Barrio de Guadalupe Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £335 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your De Guadalupe Holiday

Your next great adventure is calling your name with a holiday package to De Guadalupe. Food, fun and nonstop great times — you're sure to find it in this neighbourhood. Some leading nearby attractions to visit during your trip to De Guadalupe include San Cristóbal de las Casas Cathedral, Guadalupe Church and Santo Domingo Handicraft Market. Expedia is here to help put your travel plans into action. Book your dream De Guadalupe holiday today.

Where to stay in Barrio de Guadalupe

Find the best Barrio de Guadalupe areas and neighborhoods for the activities you enjoy most. Learn more about Barrio de Guadalupe
The interior of this place is so perfect as soon as someone came into the room they said wow. #culture #design #room #interiordesign #traditional #mexican

Zona Centro

3 out of top 10 points of interest in this area

Unique features of Zona Centro include the museums and gardens. Make a stop by Plaza 31 de Marzo or Mesoamerican Museum of Jade while you're exploring the area.

Find hotels in Zona Centro

Top hotels in Barrio de Guadalupe

Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Cielo y Selva, San Cristobal de las Casas

3 out of 5
Francisco I Madero #94 San Cristóbal de las Casas CHIS
Fully refundableReserve now, pay when you stay
The price is £34 per night from 11 Feb to 12 Feb
£34
11 Feb - 12 Feb
includes taxes & fees
8.4/10 Very Good! (117 reviews)
The staff was very friendly and helpful all the time!

Reviewed on 1 Dec 2025

Hotel Cielo y Selva, San Cristobal de las Casas
Casavieja

Casavieja

4 out of 5
Calle Ma. Adelina Flores #27 San Cristóbal de las Casas CHIS
8.6/10 Excellent! (337 reviews)
Great location and very kind staff! Our room was on the 3rd floor super gorgeous view of the town and very central to everything! Would stay again for sure!

Reviewed on 4 Jan 2026

Get rates
Casavieja
Hotel Tepeyac

Hotel Tepeyac

3 out of 5
Andador Guadalupe No. 40 San Cristóbal de las Casas CHIS
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (142 reviews)
Clean room, good staff

Reviewed on 22 Dec 2025

Get rates
Hotel Tepeyac
See all 305 properties in Barrio de Guadalupe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a De Guadalupe travel package cost?
Custom make your De Guadalupe package from just . Choose from any combination of flights, hotels and rental cars to pull together the escape you've been dreaming about for ages. Be sure to add on a few activities!
If I'm not able to travel, can I cancel my De Guadalupe travel package?
You sure can, and we're here to help. You may be able to cancel and rebook your De Guadalupe travel package for free if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company for older bookings. If life gets in the way of your holiday, have a look at our Customer Service Portal for more information.
How do I get a cheap travel package to De Guadalupe?
Book everything in one place with our De Guadalupe travel packages. You'll discover deals on flights, hotels and more that'll keep your pocketbook happy and your adventurous spirit busy. And, with more than 550 partner airlines and 1,000,000 hotel options throughout the world to pick from, there are endless opportunities to mix and match as you please.
Does Expedia offer Book Now, Pay Later De Guadalupe holidays?
Expedia has teamed up with online lender Klarna to make booking your next getaway easier on your bank balance. Paying by instalment means you can spread the costs of your next big adventure, leaving you with more cash to spend while you're travelling. Klarna has several payment plans to pick from, so you're sure to find something that fits into your budget. Consider these flexible payment options:

  • Pay monthly holidays: Realise your holiday dreams sooner with Klarna's convenient monthly instalment plans. If paying a little each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Hitting the "book now" button is easier with this payment plan. Simply put down a small deposit on your escape and then start packing your bags.

Where should I stay in De Guadalupe?
A trip to De Guadalupe isn't complete without paying a visit to San Cristóbal de las Casas Cathedral, Na Bolom Cultural Museum and Guadalupe Church. Spend your nights near these top attractions and make sightseeing a breeze.
What are the top hotels in De Guadalupe?
Make a reservation at Hotel Sombra del Agua. It's one of the area's most popular hotels. Another top-rated option in De Guadalupe is Docecuartos Hotel.
How far in advance should I book my De Guadalupe holiday?
While prices change from time to time, we generally suggest booking your holiday as early as possible. Most international fares can be compared on Expedia up to a year in advance. If you're booking late, you may still get lucky. Discount prices to De Guadalupe occasionally appear only weeks before departure.
What does an Expedia De Guadalupe travel package include?
With Expedia, you can choose any combination of flights, car rentals and hotels to create your ideal De Guadalupe package. Once you've made your booking, you can add on the fun stuff like tours and activities. Remember, the more you bundle, the more dollars you'll save!
What should I know before booking a De Guadalupe travel package?
Whether it's adventure or relaxation you're craving, a De Guadalupe travel package lets you organise your escape your way. Plus, you'll get access to great discounts just for combining your hotel with your rental car and flights. The more you bundle, the more you'll save!
Can I choose my airline with a De Guadalupe Expedia travel package?
You can, and with more than 550 airlines to select from across the globe, you've got lots of choice. Search the available options and find out which airline fits your budget and needs.

Popular places to visit

Guadalupe Church showing heritage elements

Guadalupe Church

4/5(1 review)

Climb the 79 steps to appreciate the staggering views from this hilltop church. The church itself is a pretty example of colonial architecture.

Guadalupe Church
Na Bolom Cultural Museum as well as a couple

Na Bolom Cultural Museum

Tour this remarkable museum and cultural center, which depicts the lifetime of study of the Lacandón indigenous people by Gertrude Duby and Frans Blom.

Na Bolom Cultural Museum
Orquideas Moxviduil Botanical Garden showing forests

Orquídeas Moxviquil Botanical Garden

5/5(1 review)

Be enchanted by this beautiful botanical garden, which rescues, protects and conserves orchids and other native plants of the Chiapas region.

Orquídeas Moxviquil Botanical Garden

Things to do

Church of San Juan Chamula

San Juan Chamula and Zinacantán Indigenous Communities

£15
per adult
San Juan Chamula and Zinacantán Indigenous Communities
Rancho Nuevo Caves and Arcotete Ecotourism Center

Rancho Nuevo Caves and Arcotete Ecotourism Center

£17
per adult
Rancho Nuevo Caves and Arcotete Ecotourism Center
From San Cristobal: Zinacantán and San Juan Chamula Tour

FromSan Cristobal:Zinacantán andSanJuanChamula ENGLISH GUIDE

£22
per adult
FromSan Cristobal:Zinacantán andSanJuanChamula ENGLISH GUIDE
See all activities in San Cristóbal de las Casas

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.