Default HTG hotel image

Find the best La Serena Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

La Serena Accommodation: Most Popular Cities to Stay

A historic church with a bell tower, steps leading up to the entrance, and surrounding trees and parked cars.
HotelsHotels

Castuera

Castuera
A mountainous landscape with a clear sky.
HotelsHotels

Campanario

Campanario

Check prices for these dates

Next weekend
10 Jul - 12 Jul
In two weeks
17 Jul - 19 Jul

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for La Serena hotels

Dining

Casa Rural Casas De Las Regatas

Casa Rural Casas De Las Regatas
2.5 star property
Castuera
Casa Rural Casas De Las Regatas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top La Serena Hotel Reviews

Hotel Sol

Hotel Sol

8/10 Good
"Lovely Spanish small hotel. Great location and friendly and helpful host"
Sarah 1-night trip
Posted 8 days ago
Hotel Sol