Title: The 10 Best 5 Star Hotels in Southeast Massachusetts - 2026 Updated Prices | Expedia.co.uk [Southeast Massachusetts Travel Guide](https://expedia.co.uk/Southeast-Massachusetts.dx6047675)[Hotels in Southeast Massachusetts](https://expedia.co.uk/Southeast-Massachusetts-Hotels.d6047675.Travel-Guide-Hotels)[Holiday Rentals in Southeast Massachusetts](https://expedia.co.uk/Southeast-Massachusetts-Holiday-Rentals.d6047675.Travel-Guide-HolidayRentals)[Flights to Southeast Massachusetts](https://expedia.co.uk/Cheap-Flights-To-Southeast-Massachusetts.d6047675.Travel-Guide-Flights)[Things to do in Southeast Massachusetts](https://expedia.co.uk/Things-To-Do-In-Southeast-Massachusetts.d6047675.Travel-Guide-Activities)[Southeast Massachusetts Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Massachusetts.d6047675.Car-Hire-Guide)[Southeast Massachusetts Holidays](https://expedia.co.uk/Southeast-Massachusetts.d6047675.Holidays-City-Breaks) ![Plymouth which includes a memorial](https://images.trvl-media.com/place/9512/29c2009a-6a76-4ff8-95a2-a34d049193d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Southeast Massachusetts, United States of America - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Massachusetts 5 Star Hotels Tonight [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6047675&startDate=2026-01-09&endDate=2026-01-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6047675&startDate=2026-01-10&endDate=2026-01-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6047675&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6047675&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Massachusetts 5-star hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/13fe4b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/w5695h3900x5y0-3649fa2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/w5700h3895x0y5-016d240d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/c3fa2de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chatham Bars Inn [](https://www.expedia.co.uk/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) Chatham 9.2/10 Wonderful (803 reviews) "Rooms were quaint, clean, and unique. Will definitely be staying again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gustavo £310 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) ![36-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/10000/8600/8504/d518b4f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8600/8504/fc5aa5e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/1000000/10000/8600/8504/b0e1e614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/1000000/10000/8600/8504/7c321ede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor View Hotel [](https://www.expedia.co.uk/Edgartown-Hotels-Harbor-View-Hotel.h8504.Hotel-Information) Edgartown 8.8/10 Excellent (1,000 reviews) "The area was safe and the dining experience was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Albert [](https://www.expedia.co.uk/Edgartown-Hotels-Harbor-View-Hotel.h8504.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Southeast-Massachusetts-Hotels.s50-0-d6047675.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Southeast-Massachusetts-Hotels.s50-0-d6047675.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southeast Massachusetts. ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Resort Cape Cod 1225 Iyannough Rd Hyannis MA [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=12897&PinnedHotelID=12897&HadPinnedHotel=true®ionId=6047675) 8.6/10 Excellent! (424 reviews) [](https://expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Renaissance by Marriott Boston Patriot Place Hotel](https://images.trvl-media.com/lodging/3000000/2580000/2571800/2571800/36fbf750_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Renaissance by Marriott Boston Patriot Place Hotel 28 Patriot Place Foxboro MA £132 8 Feb - 9 Feb includes taxes & fees 9/10 Wonderful! (1,000 reviews) [](https://expedia.co.uk/Foxboro-Hotels-Renaissance-By-Marriott-Boston-Patriot-Place-Hotel.h2571800.Hotel-Information) ![Chatham Wayside Inn](https://images.trvl-media.com/lodging/2000000/1520000/1517300/1517204/1adc0002_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Chatham Wayside Inn 512 Main St Chatham MA £133 11 Jan - 12 Jan includes taxes & fees 9.2/10 Wonderful! (614 reviews) [](https://expedia.co.uk/Chatham-Hotels-Chatham-Wayside-Inn.h1517204.Hotel-Information) Still don't see what you're looking for? [See all properties in Southeast Massachusetts.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6047675&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6047675&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6047675&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6047675&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6047675&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6047675&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Southeast Massachusetts Unmissable purely for its history, this region also offers spectacular coastal scenery and a rich cultural community. [See all hotels in Southeast Massachusetts](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24&adults=2®ionId=6047675) ![National Monument to the Forefathers featuring a statue or sculpture](https://images.trvl-media.com/place/6091769/545d4b07-afa1-46d5-b6a8-78324e701bd5.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Southeast Massachusetts Hotel Reviews ## Find out more about Southeast Massachusetts ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Southeast Massachusetts? > - Search for the lowest price per night from £132 ### What makes a hotel 5 stars in Southeast Massachusetts? ### Are there any 5-star all-inclusive resorts in Southeast Massachusetts? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [2 Star Hotels in Eastern Massachusetts ](https://www.expedia.co.uk/2Star-Eastern-Massachusetts-Hotels.s20-0-d6234158.Travel-Guide-Filter-Hotels) - 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