Cherokee Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your Cherokee Holiday

Our holiday packages to Cherokee allow you to create your own adventure. Tailor your journey to suit your interests and needs and make the most of your time in this exciting city. If taking in sights is on the to-do list during your trip to Cherokee, stop by major attractions like East Tennessee State University, Freedom Hall Civic Centre and Johnson City Mall. No matter your travel plans or budget, organising your ultimate tailored Cherokee holiday is a piece of cake with Expedia.

Cherokee Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Tri-Cities Regional Airport (TRI)
Max Temp Winter
7ºC
Max Temp Summer
29ºC
Top Sights
Grey Fossil Museum, Yee-Haw Brewing Company and Wallabies

Top hotels in Cherokee

Carnegie Hotel & Spa

Carnegie Hotel & Spa

4 out of 5
1216 W State Of Franklin Rd Johnson City TN
Fully refundableReserve now, pay when you stay
The price is £132 per night from 31 May to 1 Jun
£132
31 May - 1 Jun
includes taxes & fees
9.8/10 Exceptional! (1,411 reviews)
"Dinner was delicious. Breakfast was fairly priced and the yogurt with berries and homemade granola was the best!"

Reviewed on 20 May 2026

Carnegie Hotel & Spa
Sleep Inn & Suites Johnson City

Sleep Inn & Suites Johnson City

2.5 out of 5
2020 Franklin Terrace Court Johnson City TN
Fully refundableReserve now, pay when you stay
The price is £74 per night from 24 May to 25 May
£74
24 May - 25 May
includes taxes & fees
8.4/10 Very Good! (931 reviews)
"Very clean. Staff is very nice."

Reviewed on 21 May 2026

Sleep Inn & Suites Johnson City
Echo Suites Extended Stay By Wyndham Johnson City Medical Cr

Echo Suites Extended Stay By Wyndham Johnson City Medical Cr

2 out of 5
1100 Clinchfield Street Johnson City TN
Fully refundableReserve now, pay when you stay
The price is £73 per night from 28 May to 29 May
£73
28 May - 29 May
includes taxes & fees
8.8/10 Excellent! (301 reviews)
"I like the hotel but it is pretty basic. I miss having a coffee pot in the room or at least extend coffee in the lobby until 10am. But it is very clean and all the staff has been very friendly. Also very convenient to stores and restaurants."

Reviewed on 19 May 2026

Echo Suites Extended Stay By Wyndham Johnson City Medical Cr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.