Car Rentals in Santa Fe, PAN

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Top Rental Car Deals in Santa Fe

* Price found within the past 6 days. Click for updated prices.

Economy

Chevrolet Spark or similar
  • 4 people
Santa Fe, Darién Province, PAN
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Santa Fe, Darién Province, PAN
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Santa Fe, Darién Province, PAN
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Santa Fe, Darién Province, PAN
Jeep Compass
SUV Jeep Compass

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Frequently asked questions

How much is a rental car per day in Santa Fe?
Car hire in Santa Fe had a low daily rate of just within the past seven days. With prices this good, you'll be zooming around in a snazzy ride with money to spare.
What happens if I need to cancel my Santa Fe car reservation?
When you cancel at least six hours in advance of collecting the car, the majority of prepaid reservations qualify for a total refund. However, not all are eligible for this, so it's important to read your rental agreement. Look over your confirmation for the specifics or visit our Customer Service Portal to find out more.
What types of cars can I rent in Santa Fe?
If you'll be visiting bustling cities, it's better to think small — like an economy-sized car. The most booked type of hire in Santa Fe, they can easily navigate traffic-filled streets, squeeze into narrow parking spaces and offer fantastic mileage. But there's nothing holding you back from going big either! Browse our standard or full-size options if you want some extra space, or take things up a notch with one of our stylish premium rides.
Where can I go on a road trip from Santa Fe?
Book some wheels, grab the keys and discover all the sights and sounds of Santa Fe. But with tons of places to see in the surrounding areas, that shouldn't be the end of the road! Set your sat-nav to some of the other inspiring places in the region:

  • You'll feel the vibrant spirit of a city bursting with life the second you pull into San Miguelito. Some 95 miles from Santa Fe, it's home to a ton of wonderful places to discover, like Metromall Panama.
  • Chepo, around 75 miles away, also promises a good time. Wondering what there is to see? San Cristobal Church is our top pick.
  • Get away from city life at Venao Beach. Approximately 160 miles from Santa Fe, it's the perfect place to get your nature fix.

How do I find the best car hire deals in Santa Fe with Expedia?
Finding the best deal on your Santa Fe hire car is a piece of cake with Expedia. Choose your preferred car class, add some details and compare prices across popular brands. Why not add hotels and flights to your booking? You'll score even more savings when you create a holiday package.
What do you need to rent a car in Santa Fe?
While terms and conditions can differ between car rental outlets, the essentials are a valid driver's license and a credit card in your name. You don't need to take out auto insurance with your rental provider. However, proof of your own coverage may be required.
What is the cheapest car hire in Santa Fe?
The lowest hire car price in Santa Fe within the past seven days was just per day. The next best deal was . These rates were available on Expedia, with a rental starting date within the next year. Prices and availability are subject to change and additional terms apply.
Can I hire a car for a month or longer in Santa Fe?
Expedia makes it a breeze to pick up an affordable long-term rental in Santa Fe. Just visit our long-term car rental deals page, enter your travel dates and compare your choices.
Where can I find a Santa Fe hire car if I am younger than 25?
Some Santa Fe companies will rent cars to drivers under 25, and others won't. Age policies differ between suppliers, so you'll need to do some research. Also, find out if there are extra costs. Some places will pass on a surcharge to young customers between 21 and 24. Always read through the terms and conditions to avoid any surprise fees.
Why should I rent a Santa Fe car with Expedia?
With loads of experience finding the lowest prices for travellers across the globe, Expedia is a great place to hire your vehicle. We have multiple suppliers in Santa Fe to take your pick of, offering everything from small economy rides to full-size SUVs. Why not bundle your car with your flights and hotel and save more? From our holiday packages to our member prices and exclusive offers, Expedia will get you on your way for less. Plus, when you're a member of our One Key™ loyalty programme, you can collect OneKeyCash™* and use it on eligible flights, activities, hotels and more. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Expedia.

Car Hire Information

Popular car types:
SUV, Full Size, Economy
Car suppliers available:
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From the airport to your hotel:
Airport Transportation