Title: Cheap Flights to Mayesville - Expedia.co.uk ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £484 Cheap Flights to Mayesville [View £484 flight on Tue, 12 May 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:LGW,to:FLO,departure:12/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:483.50&airProductToken=AQqoAQo-CMGCARIENjkzMRjLsQEgzHAo6uSMAzCp6YwDOE9AAFgBagVCQVNJQ3IIT0xYNUM1QjR6CgjCggESBDY5MzEKMgjBggESBDEzNzkYzHAg4poBKIrxjAMw-vGMAzhCQAFYAWoFQkFTSUNyCE9MWDVDNUI0CjIIwYIBEgQ2MDAzGOKaASDlcijD8owDMIbzjAM4QkABWAFqBUJBU0lDcghPTFg1QzVCNBIKCAIQARgCKgJBQRgBIgQIARABKAIoAygEMAs) [Hotels in Mayesville](https://expedia.co.uk/Mayesville-Hotels.d3000456025.Travel-Guide-Hotels)[Mayesville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mayesville.d3000456025.Car-Hire-Guide)[Mayesville Holidays](https://expedia.co.uk/Mayesville.d3000456025.Holidays-City-Breaks) ## Popular airlines to Mayesville - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Mayesville, South Carolina, United States of America,departure:21/03/2026TANYT&leg2=from:Mayesville, South Carolina, United States of America,to:CMH,departure:28/03/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to Mayesville Prices were available within the past 7 days and start at £484 for one-way flights and £765 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, 22 Apr - Wed, 29 Apr LHR London FLO Florence £765 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:FLO,departure:22/04/2026TANYT&leg2=from:FLO,to:LHR,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:764.29&airProductToken=AQpoCjIIwYIBEgM3MzMY64kBIOKaASjUgosDMOuGiwM4QkAAWAFqBUJBU0lDcghPTFg4QzFCNAoyCMGCARIENTg5MxjimgEg5XIoiImLAzDLiYsDOEJAAVgBagVCQVNJQ3IIT0xYOEMxQjQKnAEKMgjBggESBDU5MTEY5XIg4poBKNDQiwMwktGLAzhPQABYAWoFTk9CQUdyCE9MWDhDMUI0CjMIwYIBEgQ1MDc2GOKaASCYzgEok9SLAzCT1YsDOE9AAVgBagVOT0JBR3IIT0xYOEMxQjQKMQjCggESAjkyGJjOASDriQEozdaLAzD72YsDOE9AAVgBagVOT0JBR3IIT0xYOEMxQjQSCggCEAEYAioCQUEYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, 22 Apr - Wed, 29 Apr LHR London FLO Florence £782 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:FLO,departure:22/04/2026TANYT&leg2=from:FLO,to:LHR,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:781.29&airProductToken=AQqoAQo-CMGCARIENzAwNBjriQEgrhwoooKLAzCqhosDOE5AAFgBagVCQVNJQ3IITkxYNEMxQjR6CgjCggESBDcwMDQKMgjBggESBDEwNTIYrhwg4poBKIqHiwMwkYiLAzhCQAFYAWoFQkFTSUNyCE5MWDRDMUI0CjIIwYIBEgQ1ODkzGOKaASDlciiIiYsDMMuJiwM4QkABWAFqBUJBU0lDcghOTFg0QzFCNAqcAQoyCMGCARIENTkxMRjlciDimgEo0NCLAzCS0YsDOE9AAFgBagVOT0JBR3IIT0xYOEMxQjQKMwjBggESBDUwNzYY4poBIJjOASiT1IsDMJPViwM4T0ABWAFqBU5PQkFHcghPTFg4QzFCNAoxCMKCARICOTIYmM4BIOuJASjN1osDMPvZiwM4T0ABWAFqBU5PQkFHcghPTFg4QzFCNBIKCAIQARgCKgJBQRgBIgQIARABKAIoAygEMAE) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Wed, 15 Apr - Wed, 22 Apr LGW London FLO Florence £785 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LGW,to:FLO,departure:15/04/2026TANYT&leg2=from:FLO,to:LGW,departure:22/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:785.00&airProductToken=AQqcAQoyCMKCARIEMjE2NxjLsQEg8wMoiLSKAzDHuIoDOE9AAFgBagVOT0JBR3IIT0xYOEMxQjQKMgjBggESBDMwNTIY8wMg4poBKMK5igMwubqKAzhPQAFYAWoFTk9CQUdyCE9MWDhDMUI0CjIIwYIBEgQ1ODkzGOKaASDlciiku4oDMOi7igM4T0ABWAFqBU5PQkFHcghPTFg4QzFCNAqoAQoyCMGCARIENTkxMRjlciDimgEo8IGLAzCygosDOEJAAFgBagVCQVNJQ3IITkxYNEMxQjQKMgjBggESBDIzMjUY4poBIMxwKJaEiwMwg4WLAzhCQAFYAWoFQkFTSUNyCE5MWDRDMUI0Cj4IwYIBEgQ3MDExGMxwIMuxASi7h4sDML6LiwM4TkABWAFqBUJBU0lDcghOTFg0QzFCNHoKCMKCARIENzAxMRIKCAIQARgCKgJCQRgBIgQIARABKAIoAygEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, 