Title: Cheap Car Hire in San Diego, COL - Expedia.co.uk [San Diego Travel Guide](https://expedia.co.uk/Medellin-San-Diego.dx6323725)[Hotels in San Diego](https://expedia.co.uk/San-Diego-Medellin-Hotels.0-n6323725-0.Travel-Guide-Filter-Hotels)[Flights to Medellin](https://expedia.co.uk/Cheap-Flights-To-Medellin.d2246.Travel-Guide-Flights)[Things to do in Medellin](https://expedia.co.uk/Things-To-Do-In-Medellin.d2246.Travel-Guide-Activities)[San Diego Holidays](https://expedia.co.uk/San-Diego.d6323725.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6323725/982d92f9-33bb-4133-ae19-383b87d9aa44.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in San Diego, COL ## Search and Compare from Car Companies in San Diego ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in San Diego \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Medellin, Antioquia, COL ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=San%20Diego,%20Medell%C3%ADn,%20Antioquia,%20Colombia&dpln=6323725&date1=27/02/2026&date2=01/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Medellin, Antioquia, COL ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=San%20Diego,%20Medell%C3%ADn,%20Antioquia,%20Colombia&dpln=6323725&date1=27/02/2026&date2=01/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Medellin, Antioquia, COL ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=San%20Diego,%20Medell%C3%ADn,%20Antioquia,%20Colombia&dpln=6323725&date1=27/02/2026&date2=01/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Medellin, Antioquia, COL ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=San%20Diego,%20Medell%C3%ADn,%20Antioquia,%20Colombia&dpln=6323725&date1=27/02/2026&date2=01/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in San Diego [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=San%20Diego,%20Medell%C3%ADn,%20Antioquia,%20Colombia&dpln=6323725&date1=27/02/2026&date2=01/03/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=CTG_SPRING_PROMO_6323725) ## Frequently asked questions ### How much is a rental car per day in San Diego? ### Can I hire a car from Jose Maria Cordova Intl. Airport (MDE)? ### What happens if I need to cancel my San Diego car reservation? ### What types of cars can I rent in San Diego? ### Where can I go on a road trip from San Diego? > - Home to sights and experiences galore, Santa Rosa de Cabal is approximately 95 miles from San Diego. First pit stop? Make your way to Santa Rosa de Cabal Hot Springs, one of the city's biggest highlights. > - Pereira, around 100 miles away, also promises a good time. Curious what there is to see? Ukumari Zoo is our top pick. > - No holiday is complete without taking in Monserrate. This delightful nature spot is roughly 150 miles from San Diego. Relax and breathe in the fresh air! ### How do I find the best car hire deals in San Diego with Expedia? ### How old do you have to be to rent a car in San Diego? ### What do you need to hire a car in San Diego? ### What is the cheapest car rental in San Diego? ### Can I hire a car for a month or longer in San Diego? ### Where can I find a San Diego hire car if I am younger than 25? ### Why should I rent a San Diego car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) |