Title: Top Hotels in Antofagasta de la Sierra Department - Compare Antofagasta de la Sierra Department Hotels | Expedia.co.uk [Holiday Rentals in Antofagasta de la Sierra Department](https://expedia.co.uk/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Holiday-Rental-Destinations)[Antofagasta de la Sierra Department Car Hire](https://expedia.co.uk/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Car-Hire-Destinations)[Antofagasta de la Sierra Department Holidays](https://expedia.co.uk/Antofagasta-De-La-Sierra-Department.d553248635975749483.Holidays-City-Breaks) ![Salar or Salt Desert of Antofalla in La Puna de Atacama, in the province of Catamarca in the department of Antofagasta de la Sierra. Argentina, South America, America](https://images.trvl-media.com/place/553248635975749483/23517b45-75d9-415f-936e-1a8925f481d0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best Antofagasta de la Sierra Department Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Antofagasta de la Sierra Department Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/2/bdaecc5a35289f7a555ef5e216022814.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Antofagasta de la Sierra [](https://expedia.co.uk/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) ## Check prices for these dates Tonight [30 Nov - 1 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-11-30&endDate=2025-12-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Dec - 2 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-12-01&endDate=2025-12-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749483&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Antofagasta de la Sierra Department ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248635975749483) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations) ## Top Antofagasta de la Sierra Department Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Antofagasta de la Sierra Department - [Antofagasta de la Sierra Hotels](https://expedia.co.uk/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) - [El Peñón Hotels](https://expedia.co.uk/El-Penon-Hotels.d3000409898.Travel-Guide-Hotels) ### Explore more hotels - [Hacienda de Molinos](https://expedia.co.uk/Molinos-Hotels-Hacienda-De-Molinos.h9028723.Hotel-Information) [See a list of all hotels in Antofagasta de la Sierra Department](https://expedia.co.uk/All-Antofagasta-De-La-Sierra-Department-Hotels.d553248635975749483.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Antofagasta de la Sierra Department on Expedia.com.ar](https://www.expedia.com.ar/Destinos-En-Departamento-Antofagasta-De-La-Sierra.d553248635975749483.Destinos-con-Hoteles) ### Expedia's Latest Trends Hotels - [St. Mellion Estate](https://expedia.co.uk/Saltash-Hotels-St-Mellion-Estate.h2836321.Hotel-Information) - [Hotels near Newcastle City Hall](https://expedia.co.uk/Newcastle-City-Hall-Hotels.0-l553248635998020255-0.Travel-Guide-Filter-Hotels) - [Hamacho Hotel Tokyo Nihonbashi](https://expedia.co.uk/Tokyo-Hotels-HAMACHO-HOTEL-TOKYO-NIHONBASHI.h33511258.Hotel-Information) - [Hotels in Llandrindod Wells](https://expedia.co.uk/Llandrindod-Wells-Hotels.d10088.Travel-Guide-Hotels) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)