Title: Top Hotels in La Serena - Compare La Serena Hotels | Expedia.co.uk [Holiday Rentals in La Serena](https://expedia.co.uk/Destinations-In-La-Serena.d553248635942949504.Holiday-Rental-Destinations)[La Serena Car Hire](https://expedia.co.uk/Destinations-In-La-Serena.d553248635942949504.Car-Hire-Destinations)[La Serena Holidays](https://expedia.co.uk/La-Serena.d553248635942949504.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best La Serena Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Serena Pool [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-11-30&d1=2025-11-30&endDate=2025-12-02&d2=2025-12-02&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-11-30&d1=2025-11-30&endDate=2025-12-02&d2=2025-12-02&lodging=APARTMENT) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-11-30&d1=2025-11-30&endDate=2025-12-02&d2=2025-12-02&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Serena%2C+Extremadura%2C+Spain®ionId=553248635942949504&latLong=38.748677%2C-5.47275&adults=2&startDate=2025-11-30&d1=2025-11-30&endDate=2025-12-02&d2=2025-12-02&amenities=PETS) ## Check prices for these dates Tonight [16 Nov - 17 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-11-16&endDate=2025-11-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [17 Nov - 18 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-11-17&endDate=2025-11-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635942949504&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels La Serena ![Dining](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/f98081e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 4 Bedrooms | Living area | Flat-screen TV, fireplace](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/cc02632c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/fa8d5d43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/27000000/26830000/26826000/26825966/eba7c27d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Rural Casas De Las Regatas Castuera [](https://www.expedia.co.uk/Castuera-Hotels-Casa-Rural-Casas-De-Las-Regatas.h26825966.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/80f356ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/df9ca377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/41728992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/76000000/76000000/75990600/75990503/d146d46e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Palomeque Rural House Sancti Spiritus 10/10 Exceptional (1) "En general todo ha sido sobresaliente" ![Spain](https://a.travel-assets.com/egds/marks/flags/es.svg) EPHRAIM W. £147 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Sancti-Spiritus-Hotels-Vrbo-Property.h75990503.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01®ionId=553248635942949504&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-La-Serena.d553248635942949504.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-La-Serena.d553248635942949504.Hotel-Destinations) ## Top La Serena Hotel Reviews ### Hotel Rural La Sinforosa 10/10 Excellent "Very friendly staff, nice courtyard for a drink, room was spacious and comfortable. We didn’t try the jacuzzi bath! Breakfast was a little disappointing apart from the diy freshly squeezed orange juice. Good overnight stop. " [](https://expedia.co.uk/Alange-Hotels-Hotel-Rural-La-Sinforosa.h24315721.Hotel-Information) ![Lantigua Casa Rural](//images.trvl-media.com/lodging/20000000/19570000/19565600/19565533/621f7b9d_y.jpg) ### Lantigua Casa Rural 10/10 Excellent " “Una estancia maravillosa. La casa es muy acogedora, perfectamente cuidada y con un ambiente tranquilo. La habitación estaba impecable y muy cómoda. El desayuno fue delicioso y preparado con mucho cariño. Los anfitriones son encantadores, siempre atentos y dispuestos a ayudar. Sin duda, un lugar para volver y recomendar.”" [](https://expedia.co.uk/Hinojosa-Del-Duque-Hotels-Lantigua-Casa-Rural.h19565533.Hotel-Information) ### Hotel Varinia Serena - Balneario de Alange 6/10 Okay "Good place." [](https://expedia.co.uk/Alange-Hotels-Hotel-Varinia-Serena-Balneario-De-Alange.h22224741.Hotel-Information) ### Hospedium Hotel Cortijo Santa Cruz 10/10 Excellent "Beautiful hotel, with its own style, it has a 360 beautiful view and has everything you would need. It is worth to drive and extra kilometer!" [](https://expedia.co.uk/Villanueva-De-La-Serena-Hotels-Hospedium-Hotel-Cortijo-Santa-Cruz.h3486729.Hotel-Information) ![Hotel Sol](//images.trvl-media.com/lodging/47000000/46950000/46940400/46940390/0eb9a638_y.jpg) ### Hotel Sol 2/10 Terrible "I canceled the booking. Hotel was closed when we arrived. I have to spend the night in the car with my 98 year father and two sisters. I want a refund. " [](https://expedia.co.uk/Penarroya-Pueblonuevo-Hotels-HOTEL-SOL.h46940390.