The Best Hotels Closest to Byron Town Square in Byron - 2026 Updated Prices

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Our top choices for Byron Town Square hotels

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A hotel with a covered entrance, multiple floors, and a parking lot.

A hotel room with a large bed, a desk, a chair, and a kitchenette.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

1. Spark by Hilton Rochester South

9.8 mi from Byron Town Square

Stanton

£58

includes taxes & fees

22 Nov - 23 Nov

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern lounge area with a sofa, chairs, and tables.

A modern hotel room with a bed, desk, and kitchenette.

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

7.8 mi from Byron Town Square

howard

£94

includes taxes & fees

6 Nov - 7 Nov

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A compact laundry area with a washing machine, dryer, and a water fountain.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

3. Econo Lodge Mayo Clinic Area

8.6 mi from Byron Town Square

Ashley

£57

includes taxes & fees

15 Nov - 16 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

7.4 mi from Byron Town Square

James

£105

includes taxes & fees

6 Nov - 7 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

5. Hampton Inn Rochester-South

8.5 mi from Byron Town Square

dennis

£77

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A gym with treadmills, elliptical machines, and a stationary bike.

A hotel room with a desk, a chair, a flat-screen TV mounted on the wall, and a lamp on the desk.

A kitchen with a waffle maker, a waffle iron, and a waffle maker instruction manual.

6. Comfort Inn & Suites Rochester South Mayo Clinic

10.8 mi from Byron Town Square

Terri

£66

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a sofa, a small round table, two floor lamps, and a framed picture on the wall.

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

7. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

6.9 mi from Byron Town Square

Brien

£104

includes taxes & fees

6 Nov - 7 Nov

A modern hotel lobby with a reception desk, seating area, and a dining space.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

A Holiday Inn Express building with a stone facade and illuminated signage.

A modern breakfast area with a counter displaying various food items, a water dispenser, and a sign indicating a bakery section.

8. Holiday Inn Express Rochester South - Mayo Area by IHG

9.8 mi from Byron Town Square

Rick

£70

includes taxes & fees

7 Nov - 8 Nov

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A bar with wooden stools and a neon sign.

An indoor swimming pool with a slide, seating area, and a large frog statue.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

9. AmericInn by Wyndham Rochester Near Mayo Clinic

8.4 mi from Byron Town Square

blake

£63

includes taxes & fees

1 Nov - 2 Nov

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A conference room with a long table, multiple chairs, and decorative wall art.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

7.1 mi from Byron Town Square

MATTHEW

£89

includes taxes & fees

6 Nov - 7 Nov

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern kitchen with a built-in microwave, a coffee machine, and a sink.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

11. Staybridge Suites Rochester - Mayo Clinic Area by IHG

7.4 mi from Byron Town Square

Amanda

£100

includes taxes & fees

1 Nov - 2 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

12. Quality Inn & Suites Mayo Clinic Area

8.5 mi from Byron Town Square

Jessica

£59

includes taxes & fees

13 Nov - 14 Nov

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

A hotel room with a bed, bedside table, and a window with curtains.

13. TownePlace Suites by Marriott Rochester Mayo Clinic Area

7.8 mi from Byron Town Square

Cory

£118

includes taxes & fees

6 Nov - 7 Nov

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A reception area with a clock, a counter, and a nameplate.

A hotel gym with treadmills, elliptical machines, and free weights.

A hotel room with a large round table, two sofas, a TV, and a bed.

14. Candlewood Suites Rochester Mayo Clinic Area by IHG

8.4 mi from Byron Town Square

Kevin

£92

includes taxes & fees

15 Nov - 16 Nov

A modern dining area with high tables, chairs, and pendant lighting.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

15. Hampton Inn & Suites Rochester-North

6.9 mi from Byron Town Square

Mark

£88

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A garden with a water feature, rocks, and yellow umbrellas.

16. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

7.9 mi from Byron Town Square

Deanna

£98

includes taxes & fees

4 Nov - 5 Nov

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

A gym with exercise equipment, a clock, and a window with blinds.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

17. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

7.1 mi from Byron Town Square

Lin

£96

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with a reception desk, sofas, and a coffee table.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

A hotel room with a large bed, a sofa, a TV, and a desk.

18. Sleep Inn & Suites West-Near Medical Center

5.4 mi from Byron Town Square

Jacqueline

£68

includes taxes & fees

15 Nov - 16 Nov

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern interior with a large dining table, sofas, and a kitchen area.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

19. The Berkman

7.1 mi from Byron Town Square

Suzette

£144

includes taxes & fees

24 Oct - 25 Oct

A spacious hotel lobby with multiple seating areas, a central column, and large windows allowing natural light.

A hotel room with a large bed, a sofa, a desk with a TV, and a view of the city.

A rooftop terrace with outdoor seating and a city skyline in the background.

A modern indoor swimming pool with clear water, surrounded by lounge chairs and a seating area with a patterned wall.

