uk/La-Marina-Alta.dx553248625840561592) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)