Title: Cheap Flights to Santana - Expedia.co.uk

![](https://images.trvl-media.com/place/553248635974903086/d35e79ad-6d17-4482-90bd-71db9c6c2017.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Fabrice Récalt

![](https://images.trvl-media.com/place/553248635974903086/d35e79ad-6d17-4482-90bd-71db9c6c2017.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# £161 Cheap Flights to Santana

[View £161 flight on Thu, 21 May 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:LBV,to:TMS,departure:21/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:160.80&airProductToken=AQovCi0Iy6ABEgI2MBirqAEgk5MBKMjLjQMwhMyNAzhUQABYAWoCUFJyB1RQUk9XMVASCggBEAEYASoCS1AYASIECAEQASgCKAMoBDAB) 

[Hotels in Santana](https://expedia.co.uk/Santana-Hotels.d553248635974903086.Travel-Guide-Hotels)[Santana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santana.d553248635974903086.Car-Hire-Guide)[Santana Holidays](https://expedia.co.uk/Santana.d553248635974903086.Holidays-City-Breaks)

## Popular airlines to Santana

- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg)  
TAP Portugal  
[](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santana, Cantagalo, São Tomé and Príncipe,departure:18/04/2026TANYT&leg2=from:Santana, Cantagalo, São Tomé and Príncipe,to:CMH,departure:25/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TP"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_ET.svg)  
Ethiopian Airlines  
[](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santana, Cantagalo, São Tomé and Príncipe,departure:18/04/2026TANYT&leg2=from:Santana, Cantagalo, São Tomé and Príncipe,to:CMH,departure:25/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"ET"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KP.svg)  
ASKY  
[](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santana, Cantagalo, São Tomé and Príncipe,departure:18/04/2026TANYT&leg2=from:Santana, Cantagalo, São Tomé and Príncipe,to:CMH,departure:25/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KP"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DT.svg)  
TAAG Angola Airlines  
[](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santana, Cantagalo, São Tomé and Príncipe,departure:18/04/2026TANYT&leg2=from:Santana, Cantagalo, São Tomé and Príncipe,to:CMH,departure:25/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DT"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_H1.svg)  
Hahn Air Systems  
[](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santana, Cantagalo, São Tomé and Príncipe,departure:18/04/2026TANYT&leg2=from:Santana, Cantagalo, São Tomé and Príncipe,to:CMH,departure:25/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"H1"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/03/25/landing_airline_sq_logo_A1.svg)  
APG Distribution System  
[](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santana, Cantagalo, São Tomé and Príncipe,departure:18/04/2026TANYT&leg2=from:Santana, Cantagalo, São Tomé and Príncipe,to:CMH,departure:25/04/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"A1"}}])

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## Cheap round-trip flights to Santana

Prices were available within the past 7 days and start at £161 for one-way flights and £289 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Return

![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif)

Wed, 3 Jun - Fri, 12 Jun

ACC

Accra

TMS

São Tomé Island

£289

Return

found 3 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:ACC,to:TMS,departure:03/06/2026TANYT&leg2=from:TMS,to:ACC,departure:12/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:288.30&airProductToken=AQo2CjQI1KABEgQxNTI3GMAQIJOTASi73Y4DMKnejgM4VEAAWAFqB0RJU0NJTlRyCFRMMERTSTgwCjYKNAjUoAESBDE1MjgYk5MBIMAQKLzEjwMwm8WPAzhUQABYAWoHRElTQ0lOVHIIVEwwRFNJODASCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN)

![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif)

Thu, 17 Sept - Sun, 20 Sept

LBV

Libreville

TMS

São Tomé Island

£304

Return

found 1 day ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LBV,to:TMS,departure:17/09/2026TANYT&leg2=from:TMS,to:LBV,departure:20/09/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:303.88&airProductToken=AQovCi0Iy6ABEgI2MBirqAEgk5MBKKiGmAMw5IaYAzhUQABYAWoCUFJyB1RQUjFNMVAKLwotCMugARICNjEYk5MBIKuoASjEo5gDMICkmAM4VEAAWAFqAlBScgdUUFIxTTFQEgoIARABGAEqAktQGAEiBAgBEAEoAigDKAQwAQ)

![Hahn Air Systems](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/h1.gif)