15 Apr - Wed, 22 Apr LHR London FLO Florence £787 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:FLO,departure:15/04/2026TANYT&leg2=from:FLO,to:LHR,departure:22/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:786.29&airProductToken=AQqaAQowCMGCARICODcY64kBIK4cKO2yigMw8LaKAzhCQABYAWoFQkFTSUNyCE9MWDhDMUI0CjIIwYIBEgQyOTQ2GK4cIOKaASjduIoDMOS5igM4QkABWAFqBUJBU0lDcghPTFg4QzFCNAoyCMGCARIENTg5MxjimgEg5XIoqLqKAzDruooDOEJAAVgBagVCQVNJQ3IIT0xYOEMxQjQKnAEKMgjBggESBDU5MTEY5XIg4poBKPCBiwMwsoKLAzhRQABYAWoFTk9CQUdyCFFMWDRDMUI0CjMIwYIBEgQ1MDIwGOKaASCYzgEozIOLAzDRhIsDOFFAAVgBagVOT0JBR3IIUUxYNEMxQjQKMQjCggESAjkyGJjOASDriQEo7YeLAzCbi4sDOFFAAVgBagVOT0JBR3IIUUxYNEMxQjQSCggCEAEYAioCQUEYASIECAEQASgCKAMoBDAB) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Sun, 19 Apr - Sun, 26 Apr LGW London FLO Florence £799 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LGW,to:FLO,departure:19/04/2026TANYT&leg2=from:FLO,to:LGW,departure:26/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:799.00&airProductToken=AQqcAQoyCMKCARIEMjE2NxjLsQEg8wMoiOGKAzDH5YoDOE9AAFgBagVOT0JBR3IIT0xXOEMxQjQKMgjBggESBDMwNTIY8wMg4poBKMLmigMwueeKAzhPQAFYAWoFTk9CQUdyCE9MVzhDMUI0CjIIwYIBEgQ1ODkzGOKaASDlciik6IoDMOjoigM4T0ABWAFqBU5PQkFHcghPTFc4QzFCNAqoAQoyCMGCARIENjAwMxjlciDimgEogLSLAzDFtIsDOEJAAFgBagVCQVNJQ3IIT0xYOEMxQjQKMgjBggESBDMyMDAY4poBIMxwKO-1iwMw17aLAzhCQAFYAWoFQkFTSUNyCE9MWDhDMUI0Cj4IwYIBEgQ3MDExGMxwIMuxASjbv4sDMN7DiwM4T0ABWAFqBUJBU0lDcghPTFg4QzFCNHoKCMKCARIENzAxMRIKCAIQARgCKgJCQRgBIgQIARABKAIoAygEMAE) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=FTG_SPRING_PROMO_) ## Frequently asked questions ### What is the name of Mayesville's airport? ### What airport is best to fly into Mayesville? ### How many airlines fly to Mayesville? ### Which airlines fly to Mayesville? ### How many nonstop flights are there to Mayesville? ### Where are the most popular flights to Mayesville departing from? ### How long is the flight to Mayesville Airport? ### How to book the cheapest flight to Mayesville? ### Do you have any tips for my flight to Mayesville? > - Travelling on a plane can be a comfortable experience if you pack the right things. First things first, you'll need basic toiletry items, such as deodorant and a toothbrush, a fresh set of clothes and a magazine or two. Next, find a spot in your hand luggage for your mobile phone, a charger, any medications and perhaps a comfy neck pillow too. Last, but definitely not least, be sure to take your passport, travel documents and some money. > > > Do not pack the following items in your hand luggage: > > > - While the list of restricted items differs between air carriers, the general guide to follow is avoid carrying anything flammable, sharp or explosive. This includes things like screwdrivers, pocket knives, spray paint and flares. Sporting equipment like ice skates, and items that could harm passengers, such as swords and batons, are also banned from the cabin. > > > What to wear on a flight: > > > - Comfort