A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.

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Check prices for these dates

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

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Our top choices for De Soto hotels

1. Scenic Valley Motel

Scenic Valley Motel
Lansing
United States
Jill
£64
includes taxes & fees
2 Nov - 3 Nov
Scenic Valley Motel

2. Boarders Inn & Suites by Cobblestone Hotels – Waukon

Boarders Inn & Suites by Cobblestone Hotels – Waukon
Waukon
United States
Michael
£75
includes taxes & fees
18 Oct - 19 Oct
Boarders Inn & Suites by Cobblestone Hotels – Waukon

3. AmericInn by Wyndham Viroqua

AmericInn by Wyndham Viroqua
Viroqua
United States
JOSE
£77
includes taxes & fees
18 Oct - 19 Oct
AmericInn by Wyndham Viroqua

4. Sportsmen Motel

Sportsmen Motel
Dorchester
United States
Colin
£71
includes taxes & fees
18 Oct - 19 Oct
Sportsmen Motel

5. MIDWAY MOTEL

MIDWAY MOTEL
Viroqua
United States
Robert
£84
includes taxes & fees
18 Oct - 19 Oct
MIDWAY MOTEL

6. Gundersen Hotel & Suites

Gundersen Hotel & Suites
Powell-Poage-Hamilton
United States
Nicolas
£69
includes taxes & fees
8 Nov - 9 Nov
Gundersen Hotel & Suites

7. Tobacco Warehouse Inn

Tobacco Warehouse Inn
Soldiers Grove
United States
Shelly
£171
includes taxes & fees
19 Oct - 20 Oct
Tobacco Warehouse Inn

8. Welch Motel

Welch Motel
La Crosse
United States
Samuel
£47
includes taxes & fees
8 Nov - 9 Nov
Welch Motel
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Learn more about De Soto

Perched along the Mississippi River, De Soto offers scenic overlooks where bald eagles soar above the water during migration seasons. Explore the nearby Blackhawk Park for fishing and camping, or time your visit for the annual Labour Day celebration with its small-town parade and festivities.

See all hotels in De Soto
A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.

Top De Soto Hotel Reviews

Gundersen Hotel & Suites

Gundersen Hotel & Suites

8/10 Good
"The property and hotel are overall clean and nice. The cloth chairs in the eating area and our room needed to be cleaned, but everything else was clean. The bed was very firm, so if you are like us and prefer a softer bed, you would be uncomfotable."
Heidi 1-night trip
Posted 20 hours ago
Gundersen Hotel & Suites
AmericInn by Wyndham Viroqua

AmericInn by Wyndham Viroqua

10/10 Excellent
"Room was spacious and clean. Bed was amazing and staff was always friendly and helpful. Would definitely stay here again."
Kathy 1-night trip
Posted 21 hours ago
AmericInn by Wyndham Viroqua
NEWLY REMODELED HOME!  INDOOR FISH & GAME CLEANING STATION!

NEWLY REMODELED HOME! INDOOR FISH & GAME CLEANING STATION!

10/10 Excellent
"I would definitely go to this property again. Small group of fisherman with 1 boat. The house is clean and well set up. Easy quiet location and walking distance to a localBar/eatery. Owner was responsive and easy to communicate with."
Jesse S. 3-night trip
Posted 2 days ago
NEWLY REMODELED HOME! INDOOR FISH & GAME CLEANING STATION!
 Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

8/10 Good
"GREAT TIME"
Henrik N. 3-night trip
Posted 4 days ago
Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!
Cozy 3-bedroom farmhouse in gorgeous La Farge with AC

Cozy 3-bedroom farmhouse in gorgeous La Farge with AC

10/10 Excellent
"Very nice property clean secluded and well equipped."
Ela S. 3-night trip
Posted 6 days ago
Cozy 3-bedroom farmhouse in gorgeous La Farge with AC
Scenic Valley Motel

Scenic Valley Motel

8/10 Good
"Room was clean and just right for the one night."
Jill 1-night trip
Posted 7 days ago
Scenic Valley Motel
Log Cabin next to the Mississippi River

Log Cabin next to the Mississippi River

10/10 Excellent
"I just loved the nostalgic somewhat western way it was decorated. I've stayed in many condos since 2002. None even came close to being to having all the utensils etc as this one. On top of that there were other things you would never expect like sandwich bags sugar ice in the ice trays and on and on. Very unique setting outside- you'd have to see it to know its like noother."
Clayton C. 2-night trip
Posted 3 weeks ago
Log Cabin next to the Mississippi River
White Pine Cabin With Swimming Pond & Hot Tub Jacuzzi