Sun, 17 May - Sun, 24 May

LBV

Libreville

TMS

São Tomé Island

£343

Return

found 23 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LBV,to:TMS,departure:17/05/2026TANYT&leg2=from:TMS,to:LBV,departure:24/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:342.10&airProductToken=AQo1CjMIyGISBDYzMDMYq6gBIJOTASiTmo0DMM-ajQM4TUAAWAFyBU1PV0o3egkIym4SBDYzMDMSCggBEAEYASoCSFIYASIECAEQASgCKAMoBDAB)

![World Ticket Ltd](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/w1.gif)

Tue, 21 Apr - Sun, 26 Apr

LBV

Libreville

TMS

São Tomé Island

£979

Return

found 5 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LBV,to:TMS,departure:21/04/2026TANYT&leg2=from:TMS,to:LBV,departure:26/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:978.80&airProductToken=AQo2CjQI12ISAzEyMBirqAEgk5MBKMP3igMw__eKAzhNQABYAXIITUo3QkFTSUN6CAjKbhIDMTIwEgoIARABGAEqAlcyGAEiBAgBEAEoAigDKAQwAQ)

![Air Serbia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/JU.gif)

Sat, 5 Sept - Wed, 16 Sept

BEG

Belgrade

TMS

São Tomé Island

£1,197

Return

found 2 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BEG,to:TMS,departure:05/09/2026TANYT&leg2=from:TMS,to:BEG,departure:16/09/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1197.00&airProductToken=AQqaAQowCMqqARIDMzMwGIExILk8KOL5lgMw0PqWAzhWQABYAWoFQkFTSUNyCFVGMEJTSTBDCjEI1KABEgM5MzMYuTwgi5IBKIX_lgMwuYCXAzhVQAFYAWoFQkFTSUNyCFVGMEJTSTBDCjMI1KABEgQxNTI3GIuSASCTkwEo94aXAzCJi5cDOFVAAVgBagVCQVNJQ3IIVUYwQlNJMEMKmgEKMwjUoAESBDE1MjgYk5MBIIuSASi8_JcDMMSAmAM4VUAAWAFqBUJBU0lDcghVRjBCU0kwQwoxCNSgARIDNTcwGIuSASClBCj4gZgDMLaDmAM4VUABWAFqBUJBU0lDcghVRjBCU0kwQwowCMqqARIDMzUzGKUEIIExKIyHmAMwhIiYAzhVQAFYAWoFQkFTSUNyCFVGMEJTSTBDEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ)

## Book with confidence

# Expedia flights to Santana

Searching for cheap flights to Santana? No travel company presents more choices than Expedia if you're looking to compare flights to Santana. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Cantagalo. Expedia provides the cheapest flights to many destinations in Cantagalo and you may find even greater savings if you combine your flight with a hotel stay in Santana.

Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast.

Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Santana for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Santana flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price.

## Travel information

| Destination airport           | São Tomé Intl.  |
| ----------------------------- | --------------- |
| Destination airport IATA code | TMS             |
| Destination city name         | São Tomé Island |
| Return price                  | £288            |

## Trending flights to Santana

Prices were available within the past 7 days and start at £161 for one-way flights and £289 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Return

![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif)

Thu, 12 Nov - Wed, 18 Nov

LGW

London

TMS

São Tomé Island

£834

Return

found 3 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LGW,to:TMS,departure:12/11/2026TANYT&leg2=from:TMS,to:LGW,departure:18/11/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:833.50&airProductToken=AQp6CkEI1KABEgQxMzM3GMuxASCLkgEogPycAzCq_ZwDOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MXoKCM6SARIEMTMzNwo1CNSgARIEMTUyNxiLkgEgk5MBKJ-EnQMwp4idAzhUQABYAWoHRElTQ0lOVHIIVEwwRFNJODEKego1CNSgARIEMTUyOBiTkwEgi5IBKLDBnQMw0cWdAzhUQABYAWoHRElTQ0lOVHIIVEwwRFNJODEKQQjUoAESBDEzMzYYi5IBIMuxASj_yJ0DMKnKnQM4VEAAWAFqB0RJU0NJTlRyCFRMMERTSTgxegoIzpIBEgQxMzM2EgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwDQ)

\*Available to Expedia members.