Title: Cheap Car Hire in Santa María, PRY - Expedia.co.uk [Santa María Travel Guide](https://expedia.co.uk/Santa-Maria.dx553248635975867967)[Hotels in Santa María](https://expedia.co.uk/Santa-Maria-Hotels.d553248635975867967.Travel-Guide-Hotels)[Flights to Santa María](https://expedia.co.uk/Cheap-Flights-To-Santa-Maria.d553248635975867967.Travel-Guide-Flights)[Santa María Holidays](https://expedia.co.uk/Santa-Maria.d553248635975867967.Holidays-City-Breaks) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Santa María, PRY ## Search and Compare from Car Companies in Santa María ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Santa María \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Santa María, Itapúa Department, PRY ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Mar%C3%ADa,%20Encarnacion,%20Itap%C3%BAa%20Department,%20Paraguay&dpln=553248635975867967&date1=18/02/2026&date2=20/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Santa María, Itapúa Department, PRY ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Mar%C3%ADa,%20Encarnacion,%20Itap%C3%BAa%20Department,%20Paraguay&dpln=553248635975867967&date1=18/02/2026&date2=20/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Santa María, Itapúa Department, PRY ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Mar%C3%ADa,%20Encarnacion,%20Itap%C3%BAa%20Department,%20Paraguay&dpln=553248635975867967&date1=18/02/2026&date2=20/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Santa María, Itapúa Department, PRY ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Mar%C3%ADa,%20Encarnacion,%20Itap%C3%BAa%20Department,%20Paraguay&dpln=553248635975867967&date1=18/02/2026&date2=20/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Santa María [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Mar%C3%ADa,%20Encarnacion,%20Itap%C3%BAa%20Department,%20Paraguay&dpln=553248635975867967&date1=18/02/2026&date2=20/02/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=CTG_SPRING_PROMO_553248635975867967) ## Frequently asked questions ### How much is a rental car per day in Santa María? ### What happens if I need to cancel my Santa María car reservation? ### What types of cars can I rent in Santa María? ### How do I find the best car hire deals in Santa María with Expedia? ### What do you need to hire a car in Santa María? ### What is the cheapest car hire in Santa María? ### Can I hire a car for a month or longer in Santa María? ### Where can I find a Santa María hire car if I am younger than 25? ### Why should I rent a Santa María car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app