White Pine Cabin With Swimming Pond & Hot Tub Jacuzzi

10/10 Excellent
"Great, roomy property in a great location, with an affordable price. 4 separate bedrooms. Enjoyed the stay."
Clark F. 2-night trip
Posted 3 weeks ago
White Pine Cabin With Swimming Pond & Hot Tub Jacuzzi
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

8/10 Good
"Honestly wasn't my choice in cabins, an hour SW of where I was looking. Other VRBOs were snatched up within a few hours (8 to be exact) so I was desperate for a spot for my family with two young adult children. Both recliners were broken, not able to to use for a single sleeping arrangement. There is no stove and the toaster oven was broken but still out on the small kitchenette counter. We made do but my son slept poorly on wide defunct recliner. Host was nice and personable. Probably won't return for various reasons."
Brandon N. 2-night trip
Posted 3 weeks ago
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

More cheap stays in De Soto

Welch Motel

Welch Motel

3643 Mormon Coulee Rd. La Crosse WI
£47
8 Nov - 9 Nov
includes taxes & fees
7.2/10 Good! (334 reviews)
Welch Motel
Scenic Valley Motel

Scenic Valley Motel

1608 Main St Lansing IA
£64
2 Nov - 3 Nov
includes taxes & fees
8.2/10 Very good! (150 reviews)
Scenic Valley Motel
Gundersen Hotel & Suites

Gundersen Hotel & Suites

1520 Clinic Court La Crosse WI
£69
8 Nov - 9 Nov
includes taxes & fees
9.2/10 Wonderful! (1,002 reviews)
Gundersen Hotel & Suites
Sportsmen Motel

Sportsmen Motel

2753 Iowa 76 Dorchester IA
£71
18 Oct - 19 Oct
includes taxes & fees
8.8/10 Excellent! (72 reviews)
Sportsmen Motel
MIDWAY MOTEL

MIDWAY MOTEL

850 N Main St Viroqua WI
£84
18 Oct - 19 Oct
includes taxes & fees
MIDWAY MOTEL
Adriatic

Adriatic

3438 Mormon Coulee Rd La Crosse WI
Get ratesAdriatic

Frequently asked questions

What is the best area to stay in De Soto?
The best area to stay in De Soto is generally near the village centre, particularly along Main Street and its immediate surroundings.This area provides easy access to the Mississippi River and the small collection of local businesses. Main Street, also known as Highway 35, runs directly through the village, making navigation straightforward. You'll find a few local eateries and shops within a short walk.For couples looking for a relaxed getaway, staying close to the riverfront offers pleasant views and easy access to outdoor activities like fishing or birdwatching. The quiet nature of the village centre allows for a peaceful retreat.Families will appreciate the convenience of being near local amenities, which simplifies meal times and access to any essentials.
What are the most romantic hotels in De Soto for couples?
For a romantic stay in De Soto, consider The River View Lodge Sun Set Views over Looking Mississippi River Romantic.This lodge, boasting a great 10.0 review rating, offers a truly intimate experience for couples. You will find a kitchen, a deck or patio, and a porch or lanai, ideal for enjoying the tranquil surroundings. Many guests appreciate the hot tub, the private balcony, and the cosy fireplace, great for relaxing evenings together. The lodge also provides lovely views over the Mississippi River.
What are the best hotels in De Soto near Mississippi River?
For an excellent hotel in De Soto near the Mississippi River, consider The River View Lodge Sun Set Views over Looking Mississippi River Romantic.This highly-rated lodge, boasting a superb 10.0 review score, offers a wonderful stay with a kitchen, a deck or patio, a porch or lanai, and a balcony, superb for enjoying the views. It is located just 430.2 kilometres from the Mississippi River, providing convenient access to the area.
When is the best time to go to De Soto?
The best time to visit De Soto is during the summer months, from June to August, when the weather is warm and pleasant, and the area truly comes alive.This period offers ideal conditions for enjoying the Mississippi River, which is the heart of De Soto's appeal. You'll find plenty of opportunities for boating, fishing, and kayaking. Many local businesses, especially those suiting tourists, are fully operational, offering extended hours and a wider range of services.For those who appreciate fewer crowds and cooler temperatures, late spring (May) and early autumn (September to early October) are also excellent choices. The landscape transforms with vibrant colours in the autumn, making it a particularly scenic time for drives along the Great River Road.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in De Soto.
How much is the nightly rate at a De Soto hotel?
Prices for hotels in De Soto often vary, but you can find a great deal from £47 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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