Title: Top Hotels in Antofagasta de la Sierra Department - Compare Antofagasta de la Sierra Department Hotels | Expedia.co.uk [Holiday Rentals in Antofagasta de la Sierra Department](https://expedia.co.uk/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Holiday-Rental-Destinations)[Antofagasta de la Sierra Department Car Hire](https://expedia.co.uk/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Car-Hire-Destinations)[Antofagasta de la Sierra Department Holidays](https://expedia.co.uk/Antofagasta-De-La-Sierra-Department.d553248635975749483.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/2/2409417953b688b4a258ccbad0b47836.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Graciela Arena # Find the best Antofagasta de la Sierra Department Hotels ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Antofagasta de la Sierra Department Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/2/bdaecc5a35289f7a555ef5e216022814.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Antofagasta de la Sierra [](https://expedia.co.uk/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Antofagasta de la Sierra Department ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations) ## Top Antofagasta de la Sierra Department Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Antofagasta de la Sierra Department - [Antofagasta de la Sierra Hotels](https://expedia.co.uk/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) - [El Peñón Hotels](https://expedia.co.uk/El-Penon-Hotels.d3000409898.Travel-Guide-Hotels) ### Explore more hotels - [Hacienda de Molinos](https://expedia.co.uk/Molinos-Hotels-Hacienda-De-Molinos.h9028723.Hotel-Information) [See a list of all hotels in Antofagasta de la Sierra Department](https://expedia.co.uk/All-Antofagasta-De-La-Sierra-Department-Hotels.d553248635975749483.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Antofagasta de la Sierra Department on Expedia.com.ar](https://www.expedia.com.ar/Destinos-En-Departamento-Antofagasta-De-La-Sierra.d553248635975749483.Destinos-con-Hoteles) ### Expedia's Latest Trends Hotels - [St. Mellion Estate](https://expedia.co.uk/Saltash-Hotels-St-Mellion-Estate.h2836321.Hotel-Information) - [Newcastle City Hall hotels](https://expedia.co.uk/Newcastle-City-Hall-Hotels.0-l553248635998020255-0.Travel-Guide-Filter-Hotels) - 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