20. Hilton Rochester Mayo Clinic Area

8.2 mi from Byron Town Square

Jennifer

£153

includes taxes & fees

7 Nov - 8 Nov

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Compare popular hotels close to Byron Town Square

Property	Property class	Guest rating
Spark by Hilton Rochester South	9.2 Wonderful 597 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,001 reviews	View
Econo Lodge Mayo Clinic Area	9.0 Wonderful 1,008 reviews	View
EVEN Hotel Rochester - Mayo Clinic Area by IHG	9.4 Exceptional 1,000 reviews	View
Hampton Inn Rochester-South	9.0 Wonderful 1,001 reviews	View

Top Byron Town Square Hotel Reviews

Sleep Inn & Suites West-Near Medical Center

8/10 Good

"We always stay here on trips to Mayo Clinic. The breakfast is always good. It's a dependable hotel and we've never been disappointed."

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"It is an older motel, but it has been updated, For the most part, it was clean. My only complaint is, I know this is a minor thing, but the silverware at breakfast is absolutely worthless. Better, stronger silverware does not cost that much more."

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"This hotel was very convenient to Mayo, just a five minute walk. It was especially nice to stay so close to mayo and yet avoid dealing with the construction. Parking was easy to get to if you use the ramp across the street from the hotel. Overall the hotel is a bit dated but very clean. The beds could use replacing as the mattress was saggy. We liked having the extra room of a suite as well as the mini kitchen."

Comfort Inn & Suites West - Medical Center

8/10 Good

"The room was very clean and the beds were comfortable. Breakfast was good with lots of options."

Kahler Grand Hotel

8/10 Good

"Can’t go to a Kahler Grand restaurant and get breakfast. They only have room service for breakfast!"

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"Very nice place, convient, clean"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"."

Extended Stay America Suites Rochester North

10/10 Excellent

"Me gustó que todo está muy limpio y la recepción fueron muy amables . Lo que no me gustó fue el desayuno , lo único que tenía fue café , pan y avena"

TownePlace Suites by Marriott Rochester

10/10 Excellent

"It was a great place! The staff was very helpful!"

Other attractions near Byron Town Square

High Point Shopping Center

You can do some window-shopping at High Point Shopping Center during your trip to Byron. Amble around the area's parks or experience its art scene.

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Valley View Park

Valley View Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Community Center Park

Community Center Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Links of Byron Mini Golf

Enjoy a round of golf in Byron at Links of Byron Mini Golf. Amble around the area's parks or experience its art scene.

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Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

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Frequently asked questions

What's the area like around Byron Town Square?

Byron Town Square is located in Byron. You'll find 9 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to Byron Town Square?

AmericInn by Wyndham Rochester Near Mayo Clinic is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and free breakfast. You'll find it 8.4 mi (13.5 km) from Byron Town Square. Other good choices around the area include Kahler Grand Hotel and Med City Inn & Suites - Mayo Clinic Area.

How many hotels should I expect to find near Byron Town Square?

Expedia has 9 hotels and other accommodation options a few miles from Byron Town Square.

If I need to cancel the hotel reservation for my stay near Byron Town Square, will I receive a refund?

Yes! Most hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best deals available near Byron Town Square.

What can I see and do near Byron Town Square?

Explore nature at Oxbow Park and Douglas Trail. A trip to High Point Shopping Center and Cheery Meadows Center might be just the ticket for souvenir shopping. If you're looking for something to do, plan a visit to Links of Byron Mini Golf, Somerby Golf Club and Putting Green while you're in the area.

Search Hotels Near Byron Town Square, Byron

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Our top choices for Byron Town Square hotels

1. Spark by Hilton Rochester South

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

3. Econo Lodge Mayo Clinic Area

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

5. Hampton Inn Rochester-South

6. Comfort Inn & Suites Rochester South Mayo Clinic

7. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

8. Holiday Inn Express Rochester South - Mayo Area by IHG

9. AmericInn by Wyndham Rochester Near Mayo Clinic

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Staybridge Suites Rochester - Mayo Clinic Area by IHG

12. Quality Inn & Suites Mayo Clinic Area

13. TownePlace Suites by Marriott Rochester Mayo Clinic Area

14. Candlewood Suites Rochester Mayo Clinic Area by IHG

15. Hampton Inn & Suites Rochester-North

16. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

17. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

18. Sleep Inn & Suites West-Near Medical Center

19. The Berkman

20. Hilton Rochester Mayo Clinic Area

Compare popular hotels close to Byron Town Square

Top Byron Town Square Hotel Reviews

Sleep Inn & Suites West-Near Medical Center

AmericInn by Wyndham Rochester Near Mayo Clinic

Kahler Inn and Suites - Mayo Clinic Area

Comfort Inn & Suites West - Medical Center

Kahler Grand Hotel

Hyatt House Rochester/Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Extended Stay America Suites Rochester North

TownePlace Suites by Marriott Rochester

Other attractions near Byron Town Square

High Point Shopping Center

Valley View Park

Somerby Park

Community Center Park

East Brookfield Park

Links of Byron Mini Golf

Brook Lawn Park

Somerby Golf Club

Frequently asked questions