Title: Cheap Flights to Santa Cruz - Expedia.co.uk ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £44 Cheap Flights to Santa Cruz [View £44 flight on Sat, 14 Mar 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:BOG,to:MDE,departure:14/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:43.20&airProductToken=AQowCi4IzIIBEgQ0MDM4GMEzIOwgKMnMhwMwhc2HAzhPQABYAWoCUVByCE8wMFFQR1pUEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) [Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d553248635976386952.Travel-Guide-Hotels)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d553248635976386952.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d553248635976386952.Holidays-City-Breaks) ## Popular airlines - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_NK.svg) Spirit Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"NK"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_B6.svg) JetBlue Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Santa Cruz, Medellín, Antioquia, Colombia,departure:12/03/2026TANYT&leg2=from:Santa Cruz, Medellín, Antioquia, Colombia,to:CMH,departure:19/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to Santa Cruz Prices were available within the past 7 days and start at £44 for one-way flights and £87 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Sat, 14 Mar - Mon, 16 Mar BOG Bogotá MDE Medellin £87 Return just found [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BOG,to:MDE,departure:14/03/2026TANYT&leg2=from:MDE,to:BOG,departure:16/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:86.70&airProductToken=AQowCi4IzIIBEgQ0MDE4GMEzIOwgKJHOhwMwzc6HAzhPQABYAWoCUVByCE8wMFFQR1pUCjAKLgjMggESBDQwMDMY7CAgwTMoluKHAzDX4ocDOE9AAFgBagJRUHIITzAwUVBHWlQSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Mon, 6 Apr - Mon, 13 Apr BOG Bogotá MDE Medellin £100 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BOG,to:MDE,departure:06/04/2026TANYT&leg2=from:MDE,to:BOG,departure:13/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:99.10&airProductToken=AQozCjEIwawBEgQ5MzAyGMEzIOwgKNPQiQMwitGJAzhTQABYAWoFQkFTSUNyCFNFT0IwSVJLCjMKMQjBrAESBDkzMjUY7CAgwTMou6OKAzD3o4oDOFNAAFgBagVCQVNJQ3IIU0VPQjBJUksSCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) ![APG Distribution System](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/GP.gif) Sat, 18 Apr - Mon, 20 Apr BOG Bogotá EOH Medellin £160 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:BOG,to:EOH,departure:18/04/2026TANYT&leg2=from:EOH,to:BOG,departure:20/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:159.50&airProductToken=AQo0CjIIwWISBDU1NjMYwTMgxDsorNWKAzD31YoDOE1AAFgBcgVNT1dWRXoKCNaKARIENTU2Mwo0CjIIwWISBDU1NjQYxDsgwTMo0OyKAzCR7YoDOE1AAFgBcgVNT1dWRXoKCNaKARIENTU2NBIKCAEQARgBKgJHUBgBIgQIARABKAIoAygEMAE) ![Arajet](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DM.gif) Wed, 15 Apr - Sat, 18 Apr MIA Miami MDE Medellin £185 Return found 19 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MIA,to:MDE,departure:15/04/2026TANYT&leg2=from:MDE,to:MIA,departure:18/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:184.44&airProductToken=AQpqCjMIxJoBEgQyMTAxGIwCIPKAASiht4oDMK24igM4wZ4BQABYAWoFQkFTSUNyB0FPQkFTT1cKMwjEmgESBDE3MzgY8oABIOwgKI25igMwqLqKAzjBngFAAFgBagVCQVNJQ3IHQU9CQVNPVwpqCjMIxJoBEgQxNzM3GOwgIPKAASjJ14oDMOHYigM4waABQABYAWoFQkFTSUNyB0FQQkFTT1cKMwjEmgESBDIxMDQY8oABIIwCKNfZigMw49qKAzjBoAFAAFgBagVCQVNJQ3IHQVBCQVNPVxIKCAsQARgIKgJETRgBIgQIARABKAIwAw) ![JetBlue Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/b6.gif) Sun, 8 Mar - Thu, 12 Mar FLL Fort Lauderdale MDE Medellin £191 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FLL,to:MDE,departure:08/03/2026TANYT&leg2=from:MDE,to:FLL,departure:12/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:191.00&airProductToken=AQotCisIwmwSAjQxGOVaIOwgKK-KhwMwhYyHAzhMQABYAWoCRE5yCFBJMFFCRUwxCi0KKwjCbBICNDAY7CAg5Voo8biHAzDFuocDOExAAFgBagJETnIIVUkwUUJFTDESCggBEAEYASoCQjYYASIECAEQASgCKAQoBjAB) ## Find the cheapest month to fly from Columbus (CMH) to Medellín (MDE) ### September is typically the cheapest month to fly From £195 - £497 per traveller. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=FTG_SPRING_PROMO_) ## Frequently asked questions ### What is the name of Santa Cruz's airport? ### How far is Enrique Olaya Herrera Airport (EOH) from central Santa Cruz? ### What airport is best to fly into Santa Cruz? ### How many airlines fly to Santa Cruz? ### Which airlines fly to Santa Cruz? ### How many nonstop flights are there to Santa Cruz? ### Where are the most popular flights to Santa Cruz departing from? ### How long is the flight to Santa Cruz Airport? ### How to book the cheapest flight to Santa Cruz? ### Do you have any tips for my flight to Santa Cruz? > - First of all, put in your passport, travel documents, cash and daily medications. Next, you'll want some entertainment to help pass the time. A thrilling novel and a phone crammed with your favourite shows are always good options. If you hope to catch up on some sleep, a neck pillow and a pair of noise-cancelling headphones will also come in handy. Finally, make room for a toothbrush and some deodorant so you'll arrive looking and feeling fresh. > > > Do not pack the following items in your hand luggage: > > > - Check carefully that you don't have sharp objects (like a pocket knife) hiding in your hand luggage. Other prohibited items include explosive or flammable goods, such as aerosol cans and fuel, and liquids and gels in containers with a capacity of more than 3.4 ounces (100 millilitres). > > > What to wear on a flight: > > > - You'll want to go for comfort over style. Prepare for temperature changes by dressing in layers, and wear closed-toe, flat footwear like slip-ons. > - Deep vein thrombosis (DVT), a blood clot condition caused by extended periods of inactivity, can be a risk on long-haul flights. Make a point of walking around the cabin or do some gentle exercises in your seat to improve your circulation. ### How to get through airport security fast when flying to Santa Cruz? > - Security personnel first need to know that you have a valid ID and travel documents before anything else. Have them within easy reach, ready for inspection. > - After that, both you and your carry-on bag will be X-rayed. To make the process quick and painless, take off anything that is likely to trigger the alarm. Personal belongings like your jacket, belt and earphones will be required to go through the machine. > - All your electronic devices, including your laptop and phone, are also required to be scanned separately. > - Remove all gels and liquids from your carry-on luggage. They usually need to be sent through the X-ray scanner separately. Each item should be in a container no larger than 3.4 ounces (100 millilitres) and everything must fit inside a quart-size (one litre), clear zip-close bag. > - It's also possible you'll be asked to remove your shoes for scanning, so wearing lightweight sneakers is always a smart idea. > - Take all prohibited items out of your carry-on bag. If you have any sharp objects like a pocket knife or tools, put them in your checked baggage. They won't be allowed on board and will be confiscated. ## Book with confidence # Expedia flights to Santa Cruz Searching for cheap flights to Santa Cruz? No travel company presents more choices than Expedia if you're looking to compare flights to Santa Cruz. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Medellin. Expedia provides the cheapest flights to many destinations in Medellin and you may find even greater savings if you combine your flight with a hotel stay in Santa Cruz. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Santa Cruz for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Santa Cruz flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Travel information | Destination airport | José María Córdova Intl. | | ----------------------------- | ------------------------ | | Destination airport IATA code | MDE | | Destination city name | Medellín | | Return price | £87 | ## Trending flights to Santa Cruz Prices were available within the past 7 days and start at £44 for one-way flights and £87 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Mon, 23 Mar - Mon, 20 Apr GLA Glasgow MDE Medellin £647 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GLA,to:MDE,departure:23/03/2026TANYT&leg2=from:MDE,to:GLA,departure:20/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:646.96&airProductToken=AQqnAQoxCMuYARIDOTM0GOYCIICTASjtrogDMMyviAM4TEAAWAFqBUxJR0hUcghHR0xESTdMSQoyCMuYARIDNzU3GICTASDvxAEo7LCIAzCKtogDOEdAAVgBagVMSUdIVHIIR0dMREk3TEkKPgjLmAESBDg4ODUY78QBIOwgKIe3iAMw3LeIAzhUQAFYAWoFTElHSFRyCEdHTERJN0xJegoIw5oBEgQ4ODg1CqcBCj4Iy5gBEgQ4ODQyGOwgIO_EASj48YoDMNDyigM4VkAAWAFqBUxJR0hUcghHR0xESTdMSXoKCMOaARIEODg0MgoyCMuYARIDNzU4GO_EASCAkwEotv2KAzCigosDOEdAAVgBagVMSUdIVHIIR0dMREk3TEkKMQjLmAESAzkzNRiAkwEg5gIow4uLAzCdjIsDOExAAVgBagVMSUdIVHIIR0dMREk3TEkSCggCEAEYAioCS0wYASIECAEQASgCKAMoBDAN) \*Available to Expedia members.