Title: Cheap Flights to Santa Isabel - Expedia.co.uk ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £47 Cheap Flights to Santa Isabel [View £47 flight on Wed, 4 Mar 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:GYE,to:CUE,departure:04/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:46.90&airProductToken=AQowCi4IzIIBEgQxMzYzGIYmIIIlKPPehgMwot-GAzhPQABYAWoCUVByCE8wMFFQQVpKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Hotels in Santa Isabel](https://expedia.co.uk/Santa-Isabel-Hotels.d6175932.Travel-Guide-Hotels)[Santa Isabel Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Isabel.d6175932.Car-Hire-Guide)[Santa Isabel Holidays](https://expedia.co.uk/Santa-Isabel.d6175932.Holidays-City-Breaks) ## Popular airlines to Santa Isabel - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Isabel, Santa Isabel, Azuay, Ecuador,departure:23/02/2026TANYT&leg2=from:Santa Isabel, Santa Isabel, Azuay, Ecuador,to:CMH,departure:02/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Isabel, Santa Isabel, Azuay, Ecuador,departure:23/02/2026TANYT&leg2=from:Santa Isabel, Santa Isabel, Azuay, Ecuador,to:CMH,departure:02/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Isabel, Santa Isabel, Azuay, Ecuador,departure:23/02/2026TANYT&leg2=from:Santa Isabel, Santa Isabel, Azuay, Ecuador,to:CMH,departure:02/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Isabel, Santa Isabel, Azuay, Ecuador,departure:23/02/2026TANYT&leg2=from:Santa Isabel, Santa Isabel, Azuay, Ecuador,to:CMH,departure:02/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AM.svg) Aeromexico [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Isabel, Santa Isabel, Azuay, Ecuador,departure:23/02/2026TANYT&leg2=from:Santa Isabel, Santa Isabel, Azuay, Ecuador,to:CMH,departure:02/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AM"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to Santa Isabel Prices were available within the past 7 days and start at £47 for one-way flights and £92 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Wed, 4 Mar - Tue, 10 Mar GYE Guayaquil CUE Cuenca £92 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GYE,to:CUE,departure:04/03/2026TANYT&leg2=from:CUE,to:GYE,departure:10/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:91.80&airProductToken=AQowCi4IzIIBEgQxMzYzGIYmIIIlKPPehgMwot-GAzhPQABYAWoCUVByCE8wMFFQQVpKCjAKLgjMggESBDEzNTgYgiUghiYo3qKHAzCKo4cDOE9AAFgBagJRUHIITzAwUVBBWkoSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Thu, 19 Mar - Sun, 22 Mar GYE Guayaquil CUE Cuenca £94 Return found 10 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GYE,to:CUE,departure:19/03/2026TANYT&leg2=from:CUE,to:GYE,departure:22/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:93.60&airProductToken=AQowCi4IzIIBEgQxMzYzGIYmIIIlKLqIiAMw6YiIAzhPQABYAWoCUVByCE8wMFFQQVpKCjAKLgjMggESBDEzNTgYgiUghiYooqeIAzDOp4gDOE9AAFgBagJRUHIITzAwUVBBWkoSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Mon, 1 Jun - Tue, 30 Jun UIO Quito CUE Cuenca £95 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:UIO,to:CUE,departure:01/06/2026TANYT&leg2=from:CUE,to:UIO,departure:30/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:94.80&airProductToken=AQozCjEIwawBEgQxNjA2GJRyIIIlKMzKjgMwiMuOAzhTQABYAWoFQkFTSUNyCFNST0IwSVJJCjMKMQjBrAESBDE2MDcYgiUglHIo2pGRAzCRkpEDOFNAAFgBagVCQVNJQ3IIU1JPQjBJUkkSCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Mon, 16 Mar - Mon, 6 Apr LGW London CUE Cuenca £962 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LGW,to:CUE,departure:16/03/2026TANYT&leg2=from:CUE,to:LGW,departure:06/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:961.83&airProductToken=AQqcAQozCNWwARIEMTAxNhjLsQEgjBgoteWHAzDL5ocDOFpAAFgBaghTVEFOREFSRHIGWllZUlBPCjEI1bABEgMxMzcYjBgglHIo7eiHAzD87YcDOFpAAVgBaghTVEFOREFSRHIGWllZUlBPCjIIwawBEgQxNjA2GJRyIIIlKMzzhwMwiPSHAzhXQAFYAWoIU1RBTkRBUkRyBlpZWVJQTwqcAQoyCMGsARIEMTYwORiCJSCUciiK0YkDMLzRiQM4V0AAWAFqCFNUQU5EQVJEcgZaWVlSUE8KMQjVsAESAzEzOBiUciCMGCjD3IkDMLThiQM4WkABWAFqCFNUQU5EQVJEcgZaWVlSUE8KMwjVsAESBDEwMTUYjBggy7EBKIzmiQMwneeJAzhaQAFYAWoIU1RBTkRBUkRyBlpZWVJQTxIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Fri, 8 May - Thu, 28 May DUB Dublin CUE Cuenca £1,200 Return found 9 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:DUB,to:CUE,departure:08/05/2026TANYT&leg2=from:CUE,to:DUB,departure:28/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1199.30&airProductToken=AQqaAQoyCMuYARIEMTE0MBiDDSCAkwEoqbeMAzCIuIwDOExAAFgBagVMSUdIVHIIUkdMMFRCTEEKMQjLmAESAzc1MRiAkwEglHIoz8CMAzCLxowDOFJAAVgBagVMSUdIVHIIUkdMMFRCTEEKMQjBrAESBDE2MDYYlHIggiUo7MeMAzCoyIwDOFNAAVgBagVMSUdIVHIIUkdMMFRCTEEKmgEKMQjBrAESBDE2MDUYgiUglHIouJiOAzDvmI4DOFNAAFgBagVMSUdIVHIIRUdMMEtCTEEKMQjLmAESAzc1MRiUciCAkwEosZyOAzCDo44DOEVAAVgBagVMSUdIVHIIRUdMMEtCTEEKMgjLmAESBDExNDUYgJMBIIMNKIGnjgMw5aeOAzhMQAFYAWoFTElHSFRyCEVHTDBLQkxBEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwAQ) ## Expedia flights to Santa Isabel Searching for cheap flights to Santa Isabel? No travel company presents more choices than Expedia if you're looking to compare flights to Santa Isabel. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Azuay. Expedia provides the cheapest flights to many destinations in Azuay and you may find even greater savings if you combine your flight with a hotel stay in Santa Isabel. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Santa Isabel for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Santa Isabel flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Frequently asked questions ### What is the name of Santa Isabel's airport? ### What airport is best to fly into Santa Isabel? ### How many airlines fly to Santa Isabel? ### Which airlines fly to Santa Isabel? ### How many nonstop flights are there to Santa Isabel? ### Where are the most popular flights to Santa Isabel departing from? ### How long is the flight to Santa Isabel Airport? ### How to book the cheapest flight to Santa Isabel? ### Do you have any tips for my flight to Santa Isabel? > - The secret to having a hassle-free travel experience is to be prepared. Start with the essentials: passport, official ID, bank cards and any vital medications. Next, bring on board items that'll help while away those hours, like your laptop or a magazine. It's also a wise idea to pack your chargers, a quality neck pillow and a pair of earphones. Finally, don't forget to pop in toiletries like a toothbrush, cleansing wipes and a spare set of clothes. > > > Do not pack the following items in your hand luggage: > > > - Leave all your full-sized bottles of shampoo and hairspray in your checked luggage. Any liquids in your carry-on suitcase larger than 3.4 ounces (100 millilitres) will be confiscated. Sharp or pointed objects, like your pocket knife, and products which are flammable or explosive, such as aerosol cans, spray paint and fuels, are also banned. > > > What to wear on a flight: > > > - Comfort should be your number one priority when deciding what to wear on your flight. Loose, breathable clothing is a wise option, as are enclosed shoes like sneakers. > - Deep vein thrombosis (DVT) is a risk on long-haul flights. It's the result of blood clotting due to poor circulation, so do some gentle foot and leg exercises in your seat and consider wearing compression socks. ### How to get through airport security fast when flying to Santa Isabel? > - First things first. Your passport and boarding pass will need to be inspected by security personnel. Keep them within easy reach to avoid fumbling around for them. > - Time to strip down. Well kind of. Your coat, belt, keys and other contents of your pockets, like coins, will be required to go through the X-ray machine. Make the whole process easier by removing them before your turn arrives. > - Your electronic gadgets like phones and laptops will also need to go on a tray for inspection. No need to worry though, you'll be back online before you know it. > - Any gels or liquids, such as shampoo or hairspray, that you want to take on board need to be in containers no larger than 3.4 ounces (100 millilitres). Also, everything must fit inside a quart-size (one litre), clear zip-close bag. > - The right choice of footwear can save you several precious minutes. Boots and bulky shoes are often required to be removed and X-rayed separately. Lightweight sneakers usually aren't. > - Avoid taking prohibited items in your carry-on bag. If you have any sharp or pointed objects, pack them in your checked baggage. They won't be allowed in the cabin. __Flights to Santa Isabel information__ | Destination airport | Mariscal Lamar | | ----------------------------- | -------------- | | Destination airport IATA code | CUE | | Destination city name | Cuenca | | Return price | £92 | ## Trending flights to Santa Isabel Prices were available within the past 7 days and start at £47 for one-way flights and £92 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Mon, 16 Mar - Mon, 6 Apr LGW London CUE Cuenca £962 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LGW,to:CUE,departure:16/03/2026TANYT&leg2=from:CUE,to:LGW,departure:06/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:961.83&airProductToken=AQqcAQozCNWwARIEMTAxNhjLsQEgjBgoteWHAzDL5ocDOFpAAFgBaghTVEFOREFSRHIGWllZUlBPCjEI1bABEgMxMzcYjBgglHIo7eiHAzD87YcDOFpAAVgBaghTVEFOREFSRHIGWllZUlBPCjIIwawBEgQxNjA2GJRyIIIlKMzzhwMwiPSHAzhXQAFYAWoIU1RBTkRBUkRyBlpZWVJQTwqcAQoyCMGsARIEMTYwORiCJSCUciiK0YkDMLzRiQM4V0AAWAFqCFNUQU5EQVJEcgZaWVlSUE8KMQjVsAESAzEzOBiUciCMGCjD3IkDMLThiQM4WkABWAFqCFNUQU5EQVJEcgZaWVlSUE8KMwjVsAESBDEwMTUYjBggy7EBKIzmiQMwneeJAzhaQAFYAWoIU1RBTkRBUkRyBlpZWVJQTxIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE) \*Available to Expedia members.