should be your main priority when choosing what to wear during your flight. Loose, breathable clothing is a smart choice, as are flat, slightly roomy shoes. > - Deep vein thrombosis (DVT), a blood clotting condition caused by prolonged periods of inactivity, can be a risk on long-haul flights. Walk around the cabin and give your legs a stretch or do some simple exercises in your seat to improve your circulation. ### How to get through airport security fast when flying to Mayesville? > - Airport security personnel first need to make sure that you have a valid ID and matching travel documents before anything else. Have them within easy reach, ready for inspection. > - The X-ray machine is up next. Remove anything on you that is likely to set off the alarm. This includes things like headphones or earphones, as well as bulky coats or jackets. They'll need to be placed on the conveyor belt for screening. > - For just a few moments, you'll have to unplug from technology. Your phone, tablet and any other electronics must also be sent through the scanner. > - Any liquids or gels, such as shampoo or hairspray, that you want to bring on board must be no larger than 3.4 ounces (100 millilitres). Also, they all must fit inside a quart-size (one litre), clear zip-lock bag. > - There's a chance you'll be asked to remove your shoes to be X-rayed, so wearing slip-on shoes is always a wise idea. > - Avoid taking prohibited items in your carry-on bag. If you have any sharp or pointed objects, put them in your checked luggage. They won't be allowed in the cabin. ## Book with confidence # Expedia flights to Mayesville Searching for cheap flights to Mayesville? No travel company presents more choices than Expedia if you're looking to compare flights to Mayesville. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to South Carolina. Expedia provides the cheapest flights to many destinations in South Carolina and you may find even greater savings if you combine your flight with a hotel stay in Mayesville. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Mayesville for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Mayesville flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Travel information | Destination airport | Florence Regional | | ----------------------------- | ----------------- | | Destination airport IATA code | FLO | | Destination city name | Florence | | Return price | £764 | ## Trending flights to Mayesville Prices were available within the past 7 days and start at £484 for one-way flights and £765 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, 22 Apr - Wed, 29 Apr LHR London FLO Florence £765 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:FLO,departure:22/04/2026TANYT&leg2=from:FLO,to:LHR,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:764.29&airProductToken=AQpoCjIIwYIBEgM3MzMY64kBIOKaASjUgosDMOuGiwM4QkAAWAFqBUJBU0lDcghPTFg4QzFCNAoyCMGCARIENTg5MxjimgEg5XIoiImLAzDLiYsDOEJAAVgBagVCQVNJQ3IIT0xYOEMxQjQKnAEKMgjBggESBDU5MTEY5XIg4poBKNDQiwMwktGLAzhPQABYAWoFTk9CQUdyCE9MWDhDMUI0CjMIwYIBEgQ1MDc2GOKaASCYzgEok9SLAzCT1YsDOE9AAVgBagVOT0JBR3IIT0xYOEMxQjQKMQjCggESAjkyGJjOASDriQEozdaLAzD72YsDOE9AAVgBagVOT0JBR3IIT0xYOEMxQjQSCggCEAEYAioCQUEYASIECAEQASgCKAMoBDAB) \*Available to Expedia members.