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in La Serena - [Castuera Hotels](https://expedia.co.uk/Castuera-Hotels.d6357079.Travel-Guide-Hotels) - [Cabeza del Buey Hotels](https://expedia.co.uk/Cabeza-Del-Buey-Hotels.d6357075.Travel-Guide-Hotels) - [Quintana de la Serena Hotels](https://expedia.co.uk/Quintana-De-La-Serena-Hotels.d553248633901344591.Travel-Guide-Hotels) - [Zalamea de la Serena Hotels](https://expedia.co.uk/Zalamea-De-La-Serena-Hotels.d3000389506.Travel-Guide-Hotels) - [Campanario Hotels](https://expedia.co.uk/Campanario-Hotels.d6357080.Travel-Guide-Hotels) - [Monterrubio de la Serena Hotels](https://expedia.co.uk/Monterrubio-De-La-Serena-Hotels.d553248633901378679.Travel-Guide-Hotels) - [Higuera de la Serena Hotels](https://expedia.co.uk/Higuera-De-La-Serena-Hotels.d6357144.Travel-Guide-Hotels) - [Esparragosa de la Serena Hotels](https://expedia.co.uk/Esparragosa-De-La-Serena-Hotels.d553248633901370780.Travel-Guide-Hotels) - [La Coronada Hotels](https://expedia.co.uk/La-Coronada-Hotels.d553248633901348155.Travel-Guide-Hotels) - [Peñalsordo Hotels](https://expedia.co.uk/Penalsordo-Hotels.d553248633901344836.Travel-Guide-Hotels) - [Benquerencia de la Serena Hotels](https://expedia.co.uk/Benquerencia-De-La-Serena-Hotels.d553248633901349609.Travel-Guide-Hotels) - [Malpartida de la Serena Hotels](https://expedia.co.uk/Malpartida-De-La-Serena-Hotels.d553248633901348048.Travel-Guide-Hotels) - [Magacela Hotels](https://expedia.co.uk/Magacela-Hotels.d6357083.Travel-Guide-Hotels) - [Zarza Capilla Hotels](https://expedia.co.uk/Zarza-Capilla-Hotels.d553248633901346812.Travel-Guide-Hotels) - [Valle de la Serena Hotels](https://expedia.co.uk/Valle-De-La-Serena-Hotels.d553248633901344764.Travel-Guide-Hotels) - [Capilla Hotels](https://expedia.co.uk/Capilla-Hotels.d553248633901348216.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Orellana Beach](https://expedia.co.uk/Orellana-Beach-Hotels.0-l553248626836817887-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Vegas Altas](https://expedia.co.uk/Don-Benito-Hotels-Vegas-Altas.h5089004.Hotel-Information) - [Hospedium Hotel Cortijo Santa Cruz](https://expedia.co.uk/Villanueva-De-La-Serena-Hotels-Hospedium-Hotel-Cortijo-Santa-Cruz.h3486729.Hotel-Information) - [Hotel Sol](https://expedia.co.uk/Penarroya-Pueblonuevo-Hotels-HOTEL-SOL.h46940390.Hotel-Information) - [Hotel Rural La Sinforosa](https://expedia.co.uk/Alange-Hotels-Hotel-Rural-La-Sinforosa.h24315721.Hotel-Information) - [Hospedium Hotel Triana](https://expedia.co.uk/Miajadas-Hotels-Hospedium-Hotel-Triana.h22509266.Hotel-Information) - [Gran Hotel Aqualange - Balneario de Alange](https://expedia.co.uk/Alange-Hotels-Gran-Hotel-Aqualange-Balneario-De-Alange.h11898892.Hotel-Information) - [Hotel Varinia Serena - Balneario de Alange](https://expedia.co.uk/Alange-Hotels-Hotel-Varinia-Serena-Balneario-De-Alange.h22224741.Hotel-Information) - [Hotel Hacienda Don Manuel](https://expedia.co.uk/Granja-De-Torrehermosa-Hotels-Hotel-Hacienda-Don-Manuel.h105517068.Hotel-Information) [See a list of all hotels in La Serena](https://expedia.co.uk/All-La-Serena-Hotels.d553248635942949504.Travel-Guide-City-All-Hotels) ### More ways to book - 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[Flights from Manchester (MAN) to Minsk (MSQ)](https://expedia.co.uk/lp/flights/man/msq/manchester-to-minsk) - [Flights to Costa Tropical](https://expedia.co.uk/Destinations-In-Costa-Tropical.d3000692293.Flight-Destinations) - [Flights to Swansea](https://expedia.co.uk/Cheap-Flights-To-Swansea.d9958.Travel-Guide-Flights) Cars - [Convertible Car Hire in California](https://expedia.co.uk/Convertible-Car-Rentals-In-California.d206-tConvertible.Car-Rental-Destination-Class) Activities - [Things to do in La Marina Alta](https://expedia.co.uk/Things-To-Do-In-La-Marina-Alta.d553248625840561592.Travel-Guide-Activities) - [Things to do in Villeneuve-Loubet](https://expedia.co.uk/Things-To-Do-In-Villeneuve-Loubet.d5868.Travel-Guide-Activities) Packages - [Cathedral of Milan](https://expedia.co.uk/Cathedral-Of-Milan-Milan-Centre.d501802.Attraction) - [Plaza Mayor](https://expedia.co.uk/Plaza-Mayor-Madrid-Centro.d508457.Attraction) - [La Marina Alta Holidays](https://expedia.co.uk/La-Marina-Alta.d553248625840561592.Holidays-City-Breaks) - [Scheveningen Beach](https://expedia.co.uk/Scheveningen-Beach-Scheveningen.d6064231.Attraction) - [Malacca Holidays](https://expedia.co.uk/Malacca.d6131368.Holidays-City-Breaks) - [Costa Tropical Holidays](https://expedia.co.uk/Costa-Tropical.d3000692293.Holidays-City-Breaks) General - [Visit La Marina Alta](https://expedia.co.uk/La-Marina-Alta.dx553248625840561592) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)